What if you could ditch your glasses forever by simply doing a 10-minute exercise each day? In this episode, Dave sits down with Dr. Bryce Appelbaum, a visionary in vision biohacking, to uncover how simple techniques can transform your eyesight. From near-far focusing to eye stretches, these exercises don’t just improve your vision—they enhance your brain’s performance, energy, and overall health. Dr. Bryce shares his own journey of overcoming severe vision challenges, the science be...
Jan 09, 2025•58 min•Ep. 1240
What if the secret to living to 250 was simply sitting in the garden? In this episode, Dave sits down with Christian Drapeau, a leading expert in stem cell science, to explore the plants and natural practices that could unlock extreme longevity. From goji berries to reishi mushrooms, these age-old remedies do more than nourish—they activate your body’s innate repair system, boosting stem cells and accelerating healing. Christian dives into the fascinating stories behind these plants,...
Jan 07, 2025•56 min•Ep. 1239
Are we protecting our kids—or unknowingly putting their health at risk? Dr. Joel “Gator” Warsh isn’t just another pediatrician; he’s a bold voice speaking out on the vaccine debate that’s dividing parents, doctors, and society. In this episode, we pull back the curtain on one of the most censored and controversial topics of our time. With his integrative and functional approach, Dr. Warsh unpacks the startling rise in chronic illnesses among children and questions if we’re truly aski...
Jan 02, 2025•1 hr 26 min•Ep. 1238
Your hearing isn’t just about sound—it’s the key to sharper focus, deeper connections, and increased awareness. In this episode, Dave explores the cutting-edge world of hearing technology with Brandon Sawalich, CEO of Starkey, and reveals how you can gain superhuman hearing with almost no effort. “Listening” to this episode is going to be one of the best things for your hearing. But why? Because your hearing isn’t just about detecting sounds—it’s about transforming the way you experience the wor...
Dec 31, 2024•47 min•Ep. 1237
Fear is quietly running your life—and it’s holding you back from the purpose and success you deserve. In this episode, we revisit Dave chatting with one of the keynote speakers for the Biohacking Conference 2025, Ryan Holiday, the bestselling author of Courage Is Calling , to tackle the one thing standing between you and your potential: fear. Why should you listen? Because fear is the root cause of procrastination, self-doubt, and the endless excuses that keep you stuck. Ryan re...
Dec 26, 2024•1 hr 16 min•Ep. 1236
Today we are bringing back one of our all-time favorite episodes with James Altucher. Dave sits down with James, an entrepreneur, bestselling author, and master experimenter, to uncover why the 10,000-hour rule might just be holding you back. Instead of grinding your way to expertise, James reveals his 10,000 Experiment Rule—a game-changing approach to mastering any skill faster than you thought possible. From comedy stages to boardrooms, James has redefined success through relentles...
Dec 24, 2024•57 min•Ep. 1235
Can you use hate to make the world a better place? Daryl Davis, a world-class jazz musician, didn’t just confront hate—he dismantled it. By sitting down with over 200 Ku Klux Klan members, he inspired them to leave their robes behind. But this isn’t just a story about racism or redemption; it’s a story about the incredible power of human connection and the lessons it holds for all of us. In this special episode, Dave explores how Daryl turned impossible conversations into transforma...
Dec 19, 2024•2 hr 30 min•Ep. 1234
Is AI About to Replace Your Doctor? Or Save Your Life? The tools that are reshaping healthcare will redefine medicine—and your life—in ways you’ve never imagined. Will artificial intelligence and regenerative therapies like stem cells and exosomes make doctors obsolete? Or will they finally unlock the secrets to living to 180? In this episode, Dave sits down with Dr. Pradeep Albert, a leader in regenerative medicine and AI-driven imaging, to explore the intersection of technolo...
Dec 17, 2024•1 hr 21 min•Ep. 1233
Most people don’t think about their liver until it’s too late. In this episode, Dave sits down with Siggi Clavien, founder of de-liver-ance® & The Liver Clinic, to uncover the hidden superpowers of the body’s most underrated organ: the liver. This is a deep dive into why your liver is the ultimate game-changer for your energy, brain power, and longevity. Siggi reveals groundbreaking insights on reversing fatty liver disease, boosting detoxification, and harnessing the l...
Dec 13, 2024•1 hr 9 min•Ep. 1232
Will the next nuclear bomb be AI Superintelligence? The intelligence we’re building will reshape the world in ways we never imagined—for better or worse? But more importantly, what side will humanity take? In this episode, Mo Gawdat, bestselling author of Scary Smart and former Chief Business Officer of Google X, joins Dave to tackle the profound challenges and opportunities artificial intelligence presents. This isn’t about dystopian robots or tech hype—it’s about redef...
