In this episode Dr Naiman talks about metabolic health and how it is the same thing as body composition and what we can do to have the best metabolic health. Dr. Ted Naiman is a board-certified Family Medicine physician in the department of Primary Care at a leading medical center in Seattle. His personal research and medical practice are focused on the practical implementation of diet and exercise for health optimization. He is the author of ‘The PE Diet’. In the book Dr Naiman explains the pro...
Jan 01, 2023•11 min•Season 21Ep. 6
Dr. Ted Naiman is a board-certified Family Medicine physician in the department of Primary Care at a leading medical center in Seattle. His personal research and medical practice are focused on the practical implementation of diet and exercise for health optimization. He is the author of ‘The PE Diet’. In the book Dr Naiman explains the protein to energy ratio and how to use it to optimize food and exercise choices. Dr Naiman's personal site https://tednaiman.com/ The Protein Percent calculator ...
Dec 28, 2022•6 min•Season 21Ep. 5
In this episode Dr Naiman talks how protein is absorbed into the body, what would be a good eating pattern and the difference between plant and animal proteins. Dr. Ted Naiman is a board-certified Family Medicine physician in the department of Primary Care at a leading medical center in Seattle. His personal research and medical practice are focused on the practical implementation of diet and exercise for health optimization. He is the author of ‘The PE Diet’. In the book Dr Naiman explains the ...
Dec 25, 2022•9 min•Season 21Ep. 4
In this episode Dr Naiman talks about how mTOR is activated and why our metabolic health is of much greater importance than the amount of protein that we eat. Dr. Ted Naiman is a board-certified Family Medicine physician in the department of Primary Care at a leading medical center in Seattle. His personal research and medical practice are focused on the practical implementation of diet and exercise for health optimization. He is the author of ‘The PE Diet’. In the book Dr Naiman explains the pr...
Dec 21, 2022•8 min•Season 21Ep. 3
In this episode Dr Naiman provides a more practical view on the PE Diet. What P:E ratio we should aim for, what is an optimal protein intake and how to find the P:E ratio for various foods. Dr. Ted Naiman is a board-certified Family Medicine physician in the department of Primary Care at a leading medical center in Seattle. His personal research and medical practice are focused on the practical implementation of diet and exercise for health optimization. He is the author of ‘The PE Diet’. In the...
Dec 18, 2022•11 min•Season 21Ep. 2
In this episode Dr Naiman talks about his personal journey through various diets to his formulation of the PE Diet. Dr Ted Naiman is a board-certified Family Medicine physician in the department of Primary Care at a leading medical center in Seattle. His personal research and medical practice are focused on the practical implementation of diet and exercise for health optimization. He is the author of ‘The PE Diet’. In the book Dr Naiman explains the protein to energy ratio and how to use it to o...
Dec 14, 2022•14 min•Season 21Ep. 1
In this episode Dr Cohen talks about the current interventions that he sees as having the most potential but also about the need for precision medicine as there are many causes for Alzheimer's, diabetes etc. and to treat the disease we need to understand the underlying cause. This also would involve changes in the way trials are run, to be able to identify the markers appropriate for each intervention Mitochondrial DNA variation in Alzheimer’s disease reveals a unique microprotein called SHMOOSE...
Dec 11, 2022•10 min•Season 20Ep. 7
In this video Dr Cohen talks CohBar, a company that he co-founded with Professor Nir Barzilai and some of the work they are doing, as well as the latest developments in his lab. He also discusses the need for precision medicine in addressing diseases of aging. Mitochondrial DNA variation in Alzheimer’s disease reveals a unique microprotein called SHMOOSE https://www.nature.com/articles/s41380-022-01769-3 Professor Pinchas Cohen is the dean of the USC Leonard Davis School of Gerontology. He is a ...
Dec 07, 2022•7 min•Season 20Ep. 6
In this video Dr Cohen talks about how mitochondria age and how they are not all the same but different in each tissue. Mitochondrial DNA variation in Alzheimer’s disease reveals a unique microprotein called SHMOOSE https://www.nature.com/articles/s41380-022-01769-3 Professor Pinchas Cohen is the dean of the USC Leonard Davis School of Gerontology. He is a pioneer in the emerging science of mitochondria-derived peptides and their possible therapeutic benefits for diabetes, Alzheimer's and other ...
Dec 04, 2022•6 min•Season 20Ep. 5
In this episode Dr Cohen talks about humanin, SHLEP2 and MTOS-c, how these impact our health, how this varies with ethnicity and age. Professor Pinchas Cohen is the dean of the USC Leonard Davis School of Gerontology. He is a pioneer in the emerging science of mitochondria-derived peptides and their possible therapeutic benefits for diabetes, Alzheimer's and other diseases of aging, an area which remains the focus of his current research. Mitochondria-derived peptides in aging and healthspan htt...
