For a decade, Dave Asprey, “the father of biohacking,” elevated what you knew about the capabilities of your mind and body across a thousand episodes of Bulletproof Radio. Now, he’s evolving it even further in his plan to upgrade humanity. You’re invited to expand your knowledge, explore your own performance and embrace possibility with The Human Upgrade™.
You’ll meet bright thinkers and radical doers who push the boundaries of science, technology, personal development, and human performance in every way imaginable. You’ll learn from experts around the world who elevate what it means to be human.
Every guest you listen to, every topic you learn about, every new idea you discover on this podcast moves you forward.
Join The Human Upgrade™ with Dave Asprey on this next evolution to upgrade your mind, body and life.
Every 13 minutes, a woman dies of breast cancer. And this unnecessary epidemic affects men, too. Today, you’ll hear a fascinating interview with a woman on a mission to empower people to do more than just survive breast cancer, but become radiantly healthy; Dr. Toni Galardi. She's not only a holistic psychotherapist with a PhD in psychology, but a remarkable individual who cured herself of breast cancer. Dr. Galardi is a prolific author with three books under her belt, including her latest...
In today's episode I’m reuniting with someone who has had a profound impact on my journey as a biohacker, Rollin McCraty, the director of research at the HeartMath Institute. Rollin specializes in the physiology of emotion, and his research explores how emotions impact cognition, behavior, health, and global interconnectivity. I first encountered Rollin nearly two decades ago during my tenure at the Silicon Valley Health Institute. Back then, I was a young enthusiast, navigating the in...
In today’s episode, we tackle longevity, exploring workouts optimized for hormones, and dive deep into a crucial quality we all need a bit more of—resilience (or as I like to call it, equanimity). It's about more than just being tough; it's about the ability to maintain your chosen mental and emotional state, no matter what life throws your way. I’m excited to introduce Tony Horton, a name many of you will recognize. We both are passionate about the journey to self-improvement, albeit via differ...
Who doesn’t want more radiant skin? Not only is our skin our largest organ, but it influences our confidence and how we connect with others. That’s why I'm excited to be sitting down at my Austin, Texas studio with skin expert and longtime friend, Rachel Varga. Rachel is a double board-certified aesthetic nurse specialist, having performed over 20,000 procedures since 2011. She was one of the first to combine functional slow-aging techniques, biohacking, and modern medical aesthetics—teach...
In today's episode, we're joined by Dr. Gad Saad, a professor of marketing at Concordia University's John Molson School of Business. More significantly, Dr. Saad has spent a decade as the research chair in evolutionary behavioral sciences and Darwinian consumption. Beyond his extensive research and academic accolades, Dr. Saad reaches out to a broader audience, sharing his insights through his popular blog, YouTube channel, and podcast. As someone deeply interested in challenging harmful ideolog...
Today, we welcome back a guest from the early days of this podcast, fellow former vegan and esteemed researcher and scientist, Chris Masterjohn. Chris Masterjohn earned his PhD in Nutritional Sciences from the University of Connecticut, and has worked as a postdoctoral research associate and Assistant Professor of Health and Nutrition Sciences. In 2016, he transitioned to entrepreneurship. These days, Chris conducts independent research, consults, develops information products, and creates...
If you struggle with retaining sharp focus or have been diagnosed with ADHD or other conditions that impede your brain from functioning at its optimal level, this is the podcast episode for you. We learn about a (literally) out-of-the-box solution to attention training—video games. Yes, you read that right. Our guest today, Dr. Adam Gazzaley, holds an M.D. and Ph.D. in Neuroscience from Mount Sinai School of Medicine and completed Neurology residency at the University of Pennsylvania, followed b...
I am a sucker for supplements with extensive and impressive research to prove their biohacking benefits, and OMNi-BiOTiC is one of them. Research studies by OMNi-BiOTiC show a 50% or 70% improvement in things like brain function, insulin sensitivity, and detoxification which is really compelling—and exactly why we have Hannah Kleinfield on the show today. Hannah Kleinfeld is the Chief Operating Officer of Allergosan USA, the U.S. joint-venture partner of Institut Allergosan, a global leader in m...
Today's episode is with my friend Susan Bratton, who is an intimacy expert with 20 years of experience. She runs a publishing company called Better Lover, and has a supplement company called The 20. Her expertise is in ageless sexuality, sexual biohacking, libido supplementation, and sexual regenerative therapies that roll back the clock on aging. Whether you're a man or a woman, you’ll learn the specific things you can do to change the performance, the shape, the sensitivity, and the longevity ...
