Synthetic technologies allow scientists to venture into uncharted waters, asking unique research questions and finding previously unattainable solutions to some of life’s biggest mysteries. From gene editing to protein engineering, synthesized DNA libraries enable researchers to grasp once unreachable high-throughput screening applications and dismantle barriers between experimental ideation and execution. In this podcast series, Synthetic Screens, Genes, and De Novo Proteins, The Scientist’s Cr...
Sep 17, 2024•17 min
Synthetic technologies allow scientists to venture into uncharted waters, asking unique research questions and finding previously unattainable solutions to some of life’s biggest mysteries. From gene editing to protein engineering, synthesized DNA libraries enable researchers to grasp once unreachable high-throughput screening applications and dismantle barriers between experimental ideation and execution. In this podcast series, Synthetic Screens, Genes, and De Novo Proteins, The Scientist’s Cr...
Sep 03, 2024•13 min
Synthetic technologies allow scientists to venture into uncharted waters, asking unique research questions and finding previously unattainable solutions to some of life’s biggest mysteries. From gene editing to protein engineering, synthesized DNA libraries enable researchers to grasp once unreachable high-throughput screening applications and dismantle barriers between experimental ideation and execution. In this podcast series, Synthetic Screens, Genes, and De Novo Proteins, The Scientist’s Cr...
Aug 20, 2024•17 min
With a track record of invention and translating technology into practical solutions, Walker Inman continues to drive innovation in the life sciences field. Inman is currently the cofounder and CEO of Lucid Scientific Inc., a company that develops cellular analysis tools. In this Science Philosophy in a Flash podcast episode brought to you by Lucid Scientific, The Scientist spoke with Inman about the challenges of measuring oxygen concentration in cell culture and how his real-time oxygen monito...
Jul 01, 2024•3 min
Lauren Drouin is the director of analytical development and the Genomic Medicine Unit at Alexion AstraZeneca Rare Disease. As a dynamic scientist with unique expertise in current research and industry trends for gene therapies, Drouin is passionate about driving progress within the rare disease field and advancing products from preclinical development into the clinic and beyond. In this Science Philosophy in a Flash podcast episode brought to you by Bio-Rad, The Scientist’s Creative Services Tea...
Jan 02, 2024•3 min
Researchers commonly employ lentiviruses to modify cells genetically. However, they must overcome several challenges when using these viruses in the laboratory or clinic. In this episode, Charlene Lancaster from The Scientist’s Creative Services Team spoke with Filippo Rossignoli, instructor in neurosurgery at the Center for Stem Cell and Translational Immunotherapy at Brigham and Women's Hospital and Harvard Medical School, about using lentiviruses to engineer cell therapies and the troubleshoo...
Dec 20, 2023•14 min
Scientists continuously develop new assays to fill unmet diagnostic needs. While methods such as quantitative PCR have emerged as essential tools in molecular diagnostics, scientists developing and administering these assays still must overcome technical challenges. In this podcast series, The Scientist’s Creative Services Team talks to experts about their experiences designing and implementing assays and protocols for future molecular diagnostics. In this episode, Deanna MacNeil from The Scient...
Oct 24, 2023•13 min
Scientists continuously develop new assays to fill unmet diagnostic needs. While methods such as quantitative PCR have emerged as essential tools in molecular diagnostics, scientists developing and administering these assays still must overcome technical challenges. In this podcast series, The Scientist’s Creative Services Team talks to experts about their experiences designing and implementing assays and protocols for future molecular diagnostics. In this episode, Deanna MacNeil from The Scient...
Aug 29, 2023•13 min
Scientists commonly use qPCR applications in molecular diagnostics to detect pathogens, assess viral loads, or uncover mutations. While the qPCR assay itself may seem straightforward, other aspects such as data collection and security, and following regulatory guidelines, present challenges. In this episode, Gloria Lam, the associate director of qPCR software for Thermo Fisher Scientific, discusses concerns surrounding molecular diagnostic data collection, analysis, cybersecurity, and more. Welc...
Jun 27, 2023•8 min
Welcome to Molecular Diagnostics: An Eye Toward the Future, a special edition podcast series produced by The Scientist’s Creative Services Team. This series is brought to you by Thermo Fisher Scientific, a world leader in serving science. Their mission is to enable customers to make the world healthier, cleaner, and safer. Whether their customers are accelerating life sciences research, solving complex analytical challenges, improving patient diagnostics and therapies, or increasing productivity...
