The latest IPCC assessment raised alarm about the rate at which manmade emissions are contributing to climate change. Much of the focus for action is on reducing levels of carbon dioxide, however there is a more potent greenhouse gas, methane, produced by natural and industrial processes which, as Roland Pease tells Drew Shindell of Duke University and lead author on the Global Methane Assessment, is relatively easy to target for reduction. Gut microbes and behaviour Roland speaks to neuroscient...
Aug 15, 2021•1 hr 8 min
July 2021 saw temperatures in the western US and Canada smash previous records by 5 degrees. And that’s what we should expect, according to a study prepared much earlier but published, coincidentally, just a few days later. A hallmark of rapid climate change, says author Erich Fischer of ETH Zurich, will be an accelerating number of record-shattering, and socially disruptive, events. A large new study on communications and hierarchy across a large range of our ape and monkey relatives has just b...
Aug 08, 2021•1 hr 5 min
The Natural History Museum in London holds a massive collection of insects. It asked researchers at the Diamond light source, a facility near Oxford, to develop a high throughput X-ray microscope to take 3D scans of them all. Roland Pease has been to see the new technology in action. Many people seeking compensation for the impacts of climate change are turning to the law courts. Successes so far have been few. Oxford University’s Friederike Otto, who specialises in connecting weather extremes t...
Jul 04, 2021•1 hr 10 min
The latest Nyiragongo eruption was not entirely unexpected, the volcano’s lava lake inside the crater had been building up for years. Local volcanologists say it was only a matter of time before an eruption occurred. The big concern was where the flank of the volcano would be breached as the city of Goma rests under the volcano and there are potential fissures even within the town. However there are still questions over the effectiveness of seismic monitoring in the area, North Kivu. The Goma ob...
May 29, 2021•55 min
A brain-computer interface allows a severely paralysed patient not only to move and use a robotic arm, but also to feel the sensations as the mechanical hand clasps objects . We hear from Jennifer Collinger at Pittsburgh University’s Rehab Neural Engineering Labs. And Nathan Copeland, who has been controlling the robotic arm with his thoughts via a series of brain implants. Ralph Baric of the University of North Carolina tells us about the development of a multi-component vaccine that would be e...
May 23, 2021•1 hr 12 min
We wouldn’t drink dirty water so why do we put up with polluted air? Researchers are calling for a major rethink on our attitude to air quality. Professor Lidia Morawska, from the Queensland University of Technology, says attention to air quality during the Covid pandemic has shown how levels of airborne disease can be reduced. Sam Wilson from the UK Medical Research Council, University of Glasgow Centre for Virus Research has been investigating genetic mechanisms associated with susceptibility ...
May 16, 2021•1 hr
Analysis of the 78,0000-year-old fossil of a Kenyan boy reveals he was likely buried with care and attention, the body wrapped and laid to rest supported on a pillow. Maria Martinon-Torres, of the National Research Centre on Human Evolution in Burgos, Spain, and a team from Kenya and Germany used techniques from paleontology and forensic science to reveal his story from the fragile remains. A promising malaria vaccine is to enter trials which could lead to it being used globally to vaccinate chi...
May 09, 2021•1 hr 6 min
One of our most complete ancient ancestor’s fossils has been transported to the UK from South Africa in order to be scanned at the Diamond Light Source. Roland Pease investigates what these scans could reveal about the human story. Professor Corinne Le Quéré explains how she managed to look past the 7% reduction in human emissions caused by the pandemic in 2020 to reveal the impact of the Paris Climate agreements, and explains what more needs to be done. Roland speaks with anthropologist Dr. Rol...
Mar 07, 2021•54 min
Although vaccines will go a long way to reducing the number of cases of Covid, there’s still a need for other approaches. One of these could be an engineered biomolecule, designed by virologists Anne Moscona and Matteo Porotto, that blocks SARS-CoV-2 precisely at the moment it tries to enter cells in the nose and upper airways. Roland Pease talks to Anne Moscona about this “molecular mask”. We’re already beginning to see really encouraging analyses showing that Covid vaccines are performing as w...
Feb 28, 2021•1 hr 10 min
A paper in the BMJ shows that deaths from Covid 9 are being massively overlooked in Zambia. The new data come from post-mortem tests at the University Hospital mortuary in Lusaka, showing that at least 1 in 6 deaths there are due to the coronavirus; many of the victims had also been suffering from tuberculosis. Chris Gill of Boston University’s Department of Global Health, and Lawrence Mwananyanda, chief scientific officer of Right to Care, Zambia, discuss their findings with Roland Pease. New v...
