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Physionic

Nicolas Verhoevenwww.physionic.org
I simplify scientific studies for you. If you want a transparent, detailed source of information for your nutrition, health, performance, etc., welcome to Physionic! JOIN MY PHYSIONIC SOCIAL NETWORK Join my Community [It’s Free!]: https://bit.ly/PhysionicCommunity Join the Physionic Insiders [Premium]: https://bit.ly/PhysionicInsiders HIRE ME FOR CONSULTING: https://bit.ly/3dmUl2H WHERE ELSE IM ACTIVE: Email: http://bit.ly/2AXIzK6 YouTube: http://bit.ly/2JUjXVt Instagram: http://bit.ly/2OBFe7i
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Episodes

How do Muscles convert Mechanical Force to Molecular signals? Well, its Confusing.

In this episode, I'll (attempt) walk us through two papers that have tried to answer how our muscles convert mechanical force/stimulus into a molecular signal that produce change. It's definitely not concrete and you will have to bear with me, but we're slowly getting to an answer. YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna0...

May 07, 202027 min

Hydroxychloroquine & Remdesivir work against CoVID-19? How?

In this episode, we dive into the big two drug players on the front against CoVID-19 - hydroxycloroquine and remdesivir. Do they work? If so, how do they work? References: Remdesivir: https://www.nih.gov/news-events/news-releases/nih-clinical-trial-remdesivir-treat-covid-19-begins https://www.jbc.org/content/early/2020/02/24/jbc.AC120.013056 Hydroxycloroquine: https://www.medrxiv.org/content/10.1101/2020.03.22.20040758v3 https://www.medrxiv.org/content/10.1101/2020.04.16.20065920v2 https://www.n...

Apr 29, 202030 min

How CoVID-19 affects our Organs (other than the Lungs); Why your Mask is Ineffective and how to Fix it.

In this episode, I dive into a bit of less covered information related to coronavirus CoVID-19 related to the variety of organ systems it affects and how it might be exerting it's effect. I also give some quick information on how to effectively improve your mask that you produce for yourself. Reference: https://www.sciencemag.org/news/2020/04/how-does-coronavirus-kill-clinicians-trace-ferocious-rampage-through-body-brain-toes?fbclid=IwAR1ZjxcdJiFXwSI_FfxhdBscZdT6G6jLc_RPEsnEL99CDe09_r8WE_p9VJc# ...

Apr 22, 202030 min

Transhumanism: Uploading our Consciousness for the Future, ft. Neuroscientist Garrett Bunce

Hi everyone, this is a really special episode, because I had the absolute pleasure of having a super smart friend of mine come on the podcast to discuss a topic he's quite passionate about and on which knows a wealth of information. In this podcast, I discuss the topic of "Transhumanism" with Garrett Bunce. Transhumanism is moored in the idea of traveling consciousness beyond our current existence - can we "upload" our consciousness to a machine and continue our existence? If so, what hurdles ar...

Apr 15, 202055 min

Coronavirus Q&A; Bad Study on Effectiveness of Masks

In this episode, we'll be continuing our discussion of CoVID-19 coronavirus, as well as jumping into a bit of data in a study discussing the effectiveness of masks. Study: https://www.nature.com/articles/s41591-020-0843-2/figures/1 Video: YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna0...

Apr 08, 202036 min

Responding to the Coronavirus Conspiracy Theorists

In this episode, I spend the entire time discussing the multitude of comments I have (and will) receive on my latest coronavirus video - hopefully you get some information out of it, at least. Coronavirus Video: https://www.youtube.com/watch?v=j1lcAINElzY YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna0...

Mar 25, 202056 min

Everything Coronavirus: How long until you show symptoms? Is a 14 day quarantine enough? How to workout in quarantine?

In this episode, we will dedicate the entire podcast talking about the coronavirus (COVID-19) - how long until you show symptoms of the infection? Is a standard 14 day quarantine efficient? And, if you're stuck at home without workout equipment, how do you still make fitness progress with in resistance training? Coronavirus video (with images and data): https://youtu.be/aNqL76phkik YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit....

Mar 18, 202032 min

Longer Pregnancy & Genetics Changes; BioInk Printing Skin; Nuances in reading Studies; Coronavirus is Local...

In this episode, I cover a broad range of topics from pregnancy length and its affect on children's genetics, as well as a new technology that makes printing skin a new therapy possible. Finally, I answer a question/concern a commenter had over why scientists waste their time with "obvious questions". 1:48 - Pregnancy Merid, S.K., Novoloaca, A., Sharp, G.C. et al. Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age. G...

