TWiV 1199: Loosely contained

TWiV covers a second death over 150 cases of measles in Texas, utter failure of removal of type 2 poliovirus from OPV, more OPV doses administered in Gaza, second Ebola outbreak in Sudan, vaccine being tested, Trump administration cancels $400 million in grants to Columbia University, bat-infecting merbecovirus that binds human ACE2 and infects human cells, and innate immune sensing of rotavirus by intestinal epithelial cells leads to diarrhea.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler

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• ASV 2025
• Second child dies of measles (NY Times)
• Over 150 measles cases in Texas (Texas DSHS)
• Utter failure of removal of OPV2 from OPV (Science)
• Over 600,000 doses of OPV administered in Gaza (polioeradication)
• Second outbreak of Sudan Ebola in Uganda (IAVI)
• Columbia grants canceled by administration (NBC News)
• Bat merbecovirus also infects human cells via Ace2 (Cell)
• Recent virus research, was proper containment used? (NY Times)
• Innate immune sensing of rotatvirus leads to diarrhea (Cell Host Microbe)
• Timestamps by Jolene Ramsey. Thanks!

Kathy – Mice cry out when they urinate, and give mouth to mouth resuscitation Rich – Firefly Aerospace Alan – Strong Museum of Play Vincent – How a PhD student's lab size affects their chance of future academic success

Larry – James Harrison's rare blood protected many infants

Intro music is by Ronald Jenkees

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Content in this podcast should not be construed as medical advice.