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TWiV explains research on human influenza virus transmission that reveals heterogeneous expulsion of infectious virus into air, and how gut bacteriophages dictate inflammation heterogeneity through tuning the phage-bacteria-sphingosine-intestine axis in Crohn's disease. Hosts: Vincent Racaniello , Rich Condit , Brianne Barker , and Jolene Ra m sey Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Positions in Ros...
In his weekly clinical update, Daniel Griffin and Vincent Racaniello comment on incidences of locally transmitted malaria in the US, mpox diagnostics, the latest developments surrounding hantavirus infections, and the Ebola outbreak in the Congo and Uganda including vaccine candidates before Dr. Griffin deep dives into the measles outbreak, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, the measles outbreak in Texas in 2...
Vincent travels to Oregon State University in Corvallis to meet up with Hannah Rowe to talk about her career and her work demonstrating how the interaction of influenza A virus and Streptococcus pneumonia influences transmission. Hosts: Vincent Racaniello Guest: Hannah Rowe Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Positions in Rosenfeld Lab (email) Respiratory bacteria stabilize influenza A virus (mSyste...
In his weekly clinical update, Daniel Griffin and Vincent Racaniello discuss withdrawal of the ACIP charter published in April 2026, the first council meeting on antibiotic resistant bacteria, the latest developments surrounding hantavirus infections, and the Ebola outbreak in the Congo and Uganda before Dr. Griffin deep dives into the measles outbreak, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, transmission of SARS-...
TWiV explains mRNA delivery of mosaic-8 pan-sarbecovirus RBD vaccines, and how toll-like receptor 7 alters the maternal immune landscape during influenza A infection to increase maternal and fetal morbidity, Hosts: Vincent Racaniello , Rich Condit , and Kathy Spindler Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Positions in Rosenfeld Lab (email) RFK Jr. driving vast inquiry into vaccines (NY Times) Indiana ...
Dr. Daniel Griffin and Vincent Racaniello dive deep into the hantavirus outbreak, critically examining the CDC's interim guidance on exposure, contact tracing, and management, including controversial travel advice. They discuss the nature of Andes virus transmission, its zoonotic origins versus potential human adaptation, and share insights from past outbreaks and a doctor's firsthand experience on the cruise ship. Additionally, the episode provides updates on measles cases, new data on an mRNA influenza vaccine, maternal RSV vaccination for infant protection, and challenges misconceptions about COVID-19 mortality and post-exposure prophylaxis.
TWiV explains how cross-reactive anti-prophage antibodies and bacterial heteroresistance is implicated in phage therapeutic failure, and how phages communicate across species to shape microbial ecosystems. Hosts: Vincent Racaniello , Rich Condit , Brianne Barker , and Jolene Ramsey Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Positions in Rosenfeld Lab (email) Craig Venter dies (Nature) Hantavirus outbreak (...
In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss the outbreak of Hantavirus on a cruise ship and its potential for person-person transmission, how cessation of funding for global health by the Trump administration has compromised American health and well being, as well as the description of paralytic poliomyelitis outbreaks in Central Africa associated with the administration of nOPV2, before Dr. Griffin deep dives into the measles outbreak, recent statistics RSV, influe...
TWiV explains the emergence of vaccine-derived poliovirus strains from the novel oral polio vaccine in the Central African Republic, and the infection of spiral ganglion neurons in the inner ear by SARS-CoV-2, which may explain hearing loss in humans. Hosts: Vincent Racaniello , Alan Dove , and Kathy Spindler Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Positions in Rosenfeld Lab (email) Bernard Roizman dies...
In his weekly clinical update, Dr. Griffin and Vincent Racaniello note the uncertain future of the National Science Foundation amid shifting U.S. funding priorities and governance; the rise of China as a global research powerhouse; ongoing advances and controversies in vaccines shaped by the World Health Organization and the Centers for Disease Control and Prevention; vaccine policy battles in Florida; European approval of the moderna mCOMBRIAX, COVID-19 and influenza vaccine, the mounting evide...
