TWiV 1332: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Daniel Griffin and Vincent Racaniello express concern about vaccine policy and ACIP, scaling back of the CDC's role in global public health, shingles vaccine and dementia, new screwworm cases, the Ebola outbreak in the Congo and Uganda and where the hantavirus outbreak began, before Dr. Griffin deep dives into the measles outbreak, recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, Virgina outbreak of measles, how to access and pay for Paxlovid, how more people were negatively impacted by influenza than COVID, discontinuing contact precautions for COVID, where to go for answers about long COVID-19, and contacting your federal government representative to stop the assault on science and biomedical research.

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• Today we filed a motion asking the First Circuit to expedite our appeal of the district court's order in the AAP lawsuit that left ACIP—the nation's vaccine advisory committee—without a quorum (X)
• CDC advisers drop decades-old universal hepatitis B birth dose recommendation, suggest blood testing after 1 dose (CIDRAP)
• HHS asks for expedited appeal of court ruling on US vaccine policy (CIDRAP)
• New Plan Scales Back C.D.C.'s Work on Diseases Abroad (NY Times)
• Zoster Vaccination and Dementia: Interpreting the Signal and Testing the Mechanisms (CID)
• Safety and Immunogenicity of 1 or 2 Additional Doses of the Adjuvanted Recombinant Zoster Vaccine Administered 5–6 Years After Primary Vaccination in Adults ≥50 Years (OFID)
• Dashboard SCREWWORM.Gov (USDA: Animal and Plant Health Inspection Service)
• CDC Activates Emergency Operations Center for New World Screwworm Response (CDC Newroom)
• Head-to-head comparison suggests flu was much more likely to lead to hospitalization than COVID last winter (CIDRAP)
• FDA Issues Emergency Use Authorization for Generic Over-the-Counter Drug to Treat New World Screwworm in Dogs and Cats (FDA)
• Fact Sheet: Emergency Use Authorization of Nitenpyram Tablets (nitenpyram) for New World Screwworm (NWS) (FDA)
• Ebola dashboard (ebola.fyi)
• EBOLA:The Democratic Republic of the Congo, 2026 (WHO)
• Bundibugyo virus disease outbreak Democratic Republic of the Congo (WHO: Democratic Republic of Congo)
• Ebola Outbreak: Current Situation (CDC:Ebola)
• Big Ebola outbreak puts spotlight on little known virus (Science)
• Ebola outbreak spreads to crowded displacement camp in Congo (Reuters)
• Ebola outbreak in DR Congo expands into large displacement camp (CIDRAP)
• Congo Ebola outbreak may be worst ever, Africa CDC says (Reuters)
• Advocacy groups are urging the release of the monoclonal antibody MBP134 and any other requested investigational therapeutics (Citizen.org)
• Hantavirus dashboard (Hantavirus.up
• Hantavirus on board with Prof. Vincent Racaniello (microbeTV)
• How did the cruise ship hantavirus outbreak start? (Science)
• Wastewater for measles (WasterWater Scan)
• Measles cases and outbreaks (CDC Rubeola)
• Big outbreak, bright lights…Measles Dashboard( South Carolina Department of Public Health)
• Utah measles outbreak response (Utah Department of Health and Human Services)
• UtahMeasles Dashboard (Utah Department of Health and Human Services)
• US measles cases continue to climb, especially in Virginia(CIDRAP)
• Measles (VDH: Virginia Department of Health)
• Tracking Measles Cases in the U.S. (Johns Hopkins)
• Measles vaccine recommendations from NYP (jpg)
• Weekly measles and rubella monitoring (Government of Canada)
• Measles (WHO)
• Get the FACTS about measles (NY State Department of Health)
• Measles (CDC Measles (Rubeola))
• Measles vaccine (CDC Measles (Rubeola))
• Presumptive evidence of measles immunity (CDC)
• Contraindications and precautions to measles vaccination (CDC)
• Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
• Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America)
• Deaths following vaccination: what does the evidence show (Vaccine)
• Anguished Parents, Crying Doctors: Life Amid Utah's Measles Outbreak (Wired)
• Characteristics of Patients Hospitalized with Measles During an Outbreak — West Texas, January–March 2025 (CDC:MMWR)
• Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
• USrespiratory virus activity (CDC Respiratory Illnesses)
• Respiratory virus activity levels (CDC Respiratory Illnesses)
• Flu vaccine recommendations: Vaccines and Related Biological Products Advisory Committee March 12, 2026 Meeting Announcement (FDA)
• WHO updates all 3 viral strains to be included in fall flu shots (CIDRAP)
• FDA vaccine advisers recommend adding subclade K to fall shots (CIDRAP)
• Weekly surveillance report: clift notes (CDC FluView)
• Influenza Vaccine and Associated Infection and Death in California, 2024 to 2025 (JAMA Network OPEN)
• OPTION 2: XOFLUZA $50 Cash Pay Option (xofluza)
• RSV: Waste water scan for 11 pathogens (WastewaterSCan)
• Respiratory Diseases (Yale School of Public Health)
• USrespiratory virus activity (CDC Respiratory Illnesses)
• RSV-Network (CDC Respiratory Syncytial virus Infection)
• Vaccines for Adults (CDC: Respiratory Syncytial Virus Infection (RSV))
• Economic Analysis of Protein Subunit and mRNA RSV Vaccination in Adults aged 50-59 Years (CDC: ACIP)
• Respiratory Diseases (Yale School of Public Health)
• Waste water scan for 11 pathogens (WastewaterSCan)
• COVID-19 deaths (CDC)
• Respiratory Illnesses Data Channel (CDC: Respiratory Illnesses)
• COVID-19 national and regional trends (CDC)
• COVID-19 variant tracker (CDC)
• SARS-CoV-2 genomes galore (Nextstrain)
• Seasonal influenza versus COVID-19 hospitalisation risk during the 2025–26 influenza season (LANCET: Infectious Diseases)
• Discontinuingcontact precautions for COVID-19: the science says its time (Infection Control and Hospital Epidemiology)
• 2024-2025 COVID-19 Vaccine and Major Adverse Cardiovascular Events Among US Veterans (JAMA Internal Medicine)
• Where to get pemgarda (Pemgarda)
• EUAfor the pre-exposure prophylaxis of COVID-19 (INVIYD)
• Infusion center (Prime Fusions)
• CDC Quarantine guidelines (CDC)
• NIH COVID-19 treatment guidelines (NIH)
• Drug interaction checker (University of Liverpool)
• Help your eligible patients access PAXLOVID with the PAXCESS Patient Support Program (Pfizer Pro)
• UnderstandingCoverageOptions (PAXCESS)
• Infectious Disease Society guidelines for treatment and management (ID Society)
• Molnupiravir safety and efficacy (JMV)
• Convalescent plasma recommendation for immunocompromised (ID Society)
• What to do when sick with a respiratory virus (CDC)
• Managing healthcare staffing shortages (CDC)
• Anticoagulation guidelines (hematology.org)
• Daniel Griffin's evidence based medical practices for long COVID (OFID)
• Long COVID hotline (Columbia University Irving Medical Center)
• The answers: Long COVID Reaching out to US house representative
• Letters read on TWiV 1332
• Dr. Griffin's COVID treatment summary (pdf)
• Timestamps by Jolene Ramsey. Thanks!

Intro music is by Ronald Jenkees

Send your questions for Dr. Griffin to daniel@microbe.tv

Content in this podcast should not be construed as medical advice.