As generative AI tools improve, it is becoming easier to digitally manipulate content and harder to tell when it has been tampered with. Today we are talking to someone on the front lines of this battle. Ali Shahriyari is the co-founder and CTO of Reality Defender. Ali's problem is this: How do you build a set of models to distinguish between reality and AI-generated deepfakes? See omnystudio.com/listener for privacy information.
Aluminum is the most abundant metal in the Earth’s crust. It’s cheap, ubiquitous, and surprisingly energy dense. Peter Godart is the co-founder and CEO of Found Energy. Peter's problem is this: How can you use aluminum as a source of clean, renewable energy? See omnystudio.com/listener for privacy information.
Sarah Rudd is the co-founder and CEO of the soccer analytics company src | ftbl (It’s pronounced “Source Football.”) Sarah’s problem is this: How do you model a sport as fluid and complex as soccer and translate the analytical insights from the model into meaningful changes on the pitch? This is the third and final episode of our series about people who are working at the frontiers of technology to help elite athletes perform better. See omnystudio.com/listener for privacy information....
Jimmy Buffi is the CEO and co-founder of Reboot Motion, which uses biomechanics to help athletes in Major League Baseball and the NBA. Jimmy's problem is this: How do you turn data about how professional athletes move into knowledge that helps them perform better? This is the second episode of our series about people who are working at the frontiers of technology to help elite athletes perform better. Music: Let's Have Some Fruit (The Fruit Song) by J Buffi See omnystudio.com/listener for privac...
On the next few episodes of What's Your Problem, Jacob Goldstein is talking with people working at the frontiers of technology to help elite athletes perform better. Today’s guest is Silvia Blemker, a professor of biomedical engineering at the University of Virginia and the co-founder of Springbok Analytics. Silvia's problem is this: How do you combine MRI scans and artificial intelligence to generate new insights that can help both elite athletes and people suffering from diseases that affect t...
Laura Niklason is the co-founder and CEO of Humacyte. Laura's problem is this: How can you use human cells to create blood vessels that surgeons can pull out of a bag and implant into patients? Although still awaiting FDA approval in the U.S., Humacyte's vessels have already been used to treat wounded soldiers in Ukraine. See omnystudio.com/listener for privacy information.
As demand for clean energy grows, engineers around the U.S. are working on a new generation of nuclear reactors. These designs reflect how nuclear energy could fit into the power grid – and our lives – in new ways. Yasir Arafat is the Chief Technology Officer at Aalo Atomics. Yasir’s problem is this: How do you mass produce nuclear reactors that are safe, scalable, and cheap? See omnystudio.com/listener for privacy information.
This week on Risky Business, Nate and Maria discuss whether Supreme Court Justice Sonia Sotomayor should retire, the perils of sports betting among professional athletes, and what the return of Roaring Kitty means for traditional market analysis. Further Reading: “Sonia Sotomayor Should Retire Now” from The Atlantic “Should Sonia Sotomayor Retire?” from Slate “MLB bans Padres’ Tucupita Marcano permanently for betting on baseball” from the NYT “Lifetime bans and careers in tatters – recent sports...
Tim Harford is joined by Jacob Goldstein to answer your questions. Does winning the lottery make you unhappy? Is Bitcoin bad for the economy? When does correlation imply causation? And what will Tim and Jacob do when the robot overlords come for their jobs? Enjoy this episode from Cautionary Tales, another Pushkin podcast. See omnystudio.com/listener for privacy information.
Palm oil is a cheap and remarkably versatile vegetable oil. It’s in a ton of products, from food to cosmetics, detergent, and chewing gum. But producing so much palm oil is really bad for the planet. Shara Ticku is the co-founder and CEO of C16 Biosciences. Shara's problem is this: Can you get yeast to make an oil that is just as useful as palm oil – without clearing land to grow palm trees? See omnystudio.com/listener for privacy information....
Last year, the FDA approved a treatment for sickle cell disease using a revolutionary new gene editing technology called CRISPR. Rachel Haurwitz conducted pioneering research on CRISPR as a graduate student. Now she’s the co-founder and CEO of Caribou Biosciences. Rachel's problem is this: How can you improve CRISPR and use it to engineer human immune cells to fight cancer? See omnystudio.com/listener for privacy information.
Robert Langer has co-founded dozens of companies, holds over a thousand patents, and is a pioneering figure in drug delivery and tissue engineering. Robert has solved a lot of problems, and is working on many more with his lab at MIT. But there is one big problem that has stuck with Robert his whole career: How do you get discoveries out of the lab and into the world? See omnystudio.com/listener for privacy information.
Mateo Jaramillo is the co-founder and CEO of Form Energy. Mateo’s problem is this: How do you build batteries that can provide affordable backup power to the grid for days at a time? As it turns out, the basic technology was developed – and then mostly ignored – over 50 years ago. See omnystudio.com/listener for privacy information.
This March, doctors successfully transplanted a pig kidney into a person for the first time in history. Mike Curtis is the CEO of eGenesis, the company that raised the pig whose kidney was used for the procedure. Mike's problem is this: How do you genetically engineer pigs to provide organs – kidneys, hearts, livers – for people? See omnystudio.com/listener for privacy information.
Imagine picking up your phone and ordering something from Walmart. Fifteen minutes later, a drone hovers over your yard, lowers your order down to you, and zips away. Adam Woodworth wants this to be so boring you don't even notice. He’s the CEO of Wing, a drone delivery company. His problem is this: How do you turn a flashy idea like a delivery drone into something as ubiquitous as a shopping cart? See omnystudio.com/listener for privacy information....