Feb 21, 2021•1 hr 6 min
On 18th February the Perseverance rover should land on Mars. Katie Stack-Morgan of NASA’s Jet Propulsion Lab tells Roland Pease about the technological advances that mean that the spacecraft should be able to land in Jezero Crater. Imperial College geologist Sanjeev Gupta discusses what this crater can reveal about the history of life on the red planet. After months of negotiations, and weeks of work on the ground, a team brought together by the World Health Organisation has just concluded its f...
Feb 14, 2021•1 hr 13 min
A new trial is about to start in the UK, seeing if different vaccines can be mixed and matched in a two-dose schedule, and whether the timing matters. Governments want to know the answer as vaccines are in short supply. Oxford University’s Matthew Snape takes Roland Pease through the thinking. Despite the numbers of vaccines being approved for use we still need treatments for Covid-19. A team at the University of North Carolina is upgrading the kind of manufactured antibodies that have been used...
Feb 07, 2021•1 hr 10 min
Northern white rhinos are extinct in the wild and there are just two females in captivity in Kenya. Conservationists are working on an artificial breeding programme, using eggs from the females and sperm from a deceased male. Now five embryos have been created. Thomas Hildebrandt of the Leibniz Institute for Zoo and Wildlife Research in Berlin explained the research. President Biden’s first executive order was what’s being called the hundred-day mask mandate. The day before the inauguration a ma...
Jan 24, 2021•1 hr 2 min
After collecting data for more than twelve years the North American Nanohertz Observatory for Gravitational Waves (NANOGrav) announced it may have detected new kinds of gravitational waves caused by colliding supermassive black holes. Professor Chiara Mingarelli of the University of Connecticut tells Roland Pease why this is such an exciting discovery. Supermassive black holes are at the heart of galaxies and they are the engines of quasars, the brightest light sources in the heavens that can be...
Jan 17, 2021•1 hr 3 min
Mutant strains of SARS-Cov2 have been identified not only in the UK, where it was first identified, but also in at least 30 other countries. And to complicate matters, another alarming variant, with some similar mutations, has arisen in South Africa. Roland Pease talks to Ravi Gupta, a virologist at Cambridge University and Tulio de Oliveira of the University of KwaZulu Natal about these new strains. There’s only so much that can be learned about the virus by looking at the patients it infects. ...
Jan 10, 2021•54 min
This has been an incredible year for scientific advance and collaboration, epitomised by the roll out of vaccines that didn’t exist a year ago, against a virus that no one had ever heard of . And yet at the same time its been a year of incredible frustration. We are stil largely using the same methods to counter the virus that were used in past pandemics, going back a hundred years. Here we look back at key the findings on who is most susceptible and why, and ask how to improve the strategies fo...
Jan 03, 2021•53 min
In our first programme of the year, we gathered a group of scientific experts directly involved in analysing the structure and impact of the SARS- Cov-2 coronavirus. There were concerns over the emergence of two new variants, Alfa and Beta, especially whether these variants might spread more quickly or outmanoeuvre the suite of new vaccines that were about to be rolled out. And now with Omicron, the same questions are being asked about this variant’s ability to spread and overcome our defences. ...
Jan 02, 2021•1 hr 8 min
It was the end of December 2019 when reports of a new flu like infection first came out of China. Within weeks millions of people were in lockdown as the virus took hold around the world. In this programme we look back and revisit the scientists who were ready, those who had been studying bat coronaviruses and warning of their pandemic potential. The scientific response was immediate. The coronavirus tests now used across the world were being developed within a few hours of news of the outbreak ...
Dec 27, 2020•54 min
This week the UK Health secretary raised concerns over a new variant of SARS- CoV-2 currently spreading across Europe. Viruses mutate all the time so it’s no surprise that a new form of the one causing Covid -19 would emerge. However, virologist Ravi Gupta who analysed the new strain says we need to be weary in case future strains mutate in ways that could overcome vaccines. Immunologist Akiko Iwasaki is part of a team looking at the impact of Covid -19 on our immune system. Her research has unc...
Dec 20, 2020•1 hr 8 min
Pictures of coffins and mass graves seen by satellites showed that Manaus has been badly affected by Covid- 19. Now analysis of blood samples shows the extent to which the virus took hold in the Amazon city earlier this year. Investigators Ester Sabino and Lewis Buss from Brazil’s University of Sao Paulo discuss how and why the virus spread. Humanity has been modifying the environment for millennia, but have we now reached a point where it’s all too much? An analysis by Emily Elhacham from Tel A...