Dec 12, 2024•24 min•Ep. 1231
Can Happiness Really Be Engineered? Mo Gawdat Says Yes—And Here’s How. I know what you’re thinking… ANOTHER episode on happiness? Haven’t we heard it all before? This one’s different. The code is cracked, and you’re about to learn exactly how it works. Joining us today is Mo Gawdat, bestselling author of Unstressable and former Chief Business Officer of Google X. Mo sits down with Dave to deliver a practical, science-backed approach to hacking your mind and body for lasting joy...
Dec 10, 2024•1 hr 7 min•Ep. 1230
Does Calorie Restriction Even Work? What About the Carnivore Diet AND Fruit? Today we are excited to have Paul Saladino join us for a masterclass on food and diets. Dr. Saladino dives into the evolution of keto and carnivore diets, cutting through trends to focus on lasting health impacts. Dr. Saladino, widely recognized as CarnivoreMD, shares how his own diet shifted to include fruit and honey alongside animal-based nutrition, and why metabolic flexibility—not rigid rules—leads to b...
Dec 05, 2024•2 hr 43 min•Ep. 1229
What are the oral hygiene tips that could save your life? Dave Asprey sits down with one of the most popular guests on the show, Naveen Jain, founder and CEO of Viome Life Sciences, to explore how your oral microbiome influences not just your dental health but your entire body. Naveen reveals groundbreaking insights into how imbalances in oral bacteria can trigger chronic inflammation, heart disease, and even cancer—and how understanding your unique microbiome can help prevent these risks...
Dec 03, 2024•1 hr 11 min•Ep. 1228
Is this the missing link in fertility? The vaginal microbiome could be the most overlooked factor in optimizing women’s health, from fertility and hormonal balance to preventing infections and improving quality of life. In this groundbreaking episode, Dave Asprey talks to Priyanka Jain, co-founder and CEO of Evvy, about how understanding and improving the vaginal microbiome can transform women’s health outcomes. Priyanka shares how Evvy is advancing women’s health through cutting-ed...
Nov 28, 2024•1 hr 12 min•Ep. 1227
Is alcohol losing its grip as the go-to social drink? Enter kava—a centuries-old Polynesian plant that’s gaining global recognition for its ability to relax the mind, elevate mood, and enhance social connection without the toxic effects of alcohol. Kava, particularly in the form of TRU KAVA, is a psychoactive yet non-intoxicating drink that offers the perfect balance of calm focus and mental clarity. In this episode, Dave Asprey welcomes Cameron George, founder of TRU KAVA, to discu...
Nov 26, 2024•1 hr 7 min•Ep. 1226
Have we finally discovered the key to youthful energy, longevity, and cellular health? In this episode, Dave Asprey sits down with Dr. Anurag Singh, Chief Medical Officer at Timeline Nutrition and a leading expert on mitochondrial health, cellular regeneration, and anti-aging science. With over 20 years of research, 50 clinical trials, and 15 patents under his belt, Dr. Singh unpacks the groundbreaking science behind Urolithin A, a revolutionary postbiotic that boosts mitochondrial functi...
Nov 22, 2024•59 min•Ep. 1225
Are exosomes the planet’s ultimate healing tool?! In this episode, Dave Asprey sits down with Harvard-trained physician Dr. Edward Park to explore the groundbreaking science of exosomes. Dr. Park, a pioneer in regenerative medicine and author of Exosomes: Songs of Healing , explains how these tiny cellular messengers are revolutionizing health and longevity by bypassing the limitations of stem cells. BUT this episode isn’t just about cutting-edge science. Dr. Park also shares profou...
Nov 21, 2024•1 hr 11 min•Ep. 1224
Is biohacking your sweat the secret to vitality? Dave Asprey dives into the transformative world of infrared saunas with Connie Zack, founder of Sunlighten and a 25-year innovator in the space. Together, they uncover how targeted light and heat therapy can unlock unparalleled health benefits, from detoxing heavy metals to energizing your body at the cellular level. Here’s what you’ll learn in this episode: • Why infrared saunas excel at detoxing heavy metals and toxins •...
Nov 19, 2024•50 min•Ep. 1223
What if you could command any room and set boundaries without saying a word? Dave Asprey sits down with Kasia Urbaniak, founder and CEO of The Academy—a trailblazing school where women learn the true principles of influence and authority. Kasia brings a unique and dynamic perspective, drawing on nearly two decades of experience that includes working as a professional Dominatrix, practicing Taoist alchemy in one of China’s oldest female-led monasteries, and earning certifications across di...
Nov 14, 2024•2 hr 46 min•Ep. 1222
Is unlocking the full potential of your brain even possible, or just a myth from the movie Limitless ? In this eye-opening episode, neuroscientist and author Dr. Mithu Storoni joins Dave to dive deep into the science of brain optimization for hyper-efficient work performance. Together, they break down the surprising roles of astrocytes in supporting neurons, the influence of the brain’s “blue dot” region (the locus coeruleus) on focus and mental clarity, and how harnessing neuroplasticity ...
