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Longevity Junky

Buck Joffrey & Nikki Leighshows.acast.com
TIME TO GET YOUR FIX! Longevity Junky is a compelling and accessible new podcast that works for all longevity enthusiasts, whether you’re a hardened scholar who craves detailed science or a relative newcomer to this fascinating and quickly evolving world. Dr. Buck Joffrey, MD, is a former neurosurgeon, successful entrepreneur, and self-described health-conscious hedonist. Nikki Leigh is a jet-setting actress influencer with 6M followers and is the OG Longevity Junky. They’re good friends and willing guinea pigs for all longevity-related experiments. From hallucinogens to full body MRIs, micro-dosing Cialis to tech, exercise, and diet to mindfulness, they’re on a voyage of discovery, meeting the best experts in each space, learning and sharing their experiences, and giving listeners actionable tips on how to live a longer, happier life. Let’s face it: reducing our biological age, extending our lifespan, and increasing happiness are pretty universally appealing ideas. 

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Episodes

144: The Science of Forgiveness with Dr. Robert Enright

Can forgiving others actually make you healthier? Dr. Robert Enright, the pioneer of forgiveness science, reveals how forgiveness transforms emotional and physical health. He breaks down the damaging effects of unforgiveness—like high blood pressure and anxiety—and explains how his four-phase forgiveness model is improving lives in schools and hospitals. From self-forgiveness to emotional resilience, this episode redefines forgiveness as a powerful path to mental and physical well-being. Learn m...

Jul 07, 202545 minSeason 1Ep. 44

143: Dr. Dave Rabin on Psychedelics, Stress, and Neuroplasticity

Can stress be hacked with vibrations? Psychiatrist and neuroscientist Dr. Dave Rabin joins Nikki Leigh and Buck Joffrey to reveal how chronic stress disrupts health—and what you can do about it. From psychedelics to wearable tech like Apollo Neuro , Dr. Rabin explains how vibration therapy is being used to regulate the nervous system, boost emotional resilience, and support long-term mental health. They dive into the latest neuroscience behind stress management, integrative psychiatry, and the e...

Jun 30, 202555 minSeason 1Ep. 43

142: How Medicine Wronged Women’s Health with Dr. Pamela Peeke

Women's health has been misunderstood—and often ignored—for decades. In this episode, Dr. Pamela Peeke joins Buck Joffrey and Nikki Leigh to set the record straight. From the outdated belief that “women are just small men” to the shocking truth about flawed medical research, Dr. Peeke reveals what every woman needs to know about body composition, hormone therapy, emotional eating, and chronic stress. Her “Mind, Mouth, and Muscle” approach offers a powerful framework for lasting change. Learn mor...

Jun 23, 20251 hr 8 minSeason 1Ep. 42

141: NFL to Science - Dr. Ryan Rosner on Muscle, Metabolism, and the Molecular Future of Aging

Dr. Ryan Rosner went from the NFL to the lab—now he's advancing some of the most promising developments in aging science. In this episode, we talk about his transition into molecular aging research and the science behind hypoxia, plasmid therapy, and follistatin’s role in muscle and metabolic health. We cover key topics including cellular resilience, epigenetic rejuvenation, gene therapy, and emerging applications of plasmid technology. Rosner also shares insights into ongoing clinical trials, h...

Jun 16, 202550 minSeason 1Ep. 41

140: How Well Do You Know Longevity?

Welcome to Longevity Junky's inaugural trivia show, Longeopardy! First-time game show host Dr. Buck Joffrey is joined by contestants Nikki Leigh and Madisyn Shipman in a fun and informative game centered around health, wellness, and anatomy. Follow Madisyn Shipman: Instagram @madisynshipman TikTok @itsmadisynshipman - Let us know what kind of trivia topics you would like us to do next. Send us a message at: www.longevityjunky.com Follow us on social media: Instagram: https://www.instagram.com/lo...

Jun 09, 202533 minSeason 1Ep. 40

139: Health Gone Wrong | Reading Reddit Stories

What do you do when your husband cheats on you… while you’re battling cervical cancer? Would you trust a babysitter who gave your toddler melatonin without asking? And how far is too far when it comes to dietary boundaries? In this episode of Longevity Junky, Nikki Leigh and Dr. Buck Joffrey unpack Reddit stories that expose the messy, complicated realities of health in everyday life. From HPV-related cancer and kidney infections to parenting fails and nutrition drama, they break down the health...