May 31, 2023•13 min
Translational research cannot be conducted in a vacuum. For a translational researcher to be successful, they need to build strong relationships with individuals, companies, and institutions that will provide useful support and expertise. In this episode, Linda Mathiasson, Strategic Customer Leader for Nucleic Acid Therapeutics at Cytiva, discusses the flourishing translational field of mRNA therapies and opportunities for researchers to form worthwhile partnerships that support their therapeuti...
Apr 19, 2023•18 min
In this episode, Guangping Gao, professor and director of the Horae Gene Therapy Center at the University of Massachusetts Medical School, speaks about developing human gene therapies using recombinant adeno-associated viral vectors, scaling up these therapies, and the future of translational research. Welcome to Building Bridges for Translational Research, a special edition podcast series produced by The Scientist’s Creative Services Team. This series is brought to you by Cytiva, a global provi...
Apr 12, 2023•21 min
Welcome to Building Bridges for Translational Research, a special edition podcast series produced by The Scientist’s Creative Services Team. This series is brought to you by Cytiva, a global provider of technologies and services that advance and accelerate therapeutic development, manufacturing, and delivery. To take preclinical concepts to the market, translational researchers must build strong relationships and forge fruitful partnerships that support their work. In this podcast series, Niki S...
Apr 05, 2023•18 min
Immunotherapies are promising as a holy grail for cancer treatment, but patient responses to these interventions are often variable in both solid tumors and blood cancers. In this episode, Iris Kulbatski from The Scientist’s Creative Services Team spoke with Olli Dufva, a physician and doctoral researcher at the University of Helsinki’s Hematology Research Unit, about his work analyzing the genomic landscape of hematological cancers. Coupling next-generation techniques with traditional methods s...
Dec 13, 2022•20 min
Through epigenetic mechanisms, some environmental toxicants, such as heavy metals, reversibly alter gene expression patterns that then drive cancer progression. In this episode, Yvonne Fondufe-Mittendorf discusses her work studying environmental toxicants and their effects on DNA methylation and chromatin structure. Welcome to Exposed: Environmental Echoes in Health, a special edition podcast series produced by The Scientist’s Creative Services Team. This series is brought to you by Van Andel In...
Oct 19, 2022•14 min
Substances that enter the body, such as food or chemicals, can make epigenetic changes in the germline that become inherited, affecting the health of future generations. In this episode, Heidi Lempradl discusses her work studying the effects of parental diet on their offspring. Welcome to Exposed: Environmental Echoes in Health, a special edition podcast series produced by The Scientist’s Creative Services Team. This series is brought to you by Van Andel Institute, an independent biomedical rese...
Oct 12, 2022•14 min
Welcome to Exposed: Environmental Echoes in Health, a special edition podcast series produced by The Scientist’s Creative Services Team. This series is brought to you by Van Andel Institute, an independent biomedical research institute devoted to improving human health for generations to come. While the human body’s cells all use the same set of instructions, they can end up with wildly different features and functions. Beyond the information stored in DNA, factors within a person’s environment,...
Oct 05, 2022•12 min
The brain’s intractable nature makes neurodegenerative disorders challenging to study, but modern assays and technologies give scientists a fresh look at this complex organ. In this episode, Niki Spahich from The Scientist’s Creative Services Team spoke with Erdem Gültekin Tamgüney, a professor in the Institute of Physical Biology at Heinrich Heine University Dusseldorf, about technologies driving modern neuroscience research and his own work exploring the link between ischemic stroke and Parkin...
Sep 28, 2022•16 min
As smart devices become commonplace in many homes, they also enter life science laboratories with the promise to enhance productivity, simplify collaborations, and produce reliable results. In this episode, Niki Spahich from The Scientist’s Creative Services team spoke with experts from MilliporeSigma about how smart devices change research for the better. LabTalk is a special edition podcast produced by The Scientist's Creative Services Team, where we explore topics at the leading edge of innov...
May 23, 2022•15 min
Cancer immunotherapies are saving lives, but researchers still have a long journey ahead of them. Many cancers that are initially sensitive to immunotherapy acquire resistance over time, while others are resistant from the beginning. In this episode, Niki Spahich from The Scientist’s Creative Services team spoke with Stephanie Dougan, an associate professor of immunology at Harvard Medical School and a principal investigator at Dana Farber Cancer Institute, about her research developing new immu...
