This Week in Virology - podcast cover

This Week in Virology

Vincent Racaniellowww.microbe.tv
TWiV is a weekly netcast about viruses - the kind that make you sick. Brought to you by four university professors and a science writer.
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Episodes

TWiV 1213: Secrets of HepB cccDNA

TWiV reviews new committee of experts to counter vaccine misinformation, resignation of NSF Director, dependence of immune response to rabies virus on the gut microbiome, and a nucleosome switch primes hepatitis B virus infection. Hosts: Vincent Racaniello , Rich Condit , and Angela Mingarelli Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV ASV 2025 Committee of experts to counter vaccine misinformation (Scienc...

Apr 27, 20252 hr 5 minEp. 1213

TWiV 1212: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin with Vincent Racaniello deplore the US's withdrawal from the global health community for pandemic preparedness i.e. the universal avian flu vaccine, and undermining the use of routine childhood vaccinations for pertussis and measles, RFK's autism registry, yellow fever outbreak in Colombia and world immunization week after discussing the squirrel as the reservoir host for mpox, before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-...

Apr 26, 202548 minEp. 1212

TWiV Special: A shot of HepB with Stephan Urban

From the 2024 International Hepatitis B virus meeting in Chicago IL, Rich Condit speaks with Stephan Urban about his career working on HBV and HDV, and his philanthropy. Host: Rich Condit Guest: Stephan Urban Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV ASV 2025 Hepatitis delta : recent advances (Hepatology) Bulevirtide for HBV and HDV (Lancet Inf Dis) Timestamps by Jolene Ramsey. Thanks! Intro music is by R...

Apr 22, 202543 min

TWiV 1211: Moo flu and dengue two

TWiV discusses the rising autism rate among children, RFK Jr.'s claim that autism 'destroys lives', receptor binding specificity of a bovine H5N1 influenza virus, and improved dengue subunit vaccine modified to form E protein dimers. Hosts: Vincent Racaniello , Alan Dove , Rich Condit , and Brianne Barker Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV ASV 2025 Rising autism rate among children (MMWR) RFK Jr. c...

Apr 20, 20251 hr 44 minEp. 1211

TWiV 1210: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin with Vincent Racaniello rue about the continuation of the gutting of the American public health infrastructure, the continuing measles outbreak, an unreported outbreak of deadly E.coli human infections, meningococcal disease before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, ACIP recommended changes in guidelines for the RSV and COVID-19 vaccines, reactogenicity differences between No...

Apr 19, 202547 minEp. 1210

TWiV 1209: Just say no to norovirus

TWiV reviews RFK Jr's odd comments on 'single antigen' vaccines and his September deadline for understanding why autism has increased, dire wolf does not come back from the dead, oral norovirus vaccine tablet that induces mucosal immunity in older adults, and identification of broadly neutralizing human monoclonal antibodies against norovirus. Hosts: Vincent Racaniello , Alan Dove , Kathy Spindler , and Brianne Barker Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links ...

Apr 13, 20251 hr 41 minEp. 1209

TWiV 1208: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin with Vincent Racaniello mourn the demise of vaccination against childhood diseases when discussing the continuing measles outbreak and the rise of pertussis, the first human case of H5N1 in Mexico, and human metapneumovirus before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections and vaccination schedules, the WasterwaterScan dashboard, where to find PEMGARDA, provides information for Columbia University Irving Medical Ce...

Apr 12, 202550 minEp. 1208

TWiV 1207: Taking a shot at dementia

TWiV notes the passing of Klaus Conzelmann, then reviews reverse-zoonoses of 2009 H1N1 pandemic influenza A viruses and evolution in United States swine, and reduction in dementia incidence in recipients of Zostavax. Hosts: Vincent Racaniello , Alan Dove , and Rich Condit Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV ASV 2025 Reverse zoonoses of 2009 H1N1 in US swine (PLoS Path) Zostavax reduces dementia (Nat...

Apr 06, 20251 hr 46 minEp. 1207

TWiV 1206: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin and Vincent Racaniello lament about the continuing measles outbreak, whether or not the measles outbreak was predicted, the FACTS about vaccination, high pathogenic influenza, H5N1 contaminated raw pet food, children's deaths, before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections and vaccination schedules and the efficacy of Moderna's seasonal mRNA vaccine, societal burden of COVID-19 and influenza, the FDA missed dead...

Apr 05, 202550 minEp. 1206

TWiV 1205: Pluviosity didn't kill the bat

TWiV reviews liver damage caused by over use of vitamin A in Texas, vitamin A does not change clinical course of measles in high income country, NIH cuts COVID-19 research, US ends vaccine funds for poor countries, anti-vaxxer hired to study vaccines and autism, new DURC policy, Jamaican fruit bat competence for filoviruses, and human outbreaks of Oropouche virus reassortant in Brazil. Hosts: Vincent Racaniello , Alan Dove , Kathy Spindler , and Brianne Barker Subscribe (free): Apple Podcasts , ...