Nov 30, 2022•10 min•Season 20Ep. 4
In this episode Dr Cohen talks about SHMOOZE a new MDP that his lab has discovered and recently published a paper on. He also discusses SNPs, mutations in the MOTS-c and Humanin genome which impacts their peptides with knock on effects on diabetes and cognitive decline. Professor Pinchas Cohen is the dean of the USC Leonard Davis School of Gerontology. He is a pioneer in the emerging science of mitochondria-derived peptides and their possible therapeutic benefits for diabetes, Alzheimer's and ot...
Nov 27, 2022•8 min•Season 20Ep. 3
In this episode Dr Cohen talks about mitochondria, the discovery of the peptides they create and some of the benefits that they provide. It seems that the micro-proteins are also not only restricted to the mitochondria and are also made in the nucleus. Professor Pinchas Cohen is the dean of the USC Leonard Davis School of Gerontology. He is a pioneer in the emerging science of mitochondria-derived peptides and their possible therapeutic benefits for diabetes, Alzheimer's and other diseases of ag...
Nov 23, 2022•10 min•Season 20Ep. 2
In this episode Dr Cohen talks about why he started studying aging, his views on IGF-1 and his theory of why we age. Professor Pinchas Cohen is the dean of the USC Leonard Davis School of Gerontology. He is a pioneer in the emerging science of mitochondria-derived peptides and their possible therapeutic benefits for diabetes, Alzheimer's and other diseases of aging, an area which remains the focus of his current research. Mitochondria-derived peptides in aging and healthspan https://pubmed.ncbi....
Nov 19, 2022•10 min•Season 20Ep. 1
In this episode Dr Katz talk about how the quality of our food has changed in the past and how the concerns of the younger generation may impact it in the future. Dr Katz was an early proponent of preventative medicine and is the founder and former president of the Yale-Griffin Prevention Research Center. As well as appearing on ABC News and Good Morning America he has written 13 books including The Truth About Food and How to eat. He is the founder and CEO of Diet ID a company that makes a tool...
Nov 14, 2022•10 min•Season 19Ep. 7
In this episode Dr Katz talks the company has formed and the tool that it has created with the aim of providing a quick and easy way to measure your diet quality and find steps to improve it. Dr Katz was an early proponent of preventative medicine and is the founder and former president of the Yale-Griffin Prevention Research Center. As well as appearing on ABC News and Good Morning America he has written 13 books including The Truth About Food and How to eat. He is the founder and CEO of Diet I...
Nov 10, 2022•13 min•Season 19Ep. 6
In this episode Dr Katz talks about his personal protocol for longevity and the reasons that he follows it. Dr Katz was an early proponent of preventative medicine and is the founder and former president of the Yale-Griffin Prevention Research Center. As well as appearing on ABC News and Good Morning America he has written 13 books including The Truth About Food and How to eat. He is the founder and CEO of Diet ID a company that makes a tool to help measure and manage diet. And with that let me ...
Nov 06, 2022•8 min•Season 19Ep. 5
In this episode Dr Katz talks about whether, even with a healthy whole food diet, we should also include supplements and what those should be. Dr Katz was an early proponent of preventative medicine and is the founder and former president of the Yale-Griffin Prevention Research Center. As well as appearing on ABC News and Good Morning America he has written 13 books including The Truth About Food and How to eat. He is the founder and CEO of Diet ID a company that makes a tool to help measure and...
Nov 03, 2022•8 min•Season 19Ep. 4
Dr Katz was an early proponent of preventative medicine and is the founder and former president of the Yale-Griffin Prevention Research Center. As well as appearing on ABC News and Good Morning America he has written 13 books including The Truth About Food and How to eat. He is the founder and CEO of Diet ID a company that makes a tool to help measure and manage diet. And with that let me start the interview. Dr Katz's home page https://davidkatzmd.com/ Diet ID https://www.dietid.com/ Dr Catheri...
Oct 29, 2022•10 min•Season 19Ep. 3
In this episode Dr Katz talks a specific study comparing a Mediterranean to a keto diet and also discusses diet study design and why so many are pre-decided. We also talk about calorie restriction and intermittent fasting. Dr Katz was an early proponent of preventative medicine and is the founder and former president of the Yale-Griffin Prevention Research Center. As well as appearing on ABC News and Good Morning America he has written 13 books including The Truth About Food and How to eat. He i...
Oct 27, 2022•10 min•Season 19Ep. 2
In this episode Dr Katz talks about his path to preventative medicine and how important it is. We then get into the number one modifiable cause of chronic diseases which is diet. Dr Katz was an early proponent of preventative medicine and is the founder and former president of the Yale-Griffin Prevention Research Center. As well as appearing on ABC News and Good Morning America he has written 13 books including The Truth About Food and How to eat. He is the founder and CEO of Diet ID a company t...
Oct 22, 2022•11 min•Season 19Ep. 1
In this episode Professor Furman shares his personal protocol to stay healthy and have low inflammation and talks about where the longevity industry is going and where he thinks it should put its focus. Dr. David Furman is the Director of the Stanford 1000 Immunomes Project, Chief of the Center for AI and Data Science of Aging at the Buck Institute for Research on Aging, and a Adjunct Investigator for The National Scientific and Research Council, Austral University, Buenos Aires, Argentina. Dr. ...
