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Physionic

Nicolas Verhoevenwww.physionic.org
I simplify scientific studies for you. If you want a transparent, detailed source of information for your nutrition, health, performance, etc., welcome to Physionic! JOIN MY PHYSIONIC SOCIAL NETWORK Join my Community [It’s Free!]: https://bit.ly/PhysionicCommunity Join the Physionic Insiders [Premium]: https://bit.ly/PhysionicInsiders HIRE ME FOR CONSULTING: https://bit.ly/3dmUl2H WHERE ELSE IM ACTIVE: Email: http://bit.ly/2AXIzK6 YouTube: http://bit.ly/2JUjXVt Instagram: http://bit.ly/2OBFe7i
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Episodes

Chrono nutrition: Intermittent Fasting improves Insulin Sensitivity INDEPENDENT of Calories

In this episode, we'll be diving head long into a study investigating the first slice of "chrono nutrition" on Physionic. I love this study, because they do several things really well and give us some clear answers regarding intermittent fasting and its impact on insulin sensitivity *independent* of calorie intake (finally!). Study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528549/pdf/nqaa192.pdf Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB ...

Dec 16, 202031 min

Three Mechanisms of Muscle Growth

In this podcast, I decided to jump into an area I've created a decent amount of isolated content and put it into one place. I go into a bit of depth, but not complete depth into three mechanisms of muscle growth - from the classic "muscle damage" to metabolic stress. Knowing this information can easily help us understand how to create training programs that aren't centered around old fashioned thinking - something I'll certainly touch on more, in the future. Books, Courses, and Hire Me: www.phys...

Dec 09, 202033 min

Nutrition for Depression: Obesity, Epigenetics, and Tryptophan (yes, the stuff in turkey)

In this episode, we'll be diving into our third and final part of our "Nutrition on Depression" podcast wherein we'll be touching on depression's link in obesity, epigenetics, and the amino acid tryptophan (the same stuff found in turkey, and many other foods). Hopefully you find some, if not all, the information useful and informative. If you'd like to see the visuals, check out the video version of the podcast, as well. Study: https://www.nature.com/articles/s41380-020-00925-x Video (after 10a...

Dec 02, 202030 min

Nutrition for Depression: The HPA Axis, Brain Derived Neurotrophic Factor, and More [Part 2]

In this episode, we continue our dive into these different nutrients and nutritionally linked reasons why people have worsening depression and what to do against it, nutritionally. This is part 2 of a 3 part podcast series discussing nutrition and its relationship to depression. I'll go into the microbiome, cortisol release from the HPA axis, and BDNF on brain cell growth. Study: https://www.nature.com/articles/s41380-020-00925-x Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JU...

Nov 25, 202048 min

Nutrition on Depression: Nutrients that Help [Part 1]

In this episode, I begin with part 1, wherein we'll be discussing how depression is linked to inflammation, mitochondrial dysfunction, and oxidative stress, as well as several nutrients that can help reduce these effects negatively affecting mental health. Study: https://www.nature.com/articles/s41380-020-00925-x Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6...

Nov 18, 202058 min

Fasting on Skin Health & Skin Aging: A Review

In this episode, I'll be trying my best to make sense of a pretty "all over the place" scientific review that attempts to make sense of how fasting (and calorie deficits) affect skin health, as well as aging. Video Version: https://youtu.be/ihV7hOhAk58 Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6...

Nov 11, 202043 min

Caffeine: Does it make us less insulin sensitive?

In this episode, we dive into a study that investigates the effect caffeine has on insulin sensitivity, but also on a few other parameters, like blood pressure, catecholamines, and free fat. Study: https://care.diabetesjournals.org/content/25/2/364.full-text.pdf Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6...

Nov 04, 202040 min

Creatine on Fat Metabolism, Thermogenesis, ft. Alec Chaves

In this episode, I have the absolute pleasure of welcoming a good friend of mine back to the podcast to discuss a paper he picked out looking at a unique way that creatine affects our fat cells - specifically, the mitochondria within fat cells. Creatine Study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4656041/ Alec's Podcast (Physiology Forum): Apple: https://podcasts.apple.com/us/podcast/the-physiology-forum/id1524358256?id=1524358256&ign-mpt=uo%3D4 iHeartRadio: https://www.iheart.com/po...

Oct 28, 20201 hr 8 min

Women vs Men: Who Gains Muscle Strength Faster?

In this episode, we dive into an extremely simple study that investigates how quickly men and women, compared against one another, gain muscle strength from a resistance training program. Not only that, it touches on some interesting perspectives related to hormones and how the lack of testosterone in women may not be as detrimental as one might imagine - tune in and find out! Study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756754/ Books, Courses, and Hire Me: www.physionic.org YouTube: bit...