Psychedelics are going mainstream. The FDA has approved ketamine for certain patients with depression, and may soon approve MDMA for post-traumatic stress disorder (PTSD). But a fundamental question remains unclear: How do psychedelics work? Gul Dolen is a professor of psychology and neuroscience at UC Berkeley. In a series of experiments, Gul has found evidence of a common mechanism that a wide range of psychedelics use to affect the brain. If Gul is correct, these drugs may be useful not only ...
Kai Marshland is the co-founder and chief product officer at WindBorne Systems. Kai's problem is this: How do you build weather balloons that can stay in the air for months at a time, and pair the data gathered by the balloons with AI to make weather forecasts that are way better than anything we have today? See omnystudio.com/listener for privacy information.
Jonathan Hurst is a professor at Oregon State University, and co-founder and chief robot officer at Agility Robotics. Jonathan's problem is this: How do you design a robot that can walk and do useful tasks that companies will pay for? The solution begins with trying to understand how birds walk. See omnystudio.com/listener for privacy information.
What does sickness sound like? Sometimes it’s obvious, like a cough, sniffle, or stuffy nose. But some conditions cause subtle changes that only a trained ear – or AI – can detect. Dr. Yael Bensoussan is a professor of otolaryngology and the director of the Health Voice Center at the University of South Florida. Her problem is this: How do you build a giant, public database of thousands of voice recordings, and use it to train AI tools that can hear when people are getting sick? See omnystudio.c...
Cement is, almost literally, everywhere. It is extraordinarily useful, which is why humanity makes 4 billion metric tons of it every year. But cement is also extremely carbon intensive to produce. Leah Ellis is the co-founder and CEO of Sublime Systems. Her problem is this: How can you make cement, at scale, without emitting carbon dioxide? See omnystudio.com/listener for privacy information.
Sam D'Amico is the founder and CEO of Impulse Labs, a company that makes induction stoves, with a clever twist. Sam’s problem is this: How do you build an electric cooktop that works just as well as gas, and can be installed without having to rewire the house? The solution that Sam found could eventually help transform not only kitchens, but the way homes draw power from the electrical grid. See omnystudio.com/listener for privacy information....
Tim Ellis is the co-founder and CEO of Relativity Space, a company with a unique approach to manufacturing rockets. Tim’s problem is this: How can you use 3D printing to make rockets more efficiently? Eventually, Tim wants to send a rocket – and printer – to Mars to build the first Martian industrial base. See omnystudio.com/listener for privacy information.
Every year in the U.S., tens of thousands of hospital patients die of preventable causes. For many of these patients, warning signs are subtle and easy for doctors to miss. Suchi Saria is the founder and CEO of Bayesian Health, and a professor at Johns Hopkins where she runs a lab focused on machine learning and healthcare. Suchi’s problem is this: How can you use AI to detect when hospital patients are at risk of potentially deadly complications – and how can you get doctors to listen? See omny...
Gia Schneider is the co-founder and CEO of Natel Energy, a company that is trying to transform the way hydroelectric power works. Gia’s problem is this: how do you draw hydropower from rivers without damaging the ecosystem? As it turns out, we have a lot to learn from nature’s furriest engineers – beavers. See omnystudio.com/listener for privacy information.
Peter Chen is the co-founder and CEO of Covariant. Peter’s problem is this: How do you take the AI breakthroughs of the past decade or so, and make them work in robots? Peter was one of the first employees at OpenAI, the maker of ChatGPT. On the show, he talks about how AI has evolved, and why it's so difficult to teach a robot to fold a towel. See omnystudio.com/listener for privacy information.
Fei-Fei Li is a Stanford computer scientist and the former chief scientist of artificial intelligence/machine learning at Google Cloud. When Li entered the field of AI in the 2000s, researchers were making slow progress, optimizing algorithms to incrementally improve outcomes. Li saw that the problem wasn’t the algorithm, but the size of the datasets being used. So she built a massive database of images called ImageNet. It was a huge breakthrough, and helped lead the emergence of modern AI. See ...
Tim Latimer is the CEO and co-founder of Fervo Energy, a company that is using a new approach to produce carbon-free geothermal energy. Tim and his company are drawing on innovations from the oil and gas industry to expand geothermal energy production to new places like the Utah desert, and maybe one day, to Mars. See omnystudio.com/listener for privacy information.
Manolis Kellis is a professor of Computer Science at the Massachusetts Institute of Technology. He works in computational biology, taking giant datasets relating to genetics and health outcomes and tries to understand what’s going on. Manolis’ research focuses on genomics, and a related field called epigenomics. Manolis’ problem is this: What are the cellular mechanisms of a disease? And how can we intervene to keep people healthy? See omnystudio.com/listener for privacy information....
After working as a chef for decades, Anthony Strong’s dream came true: He opened his own restaurant. His problem was a classic one: Restaurants are bad businesses. So he set out to open a new kind of restaurant, with a new business model. In this episode, he tells us about how he accomplished that with his latest venture, Pasta Supply Co. in San Francisco. See omnystudio.com/listener for privacy information.
Selling hydrogen to make fertilizer is a huge business. It also drives tons of carbon emissions. Rob Hanson, the co-founder and CEO of a company called Monolith is trying to create hydrogen without emissions -- and to do it at scale, at a competitive price. A key tool he’s using: The biggest plasma torch ever built. See omnystudio.com/listener for privacy information.