So much of your reality is determined by your brain, and if you have dealt with chronic disease or mental health struggles like me, it can feel like there’s something wrong with you. But, it’s probably not you. It’s probably a brain problem. Today’s guest, Dr. Brandon Crawford, is here to provide some hope and some answers. Dr. Brandon Crawford is a board-certified Developmental Functional Neurologist, driven by training from esteemed minds in chiropractic, functional neurology, and ...
If you're frustrated with a system prioritizing profit over societal well-being, this episode is pivotal. Today, we dive deep with Ivor Cummins, a Dublin-based biochemical engineer with a knack for simplifying complex topics. Based on his personal history of insulin resistance and health struggles, he was able to self-heal through nutrition and a low carb diet. In this conversation, we examine the nexus of insulin resistance, heart health, and the current medical system’s failure to diagno...
You've heard lots on this show about biohacking, longevity, and how to help your brain and body perform better. But what if you could do the same things for your pet? I've spent most of my life with pets and/or farm animals so I’m thrilled to have my longtime friend, Dr. Gary Richter, America's favorite veterinarian, here to tell you all you need to know about biohacking for your pets. Dr. Gary Richter, DVM, is a distinguished veterinarian, international bestselling author of The Ultimate Pet He...
Our guest is Jack Dell’Accio, the CEO of Essentia. Essentia has been working on non toxic, organic mattresses for 20 years. Of most importance to Jack is the impact of restorative sleep in terms of recovery from disease, prevention of disease, longevity, and performance. He's funded a bunch of research on sleep quality and has worked directly with health gurus including myself, professional athletes, various teams in the NBA, NFL, MLS, and over 25% of active NHL players on creating healthy...
The environment you live in has the most profound impact on your health and wellbeing, but are you aware of the toxins and pollutants we’re surrounded by on a daily basis? That is why today’s episode is so important. We talk about toxins that are overlooked in your house and what you can do about them. Our guest is Ryan Blaser, the founder and CEO of Test My Home, an environmental company dedicated to improving your health by changing the environment around you. As a functional medic...
Alan Graves is the CEO of Do Not Age, a UK-based longevity company, and he’s been fully immersed in the biohacking space since 2019. In that short time, he’s become a leader in supplementation and expanded his curiosities—even as far as outer space. We talk about his preparation for an upcoming Virgin Atlantic flight to the stars, and how he plans to protect his human form in such an environment. We also touch on our dieting journeys—from veganism to all-meat and everything in between, ride the ...
Dialing in from Dubai, today, we hear from global inventor and investor, Saba Yussouf, about how to position STEM technologies – science, technology, engineering, and math – to prevent infection, treat water, and even fight 100-year problems like climate change. Half business leader and half scientist, herself, she is a futurist, versed in the fine-tuned details of STEM, and putting it all to work through her disruptive investment record around the world. We learn about nanobubbles and their ben...
IN THIS EPISODE OF THE HUMAN UPGRADE™, we revisit a conversation Dave had with Magnus Lygdbäck in Spring of 2022. You’ll learn how a trainer of superheroes and superstars combines core principles of fitness, nutrition, structure and balance. Magnus Lygdbäck, a Swedish health and wellness expert, entrepreneur, and lifestyle coach, joins the show to discuss powering your life in ways that most benefit your health and energy. For more than 20 years, he’s trained some of the world’s most recognizabl...
Today, we’re joined by second-time guest, Dr. Caroline Leaf, to talk about helping kids clean up their mental mess and be more resilient—all based on research from her latest book, How to Help Your Child Clean Up Their Mental Mess. In this episode, Dr. Caroline Leaf shares the best ways for parents to help their kids understand their emotions and build better habits. Dr. Leaf conducts ongoing research and clinical trials in the field of psychoneurobiology in order to improve mental health interv...
IN THIS EPISODE OF THE HUMAN UPGRADE you’ll learn how to recognize your own sh*t and be a better partner in relationships. Want a sustainable partnership? Communicate and apologize; fight without fighting; identify codependent behavior (your own); and manage jealousy (also your own). This conversation gets into how you can let go of unrealistic ideals of how you think love and relationships should be and live fully in the present. You’ll also get tips on how to be emotionally respons...