Nov 12, 2024•1 hr 24 min•Ep. 1221
What if the keys to an extraordinary life lie in choices most people wouldn’t dare to make? In this iconic, unearthed episode, best-selling author and performance pioneer Tim Ferriss joins Dave Asprey to spill the unfiltered truth on smart drugs, insect protein, and the surprising links between sex, creativity, and high performance. They dig into cutting-edge topics still sparking curiosity today: the calculated risks and rewards of smart drugs, the future-forward benefits of insect...
Nov 07, 2024•34 min•Ep. 1220
What if everything you believe about happiness is wrong? In this episode, Harvard professor and world-renowned happiness expert Arthur Brooks joins Dave Asprey to unlock the secrets of real happiness, revealing the science behind joy, resilience, and lasting fulfillment. As a bestselling author and co-author with Oprah Winfrey of Build the Life You Want , Arthur has spent decades helping people rethink happiness through a blend of psychology, neuroscience, and ancient wisdom. Togeth...
Nov 05, 2024•1 hr 18 min•Ep. 1219
Explore the science and potential of hypnosis as Dr. David Spiegel, Stanford’s leading expert in mind-body medicine, joins Dave Asprey to reveal how hypnosis can radically enhance cognition, mental clarity, and resilience. In this episode of The Human Upgrade , you’ll learn how hypnosis influences the brain’s most vital networks, including the default mode network and executive control, to break mental barriers and amplify focus, perception, and healing. Discover how hypnosis, unlike tradi...
Oct 31, 2024•1 hr•Ep. 1218
Unlock the mastermind secrets to cognitive enhancement as Dave Asprey shares his ultimate brain-boosting biohacks in this powerful episode of The Human Upgrade . Discover how Dave elevated his IQ, reversed Asperger’s, and overcame brain fog through advanced neurofeedback, BDNF-boosting supplements, mitochondrial enhancers, and the power of the groundbreaking 40 Years of Zen program. Explore revolutionary techniques, from ancient meditation practices to modern nootropics and smart drugs, al...
Oct 29, 2024•1 hr 20 min•Ep. 1217
Unlock the secret to cellular detox and discover how to cleanse your body from the inside out with Dave Asprey and Jessica Berman in this episode of The Human Upgrade . Explore cutting-edge detox strategies using phosphatidylcholine, Tudca, and butyrate, three powerful molecules designed to remove toxins, microplastics, and endocrine disruptors from your system. Jessica, co-owner of BodyBio, reveals how these products support not just detoxification, but also optimize mitochondrial functio...
Oct 25, 2024•1 hr 4 min•Ep. 1216
Step into the future of sports performance with The Human Upgrade as Dave Asprey and Aron D’Souza, founder of the Enhanced Games, uncover the controversial world of steroids, gene therapy, peptides, and human enhancement. In this groundbreaking episode, they explore how athletes can push the boundaries of physical and mental performance by embracing cutting-edge science once banned by traditional sports bodies like the Olympics. Discover why the Enhanced Games are redefining fairness in at...
Oct 24, 2024•1 hr 8 min•Ep. 1215
Unlock the power of continuous glucose monitoring (CGM) and transform your health in this eye-opening episode with Dave Asprey. Discover why tracking your blood sugar 24/7 isn’t just for diabetics—it’s the key to unlocking peak health, optimizing your metabolism, and preventing chronic diseases. Joined by Levels founder and biohacker Josh Clemente, Dave dives into the real science behind CGMs and how they provide unparalleled insights into how your diet, sleep, and exercise affect your blo...
Oct 22, 2024•1 hr 24 min•Ep. 1214
Get ready to discover the true superfoods that can transform your health—starting with spirulina and chlorella. In this dynamic and thought-provoking episode, Dave Asprey welcomes Catharine Arnston, founder of ENERGYbits, to dive deep into the world of algae and its incredible potential to boost energy, detox the body, and support longevity. First, we challenge the myths around trendy “superfoods” and reveal why algae, particularly spirulina and chlorella, reign supreme for mitochondrial h...
Oct 18, 2024•59 min•Ep. 1213
Today, we’re diving into the age old question, what is the purpose of your life? We chat about the science behind emotional intelligence with Dr. John Demartini, creator of the groundbreaking Demartini Method. In this thought-provoking episode, Dr. Demartini reveals how his unique approach to personal development and emotional mastery can help you uncover your highest values and transcend emotional chaos. We explore how the quality of the questions you ask shapes the quality of your life, ...
Oct 17, 2024•1 hr 10 min•Ep. 1212
Today, we’re unlocking the full potential of your brain—starting with Bryan Johnson’s Blueprint for longevity and brain optimization. We’re revisiting our conversation with Bryan, the creator of the Don’t Die movement (among many other things), to explore how his groundbreaking approach to brain health and biohacking is reshaping the future of longevity. First, we dive into Bryan’s mission to make brain monitoring as easy as tracking blood glucose, using his Blueprint protocol to mea...
Oct 15, 2024•1 hr 22 min•Ep. 1211