Oct 19, 2022•8 min•Season 18Ep. 6
Edifice Health aim not to only measure inflammatory age but to also to provide supplements and suggest actions to improve it. In this episode we talk about how these will be determined and some of the future direction. We also talk about the anti-inflammatory nature of caffeine. Dr. David Furman is the Director of the Stanford 1000 Immunomes Project, Chief of the Center for AI and Data Science of Aging at the Buck Institute for Research on Aging, and a Adjunct Investigator for The National Scien...
Oct 16, 2022•8 min•Season 18Ep. 5
In this episode Dr Furman discusses the Stanford 1000 immunome project, the company that he set up to commercialize the iAge test, Edifice Health and the test itself. Dr. David Furman is the Director of the Stanford 1000 Immunomes Project, Chief of the Center for AI and Data Science of Aging at the Buck Institute for Research on Aging, and a Adjunct Investigator for The National Scientific and Research Council, Austral University, Buenos Aires, Argentina. Dr. Furman received his Ph.D. (summa cum...
Oct 12, 2022•10 min•Season 18Ep. 4
In this episode Dr Furman discusses what are the chief components of that make up the iAge clock and how they differ from the markers of acute inflammation. In particular CXCL9 is the main element of the iAge clock while classic marker of inflammation such as CRP, IL-6, TNF-alpha do not appear at all. Dr. David Furman is the Director of the Stanford 1000 Immunomes Project, Chief of the Center for AI and Data Science of Aging at the Buck Institute for Research on Aging, and a Adjunct Investigator...
Oct 09, 2022•8 min•Season 18Ep. 3
Dr. David Furman is the Director of the Stanford 1000 Immunomes Project, Chief of the Center for AI and Data Science of Aging at the Buck Institute for Research on Aging, and a Adjunct Investigator for The National Scientific and Research Council, Austral University, Buenos Aires, Argentina. Dr. Furman received his Ph.D. (summa cum laude) from University of Buenos Aires, Argentina, for his work on the identification of factors produced by tumors that enable cancer cells to escape immune attack. ...
Oct 05, 2022•11 min•Season 18Ep. 2
In this episode Dr Furman discusses chronic inflammation and how it differs from acute inflammation. Dr. David Furman is the Director of the Stanford 1000 Immunomes Project, Chief of the Center for AI and Data Science of Aging at the Buck Institute for Research on Aging, and a Adjunct Investigator for The National Scientific and Research Council, Austral University, Buenos Aires, Argentina. Dr. Furman received his Ph.D. (summa cum laude) from University of Buenos Aires, Argentina, for his work o...
Oct 02, 2022•11 min•Season 18Ep. 1
In this episode Dr Kaufmann talks about her personal protocol, how many supplements she takes (52) and some of the more advanced therapies that she uses, such as exosomes. Sandra Kaufmann, is a cell biologist who for the last seven years has been the Chief of Pediatric Anesthesia at the Joe DiMaggio Children’s Hospital. She is also the founder of the Kaufmann Antiaging Institute and the author of the book The Kaufmann Protocol: Why We Age and How to Stop It. In the book she describes the mechani...
Sep 28, 2022•14 min•Season 17Ep. 6
In this episode Dr Kaufmann talks about supplements and eye drops for aging eyes, including carnosine eye drops which may be able to reverse long sight. Sandra Kaufmann, is a cell biologist who for the last seven years has been the Chief of Pediatric Anesthesia at the Joe DiMaggio Children’s Hospital. She is also the founder of the Kaufmann Antiaging Institute and the author of the book The Kaufmann Protocol: Why We Age and How to Stop It. In the book she describes the mechanisms of aging on a c...
Sep 25, 2022•4 min•Season 17Ep. 5
In this episode Dr Kaufmann talks about supplements, that can be used to address loss of hair and loss of hair colour, including Ecklonia Cava a supplement from Japanese seaweed. We also cover sarcopenia where the supplements are leucine, collagen, resveratrol or pterostilbene and a source of nicotinamide, such as NMN or NR. Sandra Kaufmann, is a cell biologist who for the last seven years has been the Chief of Pediatric Anesthesia at the Joe DiMaggio Children’s Hospital. She is also the founder...
Sep 21, 2022•6 min•Season 17Ep. 4
In this episode Dr Kaufmann talks about the her list of required supplements for those who are over 40. This has the 5 from her original book, Pterostilbene, Astaxanthin, Nicotinamide, Carnosine, Curcumin. To which she has now added Quercetin, Lactoferrin and Spermidine. We also discuss some of them in more detail, touching on rapamycin and delivery systems such as liposomes and nano micelles. Sandra Kaufmann, is a cell biologist who for the last seven years has been the Chief of Pediatric Anest...
Sep 18, 2022•12 min•Season 17Ep. 3