TWiV explains a study showing that viral DNA load in blood and saliva varied markedly with age, time of day season, sex, and depended on dozens of genetic loci, and identification of an emerging human eye disease associated with aquatic virus zoonotic infection. Hosts: Vincent Racaniello , Alan Dove , Rich Condit , and Brianne Barker Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Positions in Rosenfeld Lab (em...
In his weekly clinical update, Dr. Griffin and Vincent Racaniello are distressed by RFK Jr's testimony in front of Congress, surges in rotavirus infections and the staggering number of people who believe in unproven claims about vaccines and science, before Dr. Griffin then deep dives into the measles outbreak, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, the fatal consequences of measles infection, prevalence of influ...
TWiV explains a study showing that the wildlife trade, including live-animal markets, is a major driver of animal-to-human pathogen transmission, and ecological vaccination, a strategy to prevent zoonotic spillover from bats. Hosts: Vincent Racaniello , Alan Dove , Rich Condit , and Angela Mingarelli Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Positions in Rosenfeld Lab (email) Bernard Roizman passes ( Wiki...
TWiV 1314: Clinical update with Dr. Daniel Griffin April 17, 2026 In his weekly clinical update, Dr. Griffin and Vincent Racaniello are dismayed but not surprised by poll results suggesting most Americans doubt vaccine safety, that the head of the CDC and NIH delayed release of a report on the safety of the COVID-19m vaccine, how Nature works to spread disease without the help of the lab and the about face of the Trump administration to nominate a pro-vaccine candidate for CDC director, before D...
TWiV reviews evidence that influenza standard and high-dose vaccines reduce risk of Alzheimer's dementia, and spread of deltaviruses by a viral Trojan horse mechanism. Hosts: Vincent Racaniello , Alan Dove , and Rich Condit Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Positions in Rosenfeld Lab (email) Dennis O'Callaghan passes ( Wikipedia , LSU ) Reduced dementia risk after influenza vaccine (Neurology) Del...
In his weekly clinical update, Dr. Griffin and Vincent Racaniello are aghast at the CDC's decision to no longer test for rabies and mpox and the revised charter for its the advisory committee on immunization practices, an outbreak of E. coli illness in raw cheese, before Dr. Griffin then deep dives into the measles outbreak, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, clinical practice guidelines for treating COVID-19...
Vincent visits the University of Kansas and speaks with Tony Fehr, Robin Orozco, Juergen Richt and Rob Unckless about their careers and the research ongoing in their laboratories. Host: Vincent Racaniello Guests: Tony Fehr , Robin Orozco , Juergen Richt , and Rob Unckless Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV PARP14 affects replication of multiple viruses (mBio) PTPN22 allele enhances innate antiviral...
In his weekly clinical update, Dr. Griffin and Vincent Racaniello cover if the "five-second" rule for things that fall on the floor apply to surgical equipment, an outbreak of E. coli illness caused by raw cheese before Dr. Griffin then deep dives into the measles outbreak in South Carolina and Utah, recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, where to find PEMGARDA, strain selection for the 2026-2027 season influenza...
TWiV explains why human papillomavirus vaccine-induced immunity can block infection, unlike all other vaccines, and how respiratory viral infections such as COVID and influenza prime accelerated lung cancer growth. Hosts: Vincent Racaniello , Alan Dove , Rich Condit , and Brianne Barker Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Positions in Rosenfeld Lab (email) J. Michael Bishop passes (NY Times) Vincent...
In his weekly clinical update, Dr. Griffin and Vincent Racaniello talk about the resignation of a member of the advisory committee for immunization practices and the irony of his rationale that a judge slandered him, vaccinating dairy cattle against H5N1, illnesses resulting from drinking raw milk and the US norovirus outbreak, which is not cruise related, then Dr. Griffin deep dives into the measles outbreak in South Carolina and Utah, recent statistics RSV, influenza and SARS-CoV-2 infections,...
