The objective of this dissertation was to depict the structural parallels and differences of veterinary education in Germany and Great Britain from the point of view of the general framework as outlined by the European Commission. One of the main differences was the definition of the occupational area of veterinary surgeons and therefore the objectives of veterinary training. While the veterinary occupational image in Great Britain targeted to animal health care, the occupational image of veteri...
Jul 18, 20030
Thioredoxin Reductases (TR) are ubiquitously expressed Selenium-containing redox enzymes. By reducing different intracellular substrates they protect cells from oxidative stress. For mus musculus two members of the Thioredoxin Reductase gene family have been characterized so far: TR1 and TR2. Whereas the subcellular localization of TR1 is mainly cytoplasmatic, TR2 was only found in mitochondria. The protein functions of TR1 and TR2 were investigated by examining genetically engineered mice. Here...
Jul 18, 20030
Neisseria meningitidis, ein Gram negatives pathogenes Bakterium ist eine der Ursachen für schwere Septikämie und Meningokokkenmeningitis. Nach Besiedelung des menschlichen Nasopharynx und Übertritt in die Blutbahn besteht ein zentraler Schritt in der Pathogenese der durch N. meningitidis verursachten bakteriellen Meningitis in der Interaktion der Bakterien mit Zellen der Blut-Hirn-Schranke. Die Schwere der Erkrankung scheint direkt mit der Produktion proinflammatorischer Zytokine, Chemokine und ...
Jul 18, 20030
Yersinia enterocolitica of bioserovar 4/O:3 is the most common pathogenic type found in pigs and pork including edible offal in Southern Germany. Limited epidemiological data is available of human Y. enterocolitica infections in Bayern. The sources and transmission routes of yersiniosis are not clear. This work was conducted to get more information on the epidemiology in Munich area. In the first part of this work, the human strains were isolated from faecal samples of patients with diarrhoea du...
Jul 18, 20030
Experimental investigations at the porcine over-sized coronary stent-model for in-stent-restenosis rate after implantation of uncoated niob-zirkonium stents and niob-zirkonium stents coated with iridiumoxide. Background: The treatment of atherosclerotic stenosis in coronary artery disease with balloon expandable coronary stents has been successfully practised in minimal invasive cardiology in the last two decades. Today almost all commercially coronary stents are made of stainless steel (316L) a...
Jul 18, 20030
Ermittlung von Referenzbereichen für zelluläre Blutbestandteile beim geschlachteten Fleckviehmaststier Im Rahmen der vorliegenden Arbeit sollten Referenzbereiche für zelluläre Blutbestandteile beim geschlachteten Fleckviehmaststier ermittelt werden. Die Untersuchungen wurden an 514 Mastbullen der Rasse Deutsches Fleckvieh im Rahmen des Schlachtvorganges am Schlachthof München durchgeführt. Von den Probanden, die lediglich einer Lebendbeschau unterzogen wurden, wurde nach Bolzenschußbetäubung und...
Jul 18, 20030
The aim of these examinations was to check various flow cytometric methods to establish whether they are suitable objective methods for assessing the quality of cryopreserved sperm from stallions. The plasma membrane integrity, the mitochondrial membrane potential, the acrosomal status and the integrity of the chromatin structure in cryopreserved sperm from stallions were assessed. For this purpose various fluorescent stainings were carried out both immediately after the semen samples were thawe...
Jul 18, 20030
A total of 1248 animals was stunned in two EU approved slaughterhouses using either cartridge activated or pneumatic concussion stunning devices. In total, 12 % of the animals had to be stunned twice. If the shooting position deviated from the midline the rate of re-stunning increased considerably. In the main experiment carried out in the larger of the two slaughterhouses 67.8 % of the animals lay without any movement immediately after falling out of the stunning box. Pathological examinations ...
