In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, and William Morice II, M.D., Ph.D. , CEO and president of Mayo Clinic Laboratories, share insights from industry news and recent conferences, including PlatforMed . They explore: The significant interest in diagnostics for the advancement of cancer care. The Joint Commission’s collaboration with the Coalition for Health AI to establish guidelines for the responsible u...
Jul 03, 2025•14 min•Ep. 360
Joshua Bornhorst, Ph.D., explains how Mayo Clinic Laboratories' labile copper assay ( Mayo ID: LBCS ) improves upon standard blood tests for Wilson's disease. The new test measures not just overall copper but also the fraction of copper that is bioavailable, or labile bound. (00:32) Can you tell us a little bit about yourself and your background? (01:33) Could you give us a brief overview of this assay? (02:47) Which patients should have this testing, and when should it be performed? (03:48) How...
Jul 01, 2025•7 min•Ep. 359
John Lieske, M.D., and Sandra Taler, M.D., explain how Mayo Clinic Laboratories' mass spectrometry assay helps evaluate patients for resistant hypertension. The test detects antihypertensive medications in urine, providing evidence of whether patients are absorbing their medications or whether a new treatment approach might be needed. Speaker 3: (00:33) Could you tell us a little about yourselves and your backgrounds? Speaker 3: (01:41) Dr. Taler, could you provide us with a brief background on ...
Jun 24, 2025•12 min•Ep. 358
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, and Div Dubey, M.B.B.S. , a neurologist and co-director of the Clinical Neuroimmunology Laboratory at Mayo Clinic, explore the topic of peripheral neuropathy. Their discussion covers: The high prevalence of peripheral neuropathy and why early diagnosis is important. The complexities involved in diagnosing the condition. Symptoms that should prompt clinicians to order ...
Jun 19, 2025•16 min•Ep. 357
Joseph Yao, M.D., explains how Mayo Clinic Laboratories' new quantitative assay ( Mayo ID: ADVQU ) goes beyond qualitative testing to evaluate transplant patients for adenovirus infection. Adenovirus can cause life-threatening disease in immunocompromised transplant patients, especially children. (01:14) Could you give us a brief overview of this assay? (02:06) Can you explain the differences of the qualitative and quantitative methods and why we made the change to a quantitative adenovirus meth...
Jun 17, 2025•12 min•Ep. 356
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, and William Morice II, M.D., Ph.D. , CEO and president of Mayo Clinic Laboratories, discuss global trends in diagnostic manufacturing and their implications for laboratory professionals. Topics include: Emerging innovations in mass spectrometry, next-generation sequencing, automation, and artificial intelligence. Fierce competition in the global manufacturing landscap...
Jun 05, 2025•15 min•Ep. 355
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D. , CEO and president of Mayo Clinic Laboratories, to discuss the value laboratories deliver for their entire health system. They cover how laboratories impact: Growth in revenue Growth in lab charges Growth in ancillary services Hospital length of stay Control over expenses You can also find more in-depth information on this ...
May 22, 2025•22 min•Ep. 354
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D. , CEO and president of Mayo Clinic Laboratories, to discuss tick-borne diseases. They cover: Different diseases patients can get from ticks. Disease prevention, including Dr. Pritt’s A through Z flash cards with tips for people to protect themselves from infectious insects. Laboratory medicine’s valuable role in testing and ...
May 08, 2025•14 min•Ep. 353
In this episode of “Answers From the Lab,” William Morice II, M.D., Ph.D. , CEO and president of Mayo Clinic Laboratories, is joined by Russ Lebovitz, M.D., Ph.D., CEO and co-founder of Amprion . They discuss their strategic collaboration and the innovative SAAmplify™–αSYN (CSF) test. They covered: Details about how the cerebrospinal fluid biomarker test ( Mayo ID: ASYNC ) benefits patients exhibiting signs and symptoms of clinically uncertain cognitive decline or clinically uncertain Parkinsoni...