TWiV reviews the structural basis for Rep-mediated adeno-associated virus DNA genome packaging, how influenza virus-infected myeloid cells travel to the heart and infect cardiomyocytes, leading to IFN-fueled heart damage. Hosts: Vincent Racaniello , Rich Condit , Kathy Spindler , and Brianne Barker Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Positions in Rosenfeld Lab (email) Robin Weiss passes (ICR) Judge ...
In his weekly clinical update, Dr. Griffin and Vincent Racaniello chat about death of water fowl on Long Island, 'renaming' of the FDA adverse event monitoring system, lawsuits against RFK Jr and HHS for illegal changes in routine immunization practices, before Dr. Griffin deep dives into economic costs of not vaccinating against measles, the measles outbreak in South Carolina, Utah and ICE detention centers, recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan das...
TWiV introduces sunshine virus of carpet pythons and its effect snakes after experimental infection, and development of a new tool to distinguish between naturally ocurring outbreaks and those that arise from lab accidents. Hosts: Vincent Racaniello , Alan Dove , Rich Condit , and Brianne Barker Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Positions in Rosenfeld Lab (email) IgNobel Prize ceremony moved to Eu...
In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss the global spread of the 'eradicated' poliovirus, the suggestion of RFK's autocratic ability to change vaccine policy and the 'resignation' for the second time of CBER director Vinjay Prasad, and zoonotic spillover of viruses without adaptation, before Dr. Griffin deep dives into economic costs of not vaccinating against measles, the measles outbreak in South Carolina, Utah and ICE detention centers, recent statistics RSV,...
TWiV reviews an association between shingles vaccination and slower biological aging, and how mucosal immunization in mice provides protection against disease caused by diverse viruses and bacteria. Hosts: Vincent Racaniello , Alan Dove , Rich Condit , and Brianne Barker Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Positions in Rosenfeld Lab (email) Shingles vaccination may slow biological aging (J Gerontol)...
In his weekly clinical update, Dr. Griffin and Vincent Racaniello talk about the health misconceptions that RFK Jr continues to perpetuate and how to combat them, first cases of highly pathogenic influenza in the California elephant seal population before Dr. Griffin deep dives into economic costs of not vaccinating against measles, the measles outbreak in South Carolinaand Utah, ICE detention centers, lack of accurate reporting may prevent the US from losing its status as a country that elimina...
TWiV reviews lymphocytic choriomeningitis virus seroprevalence among urban pregnant women and newborns in Philadelphia, and a functional translation initiation complex encoded in the genome of giant viruses that drives synthesis of viral structural proteins. Hosts: Vincent Racaniello , Rich Condit , Kathy Spindler, and Angela Mingarelli Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Positions in Rosenfeld Lab ...
In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss several states and the governor of Pennsylvania suing HHS over changes in the childhood vaccination schedule, the vaccine derived type 2 poliovirus outbreak in Pakistan and implications for the global withdrawal of the oral poliovirus vaccine, and the outbreak of Candida, then Dr. Griffin deep dives into recent statistics RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracke...
TWiV explains how vaccine-induced thrombotic thrombocytopenia develops from antibodies to adenovirus and somatic hypermutation, and castration by a viral protein tyrosine phosphatase that targets a host cell cycle checkpoint protein. Hosts: Vincent Racaniello , Alan Dove , Rich Condit , and Brianne Barker Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Positions in Rosenfeld Lab (email) US repeals environmental...
In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss reversal of last week's no review decision on a flu mRNA vaccine by Vinjay Prasad, appointment of Jay Bhattacharya as CDC director, no experience required, and already detectable reduction in hepatitis B virus vaccination rates, then Dr. Griffin then deep dives into recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, where to find PEMGARDA, how to ac...
