Organoids are transforming the way we approach the drug discovery pipeline. In this Tech Blast episode, Ritwika Biswas, Product Scientist at Sino Biological (Beijing, China), explains why drug discovery needs new methods and how organoids can help. Find out the importance of growth factors in the development of organoids for drug discovery, the challenges associated with their use and the impact of organoid biobanks on the field in this 15-minute overview of the landscape of organoids in drug di...
Oct 24, 2022•17 min
In this Tech Blast episode, we discuss multiplex PCR methods, their challenges and advantages, and the tools being developed to advance multiplexing capabilities. Marco Bianchi, Product Manager at Bio-Rad Laboratories (CA, USA), provides an insight into what role multiplexing plays in research.
Oct 11, 2022•14 min
In this month's episode of Editor's Picks, we’ve got articles on magnetic synthetic cells, the synthesis of the most complete artificial microbiome yet and how a key protein in human fertilization was identified.
Sep 30, 2022•6 min
In this episode of the Talking Techniques podcast, we explore microbiomes and the techniques used to profile them. Get an overview of the different techniques’ working principles, their pros and cons and the different applications that they are best suited to. Providing an expert insight into this field is Annabelle Damerum, Microbiome R&D Scientist at Zymo Research. Annabelle reveals some key tips best practice when profiling the microbiome and details the importance of an emerging aspect o...
Sep 29, 2022•22 min
As the cell and gene therapy industry expands further into commercialization, researchers, developers and manufacturers are growing increasingly aware of the need for specialized ancillary materials in the production of therapeutics. High-quality ancillary materials are often neglected during the early stages of development due to perceived cost, but conversion at later stages of development can be prohibitive and detrimental to program success. In this podcast, in association with Sexton Biotec...
Sep 28, 2022•30 min
In this special episode of Talking Techniques, brought to you from the Federation of European Neuroscience Societies Forum (FENS; 9th–13th July 2022), an expert panel discuss their research into the relationship between the gut–brain axis and addiction. The panel features Benjamin Boutrel (Lausanne University Hospital; Switzerland), Lorenzo Leggio (NIH Intramural Research Program; MD, USA) and Nathalie Delzenne (University of Louvain; Louvain-la-Neuve, Belgium), who discuss their current researc...
Sep 28, 2022•30 min
In this Tech Blast episode, we discuss all things organoids with Ritwika Biswas, Product Specialist at Sino Biological US Inc (PA, USA). Ritwika provides an overview of what are organoids are, how reconbinant growths factors are utlized in their development, the benefits 3D organoid systems offer over 2D cell culture systems and the various applications organoids can be used for. Ritwika also explores the challenges that remain in organoid research and how these can be overcome, as well as what ...
Sep 20, 2022•13 min
Hello and welcome to today’s latest episode of OC Talks Podcast by Oncology Central. My name is Jade Parker, Senior Editor of Oncology Central, and I am joined by Volkmar Mϋller from University Medical Center Hamburg-Eppendorf in Germany. Today we are going to discuss HER2-positive breast cancer including the unmet needs of the disease, and our hopes for the future.
Sep 14, 2022•9 min
In this Tech Blast episode, BioTechniques' Digital Editor, Annie Coulson, discusses single domain antibodies with ProSci’s Andy Lee, Lead Scientist of the Single Domain Antibody Program, and David Eling, Director of Business Development. Andy and David describe what single domain antibodies (sdAbs) are, including their unique characteristics, such as their small size. They then go on to explore the applications of sdAbs, from increasing resolution in imaging studies, to developing antidotes for ...
Sep 13, 2022•16 min
In this Tech Blast episode, our Digital Editor Annie Coulson talks with Carlo Messina, Senior Director for Oncology in Global Development and Medical Affairs at Roche (Basel, Switzerland), about the use of comprehensive genomic profiling (CGP) in cancer research. CGP can obtain more information about a tumor from a smaller biospecimen compared with other genomic profiling techniques and gives oncologists more tools for treating patients. Carlo talks about the applications of CGP, including detec...
Sep 13, 2022•16 min
In this episode, supported by BrandTech, returning guest Rob Vries, CEO of HUB organoids (Utrecht, The Netherlands), fills us in on the advancement of 3D cell cultures and organoids over the last 2 years, starting off by documenting how the pandemic impacted their development and uptake. We also discuss how the recent FDA Modernization Act, removing the requirement for drug candidates to be tested on animals, has impacted the drive for improved models, the key techniques available to analyze the...
Aug 26, 2022•30 min
In this episode of Editor’s Picks, presented by guest-host Grace Tyrrell, learn about how the need for vaccine refrigeration could be on the way out, a new chemical approach that may aid in the fight against antibiotic resistance and the use of AI algorithms as a potential cure for drug-resistant epilepsy.
Aug 25, 2022•5 min
Welcome to OC talks, a podcast series exploring the latest advancements in oncology. I’m your host, Jade Parker, Oncology Central’s Senior Editor. In this episode, supported by Sengenics, we will be exploring the importance of autoantibodies in the development of cancer as well as how they can be used in the early detection of tumors. Joining me for this episode is Field Application Scientist Joseph Miseirvitch from Sengenics, a precision medicine company working to improve patient outcomes for ...
Aug 24, 2022•10 min
BZ PPD Spotlight Podcast: an interview with Cyrille Bonhomme by Taylor & Francis Group
Aug 17, 2022•19 min
In this episode of Talking Techniques, supported by Bio-Rad, we discuss a key component of many gene therapies: recombinant adeno-associated viruses (rAAVs) and their production. These viruses act as efficient, accurate delivery vesicles for the gene therapy’s plasmid. Speaking to Associate Director of Biopharma Product Marketing at Bio-Rad Laboratories, Mark White, we take a look the different expression systems used for their production and compare their advantages, before looking at some of t...