Jul 18, 20030
In the present study an efficient procedure for detecting salmonellas in feces of tortoises should be established. First of all a survey of occurrence of salmonellas in reptiles and their importance for reptiles as well as for man is given. Next an appropriate incubation temperature for multiplying salmonellas of reptilian origin in a selective enrichment medium was evaluated. Furthermore 86 salmonella strains isolated from reptiles were tested on nine different selec-tive solid media for their ...
Jul 18, 20030
In the present study the data of 156 calves of different breeds, aged two to twelve weeks, with neonatal diarrhoea were evaluated retrospectively. The calves were in-patients in the II. Medizinischen Tierklinik of the LMU München in 1997 and 1999, where the necessary data were collected. The aim of this study was to find out, how certain easily obtainable findings change with the severity of the disease. This was conducted with the results of the macroscopic (colour, grade of cloudiness and poll...
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This paper describes the development and application of enzyme immunoassays for the detection of antimicrobials in milk, aiming at the establishment of a biosensor system for the on-line analysis of drug residues in milk. For the development of group-specific antibodies against penicillins rabbits were immunized with an ampicillin-BSA-conjugate. The resulting antiserum was employed for the development of a direct competitive enzyme immunoassay (EIA), giving a detection limit of 1 ng/ml for penic...
Jul 18, 20030
The forces in the limb joints in the dog were investigated for the first time in the German Shepherd. The main focus lay on the joints of the forelimb, as these have been hardly investigated so far. But also the joint forces of the joints of the hind limb were demonstrated. Additionally the foundations for a forward dynamic model were developed for the forelimb. The study constitutes two parts. The aim of the first part was to develop the foundations for a forward dynamic model. For that reason ...
Jul 18, 20030
Pharmacologically enhanced manual semen collection and computer assisted sperm head morphometry in the white rhinoceros (Ceratotherium simum) In this study the influence and applicability of pharmacologically enhanced semen collection in the white rhinoceros (Ceratotherium simum) was investigated. Obtained semen samples were assessed by routine methods. Additionally, computer assisted sperm head dimensions were determined for 15 individuals and a morphometric analysis was performed. A combinatio...
Jul 18, 20030
Bone integration and biocompatibility of a new bioresorbable polymer for screw augmentation in the osteosynthesis of osteoporotic cancellous bone: The surgical treatment of an osteoporosis-associated fracture is a clinically relevant problem, which yet has no satisfactory solution. The fixation of conventional implants is limited because of the reduced bone density in osteoporotic bones. To ensure stable fixation compound osteosynthesis has been used since the 1950s. Polymethylmethacrylate (PMMA...
Jul 18, 20030
This study describes the process of implementing a quality assurance system in a middleclass bakery and discusses its impact. After a thoroughly planned assessment of the situation an HACCP-System was developed, which included a substantial catalogue of measures with short, medium and long term procedures. The purpose is to align the bakery’s procedures with the hygiene regulations of the LMHV. During the assemblage of the catalogue of measures, it was noted that even basic hygiene needs improve...
Jul 18, 20030
Aetiology, signs and prognosis of male cattle with urethral occlusion The objective of this prospective study was a detailed description of the clinical signs of cattle with urethral occlusion and to define prognostic indicators. Male cattle admitted to the clinic were included in the study if their history or initial clinical examination suggested urethral occlusion. A total of 126 cattle one month to two years old were enrolled. For the description of the clinical picture the relevant anamnest...
Jul 18, 20030
Viral agents isolated from 18 snakes (families Colubridae, Viperidae, and Crotalidae) showing respiratory symptoms and neuronal diseases were investigated. Identifying the isolates as paramyxoviruses showing characteristic cytopathic effect, was carried out by electronmicroscopy and RNA-PCR of two partial genes (L and F). After sequencing RNA-PCR amplicons, identical sequences were found for the reptilian paramyxoviruses (RPMV) isolated in the same outbreak from different snake species, suggesti...
