From cyberattacks to utility failures, technology disruptions are a growing risk in an increasingly digitized and automated laboratory environment. Planning for technology disruptions positions laboratories to embrace the full power of automation, artificial intelligence , and digitization while still meeting critical patient care needs during an outage. In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by ...
Oct 17, 2024•19 min•Ep. 330
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by Alicia Algeciras-Schimnich, Ph.D., a professor of laboratory medicine and pathology at Mayo Clinic and co-director of the Clinical Immunoassay Laboratory. They discuss Mayo Clinic’s plasma test for detecting Alzheimer’s disease and how it supports increased access and early detection. Specific topics of discussion include: The phospho-Tau 217 plasma test ...
Oct 10, 2024•9 min•Ep. 329
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by Dong Chen, M.D., Ph.D., chair of the Division of Hematopathology in the Department of Laboratory Medicine and Pathology at Mayo Clinic. They discuss rare and inherited platelet disorders and esoteric laboratory testing of hematologic disorders. Specific topics of discussion include: How these rare disorders are diagnosed through laboratory tests. Why plat...
Oct 03, 2024•23 min•Ep. 328
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories. They discuss the latest news in pathogen activity and how these viruses serve as an important reminder of the role of the public-private lab partnership. Their discussion includes: How the United States addresses emerging pathogens and the importance of a partnership between pu...
Sep 26, 2024•15 min•Ep. 327
Matthew Schultz, Ph.D., and Amy White, M.S., CGC, explain how Mayo Clinic Laboratories' unique urine assay (Mayo ID: SORD ) screens for peripheral neuropathy arising from SORD gene variants. Although recently identified, SORD -related peripheral neuropathy is fairly common. (00:31) Would you share a little bit about yourself and your background? (01:11) Could you provide us with an overview of this particular peripheral neuropathy? (03:09) Can you share the background as to how your team learned...
Sep 24, 2024•11 min•Ep. 326
In this episode of “Answers From the Lab,” William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories, is joined by special guest Donald Thomas, M.D., a rheumatologist and lupus researcher. They discuss how Mayo Clinic Laboratories’ suite of innovative lupus testing , offered in collaboration with Progentec Diagnostics , is enhancing the care and quality of life for patients affected by systemic lupus erythematosus (SLE). Their discussion includes: Symptoms of lupus and charac...
Sep 19, 2024•18 min•Ep. 325
John Mills, Ph.D., and Divyanshu Dubey, M.B.B.S., explain how Mayo Clinic Laboratories' new test panel can distinguish among various potential causes of demyelinating neuropathies. Test results are important for managing these devastating autoimmune conditions. Show notes Speaker 3: (00:32) Would you provide a little background on yourself, Dr. Mills? Speaker 3: (01:19) Dr. Dubey? Speaker 3: (02:07) Can you give a brief overview of our demyelinating test and recommended use? Speaker 3: (03:52) C...
Sep 17, 2024•14 min•Ep. 324
In this episode of “Answers From the Lab,” William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories, is joined by special guests Bernard Rubin, D.O., MPH, chief medical officer of Progentec Diagnostics, and Melissa Munroe, M.D., Ph.D., chief scientific officer and principal investigator of Progentec Diagnostics. They discuss Mayo Clinic Laboratories’ suite of innovative lupus testing , offered in collaboration with Progentec Diagnostics , for patients affected by systemic lu...
Sep 12, 2024•22 min•Ep. 323
Ann Moyer, M.D., Ph.D., explains how Mayo Clinic Laboratories' unique genetic tests identify patients at high risk of severe reactions to fluoropyrimidines — a type of chemotherapy drug. Test results can guide clinical decision-making for safer cancer treatment. Speaker 3: (00:32) Would you tell us a little bit about yourself and your history with this testing? Speaker 3: (01:25) Would you tell us a little more about this assay? Speaker 3: (04:57) Which patients should have this testing and when...
Sep 10, 2024•9 min•Ep. 322
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories, to discuss the latest advancements in Alzheimer’s disease testing and treatment. Their discussion includes: Why there is an increased focus on Alzheimer’s disease in the diagnostics industry. The development of groundbreaking blood tests that can detect Alzheimer’s-related biom...
Sep 05, 2024•14 min•Ep. 321
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories. They cover current trends, pain points, and opportunities for growth in the lab and diagnostics market. Their discussion includes: Insights from Dr. Morice’s participation in an Advisory Board webinar about 2024 lab market trends. Why there is an increased demand for laboratory...
Aug 29, 2024•14 min•Ep. 320
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by Matthew Binnicker, Ph.D., professor of laboratory medicine and pathology and clinical virologist at Mayo Clinic. They discuss the upsurge of mpox cases, particularly in Africa, and why the World Health Organization has declared it a public health emergency of international concern. Specific topics of discussion include: Background information on the monke...
Aug 22, 2024•16 min•Ep. 319
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories. They discuss what’s new and ongoing with pathogens and infections. Their discussion includes: Summer cases of COVID-19. H5N1 (avian influenza) activity and testing options. Increasing dengue fever infections. Outbreaks of listeria and cyclospora. The importance of public-privat...