Nov 29, 2021•12 min
Childhood cancer is devastating. Every year over 15,000 children in the United States are diagnosed with cancer, with leukemia accounting for 28% of all childhood cancers in children under the age of 15. Leukemia, however, is not a single class of cancer. There are numerous forms of leukemia each with its own distinct cause. In this episode, Tiffany Garbutt from The Scientist’s Creative Services team spoke with Charles Mullighan, member of the department of pathology and deputy director of the C...
Oct 31, 2021•16 min
A diverse population of microglial cells resides in the brain. Similar to immune cells, microglial cells respond to minute changes in their environment. Sometimes this response is beneficial and other times detrimental. Scientists are working to tease apart the dynamic role of microglial response in the pathogenesis of neurodegenerative diseases such as Alzheimer’s disease. In this episode, Tiffany Garbutt from The Scientist’s Creative Services team spoke with Samuel Marsh, a postdoctoral resear...
Jul 31, 2021•17 min
The liver performs approximately 500 separate functions in the human body. With liver disease on the rise, scientists are developing treatments to save this irreplaceable organ. In this episode, Niki Spahich from The Scientist’s Creative Services team spoke with Prakash Ramachandran, a clinician scientist at the Centre for Inflammation Research at the University of Edinburgh, about mechanisms of scarring that lead to chronic liver disease and what he hopes to learn from biobanked patient liver s...
Jun 30, 2021•15 min
Motor neurons originating in the spine control both voluntary and involuntary movements. Even though they have an essential function, they are notoriously difficult to study. In this episode, Niki Spahich from The Scientist’s Creative Services team spoke with Jacob Blum, a graduate student in Aaron Gitler’s laboratory at Stanford University, about his work understanding the diversity of spinal motor neurons using single cell transcriptomics. The Scientist Speaks is a podcast produced by The Scie...
May 05, 2021•14 min
Chimeric antigen receptor (CAR) T cell immunotherapies hold great promise for cancer treatment, but they are not very effective against solid tumors. Niki Spahich from The Scientist’s Creative Services team spoke with Katie McKenna, postdoctoral fellow in the laboratory of Malcolm Brenner at the Center for Cell and Gene Therapy at Baylor College of Medicine, about her work developing a combination CAR T cell immunotherapy and oncolytic virotherapy to treat solid tumors. LabTalk is a special edit...
Apr 28, 2021•14 min
LabTalk is a special edition podcast produced by The Scientist’s Creative Services Team, where we explore topics at the leading edge of innovative research. This episode is brought to you by Keystone Symposia. Don’t miss their upcoming virtual eSymposia Synthetic Biology: At the Crossroads of Genetic Engineering and Human Therapeutics on May 3-4, 2021. One of the eSymposium’s speakers is Cammie Lesser, an associate professor at Massachusetts General Hospital and Harvard Medical School. Niki Spah...
Apr 17, 2021•12 min
The human immune system is highly complex and variable. Some people mount robust responses to infection, vaccination, or immunotherapy, while others fail to react appropriately. These differences have obvious implications for health and disease, and they have been especially appreciated during the COVID-19 pandemic as some individuals show no symptoms after contracting SARS-CoV-2 while others experience severe, life-threatening disease. In this episode, Niki Spahich from The Scientist’s Creative...
Mar 31, 2021•17 min
The Scientist’s LabTalk is a special edition podcast produced by The Scientist’s Creative Services Team where we explore topics at the leading edge of innovative research. In this episode, Niki Spahich from The Scientist’s Creative Services team spoke with Josh Snow, Director of Business Development and Marketing Strategy at Mirus Bio, about the past, present, and future of gene therapy, with a focus on how researchers can transition their successful therapies to clinical trials and the market, ...
Dec 11, 2020•30 min
Welcome to The Scientist’s LabTalk, a special edition podcast produced by The Scientist’s Creative Services Team where we explore topics at the leading edge of innovative research. This episode is brought to you by Keystone Symposia. Don’t miss their upcoming virtual eSymposia Tuberculosis: Science Aimed at Ending the Epidemic on December 2-4, 2020. One of the symposium’s co-organizers and keynote speaker is David Alland, Chief of Infectious Disease and Director of the Center for Emerging Pathog...
Nov 13, 2020•13 min
Welcome to The Scientist’s LabTalk, a special edition podcast produced by The Scientist’s Creative Services Team where we explore topics at the leading edge of innovative research. In this episode, we explore how neurons withstand stress by looking at three cutting edge technologies: CRISPR, stem cell technology, and single-cell sequencing. Tiffany Garbutt from The Scientist’s Creative Services team spoke with Martin Kampmann, associate professor at the University of California San Francisco, Ch...
Oct 20, 2020•18 min