Aug 03, 2022•27 min
In this episode of Editor’s Picks, hosted by our Assistant Editor Aisha Al-Janabi, learn about recent concerns over the validity of a pivotal Alzheimer’s disease study, how researchers answered a question about the heart dating back to the 1600s and a laser-based diamond sensing technology that improves magnetoencephalography precision.
Jul 29, 2022•6 min
In many regions of the world, HPV and its association with cervical cancer is a well-known but rarely considered issue, after the rollout of the HPV vaccine in the late 2000s. However, while this rollout significantly impacted cervical cancer rates where it was implemented, it was not universal and in many areas of the world HPV induced cervical cancer remains a critical issue. Cervical cancer is the leading cause of death for people with a cervix living in poverty in low-resource regions and on...
Jul 28, 2022•17 min
Recently, the Alliance for Artificial Intelligence in Healthcare (AAIH) published "The Lifecycle of an AI System in Healthcare", a whitepaper defining what healthcare is and provides guidelines on implementing artificial intelligence (AI) and machine learning (ML) in this setting. In this episode of Talking Techniques, we speak with Oscar Rodriguez, a board member at AAIH and one of the authors of this whitepaper, to find out more about what the lifecycle of AI is, the importance of having guide...
Jul 20, 2022•30 min
Recently, the Alliance for Artificial Intelligence in Healthcare (AAIH) published "The Lifecycle of an AI System in Healthcare", a whitepaper defining what healthcare is and provides guidelines on implementing artificial intelligence (AI) and machine learning (ML) in this setting. In this episode of Talking Techniques, we speak with Oscar Rodriguez, a board member at AAIH and one of the authors of this whitepaper, to find out more about what the lifecycle of AI is, the importance of having guide...
Jul 08, 2022•30 min
Welcome to our newest podcast series, Editor's Picks, where we'll round up the latest life science news from BioTechniques. In this bitesize podcast, we've got everything from the history of cephalopods in neuroscience research to recent advancements against antibiotic-resistant bacteria.
Jul 01, 2022•4 min
Mitigation strategies for the biological matrix supply chain: an interview with Mark O'Dell by Taylor & Francis Group
Jun 29, 2022•4 min
In this episode, supported by Zymo Research, guest host Georgia Bickerton explores NGS data and how bioinformatic pipelines and workflows can be optimized to make NGS data more accessible. To do this she speaks with Jeffrey Bhasin, Director of Informatics at Zymo Research, who discusses the key issues of reproducibility in bioinformatics, the selection of methods available to analyze different datasets and to investigate different aspects of these data. Listen today to discover the techniques av...
Jun 08, 2022•16 min
ADA assay development: a podcast interview with Lynn Kamen by Taylor & Francis Group
Jun 06, 2022•9 min
The key diagnostic and prognostic information locked away in cell-free nucleic acids (cfNAs) has become increasingly accessible due to developments in genetic and epigenetic profiling techniques. These advances have engendered the rise of liquid biopsy techniques, which capture and analyze cfNAs from samples such as blood, saliva, urine and feces, in diagnostics and basic disease research. However, challenges remain in the detection and analysis of these nucleic acid fragments, in part due to th...
May 26, 2022•22 min
The key diagnostic and prognostic information locked away in cell-free nucleic acids (cfNAs) has become increasingly accessible due to developments in genetic and epigenetic profiling techniques. These advances have engendered the rise of liquid biopsy techniques, which capture and analyze cfNAs from samples such as blood, saliva, urine and feces, in diagnostics and basic disease research. However, challenges remain in the detection and analysis of these nucleic acid fragments, in part due to th...
May 23, 2022•22 min
In this Tech Blast episode, we discuss preclinical models of non-alcoholic fatty liver disease with Gareth Guenigault, Lead Scientist of Services at CN Bio (Cambridge, UK). Gareth provides an overview of non-alcoholic steatohepatitis (NASH) therapeutic landscape and explains how incorporating organ-on-a-chip models into drug discovery workflows can improve this landscape. Get Gareth’s expert insight into the field and discover how to develop liver-on-a-chip NASH models, tips for analyzing the re...
May 19, 2022•15 min
FON-2021-1277 OCTalks by Taylor & Francis Group
Apr 26, 2022•12 min
In this episode, we discuss recombinant proteins: what are they and what are they used for? BioTechniques Editor Tristan Free speaks to Amy Sheng, Technical Account Manager at Sino Biological, who explains the history of recombinant proteins and how protein modeling techniques such as AlphaFold are changing their development. Find out how monoclonal antibodies have been used through the COVID-19 pandemic and how we may overcome challenges in production, upscaling and more in this episode of Talk...
Apr 19, 2022•18 min
In this Tech Blast episode, we discuss generating, standardizing and sharing microbiome data with Raul Cano, Chief Scientific Officer at The BioCollective. Raul provides a brief overview of the reproducibility crisis and explores how the use of standards and databases can address the challenges it poses. Get Raul’s insight into the field and discover the steps that can be taken to make microbiome research accessible and reproducible. Contents: Introduction: 00:00–00:40 Overview of the reproducib...
Apr 19, 2022•12 min
In this '3D and tea' interview, we speak to Dolores Serrano and Katerina Lalatsa all about the potential of utilizing 3D printing in cancer studies.
Apr 12, 2022•24 min