Mar 04, 202032 min

High Protein Diets implicated in Artery Plaques; Air Pollution & Heart Attacks; Ranting on Selective Bias

In this episode, I discuss a paper looking at high protein diets and their impact on atherosclerosis, as well as air pollution and its correlation with heart attacks, and the final half is me ranting on how selective people get to fit their biases. Poor Sleep & Obesity (2:09) https://www.sciencedaily.com/releases/2020/02/200217085214.htm High Protein (7:34) https://www.sciencedaily.com/releases/2020/01/200123152614.htm Air Pollution (12:58) https://www.sciencedaily.com/releases/2020/02/20021...

Feb 26, 202034 min

Phospholipase on Muscle Growth; Autophagy in Cancer and a Mystery Ally; New Antibiotic

In this episode, we will be diving extensively into a powerful muscle promoting mechanism known as phospholipase. Following that, we dive into a potential treatment for cancer using an unlikely ally. Finally, I discuss research out of McMaster University developing a new style of antibiotic. Phospholipase (1:18) https://www.youtube.com/watch?v=EtV3yWw0hz8&t=3s Cancer & Unlikely Ally (19:20) Xue Zhang, Tingting Zhang, John N. Davis, Andrea Marzi, Anthony M. Marchese, Michael D. Robek, Ant...

Feb 19, 202033 min

How does your Body fix Mutations?, Heart Rate Variability, Caffeine causes Migraines?

In this podcast, I admittedly nerd out a bit on genetics and how our cells repair our genes when exposed to mutagens (things that cause mutations). However, with good reason, because a new paper has added some clarity to a part of the process and man is it cool! Beyond that, we will go into heart rate variability, as well as if caffeine is associated with migraines? Check it out and share! Rad DNA Repair, 1:03 Roxanne Oshidari, Richard Huang, Maryam Medghalchi, Elizabeth Y. W. Tse, Nasser Ashgri...

Feb 12, 202039 min

Spontaneous, life threatening, meat allergies; ageotyping; cellular asthma, and more

In this week's episode, we will be discussing many subjects ranging from sudden meat allergies, how asthma presents itself (cellularly), to different "styles" of aging known as ageotypes, as well as even more! Topics and time stamps listed here: Meat Allergy (2:37): https://www.jimmunol.org/content/203/4/813 Selective Asthma (10:50): https://www.nature.com/articles/s41590-019-0496-9 Skin Pain Sensation (19:38): https://science.sciencemag.org/content/365/6454/695 Ageotypes (26:10): https://www.na...

Jan 29, 202036 min

Diet on Male Fertility, Non-HDL Cholesterol on Heart Disease

In this episode, we will go over three articles describing the affect genetics play on cardiovascular disease, as well as sleep's mitigating role. We will also discuss how non-HDL cholesterol affects heart disease risk. Finally, we briefly discuss a study on extreme sugar consumption and its impact on male fertility. (2:28) Genetics & Sleep: Mengyu Fan, Dianjianyi Sun, Tao Zhou, Yoriko Heianza, Jun Lv, Liming Li, Lu Qi. Sleep patterns, genetic susceptibility, and incident cardiovascular dise...

Jan 22, 202033 min

5 Laws of Health, Winning the War on Cancer, Creatine on Muscle Hypertrophy

In this episode, we take a deeper look at a recent video I released on YouTube wherein I describe 5 immutable "laws" of health. Then, we will discuss two bits on cancer research - one wonderful and one interesting. Finally, we finish off with a discussion of "does creatine increase muscle mass directly?" 6:18 - 5 Laws of Health 22:12 - War on Cancer 30:00 - Ketones and Breast Cancer 40:47 - Creatine direct affect on Muscle Hypertrophy? Ketones on Cancer: https://www.physionic.org/overexpressingk...

Jan 16, 202051 min

Endometriosis: Cause of Pain? Treatments? Diagnosis? Symptoms? and More, Ft. Alyssa Dotson

This week's episode is an intriguing one as it involves an in-depth dive into the condition known as endometriosis. I am joined by Alyssa Dotson, who had endometriosis and spent several years reading up on the condition. We dive into treatment, diagnosis, her story, what endometriosis is, as well as a study that claims to have found the cause of endometriosis pain, as well as much more. Time Stamps: What is Endometriosis? (2:02) What causes Endometriosis? (3:08) Signs & Symptoms? (6:49) How ...