Jul 18, 20030
We describe the isolation and characterization of an iridescent virus from commercially produced colonies of Gryllus bimaculatus in Germany, which showed apparent mortality. Transmission electron microscopy studies on adult cricket specimens revealed the paracrystalline assembly of icosahedral virus particles in the cytoplasm of hypertrophied abdominal fat body cells. The infecting agent could be cultivated in the lepidopteran cell line sf-9, where it caused cytopathogenic effects such as cell h...
Jul 18, 20030
Caliciviren sind kleine, unbehüllte Viren mit einem RNA-Genom positiver Polarität. Die Vertreter der Familie Caliciviridae sind Erreger wichtiger, zum Teil sehr unterschiedlicher Erkrankungen bei Mensch und Tier. Das Feline Calicivirus (FCV) gilt als einer der Haupterreger des Katzenschnupfenkomplexes. Das FCV ist für Replikationsstudien an Caliciviren besonders gut geeignet, da es sich effizient in Zellkultursystemen vermehrt. Da der Replikationszyklus nur zum Teil aufgeklärt ist, wurden in der...
Jul 18, 20030
Insulin-like growth factors (IGF-I and IGF-II) are expressed in many cell types and tissues and act in endocrine, autocrine or paracrine manner to regulate cellular proliferation, survival and differentiation. IGF actions are initiated upon binding to the type I IGF receptor (IGF-IR) and are modulated through interactions with a family of six secreted IGF-binding proteins (IGFBP-1 to -6). Although the six conserved IGFBPs are structurally related, each of them has specific characteristics and ma...
Jul 18, 20030
Studies on the genetic variability of recent isolates of porcine parvovirus The aim of this study was to review the antigenetic variability of porcine parvovirus and to examine the role of porcine parvovirus in reproductive failure. Organ specimens of 500 fetuses and stillborn piglets from a total of 172 farms were analysed. Total DNA was isolated from the explants and quantitative as well as qualitative PCR was subsequently carried out. In 82 samples (15,8%) out of 28 farms (16,3%), PPV was dia...
Jul 18, 20030
About the occurrence of Transmissible Spongiform Encephalopathies and bacterial CNS infections in roe deer, red deer and chamois in Bavaria Brain samples of 849 wild ruminants (654 roe deer, 189 red deer and 6 chamois) from Bavaria were examined for the occurrence of TSE and encephalopathies caused by bacteria, respectively. For this, the following investigations were carried out: • General bacteriological investigation (aerobic incubation on blood, standard I nutrient and Gassner Agar) • Detect...
Jul 18, 20030
The aim of this work was the evaluation of literature about physiology of reproduction, assisted reproduction technologies and associated biotechniques in domestic dogs (Canis familiaris). In the bitch preovulatory follicular luteinization results in exposure of oocytes to increasing concentrations of progesterone 1-2 days prior to ovulation. Ovulation occurs approximately two days after the LH-peak. The bitch ovulates primary oocytes with intact germinal vesicle, which requires 2-5 days for the...
Jul 18, 20030
The aim of this study (by means of a field test) has been to compare RODAC plates with two rapid test methods under routine conditions.
Jul 18, 20030
In the mare, the practical use of assisted reproduction techniques has been very limited so far. Embryo transfer is used only in a few countries to a low extent. The main reason for this situation is that there is no practical method available for superovulation in the mare. The majority of equine embryos are therefore collected from spontaneously ovulating mares. Synchronisation of the oestrous cycle of the donor and recipient mare before transfer is of major importance. In synchronized recipie...
Jul 18, 20030
Jul 18, 20030
Vasopressor Agents or Fluid Resuscitation for the Treatment of Uncontrolled Hemorrhagic Shock, an Experimental Approach in a Porcine Liver Trauma Model The standard approach to the traumatized victim in uncontrolled hemorrhagic shock is to infuse large amounts of crystalloid and colloid fluids as early, and as rapidly as possible. The aim of this strategy is to restore intravascular volume immediately and to maintain vital organ perfusion. The results of many laboratory studies and one clinical ...
Jul 18, 20030
