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Physionic

Nicolas Verhoevenwww.physionic.org
I simplify scientific studies for you. If you want a transparent, detailed source of information for your nutrition, health, performance, etc., welcome to Physionic! JOIN MY PHYSIONIC SOCIAL NETWORK Join my Community [It’s Free!]: https://bit.ly/PhysionicCommunity Join the Physionic Insiders [Premium]: https://bit.ly/PhysionicInsiders HIRE ME FOR CONSULTING: https://bit.ly/3dmUl2H WHERE ELSE IM ACTIVE: Email: http://bit.ly/2AXIzK6 YouTube: http://bit.ly/2JUjXVt Instagram: http://bit.ly/2OBFe7i
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Episodes

16/8 Intermittent Fasting, without Calorie Counting, on Weight & Health

In this episode, we'll dissect a study wherein the researchers attempt to find out how an unrestricted intermittent fasting protocol works for overweight individuals in aspects of weight, muscle, metabolism, and cardiovascular outcomes like cholesterol, blood sugar, insulin, and so on. Video Podcast: https://youtu.be/TjEKr7ysbfI Study: https://pubmed.ncbi.nlm.nih.gov/32986097/ MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING - 'Understanding Creatine' Book: https://bit.ly/31GxkSN - Hire Me: h...

Aug 12, 202130 min

Questions & Answers: Protein Threshold, Origin of CoVID, Protein on Lifespan, and More.

This week, I return by simply answering questions you guys sent me on Instagram and YouTube. MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING - 'Understanding Creatine' Book: https://bit.ly/31GxkSN - Hire Me: https://bit.ly/3dmUl2H - Content Requests: https://bit.ly/2QOVHLX SUBSCRIBE TO OTHER SOURCES OF MY CONTENT [FREE] - Instagram (@Physionic_PhD): http://bit.ly/2OBFe7i - Facebook (Physionic): http://bit.ly/2PlIOaB - Twitter (@PhysionicPhD): http://bit.ly/2POhuBs - Email List: http://bit.ly...

Aug 05, 202125 min

Protein for Optimal Muscle Growth: Type, Timing, Amount, and More

In this episode, I cover a scientific review on the literature of protein for muscle growth. We'll be covering protein total amount, timing, type, differences in men and women, aging, and more. Enjoy. Video Podcast: https://youtu.be/7h-kLKmknEo Scientific Review: https://link.springer.com/article/10.1007/s40279-019-01053-5 MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING - 'Understanding Creatine' Book: https://bit.ly/31GxkSN - Hire Me: https://bit.ly/3dmUl2H - Content Requests: https://bit.l...

Jul 22, 202153 min

Elevated Blood Fats Change our Mitochondria Behavior & Autophagy

In this episode, we investigate how elevated blood fats change how our mitochondria "behave" and its affect on autophagy. Video Podcast: https://youtu.be/g6JJzVkYM7I Study: https://www.sciencedirect.com/science/article/abs/pii/S0026049521001037 MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING - 'Understanding Creatine' Book: https://bit.ly/31GxkSN - Hire Me: https://bit.ly/3dmUl2H - Content Requests: https://bit.ly/2QOVHLX SUBSCRIBE TO OTHER SOURCES OF MY CONTENT [FREE] - Instagram (@Physioni...

Jul 15, 202129 min

Saturated vs Unsaturated Keto on Cholesterol & Insulin Sensitivity [Starting to get Answers]

In this podcast, I dive deeper into yet another study comparing the ketogenic diet for blood cholesterol, with the added bonus of briefly touching on insulin sensitivity. In this episode, we start to recognize the key difference between a healthy ketogenic diet and an unhealthy ketogenic diet. Study: https://pubmed.ncbi.nlm.nih.gov/15070924/ Video Podcast: https://youtu.be/KEcyW496KGA MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING - 'Understanding Creatine' Book: https://bit.ly/31GxkSN - Hi...

Jul 08, 202122 min

Ketogenic Diet increases Cholesterol in Healthy Women

In this episode, we'll be going again into the ketogenic diet, but the context hath changed as the people being tested are healthy and young, non-overweight, unlike previous studies. There are some other caveats, as well, that we'll go into, so buckle up and let's dive in. Study: https://pubmed.ncbi.nlm.nih.gov/30408717/ Video Podcast: https://youtu.be/bX1cax3zvfQ MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING - 'Understanding Creatine' Book: https://bit.ly/31GxkSN - Hire Me: https://bit.ly...