Dr. Myles Spar joins Dave Asprey to discuss the benefits of Calroy Health Sciences products, Arterosil and Vascanox, focusing on their impact on athletic performance, cardiovascular health, and sexual function. They explore the science behind nitric oxide and hydrogen sulfide, emphasizing their roles in vasodilation, antioxidant activity, and overall health. The episode also covers the importance of quality supplementation, personalized medicine, and working collaboratively with healthcare providers.
Today's episode is a special intervention episode where I work with a member of the Upgrade Collective, my mentorship and membership group, to help them get closer to achieving their health goals. This conversation is all about investigating member Nadya Green’s struggle to lose weight despite following a low carb diet and cycle syncing her eating habits. Nadya, originally from Russia, has spent her life pursuing an international career in the energy sector. She has worked as an engineer a...
Our guest today is a legendary thinker, author, and philosopher. Ken Wilber has spent decades understanding how humans are all interconnected with each other, decoding through dozens of beautifully written books, how we fit into the greater, massive, picture that is the expanding universe. He's an absolute pioneer, a visionary, and that barely scratches the surface of his work. He joins Dave to outline his newest book—Finding Radical Wholeness: The Integral Path to Unity, Growth, and Delights—an...
In this episode of The Human Upgrade you’ll meet a holistic neurosurgeon who’s evolving spine care away from cutting. Dr. Marcella Madera’s integrative approaches to spine problems pair science with holistic healing modalities. This means way better healing for you. Dr. Madera’s innovations in spine treatments include the “Aqua Method,” where photobiomodulated platelet rich plasma meets functional tissue mobilization and movement. You’re going to get exciting new informat...
In this episode of The Human Upgrade you’ll find out how to harness the power of your inner voice to ease anxiety, improve physical and mental health, and deepen your relationship with others. “The mind is flexible, if we know how to bend it,” says psychologist and award-winning professor Ethan Kross, Ph.D., founder of the Emotion & Self Control Laboratory at the University of Michigan. He’s one of the world’s leading experts in controlling the conscious mind. He studies the ways in wh...
Today, on The Human Upgrade, we talk to Steve Revelli about the long history and bright future of using silver nanoparticles as a biohacking silver bullet. Steve's background is in science and education, now serving as the QA Manager at American Biotech Labs, LLC, the brand which produces Silver Biotics—a long-time resident of my own medicine cabinet. The conversation covers the difference between pathogenic bacteria and probiotics, how silver under a concentration of 40 parts per million ...
Today, we're delving deep into the importance of dirt, not just as soil beneath our feet, but as a key factor in regenerative agriculture and biohacking. Our guest, Andrea Bemis, is an expert in sustainable organic farming and a passionate advocate for nurturing healthy babies and children. Together, we explore the power of the family dinner and the significance of avoiding harmful chemicals and additives in the food we provide for our kids. Andrea Bemis, the brilliant mind behind the farm-to-ta...
Today, a dear friend of the show and someone who's disrupted a huge part of the healthcare industry joins us for an informative chat on the critically important oral microbiome—and from a wider perspective—how and why the human body gets sick. Naveen Jain, founder of Viome—a data company that’s changing the world of health and wellness—goes deep on the latest in anti-aging, what's going on in your mouth and how that affects everything else in your body, the perils of mouthwash, the future ...
IN THIS EPISODE OF THE HUMAN UPGRADE™️... Sadhguru, a yogi, mystic, visionary and spiritual master who spreads wisdom around the world, clarifies the meaning of karma (no, it’s not a checklist of good and bad deeds) and explains how much you’re in charge of your own karma. His most recent book, “ Karma: A Yogi’s Guide to Crafting Your Destiny ,” breaks down the ways in which karma frames our lives. “It’s time to unpack the most overused, abused and yet indispensable world in t...
IN THIS EPISODE OF THE HUMAN UPGRADE ™ ... “Americans are the unhappiest they have been since the Great Depression,” says Dr. Daniel Amen. But he’s determined to change that. He’s a physician and double board-certified psychiatrist who looks at happiness as a brain function. After studying more than 200,000 brain scans of people from 155 countries, Dr. Daniel Amen discovered five primary brain types and seven neuroscience secrets that influence happiness. “I wanted to spend my time and ene...
If you have all sorts of unexplained health problems in your home, where you work, or where you go to school, symptoms can be very different. One person's gaining fat, another person's always tired, other people have dark circles, emotional irregularity, sudden weight gain, onset of allergies that no one can explain, on and on. In the episode today, you learn the smarter, not harder, ways to deal with toxic mold exposure in your environment from one of the world’s leading experts on the matter.&...