Jun 02, 202550 minSeason 1Ep. 39

138: Evidence-Based Hyperbaric Oxygen Protocol for Reversing Cellular Aging

What if you could slow aging, repair cells, and boost your brain—all by breathing oxygen under pressure? Dr. Shai Efrati joins Longevity Junky to unpack the science and protocols behind hyperbaric oxygen therapy (HBOT). This isn’t just oxygen—it’s precision medicine. We dive deep into how HBOT enhances oxygen delivery to tissues, triggers cellular repair, and may even lengthen telomeres. From cognitive enhancement to VO2 max gains in athletes, HBOT’s potential spans performance, recovery, and ag...

May 26, 20251 hr 13 minSeason 1Ep. 38

137: Fasting Benefits Without the Fasting

What if you could trigger the benefits of a 36-hour fast—without skipping a single meal? Dr. Chris Rhodes, nutritional biochemist and founder of Mimio, joins Nikki and Buck to unpack the science behind fasting mimetics. Discover how specific molecules can mimic the effects of prolonged fasting, from activating autophagy to improving insulin sensitivity, reducing inflammation, and suppressing appetite. Plus, we dives into weird wellness history with Lord Byron's vinegar obsession and how apple ci...

May 19, 20251 hrSeason 1Ep. 37

136: Can Stress Be Anti-Aging? | Dr. Sharon Bergquist

Dr. Sharon Bergquist—Harvard-trained physician, Emory researcher, and author of The Stress Paradox —joins Longevity Junky to flip the script on everything we thought we knew about stress. Discover how good stress (yes, it exists!) can supercharge your cellular health, build resilience, and even slow down biological aging . From cold exposure and intermittent fasting to emotional challenges that light you up, this episode explores the science of hormesis and the “Goldilocks zone” of stress for op...

May 12, 202558 minSeason 1Ep. 36

135: Reversing Alzheimer’s Through Diet and Lifestyle with Dr. Dean Ornish

Can Alzheimer’s be reversed without drugs? Dr. Dean Ornish says yes—and he has the clinical data to prove it. In this episode of Longevity Junky , Nikki and Buck sit down with the father of lifestyle medicine to explore a groundbreaking study showing how diet, exercise, stress reduction, and community can actually stop—or even reverse —early-stage Alzheimer’s. From the science of neuroplasticity to the power of social support, this conversation is packed with insight, hope, and practical steps a...

May 05, 202555 minSeason 1Ep. 35

134: Unhinged Medical Stories from Reddit

Get ready for some of the wildest, most jaw-dropping medical stories ever shared on Reddit. From ER scammers faking injuries for pain meds… to DIY tracheotomies, exploding intestines, and near-fatal sex injuries—these real-life cases are as unbelievable as they are horrifying. Join Dr. Buck Joffrey and Nikki Leigh as they break down these totally unhinged Reddit stories with useful medical insights and some humor along the way. - Have a wild medical story from Reddit we should cover next? Submit...

Apr 28, 202549 minSeason 1Ep. 34

133: Don't Bury Me, Freeze Me - The New Billionaire Obsesson with Cryonics

What if preserving your body after death wasn’t science fiction—but science in progress? In this mind-expanding conversation, James Arrowood of Alcor dives deep into the science and ethics of cryonics, explaining how ultra-cold preservation of human tissue could transform the future of medicine, organ banking, and even space travel. Learn how cryonics works, how Alcor operates as a non-profit, and what it means for our understanding of consciousness, trauma medicine, and longevity. We explore th...

Apr 21, 20251 hr 7 minSeason 1Ep. 33

132: How AI is Transforming the Way We Eat

Discover how AI is revolutionizing personalized nutrition, diet tracking, and longevity in this episode of Longevity Junky. Caltech-trained physicist and AI entrepreneur Dr. Dmitriy Richard Starson reveals the tech behind his groundbreaking platform that analyzes your meals through photos and voice—no more tedious logging. Learn how AI can tailor your food choices, improve metabolic health, and even help doctors deliver better care. Learn more about Dr. Dmitriy Richard Starson & Passio: http...

Apr 14, 202558 minSeason 1Ep. 32

131: Can You Die of Boredom?!

Is boredom slowly killing you? Cognitive neuroscientist Dr. James Danckert joins Longevity Junky to break down the science of boredom—what it does to your brain, how it’s linked to depression, addiction, even heart disease, and why your response to boredom could affect your longevity. Plus, why some people shock themselves out of boredom (literally). Learn more about Dr. James Danckert: https://www.jamesdanckert.com/about - Bioxcellerator is offering our listeners special discounts and offers on...

Apr 07, 202553 minSeason 1Ep. 31

130: What Do Microplastics Do to Your Health?