Jul 01, 202124 min

Intermittent Fasting + Exercise on Muscle, Fat, Blood Sugar, Inflammation & More

In this episode, we dive into a study looking at how 16 hour intermittent fasting affects a variety of health outcomes when paired with resistance training in non-beginner lifters. Study: https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-016-1044-0 Video Podcast: https://youtu.be/2B99DJwPMCk MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING - 'Understanding Creatine' Book: https://bit.ly/31GxkSN - Hire Me: https://bit.ly/3dmUl2H - Content Requests: https://bit.ly/2QOVHLX...

Jun 24, 202141 min

Overweight? High Cholesterol? High Blood Sugar? Keto it away.

In this episode, the 'keto hater' takes on a study that simply investigates the effects from the ketogenic diet in bodyweight, cholesterol, and blood sugar in people who are overweight. Study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2716748/pdf/ecc09200.pdf Video Podcast: https://youtu.be/bsH1qubGSB8 MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING - 'Understanding Creatine' Book: https://bit.ly/31GxkSN - Hire Me: https://bit.ly/3dmUl2H - Content Requests: https://bit.ly/2QOVHLX SUBSCRIB...

Jun 17, 202127 min

The End Replication Problem (Telomeres) & Cellular Senescence

In this episode, we'll be beginning our look at senescent cells, how and why they occur, as well as the main drivers of senescence in aging and disease. Video Podcast: https://youtu.be/NcBpJv5WIhY Scientific Review: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748990/pdf/JCB_201708092.pdf MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING - 'Understanding Creatine' Book: https://bit.ly/31GxkSN - Hire Me: https://bit.ly/3dmUl2H - Content Requests: https://bit.ly/2QOVHLX SUBSCRIBE TO OTHER SOURC...

Jun 10, 202131 min

How do Saturated Fats affect Mitochondria?

In this episode, we'll be discussing how different types of saturated and unsaturated fats impact mitochondria in our muscle cells. Video Podcast: https://youtu.be/2T9I1FmlFyE Study: https://link.springer.com/content/pdf/10.1007/s00125-005-1895-z.pdf MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING - 'Understanding Creatine' Book: https://bit.ly/31GxkSN - Hire Me: https://bit.ly/3dmUl2H - Content Requests: https://bit.ly/2QOVHLX SUBSCRIBE TO OTHER SOURCES OF MY CONTENT [FREE] - Instagram (@Ph...

Jun 03, 202121 min

The 'Keto Damages the Heart' Critique, and My Nutrition

In this episode, I discuss some of the valid and non-valid (by my estimation) critiques of the recent ketogenic diet study I covered on the YouTube channel. I also discuss the nutrition style that I follow, specifically. Video Podcast: https://youtu.be/eE2QpdRSeFY Keto Damages the Heart Video: https://youtu.be/CAkjoT28yZw Keto Damages the Heart Podcast: https://youtu.be/lpns8gfR3H8 MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING - 'Understanding Creatine' Book: https://bit.ly/31GxkSN - Hire ...

May 27, 202134 min

Emilin Deficiency leads to High Blood Pressure

In this episode, I discuss a study looking at how a protein (Emilin) and a molecule (TGF-beta) create a scenario in which high blood pressure occurs in animals *and* in the same effect is seen in humans with high blood pressure. Study: https://pubmed.ncbi.nlm.nih.gov/30354220/ Video Podcast: https://youtu.be/88GqvZ2XjrM MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING - 'Understanding Creatine' Book: https://bit.ly/31GxkSN - Hire Me: https://bit.ly/3dmUl2H - Content Requests: https://bit.ly/2...

May 20, 202140 min

Why Cancer feeds on Sugar

In this episode, I discuss how, and potential reasons why, cancer cells feed off sugar/glucose. Scientific Review: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783224/ Video Podcast: https://youtu.be/vszypCVgpaE MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING - 'Understanding Creatine' Book: https://bit.ly/31GxkSN - Hire Me: https://bit.ly/3dmUl2H - Content Requests: https://bit.ly/2QOVHLX SUBSCRIBE TO OTHER SOURCES OF MY CONTENT [FREE] - Instagram (@Physionic_PhD): http://bit.ly/2OBFe7i - ...

