How little we know about what our ancestors really ate for dinner, with Richard Wrangham (0:00). How the field of neuroscience has changed over the past 25 years, with Eric Kandel (8:17). How countries are working to shape economic and social policies on biotechnology, even as the field is rapidly growing, with Jim Philp (15:15). Plus, sample a selection of the hottest new papers from Cell Press (21:43).
How epigenetics has changed the way that scientists think about heredity, with Nathan Springer (0:00). How researchers are using a trick of light to understand the behavior of single cells, with Christof Taxis (10:22). Plus, sample a selection of the hottest new papers from Cell Press (16:05).
How understanding of the cell nucleus has evolved over time, with Tom Misteli (0:00). How developments in biotechnology have spurred entire new industries over the last thirty years, with Bo Mattiasson(11:22). Plus, sample a selection of the hottest new papers from Cell Press (17:06).
How understanding neural control of appetite might help fight obesity, with Tamas Horvath (0:00) Trends in Neurosciences . How elemental design principles can provide insight into biological processing, with Wendell Lim (8:42) Molecular Cell . Plus, sample a selection of the hottest new papers from Cell Press (16:12).
In this month's Cell Podcast, we learn how llamas have helped the study of G protein-coupled receptors, with Brian Kobilka (0:00) ( Trends in Pharmacological Sciences ), how to teach an old genetic analysis test a cool new trick, with Trey Ideker (10:50) ( Cell Reports ). Plus, sample a selection of the hottest new papers from Cell Press (17:00).
In this month's Cell Podcast, we learn how designer techniques from synthetic biology are influencing the field of cell biology, with Wendell A. Lim and Wallace F. Marshall (0:00) ( Trends in Cell Biology ), how changes in specific genes triggered the evolution from fish fins to the limbs of vertebrates, with José Luis Gómez-Skarmeta and Fernando Casares (6:41) ( Developmental Cell ). Plus, sample a selection of the hottest new papers from Cell Press (13:42).
In this month's Cell Podcast, we learn about how stem cells from the testes may preserve fertility in young male cancer patients, with Kyle Orwig (0:00) ( Cell Stem Cell ), the crucial role of TGF-β in the spread of colorectal cancer, with Eduard Batlle (8:30) ( Cancer Cell ). Plus, sample a selection of the hottest new papers from Cell Press (15:15).
In this month's Cell Podcast, we learn about Developing drugs to tackle Schizophrenia, using rodents models, with Mark Geyer (0:00) (October issue of Trends in Pharmacological Sciences ), the role of next-gen sequencing in vaccine design, with Andrew Lloyd (8.50) (September issue of Trends in Biotechnology ), interpreting the genome to pinpoint mutations in an inherited blood disorder, with Vijay Sankaran (17.38), Plus, sample a selection of the hottest new papers from Cell Press (23.08)....
In this month's Cell Podcast, we learn about altering neuronal circuits depending on the environment, with Cori Bargmann (0:00) (Forthcoming Cell Symposia on Neuromodulatory Mechanisms), the role of mitochondria in diabetes, with Orian Shirihai (8:30) ( Trends in Endocrinology and Metabolism September Special issue), and how the power of the placebo has evolved over time, with Nicholas Humphrey (15:05) ( Current Biology September Special issue). Plus, sample a selection of the hottest new papers...
In this month's Cell Podcast, we cover the role of "friendly" gut bacteria in immune system defense, with Eric Pamer (0:00) ( Trends in Immunology Online Now), a potential treatment targeting a cannabinoid receptor that seems to reign in appetite and reduce body fat, with George Kunos (8:20) ( Cell Metabolism August issue), and the history and significance of mirror neurons, which fire when watching others' actions, with Marco Iacoboni (15:00) ( Current Biology 21st Anniversary Celebration). Plu...
In this month's Cell Podcast, we cover how a scorpion venom-derived peptide might be used to treat glioma, with Harald Sontheimer (0:00) ( Trends in Neurosciences June issue), visualizing the immune system in 3D to monitor inflammation in a whole organism, with Eric Skaar (7:58) ( Cell Host and Microbe June 14 issue), and understanding how mothers tolerate the "alien within" during pregnancy, with Alexander Rudensky (14:31) (Cell July 6 issue). Plus, sample a selection of the hottest new papers ...
In this month's Cell Podcast, we learn how neglected tropical diseases such as river blindness also have an underappreciated burden of mental health issues, with David Molyneux (0:00) ( Trends in Parasitology May Issue), a new approach to treating persistent neuropathic pain using embryonic cell transplants, with Allan Basbaum (7:26) ( Neuron May 24 Issue), and why we're celebrating two milestone birthdays in the stem cell field - 10 years of the ISSCR and 5 years of Cell Stem Cell , with Len Zo...
In this month's Cell Podcast, we learn how plant defenses have shaped the fussy dining habits of insects, with Anurag Agrawal (0:00) ( Trends in Plant Science Special Issue), why after twenty years, John O’Shea is still excited about cytokine signaling, (8:34) (Immunity Special Feature on the JAK-STAT pathway), and why being the right size is a matter of life or death for free-falling rodents, with Andrew Spence (15:15) ( Current Biology Special Issue on Size Control). Plus, sample a selection o...