Mar 30, 20251 hr 44 minEp. 1205

TWiV 1204: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin with Vincent Racaniello rue about the continuing measles outbreak, the FACTS about vaccination, irresponsibility of promoting vitamin A therapy "lifelong liver damage or vaccinaton!", high pathogenic influenza and egg importation before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections and vaccination schedules and if vaccination affects long COVID, the WasterwaterScan dashboard, where to find PEMGARDA, provides informati...

Mar 29, 202551 minEp. 1204

TWiV 1203: What's old is flu again

TWiV explains why RFK Jr.'s proposal to let H5N1 infections in birds 'rip' is a bad idea, phase 1/2 trial of combined influenza/COVID mRNA vaccines, and how your first influenza virus exposure shapes the B cell response to influenza vaccination 50 years later. Hosts: Vincent Racaniello , Rich Condit , and Brianne Barker Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV ASV 2025 RFK Jr. says let H5N1 rip through f...

Mar 23, 20251 hr 57 minEp. 1203

TWiV 1202: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin and Vincent Racaniello rue about the unknowns of Sudan disease and new cases of paralytic polio, discuss the growing measles outbreak, exposure of newborns to measles, the FACTS about vaccination, high pathogenic influenza in dairy cows and cats, RFK's statement "just let the virus rip through the hens" before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, what ha...

Mar 22, 202538 minEp. 1202

TWiV 1201: Booster shots with Adam Ratner

Infectious diseases physician and author of 'Booster Shots' Adam Ratner joins TWiV to discuss measles, measles vaccination, how to approach anti-vaccine sentiment, and the uncertain future of children's' health. Hosts: Vincent Racaniello , Brianne Barker , and Jolene Ramsey Guest: Adam Ratner Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Booster Shots by Adam Ratner The Cutter Incident by Paul Offit Timestamp...

Mar 16, 20251 hr 20 minEp. 1202

TWiV 1200: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin and Vincent Racaniello bemoan the continued outbreak of Sudan virus and growing number of paralytic polio cases before discussing growing measles outbreak in the US and Europe, the vaccine, an interview with a parent whose child died of measles infection, adverse effects of vaccination and how parents do not think they have accurate information about "bird flu" before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections, the...

Mar 15, 202559 minEp. 1200

TWiV 1199: Loosely contained

TWiV covers a second death over 150 cases of measles in Texas, utter failure of removal of type 2 poliovirus from OPV, more OPV doses administered in Gaza, second Ebola outbreak in Sudan, vaccine being tested, Trump administration cancels $400 million in grants to Columbia University, bat-infecting merbecovirus that binds human ACE2 and infects human cells, and innate immune sensing of rotavirus by intestinal epithelial cells leads to diarrhea. Hosts: Vincent Racaniello , Alan Dove , Rich Condit...

Mar 09, 20251 hr 52 minEp. 1199

TWiV 1198: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin with Vincent Racaniello deliberate the effect of the absence of US foreign aid on the Ebola outbreak in Uganda and death of two children, continued use of nOPV2 in Gaza and the utter failure of type 2 poliovirus removal from the oral poliovirus vaccine, growing measles outbreak in the US including the death of a second child, measles infection parties, the use of fat soluble vitamin A and fish liver oil as anti-viral therapies as well as the history and...

Mar 08, 202543 minEp. 1198

TWiV 1197: The long and short of influenza

TWiV reviews passing of Ann Palmenberg, deadly illness in western Congo, US disruption of mpox and ebolavirus programs, first measles death in Texas outbreak, flu vaccine selection meeting postponed, US withdraws from polio, malaria, HIV programs and more, clade 2.3.4.4b H5N1 viruses have a long HA stalk, and systems vaccinology to identify predictors of durable antibody response to multiple vaccines in humans. Hosts: Vincent Racaniello , Alan Dove , Rich Condit , and Brianne Barker Subscribe (f...

Mar 02, 20251 hr 41 minEp. 1197

TWiV 1196: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin and Vincent Racaniello lament about the downfall of public health from "postponement" of the advisory committee on immunization practices and the FDA VRBPAC influenza strain selection meetings to how the communication pause prevents public notice of NIH study section meetings, and withdrawal of CDC promotions for the 'flu vaccine' before discussing the end of Ebola outbreak in Uganda, funding from Saudi Arabia for polio eradication, the continuing and g...