Dec 13, 2020•56 min
This year’s Atlantic hurricane season has seen a new record for severe storms says Climatologist Michael Mann. He says warming oceans are one of the drivers. And Australia has seen spring temperatures hit new highs. Climate scientist Sarah Perkins – Kirkpatrick says it’s all the more remarkable as weather patterns are currently in a cycle associated with cooler temperatures. Where exactly did SARS- COV-2 emerge from? That’s one of the questions for a WHO fact-finding mission to China looking int...
Dec 08, 2020•1 hr 7 min
While developing new treatments drug companies usually release little useful information on how the clinical trials are progressing. However with the world’s attention on potential vaccines against Covid -19, the usually dull data on the progression of each trial step is subject to huge scrutiny. It doesn’t help to clarify things says epidemiologist Nicole Basta when that data raises questions about the rigour of the trial itself. This seems to be what happened with the latest Astra Zeneca, and ...
Nov 29, 2020•1 hr 4 min
Tests on patients for up to 8 months following their infection with SARS- CoV-2 suggests an immune response can persist. Alessandro Sette and Daniela Weiskopf at the La Jolla Institute in California are optimistic this could mean vaccines would also confer long lasting immunity. An analysis of samples from Kenya’s blood banks by Sophie Uyoga at the KEMRI-Wellcome Research Programme reveals far more people in Kenya contracted the virus than was previously know. The figures mean Kenya has similar ...
Nov 22, 2020•1 hr 4 min
The WHO is working with China to try and pinpoint the source of SARS- COV-2. Sian Griffiths, Emeritus Professor of Public Health at the Chinese University of Hong Kong says there are lessons we can learn from the investigation she led into the original SARS outbreak back in 2003. That inquiry revealed how SARS had spread from bats to humans via civet cats. A Covid-19 vaccine claims to be 90% effective. It uses genetic material, messenger RNA. Daniel Anderson of Harvard MIT Health Science tells u...
Nov 15, 2020•1 hr 6 min
All the farmed mink in Denmark are to be killed. Around 17 million. This is because they have SARS COV-2 coronavirus circulating among them and some humans have contracted a new strain from the animals. The scientific detail is sketchy, but Emma Hodcroft at Basel University pieces together a picture of what this means for tackling the virus. Typhoon Goni and hurricane Eta are two very powerful tropical cyclones. But the way these storms are recorded differs by geographical location and recording...
Nov 08, 2020•59 min
Last week NASA’s Osiris-Rex mission successfully touched down on asteroid Bennu’s crumbly surface. But the spacecraft collected so much material that the canister wouldn’t close. NASA systems engineer Estelle Church tells Roland Pease how she and the team back on Earth performed clever manoeuvres to remotely successfully shut the lid. As winter draws on in the North, and people spend more time indoors, there’s considerable debate about the conditions in which SARS-Cov2 is more likely to spread. ...
Nov 01, 2020•1 hr 4 min
Science in Action talks to Nasa researcher Hannah Kaplan who is part of the team for the space agency’s sampling mission to the asteroid Bennu. Mission scientists were overjoyed this week when the probe Osiris Rex momentarily touched the asteroid and sucked up some of the sand and grit on its surface. What might we learn when the sample is returned to Earth in three years' time? There is some not-such-good news about a theory about immunity to the pandemic coronavirus, and medical researchers in...
Oct 25, 2020•1 hr 1 min
Why is there such a range in the number of deaths from Covid -19 between countries? A study of the data across 21 industrialised countries reveals a wide discrepancy. Preparedness and the point at which countries went into lockdown were key factors says Epidemiologist Jonny Pearson- Stuttard Recurring illnesses which show up sometimes months after a Covid -19 infections are being more commonly reported. The Uk’s National Institute for Health research has launched a major initiative to better und...
Oct 18, 2020•1 hr 8 min
Data from clinical investigations has suggested that a specific mutation in the SARS-Cov -2 virus has made it more transmissible. This finding is now supported by molecular biology work. Ralph Baric from the University of North Carolina led a team comparing the form of the virus which first emerged from China with the mutated type now prevalent word wide. Bats are known to carry many different types of viruses, horseshow bats specifically carry coronaviruses, apparently without any ill effects t...
Oct 11, 2020•1 hr 11 min
An analysis of Covid-19 data from South India shows children more than any other group are transmitting the virus both to other children and adults, Epidemiologist Ramanan Laxminarayan tell us the data also shows the situations in which the virus is most likely to spread, public transport is of particular concern. The WHO has launched an initiative to roll out rapid testing, particularly to countries that don’t have access to lab based tests, Catharina Boehme who leads one of the WHO’s partner o...
Oct 04, 2020•1 hr 11 min