In this month's Cell Podcast, we learn about how cells sense when they're feeling sluggish and need to refuel, with Claudio De Virgilio (0:00) (Bonfils et al. and Han et al.), a eureka moment in the lab becomes a new therapy in the clinic, with Laurie Glimcher (7:16) ( Cell Special Issue on Human Diseases), and a shape-shifting enzyme busts blood clots, with James Whisstock (14:12) (Law et al.). Plus, sample a selection of the hottest new papers from Cell Press (22:25).
In this month's Cell Podcast, we learn about the promises and potential perils of synthetic biology, with Vincent Martin and Tania Bubela (0:00), why sirtuin inhibitors may bring a cure for CML a step closer, with Ravi Bhatia (9:44), and how platelet producing cells avoid the pinch to become polyploid, with Diane Krause (14:56). Plus, sample a selection of the hottest new papers from Cell Press (23:14).
In this month's Cell Podcast, we learn how a lucky find in an obscure dental journal inspired the development of ibuprofen, with the drug’s discoverer Stewart Adams (0:00), why we’re still struggling to combat malaria, with Kip Guy (9:29), and how evolution finds multiple routes to the same phenotype, with Chris Marx (18:05). Plus, sample a selection of the hottest new papers from Cell Press (24:44).
In this month's Cell Podcast, we learn about why structural biologists need no longer fear the membrane, with Doug Rees (Tirado-Lee et al. and Special Reviews Collection) (0:00), why epithelial biology is going 3D (glasses not included), with Ian Macara (McCaffrey et al. and Special Issue of Trends in Cell Biology ) (8:42), and how sperm cells get their epigenetic message across, with Philippe Collas (Lindemann et al.) (13:54).
In this month's Cell Podcast, we learn about what mouse whiskers can tell us about how we perceive the world through touch, with David Kleinfield (0:00), how to stimulate heart repair by rewinding cardiomyocyte differentiation, with Thomas Braun (8:20), and a new strategy to stay one step ahead of the influenza virus, with Patrick Wilson (13:58).
In this month's Cell Podcast, we learn how to tune the intestinal immune system with microbial cocktails, with Dan Littman (0:00) (Sczesnak et al.), why there's more to DNA methylation than CpG islands in the hematopoietic system, with Greg Hannon (9:35) (Hodges et al.), where modern humans interbred with their ancient hominin cousins on the journey out of Africa, with Mark Stoneking (15:51) (Reich et al.), and whether humans are better team players than chimpanzees, with Daniel Haun (21:15) (Re...
In this month's Cell Podcast, we learn about the challenges of applying genetics to human mental health, with Trevor Robbins (0:00), a game of vesicular cat and mouse between bacterial lipids and the immune system, with Michael Brenner (10:48), and the shifting identities of stem-like cells in breast cancer, with Eric Lander (17:18).
In this month's Cell Podcast, we learn about how SUMOlyation wrestles hedgehog signaling into the right location during endocrine development, with Holly Ingraham (0:00), how neural stem cell progenitors are protected during starvation, from Alex Gould (12:01), and what's required in AML to make a cell susceptible to oncogenic transformation, explains Keith Humphries (17:48).
In this month's Cell Podcast, we learn about a lysosomal thread linking synucleinopathies, with Dimitri Krainc (0:00) (Mazzulli et al.), the genetics of human height, with Valerie Cormier-Daire (8:00), and polar bears: getting in touch with their surprising origins, with Beth Shapiro (14:31).
In this month's Cell Podcast, we learn about getting neural stem cells out of the lab and into the clinic, with Sally Temple (0:00), an important role for rare copy number variations in autism, with Matthew State and Michael Wigler (8:30), the dangers of midnight feasts for fruit fly fertility, with Amita Sehgal (18:04), and fitness costs and crosstalk in the evolution of host defense pathways, with Ruslan Medzhitov (24:32).
In this month's Cell Podcast, we learn about ape droppings and the origins of malaria, with Julian Rayner (0:00), A next-gen sequencing technique to study high-speed gene expression, with W. Lee Kraus (9:35), and Tracing the evolution of signaling pathways in plants, with Alistair Hetherington (15:56).
In this month's Cell Podcast, we learn about how HIV hides in hempatopoietic stem cells (0:00), combating tuberculosis drug resistance (7:25), and suppressing tumors with a protein isomerase (13:41).
Cellular "coin-flipping;" Jim Collins explains how cells make decisions (0:00), the vicious cycle of treating drug addiction as a criminal behavior, instead of a medical condition (8:23), and how small molecules can help uncover signaling crosstalk, when genetic strategies fail (16:56).
Engineering cyanobacteria to a make a profit—not just biofuels (0:00), why breast cancers often metastasize to the bone (11:03), and EPO's surprising anti-inflammatory properties (17:15).
Hunting down biomarkers for Alzheimer's diease (0:30), modeling Progeria with iPS cells (10:13), and how yeast spare their daughter cells from toxic aging factors (16:52).
Hear about filling in the gaps of the 1000 genomes project (0:50), learn about tracking down an elusive culprit of inherited diseases. (10:05), discover how chromatin-modifying enzymes orchestrate skin development (18:22).
Learn how skeletal stem cells are key to improving osteoporosis treatment regimes (1.00), discover what a new pain gene has in common with Hungarian composer Franz Liszt (10.33), and hear insights from new metabolomics analysis of the tuberculosis pathogen (17:51).