Mar 01, 202559 minEp. 1196

TWiV 1195: Dickson Despommier, parasitologist without borders

The entire TWiV team comes together to pay tribute to Dickson Despommier, then reviews antibodies to H5N1 virus in veterinarians working with dairy cattle, Elisabeth Bik donates prize money for data integrity analyses, measles outbreak in Texas, and use of an alternative genetic code by human microbiome phages. Hosts: Vincent Racaniello , Alan Dove , Rich Condit , Kathy Spindler , Brianne Barker , Daniel Griffin , Angela Mingarelli, and Jolene Ramsey Subscribe (free): Apple Podcasts , RSS , emai...

Feb 23, 20251 hr 52 minEp. 1195

TWiV 1194: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin and Vincent Racaniello reminiscence about Dickson before discussing discharging Ebola patients, another announcement of emergency measures to control polio spread and the third nOPV2 vaccination campaign in Gaza in less than 6 months, the measles outbreak in the US, vaccination campaign for chickens against high pathogenic avian flu before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, w...

Feb 22, 202559 minEp. 1194

TWiV 1193: HPV or not to B

TWiV reviews a facility accident that killed monkeys, new bird blu genotype found in Nevada dairy cattle, Argentina plans to leave WHO, yellow fever on the rise, dynamics of HPV infections in women, and Epstein-Barr virus protein targets B cell receptor for degradation. Hosts: Vincent Racaniello , Alan Dove , and Angela Mingarelli Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV ASV 2025 Accident kills monkeys a...

Feb 16, 20251 hr 43 minEp. 1193

TWiV 1192: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss confirmation of Robert F Kennedy as HHS sectary, mpox, Ebola, how the American people support vaccine development and administration, the measles outbreak in the US-Texas, Georgia and influenza: the number of human infections, high avian flu in mammals, house cats and dairy cows before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, a...

Feb 15, 202544 minEp. 1192

TWiV 1191: The pandemic duo

TWiV reviews freezes and unfreezes of US government grants, how prior COVID-19 vaccination prevents over-reaction of the innate immune response during infections, and how bat genomes illuminate adaptations to viral tolerance and disease resistance. Hosts: Vincent Racaniello and Alan Dove Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV ASV 2025 NIH freezes (ScienceAdviser) Is your research on Trump's hit list ? ...

Feb 09, 20251 hr 45 minEp. 1191

TWiV 1190: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss changes in access to public health information and aid mechanisms such as the return of MMWR, the largest tuberculosis outbreak in the US ever, lack of USAID in fighting Marburg and Ebola outbreaks in Africa, discussing if avian influenza virus is airborne, how eggs are effected and the emergence of second spillover into dairy cattle, how the difference between nOPV2 and Sabin OPV2 is a minor reduction in the association o...

Feb 08, 202547 minEp. 1190

TWiV 1189: Viruses making waves

TWiV notes the HHS communication pause, and describes research showing that rotavirus viroporin activity is necessary for intracellular calcium signals that contribute to viral pathogenesis, and control of human orthrflavivirus vaccine challenge by T cells in the absence of neutralizing antibodies. Hosts: Vincent Racaniello , Alan Dove , Kathy Spindler , and Brianne Barker Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Support science education at ...

Feb 02, 20251 hr 33 minEp. 1189

TWiV 1188: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss changes in access to public health information, the Marburg and Ebola outbreaks in Africa, the largest tuberculosis outbreak in the US ever, the politicization of polio vaccine campaigns in Pakistan, effect of high pathogenic influenza in animals and on the economy before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, provides inform...

Feb 01, 202548 minEp. 1188

TWiV 1187: The tau of herpesvirus

TWiV explains a new blood test for head and neck cancer, Japanese regulators approve tecovirimat for mpox, an entry receptor for enterovirus D68, and anti-herpetic tau preserves neurons via a DNA sensing pathway in Alzheimer's disease. Hosts: Vincent Racaniello , Alan Dove , Kathy Spindler , Brianne Barker , and Angela Mingarelli Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV ASV 2025 Entry receptor for EV-D68...

Jan 26, 20251 hr 57 minEp. 1187

TWiV 1186: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin and co-host Vincent Racaniello lament about the public changes from withdrawing from the WHO to health and scientific communication pauses by the Trump Administration after a brief discussion of Marburg in Tanzania and mpox in England before reviewing cats and bird flu, the recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, where to find PEMGARDA, provides information for Columbia University Irving Medical Cent...

Jan 25, 202547 minEp. 1186

TWiV 1185: The birds and the Bs

TWiV explains Guillain-Barré Syndrome associated with RSV vaccines, outbreaks of metapneumovirus in China and India, editors resign to protest Elsevier's use of AI in publishing, global distribution and diversity of wild bird associated pathogens, and broadly inhibitory anti-neuraminidase antibody from human memory B cells. Hosts: Vincent Racaniello , Alan Dove , Rich Condit , and Brianne Barker Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Suppor...

Jan 19, 20251 hr 52 minEp. 1185
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