Oct 21, 202030 min

10 Day Water Fast INCREASES Inflammation, but is that bad?

In this podcast, we'll be going over a study that touched on an interesting discovery between fat cells and our immune system when a person undergoes an extended (10 day) water fast. Study: https://reader.elsevier.com/reader/sd/pii/S2212877820301563?token=8C7127DDF72DF25D84C3810C2A6673547BFB183F9FA75E6692EA9472DCC7CC12A193097F7212AC3D993955B07CAA1405 Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK...

Oct 14, 202042 min

Does Saturated Fat increase Cholesterol and damage your Liver?

In this episode, I do a deep dive into a study that finally tries to answer if saturated fat increases our cholesterol levels, independent of weight gain. Not only that, it also investigates the impact it has on the liver in terms of fatness - does it cause fatty liver disease? Study: https://academic.oup.com/jcem/article/104/12/6207/5540968 Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6...

Oct 07, 202058 min

Alternate Day Fasting on Cholesterol, Muscle, and Fat-centric Hormones

In this episode, I'll be taking you through a study on alternate day fasting and its affects on cholesterol, fat, muscle, and three unique hormones - all in people without cardiovascular issues, which makes this study that much more unique. Study: https://onlinelibrary.wiley.com/doi/10.1038/oby.2010.54 Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6...

Sep 30, 202045 min

A Light Review of Body Weight "Set Point" Theory

In this podcast, I brush across a variety of concepts and information related to the hypothesis of "body weight set point" that espouses the idea that the body sticks to roughly the same set point in body weight when we attempt to change our weight, the body fights against that imposed change - why? What mechanisms and reasons might there be? Is there a better theory? Study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990627/#bib-010 Books, Courses, and Hire Me: www.physionic.org YouTube: bit....

Sep 23, 202053 min

The Consequences of Extreme Dieting & Low Body Fat

In this episode, I'll be walking us through a case study that recently released on a natural bodybuilder that was followed and measured by researchers for 12 months. They wanted to know how extreme dieting to low single digit body fat would affect testosterone, thyroid hormone, muscle mass, metabolism, and more, and if there were any negative effects, how long would it take to recover? Study: https://pubmed.ncbi.nlm.nih.gov/32898035/ Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly...

Sep 16, 202054 min

High Fat vs High Carb Diets - Which is better for Health? (Blood Pressure, Cholesterol, Leptin, and more)

In this episode, we'll be getting into a study looking at the ketogenic (high fat) diet and its comparison to a calorie restricted low fat diet on various markers of health. Study: https://academic.oup.com/jcem/article/88/4/1617/2845298 Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6...

Sep 09, 202031 min

Can you get coronavirus more than once? Yes. [New Study]

In this episode, I'll be explaining, based on a brand new case study, why the risk for re-infection is present, and what this means for the future of vaccines and herd immunity. Study: https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciaa1275/5897019 Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6...

Sep 02, 202023 min

Do Artificial Sweeteners and Sugar cause Weight Gain and Cravings? A Study weighs in.

In this episode, we cover a study investigating if 4 different artificial sweeteners (Sucralose, RebA, Saccharin, and Aspartame) cause weight gain, insulin issues, spikes in blood sugar, cravings, and more. Study: https://academic.oup.com/ajcn/article/109/5/1288/5475055 Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6...

Aug 26, 202026 min

Supplementing Coenzyme Q10 and migraines... is there a benefit?

In this episode, we'll be looking at a brief clinical trial looking at coenzyme Q10 (CoQ10, ubiquinone) and its affect on migraines in clinically evaluated migraine sufferers. If CoQ10 works, how much was used? How beneficial is it? Are there caveats? All that and more is covered here. Study: https://www.semanticscholar.org/paper/Efficacy-of-coenzyme-Q10-in-migraine-prophylaxis%3A-A-S%C3%A1ndor-Clemente/a3d4701fc58f7747a1cff3ddcd978a0794a50dc2 Books, Courses, and Hire Me: www.physionic.org YouTu...

Aug 19, 202022 min

Is Intermittent Fasting hurtful to Heart Health? Maybe.

In this episode, we'll be diving into a study investigating the role intermittent fasting has on a series of health markers, but specifically on cholesterol and blood pressure - it's not all good news, or is it? Study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2645638/ Books, Courses, and Hire Me: www.physionic.org YouTube: http://bit.ly/2JUjXVt Facebook: http://bit.ly/2PlIOaB Instagram: http://bit.ly/2OBFe7i Email List: http://bit.ly/2AXIzK6...

Aug 12, 202028 min

Plant and Animal Protein associations to Cancer, Heart Disease, and Mortality

In this episode, I discuss a meta-analysis looking into the associations between animal and plant based proteins, as well as total protein, and their relationships to cancer, cardiovascular disease (heart disease, stroke, etc.), and overall mortality. Is plant protein superior? Study: https://www.bmj.com/content/370/bmj.m2412 YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna0...