Did you know microplastics could be silently damaging your hormones, fertility, and heart health? In this explosive episode, Dr. Leonardo Trasande—NYU professor, bestselling author, and global leader in environmental pediatrics—joins Buck and Nikki to reveal how these invisible plastic particles are infiltrating our bodies through food, water, and even air. Learn how microplastics disrupt your endocrine system, spike inflammation, and accelerate aging—and what you can actually do to reduce your ...

Mar 31, 20251 hr 5 minSeason 1Ep. 30

129: Which Longevity Supplements Should You Take?

What supplements do two longevity junkies actually take? In this episode, Dr. Buck Joffrey and Nikki Leigh reveal their personal daily supplement stacks—the real-life regimens they follow to stay sharp, healthy, and (hopefully) young forever. But here’s the kicker… not all supplements on store shelves are what they seem. Buck shares the shocking results of a study revealing that nearly half of herbal supplements don’t even contain what they claim. Nikki and Buck break down how to cut through the...

Mar 24, 20251 hrSeason 1Ep. 20

128: Is Polyamory Good for Your Health?

What if rethinking relationships could unlock deeper connection, emotional well-being, and even longevity? In this episode of Longevity Junky, Nikki and Buck sit down with Dr. Joli Hamilton—research psychologist, certified sex educator, and relationship coach—to explore the world of consensual non-monogamy, jealousy, and alternative relationship dynamics. Dr. Joli shares her personal journey from monogamy to a cohabiting triad, the emotional complexities of jealousy, and how embracing unconventi...

Mar 17, 20251 hr 14 minSeason 1Ep. 28

127: Lesley Paterson - Triathlon World Champion to Oscar Winner

Oscar-winning screenwriter and five-time world champion triathlete—Lesley Paterson doesn’t just break barriers; she obliterates them. From pushing through brutal endurance races to fighting for All Quiet on the Western Front, her mindset is an absolute masterclass in resilience. We dive into her elite fitness strategies, how she overcame chronic Lyme disease, and the shocking connection between metabolic health and cancer. Learn more about Lesley Paterson: https://www.lesleypaterson.com/ Bioxcel...

Mar 10, 20251 hr 4 minSeason 1Ep. 27

126: The Billion-Dollar Race to Defy Aging – David Dror on Longevity Investment

In this episode of Longevity Junky , Buck Joffrey and Nikki Leigh sit down with David Mark Dror , author of Investors in Longevity , to explore the multi-billion-dollar investments driving longevity breakthroughs . Discover how Jeff Bezos, Peter Thiel, and major biotech firms are funding research in: - Gene therapy and cellular reprogramming to slow aging - AI-driven drug discovery for life extension - Regenerative medicine and stem cell therapy Plus, we answer a listener’s burning question: Wha...

Mar 03, 202552 minSeason 1Ep. 26

125: Bigger, Stronger, Faster - The Science of Muscle Growth with Dr. Mike Israetel

How do you maximize muscle growth? What’s the optimal way to train for hypertrophy? Dr. Mike Israetel, fitness and performance expert, joins Buck Joffrey and Nikki Leigh to break down the science of building muscle—from protein timing to training volume and even future muscle-enhancing drugs. Plus, insights on sleep, recovery, and how genetics impact gains. Learn more about Dr. Mike Israetel: https://www.instagram.com/drmikeisraetel/?hl=en Bioxcellerator is offering our listeners special discoun...

Feb 24, 20251 hr 24 minSeason 1Ep. 25

124: Does Red Light Improve Mitochondrial Health?

Buck and Prof Glen Jeffery dive deep into the science of red light therapy, revealing how it boosts mitochondrial function and potentially slows aging. He shares groundbreaking insights from clinical trials, showing how red light can recharge cellular energy and improve vision health. We get into practical tips on using red light therapy—where to get it, when to use it, and what to watch out for in devices. Learn more about Prof Jeffery: https://profiles.ucl.ac.uk/7465-glen-jeffery Bioxcellerato...

Feb 17, 202542 minSeason 1Ep. 24

123: How Stem Cells Saved UFC Champion's Career with T.J. Dillashaw

What happens when a UFC champion turns his focus from fighting in the cage to fighting aging? Former two-time UFC bantamweight champion TJ Dillashaw joins Nikki and Buck for a deep dive into stem cell therapy, peak performance, and biohacking longevity . TJ shares his experience with BioAccelerator’s advanced stem cell treatments , how they’ve impacted his injuries, and why he’s all-in on cutting-edge health optimization. From nutrition, fasting, and sleep hacks to training smarter—not just hard...