May 12, 202134 min

How does Alcohol affect your Muscle Growth? Let's discuss the Data.

In this episode, we go into a study that investigates if alcohol affects our muscle growth potential by specifically looking at muscle protein synthesis, as well as some proxy markers of protein breakdown. Study: https://pubmed.ncbi.nlm.nih.gov/24533082/ Video Podcast: https://youtu.be/CaRPAx9gL4U MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING - 'Understanding Creatine' Book: https://bit.ly/31GxkSN - Hire Me: https://bit.ly/3dmUl2H - Content Requests: https://bit.ly/2QOVHLX SUBSCRIBE TO OTH...

May 05, 202126 min

I Published a Study (On a New Mechanism for Autophagy)

This is an involved one, but if you care to join me as I explain my recent publication with my lab wherein we discover and describe a new pathway by which autophagy is mediated in cells, then you'll learn some cutting edge science. My Study: https://www.researchgate.net/publication/350870898_Parkin-independent_mitophagy_via_Drp1-mediated_outer_membrane_severing_and_inner_membrane_ubiquitination Video Podcast: https://youtu.be/QmX5xN3H7aU MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING - 'Und...

Apr 28, 20211 hr 8 min

A Medical Research Lecture on Heart Aneurysms [Marfan Syndrome]

This podcast gets really nitty gritty in that it discusses the intracellular signaling pathways and the association between smooth muscle cells and a protein rich foundation known as the extracellular matrix - what causes this weakness in the aorta of the vascular system leading to aneurysm formation? Find out. Study: https://youtu.be/YlQtTdj2eLo Video Podcast: https://youtu.be/YlQtTdj2eLo MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING - 'Understanding Creatine' Book: https://bit.ly/31GxkSN...

Apr 14, 202152 min

Excessive Exercise changes how our Mitochondria behave? [Mitochondrial Dynamics] 2

In this episode, we finish up from last week by discussing how mitochondrial "behavior" is affected by excessive exercise, as well as its impact on mitochondrial reactive oxygen generation, which can cause damage to our cells. Study: https://www.sciencedirect.com/science/article/abs/pii/S1550413121001029?via%3Dihub MY BOOKS, COURSES, VIDEO REQUESTS, & CONSULTING - 'Understanding Creatine' Book: https://bit.ly/31GxkSN - Hire Me: https://bit.ly/3dmUl2H - Content Requests: https://bit.ly/2QOVHL...

Apr 07, 202137 min

Is too much exercise detrimental to our mitochondria and blood sugar regulation?

In this episode, I cover a brand spankin' new study wherein the researchers attempt to answer the question of overdoing exercise and its impact on muscle mitochondria, as well as blood sugar regulation. Study: https://www.sciencedirect.com/science/article/abs/pii/S1550413121001029?via%3Dihub Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6...

Mar 31, 202159 min

Weight Loss and its affect on Metabolic Adaptation

In this episode, we take a look at a study that investigates the impact weight loss/calorie restriction has on metabolic adaptation; we also briefly discuss the idea of metabolic "damage". This is one of a few episodes that I'll be using to cover the topic of metabolic adaptation. Study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328781/?fbclid=IwAR3WSvSpNLzgnwfGh_xyAEx4Txh9z91LnjbW2CFrbbzSS0cM-47MGL4eUxU Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/...

Mar 24, 202144 min

Ketogenic Diet & Ketosis leads to Heart Cell Death [Study Breakdown]

In this episode, I take us on a brief breakdown of a study looking at the ketogenic diet and its impact on heart cell death, heart size, and mitochondrial content. Some intriguing, potentially alarming, results here, but we'll see what interpretations we can really make on this data - dive in with me! Study: https://www.nature.com/articles/s41392-020-00411-4 Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.l...

Mar 17, 202139 min

Burning More Fat DOES NOT mean losing more BODY FAT

In this episode, I attempt to make it as clear as possible, by comparison of high fat/keto to high carbohydrate diets and how they differ in their ability produce body fat loss, although one promotes greater fat burning/oxidation. Video Podcast (available at 10am ET): https://youtu.be/Ns0tXvLI-OI Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6...