Jul 29, 202031 min

Making Sense of the Microbiome, ft. Bern Monari

In this episode, I had the pleasure of having a friend and microbiome researcher Bern Monari on to educate us on the microbiome and the research therein. I hope this podcast ends up interesting, because I certainly found it to be, and Bern adds quite a bit to my knowledge of the matter. Enjoy! Bern's LinkedIn (to ask questions): https://www.linkedin.com/in/bernadinemonari/ YouTube: http://bit.ly/2JUjXVt Instagram: http://bit.ly/2OBFe7i Podcast: http://bit.ly/2PThKz0 Email Opt-In: http://bit.ly/2...

Jul 22, 202036 min

Behind the Scenes of a CoVID-19 Vaccine, Side Effects, & Science Explained, ft. David Rach

In this episode, I had the pleasure of having a fellow researcher and class mate David Rach on the podcast to discuss his experience as a participant in a CoVID-19 vaccine trial. However, not only that, he is getting his PhD in Microbiology and Immunology, so he was able to discuss some of the science behind vaccine development, as well as the preliminary results of the trial he was in. David's Info Twitter: @DavidRach2 Facebook Post on the Topic: https://tinyurl.com/yazocyla Vaccine Trial Data:...

Jul 15, 202036 min

Fiber, Stomach Bloating, and Potential Solutions

In this episode, we'll be taking a look at some information on fiber, but more poignantly focused on stomach bloating and how it relates to fiber, as well as some things to consider to lower bloating from the lack or incorrect fiber intake. Fiber & Gas Study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1774297/ YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna0...

Jul 08, 202019 min

Skin Care and Ingredients that Work

In this episode, I go on a monologue wherein I discuss the various ways skin can be damaged and become unhealthy before diving into a few habits and ingredients that have been known to aid in replenishing the health and youth of our skin. YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna0...

Jul 01, 202032 min

Woman Cured of Genetic Disease by Genetic Engineering - The Power of CRISPR

In this episode, I decided to dedicate some time to discussing the brand new reports that a woman suffering from sickle cell anemia has been effectively cured of the disease that would have continued to ruin her life moving forward. The cure wasn't a drug, but the first time use of genetic engineering to cure the disease. Pretty brilliant work on all involved. Article: https://www.npr.org/sections/health-shots/2020/06/23/877543610/a-year-in-1st-patient-to-get-gene-editing-for-sickle-cell-disease...

Jun 24, 202023 min

Balancing Intensity for Effective Home Workouts; How Cancer evades Chemotherapy

In this episode, I discuss two topics. First, we go into how to change the intensity variable when building an effective at home workout program for muscle growth, muscle maintenance, and muscle tone. Secondly, we dive into a bit of cancer and how cancer can "hide" or protect itself against chemotherapies - how does it return? 2:48: Workout at Home 21:35: Cancer & Chemotherapy

Jun 17, 202031 min

United States Medicine in the 1800s; Zoonotic Origin of Viruses

Hey everyone, in this episode, I'll be going into a bit of history on how the United States handled their medical practices in the 1800s by comparison to Europe. I talk about the impact Johns Hopkins University had on the entire medical field in the United States, and then I discuss a bit on zoonotic viruses (viruses that jump from animals to humans). Medical History: 1:36 Zoonotic Virus: 23:04 YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 ...

Jun 10, 202035 min

Spices on Food that fight Cardiovascular Disease & Inflammation; Pain Perception in the Brain

In this episode, we'll be going into a bit of research on pain perception mediated by a particular area of the brain that wasn't pegged as one related to pain. Beyond that, do spices on food reduce inflammation and cardiovascular disease? If so, which ones? Pain (2:01): Thuy Hua, Bin Chen, Dongye Lu, Katsuyasu Sakurai, Shengli Zhao, Bao-Xia Han, Jiwoo Kim, Luping Yin, Yong Chen, Jinghao Lu, Fan Wang. General anesthetics activate a potent central pain-suppression circuit in the amygdala . Nature ...

Jun 03, 202019 min

How much does being Overweight INCREASE Risk of Severe CoVID-19 symptoms? Why are Fit people Dying?

In this episode, I go into two reviews discussing some of the data surrounding being overweight or obese and how much it increases risk of serious issues when dealing with CoVID-19. Also, why are fit people struggling with this infection, and what are some of the presented reasons/mechanisms? Review 1: https://onlinelibrary.wiley.com/doi/epdf/10.1002/oby.22842 Review 2: https://www.ahajournals.org/doi/pdf/10.1161/CIRCULATIONAHA.120.047659 YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagra...

May 20, 202039 min

Understanding Microbes and How Fungi impact Us, ft. Alex Soare

In this episode, I had the absolute pleasure of having yet another smart scientist on the podcast. Alex Soare is on to discuss a bit of basic immunology and microbiology for the first half of the podcast, then we dive into fungi and her expertise on mucormycosis. I hope this proves as informative as I found it (considering I knew nothing about fungi). Alex's Twitter: https://twitter.com/AlexandraYSoare National AWIS Link: https://www.awis.org/ Baltimore AWIS: https://twitter.com/AWISBalt https:/...

May 13, 202054 min
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