Apr 24, 2025•22 min•Ep. 352
Paul Jannetto, Ph.D., explains how Mayo Clinic Laboratories' SPAS test identifies the form of arsenic present in patients with arsenic exposure. That information is important for determining the potential level of harm and for removing the patient from the arsenic source to ease symptoms and prevent cancer risk. (00:33) Do you mind telling us a little bit about yourself and your background? (01:45) Could you please provide us with an overview of arsenic, how people get exposed, and the laborator...
Apr 15, 2025•11 min•Ep. 351
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D. , CEO and president of Mayo Clinic Laboratories, to discuss the recent court judgment on the U.S. Food and Drug Administration’s (FDA) oversight of lab-developed tests (LDT). They covered: Details about the ruling to vacate the FDA’s rule on LDT oversight. What LDT oversight might look like in the future. How the laboratory ...
Apr 10, 2025•12 min•Ep. 350
Jessica Wright, Pharm.D., BCACP, explains how Mayo Clinic Laboratories' 3A5Q test helps determine initial tacrolimus doses for individuals after non-liver organ transplants. Optimal tacrolimus levels are one of the important factors in survival of the transplanted organ. (00:32) Could you provide us a with little bit about your background and yourself? (03:45) Will you please provide a brief overview of Mayo test 3A5Q? (06:56) Which patients should have this testing, and when should it be perfor...
Apr 08, 2025•15 min•Ep. 349
In this episode of “Answers From the Lab,” William Morice II, M.D., Ph.D. , CEO and president of Mayo Clinic Laboratories, invited Min-Han Tan, M.B.B.S., FRCP, Ph.D., founding CEO and medical director of Lucence , to discuss liquid biopsy cancer testing . Mayo Clinic Laboratories and Lucence recently announced a collaboration to expand access to this cutting-edge cancer test that is designed to detect clinically relevant biomarkers in ctDNA and ctRNA. During their conversation, Dr. Morice and Dr...
Apr 03, 2025•11 min•Ep. 348
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D. , CEO and president of Mayo Clinic Laboratories, to discuss the evolution of retail health. They cover several key topics, including: The emergence of retail health locations. Three types of care that are well-suited for a retail approach to healthcare. The importance of incorporating diagnostics when designing retail health...
Mar 27, 2025•14 min•Ep. 347
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D. , CEO and president of Mayo Clinic Laboratories, to discuss infectious disease activity around the nation. They cover: The high prevalence of influenza A, avian influenza, measles, and COVID-19. Reliable resources for information on the spread of infectious diseases. Prevention measures and their impact on the spread of infe...
Mar 13, 2025•14 min•Ep. 346
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by Elitza Theel, Ph.D. , director of the Infectious Diseases Serology Laboratory at Mayo Clinic, for a conversation about innovation in testing for sexually transmitted infections (STI). Topics include: The advantages and challenges of new types of specimen collection and testing methods, including over-the-counter, at-home, and point-of-care options. Implic...
Feb 27, 2025•14 min•Ep. 345
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D. , CEO and president of Mayo Clinic Laboratories, for a conversation about quality management. Specifically, they discuss: The benefit of investing in quality management for patients, staff, and the organization. How Mayo Clinic’s Department of Laboratory Medicine and Pathology in Rochester evolved and grew its quality manage...
Feb 13, 2025•16 min•Ep. 344
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D. , CEO and president of Mayo Clinic Laboratories. They discuss recent business trends in diagnostics and why it is important for pathologists to stay informed about these trends. Their conversation covers: What’s driving a renewed interest in investing in diagnostics. Why the knowledge pathologists have is so valuable in the ...
Jan 30, 2025•18 min•Ep. 343
Sanjeev Sethi, M.D., Ph.D., explains how Mayo Clinic Laboratories' new mass spectrometry test (Mayo ID: MSMN) identifies most antigens now known to cause membranous nephropathy. Precise identification of antigens is important for optimal management of this serious kidney disease. (00:32) Would you mind telling us a little bit about yourself and your background? (01:58) Would you give us an overview of membranous nephropathy? (07:14) Could you tell us a little bit about this new assay? (14:29) Co...
Jan 21, 2025•20 min•Ep. 342
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D. , CEO and president of Mayo Clinic Laboratories. They discuss Dr. Morice’s recent article in Becker’s Hospital Review, “ Nine Developments Predicted to Shape Laboratory Medicine and Diagnostics in 2025 ,” and go deeper into conversation about: The rapid evolution of artificial intelligence and large language models. Digital ...