Jan 08, 20201 hr 8 min

Dogs for Mental Health, Balancing Blood pH, Sleeplessness on Food Choices

In this episode, you will hear a little bit on how dogs may have an effect in regards to mental health, how the body uses a particular reaction to control blood pH (acidity and alkalinity), how sleep impacts our food choices (or, the lack thereof), and more. Check it out! 3:29 - Dogs 12:09 - Blood pH 27:32 - Sleep & Food Choice 34:49 - Calorie Deficit & Lifespan Reference: Robert Yolken, Cassie Stallings, Andrea Origoni, Emily Katsafanas, Kevin Sweeney, Amalia Squire, Faith Dickerson. Ex...

Dec 27, 201947 min

Infrared Sauna for Heart Disease?

In this episode, we dive into how infrared sauna therapy may or may not be beneficial for endothelial function/heart disease. Study, Notes, & Amendments: https://www.physionic.org/infraredsaunaforheartdisease YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna0...

Dec 19, 201914 min

A Benefit of Starting an Exercise Lifestyle Early

In this episode, I discuss why it is imperative to start your exercise life early in this particular regard - your bones. YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna0

Dec 18, 20195 min

Why does our skin age?

In this episode, I describe a few different mechanisms for why our skin ages through the discovered differences between elderly skin and young skin. Study, Notes, & Amendments: https://www.physionic.org/collagenproductioninagedskin YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna0...

Dec 17, 201923 min

Selective Autophagy & Longer Life

In this episode, I discuss some research wherein scientists have gotten some clues between autophagy and longer life based on a protein called p62. Reference: Caroline Kumsta, Jessica T. Chang, Reina Lee, Ee Phie Tan, Yongzhi Yang, Rute Loureiro, Elizabeth H. Choy, Shaun H. Y. Lim, Isabel Saez, Alexander Springhorn, Thorsten Hoppe, David Vilchez, Malene Hansen. The autophagy receptor p62/SQST-1 promotes proteostasis and longevity in C. elegans by inducing autophagy . Nature Communications , 2019...

Dec 16, 201910 min

Klotho for Cognition and Lifespan

In this episode, I describe a positive mutation that occurs in some people leading them to have enhanced cognitive ability and longer life. Study, Notes, & Amendments: https://www.physionic.org/klothooncognition YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna0...

Dec 12, 201911 min

Dietary Cholesterol - Okay or Not?

In this episode, we dive into dietary cholesterol and its impact on the body as it relates to increasing serum/blood cholesterol levels. YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna0

Dec 11, 20197 min

Fat Loss, Libido, and Sexual Function

In this episode, I take some time and explain what I've discovered in my reading of many studies on the topic and tracing the possible reasons for differences in libido and sexual function with fat loss. Article, Video, and References: https://www.physionic.org/fatlossandsexdrive [Video will be live at 11am ET today] YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna0...

Dec 10, 201915 min

The Longest Heart Attack in History, Sensual Recalibration

In this episode, I discuss the longest heart attack in Spanish history and how a woman SURVIVED after being "dead" for 6 hours. Not only that, I discuss research investigating the retooling of the mammalian brain network under new circumstances. Heart Attack (1:14): https://www.bbc.com/news/uk-50681489 Brain Sensing (8:42): Krystyna Solarana, Ji Liu, Zac Bowen, Hey-Kyoung Lee, Patrick O. Kanold. Temporary visual deprivation causes decorrelation of spatio-temporal population responses in adult mo...

Dec 09, 201916 min

The Sunshine Vitamin

In this episode, I go through a dialogue I wrtoe some time ago discussing the physiology and implications of the "sunshine vitamin" (Vitamin D). YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna0

Dec 06, 20195 min

Curcumin completely eliminates Diabetes risk

In this episode, I briefly discuss one tiny piece of high impact data wherein diabetes risk is completely eliminated by curcumin supplementation. YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna0

Dec 05, 20192 min

Does Metabolism REALLY slow with Age?

In this episode, we will go into a bit of detail on metabolism and why it likely does not REALLY slow with age all that much. YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna0

Dec 04, 20197 min

Tumors SHARE their Cancer

In this brief episode, I discuss a paper wherein the researchers discover that multiple tumors will share, or "cross pollinate" or "self-seed" themselves by sharing cancerous cells. Study, Notes: https://www.physionic.org/cancerselfseeding YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6 Patreon: bit.ly/2OBBna0...

Dec 03, 20193 min
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