Feb 10, 202559 minSeason 1Ep. 23

122: The Science of Laughter & Longevity with Ed Crasnick

Emmy-winning writer and comedian Ed Crasnick joins Buck and Nikki to explore the connection between humor and health. From his work on Curb Your Enthusiasm to his passion for mental health advocacy, Ed shares how laughter reshapes our minds, reduces stress, and even boosts longevity. Plus, Nikki and Buck dive into Reddit’s latest medical misadventure and share their personal experiences with stem cell therapy. Learn more about Ed Crasnick: https://www.imdb.com/name/nm0186553/ Bioxcellerator is o...

Feb 03, 20251 hr 5 minSeason 1Ep. 22

121: Why We Got Stem Cell Therapy in Colombia

Join Buck and Nikki as they dive headfirst into the future of regenerative medicine. In this episode, they’re in Medellín, Colombia, where they didn’t just explore cutting-edge stem cell therapy at BioXcellerator—they experienced it themselves. Alongside CEO Eric Stoffers, they uncover how these groundbreaking treatments are transforming lives, from autoimmune diseases to orthopedic challenges and beyond. Hear their personal stories, bold insights, and practical takeaways to help you elevate you...

Jan 27, 20251 hr 14 minSeason 1Ep. 21

120: How to Find Your Purpose to Live Longer

Can a sense of purpose truly extend your life? In this episode of Longevity Junky, Buck and Nikki sit down with renowned psychologist Dr. Michael Mantz to explore the powerful connection between purpose, health, and longevity. Discover how finding meaning in life can rewire your brain, boost your vitality, and unlock the secrets to living longer and healthier. Learn more about Dr Michael Mantz: https://x.com/michaelmantzmd Questions? Send us a message at: www.longevityjunky.com Follow us on soci...

Jan 20, 20251 hr 23 minSeason 12Ep. 20

119: NAD and Longevity Myths with Dr. Charles Brenner

Get ready to explore the cutting-edge science (and a little skepticism!) on all things longevity. In this episode, Nikki and Buck welcome Dr. Charles Brenner—a world-renowned expert on NAD biology and vocal critic of exaggerated longevity claims. Together, they unpack the hype versus the hard science behind aging, healthspan, and the latest buzz around supplements like NAD precursors. This unfiltered conversation blends fascinating research, practical takeaways, and a few hard truths about what ...

Jan 13, 20251 hr 11 minSeason 1Ep. 19

118: The Leaky Gut Epidemic with Dr. Steven Gundry

Is your gut the secret to a longer, healthier life? Join Buck and Nikki as they sit down with Dr. Steven Gundry, renowned cardiologist and best-selling author, to uncover the fascinating link between gut health, chronic inflammation, and longevity. From reversing autoimmune diseases to revealing why olive oil might just be your health MVP, this episode dives deep into groundbreaking insights and practical tips. Don’t miss this gut-wrenchingly good conversation! Learn more about Dr. Steven Gundry...

Jan 06, 202549 minSeason 1Ep. 18

117: Best of 2024 Holiday Special (Part 2)

We are back with part two of our holiday special, where Buck Joffrey and Nikki Leigh dive into transformative moments from 2024. From Nikki’s raw and revelatory ayahuasca experience to groundbreaking insights on ketamine as a life-changing therapy, this episode explores healing, hope, and the science of overcoming trauma. Plus, laugh-out-loud moments with Dr. Ashley Winter on sexual health and how stem cells might finally be able to fix Buck’s back pain. It’s a perfect blend of insight, humor, a...

Dec 30, 202449 minSeason 1Ep. 17

116: Best of 2024 Holiday Special (Part 1)

Celebrate the season with Longevity Junky ! In the first part of this special holiday episode, Buck Joffrey and Nikki Leigh revisit the most impactful conversations of 2024. From Aubrey de Grey’s cutting-edge insights on longevity escape velocity to Dr. Amen's brain health strategies—and more—join us for an inspiring journey through the highlights, heartfelt reflections, and a toast to your health and vitality in the new year! Questions? Send us a message at: www.longevityjunky.com Follow us on ...

Dec 23, 202456 minSeason 1Ep. 16

115: 83-Year-Old Ironman Neurosurgeon Reveals Secrets to Longevity and Brain Health

What if your 80s could feel like your 40s? Meet Dr. Joseph Maroon, an 83-year-old clinical neurosurgeon, world-class triathlete, and living proof that age is just a number. From pioneering concussion protocols for the NFL to crushing Ironman competitions, Dr. Maroon has mastered the art of thriving through resilience, science, and a relentless commitment to health. In this episode, Buck and Nikki dive into his remarkable story—how a midlife crisis transformed him into a champion of longevity, hi...

Dec 16, 20241 hr 10 minSeason 1Ep. 15
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