Jan 16, 2025•14 min•Ep. 341
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by Erin Graf, Ph.D., co-director of Microbiology in the Department of Laboratory Medicine and Pathology at Mayo Clinic in Arizona, to discuss benefits of automation in the laboratory. Topics of discussion include: Specific examples of how they are using automation in the laboratory. Strategies for ensuring a smooth implementation and a positive experience fo...
Jan 09, 2025•13 min•Ep. 340
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D. , CEO and president of Mayo Clinic Laboratories, to discuss emerging concerns about H5N1 avian influenza. Specific topics of discussion include: Patterns of transmission and what they indicate about the potential of person-to-person transmission. Tools, tests, and processes that emerged in recent years that are making it eas...
Jan 02, 2025•10 min•Ep. 339
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D. , CEO and president of Mayo Clinic Laboratories, to discuss the progress of artificial intelligence (AI) and what’s next in this space. Specific topics of discussion include: What’s driving the rapid acceleration of AI advancements. Ethical concerns and opportunities. How expenses, payment models, and culture influence AI ad...
Dec 12, 2024•16 min•Ep. 338
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D. , CEO and president of Mayo Clinic Laboratories, to discuss the latest in infectious disease outbreaks. Specific topics of discussion include: Recent trends in the spread of H5 bird flu and dengue fever. Why it’s important to think globally when monitoring infectious diseases. Extra precautions to take during the holiday tra...
Dec 05, 2024•11 min•Ep. 337
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D. , CEO and president of Mayo Clinic Laboratories, to discuss how labs can enhance patient access to improve health equity. Specific topics of discussion include: Innovations creating new possibilities, such as mobile clinics, at-home tests, and artificial intelligence. The responsibility of laboratory professionals to help gu...
Nov 21, 2024•15 min•Ep. 336
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by genetic counselors Carrie Lahner, M.S., CGC, and April Studinski Jones, M.S., CGC, to discuss how family medical history can inform genetic testing strategies. Specific topics of discussion include: The seven main types of genetic testing, and how clinicians know when and what genetic testing to order. Key family history details to collect to inform decis...
Nov 14, 2024•19 min•Ep. 335
John Logan Black, M.D., explains how Mayo Clinic Laboratories' UGT1A1 tests (Mayo IDs: U1A1Q and UGTFZ ) identify genetic variants that increase the risk of potentially life-threatening reactions to irinotecan, a chemotherapy agent. (00:32) Could you give us a brief overview about your background and yourself? (02:16) Could you explain the role of the UGT1A1 gene and its significance in the pharmacogenomics of irinotecan? (05:34) What specific tests do we offer for UGT1A1 at Mayo Clinic Laborato...
Nov 12, 2024•16 min•Ep. 334
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D. , CEO and president of Mayo Clinic Laboratories, to discuss recent outbreaks in vaccine-preventable diseases. Specific topics of discussion include: Recent increases in outbreaks of infectious diseases, such as pertussis, measles , and polio. The serious side effects of the diseases. What’s fueling the resurgence of these di...
Nov 07, 2024•11 min•Ep. 333
While confirmed cases for many respiratory illnesses are currently low, they will almost certainly spread as we move further into fall and winter. Now is the perfect time to prepare and take steps to protect yourself from everything from COVID-19 and influenza to RSV and the common cold. In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D. , CEO and president of Mayo Clinic La...
Oct 24, 2024•12 min•Ep. 332
Megan Hoenig, M.S., M.P.H., CGC, explains how Mayo Clinic Laboratories' unique hypermethylation analysis (Mayo ID: MLHPB ) provides critical adjunct information for managing Lynch syndrome. That genetic condition increases patients' risk for many kinds of cancer. Speaker 3: (00:32) Could you provide our listeners with a little bit about yourself and your background? Speaker 3: (01:27) Could you give an overview of our MLH1 hypermethylation, also referred to as MLHPB in our test catalog? Speaker ...
Oct 22, 2024•10 min•Ep. 331