Mar 10, 202133 min

Metabolic Flexibility: Switching from Carbs to Fat, and Back Again

In this episode, I give a bit of a higher level view on metabolic flexibility - what is it? Why is it important? Instances of it? How to improve it? That's all covered in this podcast - enjoy! Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6...

Mar 03, 202125 min

Does Water Fasting increase our Mitochondria?

In this episode, I briefly cover certain aspects of a study that looks into how effective fasting, specifically multi day water fasting, affects our mitochondrial content in our cells (muscle). Video Podcast: https://youtu.be/KMU1OcGjjLw Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6...

Feb 17, 202117 min

I ran an Experiment on Myself [Muscle Maintenance] and Your Questions Answered

In this episode, I cover more detail on an experiment I decided to try on myself over the last 10 months wherein I try to maintain my muscle with minimal effort. I answer questions from 10 people who wrote questions out on how I pulled it off, as well as other questions related to fat loss and muscle perseveration. Video being Discussed [I Ran an Experiment on Myself]: https://youtu.be/qtim_tXkVoQ Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Ins...

Feb 10, 202129 min

Mutations that affect Muscle Fusion

In this podcast, we'll be going over a presentation I gave in one of my courses on Muscle Biology - specifically, how certain mutations in a gene can impede muscle cells' ability to fuse, and on top of that, why some people survive it and why others do not. Study: https://www.nature.com/articles/ncomms16077 Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6...

Feb 03, 202148 min

You Can't Have it All [Lifespan vs Health span]

There is no human condition wherein you will be at peak form in multiple areas. Much like the idea of the generalist vs the specialist - your body can't be a specialist in all ways, and in the same vein, there is no diet that will be the "ultimate" diet that will help you achieve peak-ness in all areas. The discussion of lifespan vs health span is a great example of that, as well as the idea of growth and uncontrolled growth (cancer). My Creatine Book and Course: http://bit.ly/3sfLLJN YouTube: b...

Jan 27, 202123 min

Fasting and Calorie Counting: Which stimulates Hunger Hormones? [Leptin, MSH, AgRP]

In this content, I dive into a study looking into three hunger related hormones and the effect water fasting and calorie counting have, in obese and lean individuals, on three hunger hormones - leptin, melanocyte stimulating hormone (MSH), and Aguiti Related Protein (AgRP). Does fasting stimulate these hormones or does calorie counting? Does obesity play a factor? Find out! Study: https://pubmed.ncbi.nlm.nih.gov/15212642/ My Creatine Book and Course: http://bit.ly/3sfLLJN YouTube: bit.ly/2JUjXVt...

Jan 20, 202121 min

Fractalkine: A marker for Alzheimer's and Neuroinflammation

In this episode, I discuss a molecule I ran across when listening to the Joe Rogan Experience. This molecule, known as fractalkine, has some unique characteristics and potential implications in a series of different diseases and brain related health outcomes - mostly related to inflammation in the brain. Review: https://pubmed.ncbi.nlm.nih.gov/26084002/ My Creatine Book and Course: http://bit.ly/3sfLLJN YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly...

Jan 13, 202133 min

Three UNKNOWN Benefits of Creatine [Muscle, Brain, and Inflammation]

In this episode, we briefly discuss three ways that creatine positively affects us in muscle, the brain, and inflammation. I also introduce my first paid content that I spent most of 2020 working on, as well as a new website for your viewing pleasure - it was a busy 2020 for me! Creatine Book and Course: https://www.physionic.org/booksandcourses Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instagram: bit.ly/2OBFe7i Email List: bit.ly/2AXIzK6...

Jan 06, 202122 min

ASP: The Ketogenic Fat Storage Hormone

In this episode, I go into a bit more detail on a topic I've just started releasing content on (in video form). This subject is on a hormone that also leads to fat storage, much like insulin, yet many keto espousing gurus either ignore or are not aware of it; this is convenient, since this hormone is stimulated by fat consumption, not carbohydrate consumption (the exact anti-thesis to insulin). Books, Courses, and Hire Me: www.physionic.org YouTube: bit.ly/2JUjXVt Facebook: bit.ly/2PlIOaB Instag...

Dec 30, 202029 min
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