Aug 15, 2024•8 min•Ep. 318
Maria Alice Willrich, Ph.D., and Melissa Snyder, Ph.D., explain how Mayo Clinic Laboratories' unique risankizumab panel measures levels of both that drug and its antibodies in patients' blood. The results can better guide the management of patients with inflammatory bowel disease. Speaker 4: (00:32) Please give the audience a little information about yourself and your background. Speaker 4: (02:12) Please give the audience a brief overview of this assay. Speaker 4: (04:34) Which patients should ...
Aug 06, 2024•10 min•Ep. 317
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories. They discuss insights from Dr. Morice’s recent travels abroad, including biomanufacturing, diagnostics, cybersecurity, and supply chain activities. Their discussion includes: What’s happening in the global diagnostics industry and takeaways from visiting Saudi Arabia and Italy....
Aug 01, 2024•10 min•Ep. 316
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by Elitza Theel, Ph.D., director of the Infectious Diseases Serology Laboratory at Mayo Clinic, to discuss the increase of dengue cases in the United States and around the world. Specific topics of discussion include: The characteristics and symptoms of dengue virus. Current dengue activity in the United States, why cases are increasing, and how it may impac...
Jul 25, 2024•16 min•Ep. 315
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories. They discuss how healthcare is a logical space to apply artificial intelligence (AI) technology and trends in how AI is being utilized. Their discussion includes: The benefits and pitfalls of using AI in clinical settings. Important factors to consider before implementing AI to...
Jul 18, 2024•14 min•Ep. 314
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories. They discuss a case that was recently overturned by the Supreme Court of the United States that may have ramifications for the healthcare industry, including impacts on regulatory oversight. Their discussion includes: A summary of the Supreme Court ruling on June 28 to overturn...
Jul 11, 2024•11 min•Ep. 313
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by Paul Jannetto, Ph.D., director of the Metals Laboratory at Mayo Clinic, and Sarah Erdahl, technical specialist coordinator in the Metals Laboratory. They discuss their unique opportunity to complete testing on locks of hair from the composer Ludwig von Beethoven. Specific topics of discussion include: How Mayo Clinic came to be involved in the project, an...
Jul 04, 2024•10 min•Ep. 312
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories. They discuss the summertime activity of COVID-19 and the latest updates with avian influenza (H5N1). Their discussion includes: The recent rise in COVID cases and how the new FLiRT variants of the virus are affecting the immune system. Updates on avian influenza activity and th...
Jun 27, 2024•9 min•Ep. 311
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories. They discuss the platform business model and how it’s being used in the healthcare industry to drive innovation and reimagine how care is provided. Their discussion includes: Key takeaways from the recent conference hosted by Mayo Clinic Platform. What constitutes a platform an...
Jun 13, 2024•14 min•Ep. 310
Anastasia Zekeridou, M.D., Ph.D., explains how Mayo Clinic Laboratories' updated panels and methodology boost the accuracy and efficiency of testing for three autoimmune neurology biomarkers. Early diagnosis is key to managing debilitating conditions associated with these antibodies. (00:32) Could you please give our listeners an overview of your role at Mayo Clinic? (01:22) What updates are happening in our laboratory to increase specificity when we receive a patient's serum and CSF for most of...
Jun 11, 2024•17 min•Ep. 309
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by William Morice II, M.D., Ph.D., CEO and president of Mayo Clinic Laboratories. They discuss why measles remains a virus of concern, how avian flu continues to spread, and new developments in the federal regulation of laboratory-developed tests. Their discussion includes: How a person infected with measles recently traveled through a U.S. airport, and the ...
Jun 06, 2024•15 min•Ep. 308
Divyanshu Dubey, M.B.B.S., explains how Mayo Clinic Laboratories' unique PDE10A and TRIM46 assays facilitate care for central nervous system disorders triggered by cancer. Early diagnosis and treatment are important for managing disabling neurological symptoms and malignancy. (00:32) Could you tell us a bit about your background and your role at Mayo Clinic? (01:26) How do the tests that are coming live relate to the larger disease state of neurological disorders? (02:44) Can you share a little ...
Jun 04, 2024•14 min•Ep. 307
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by Peter Lucas, M.D., Ph.D., vice chair of Research for the Department of Laboratory Medicine and Pathology (DLMP) at Mayo Clinic. Their discussion includes: Dr. Lucas’ extensive pathology and research background and his journey to Mayo Clinic. His goals for expanding DLMP’s research activities and advancing innovation in diagnostics. How laboratory research...
May 30, 2024•25 min•Ep. 306
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by Matthew Binnicker, Ph.D., professor of laboratory medicine and pathology and clinical virologist at Mayo Clinic. They discuss the widespread outbreaks of H5N1 bird flu and the new “FLiRT” variants of COVID-19. Specific topics of discussion include: The current situation of avian flu activity across the world and throughout the United States, including out...
May 23, 2024•11 min•Ep. 305
Robert Jenkins, M.D., Ph.D., Stephanie Smoley, CG(ASCP), and Beth Pitel, M.S., explain how Mayo Clinic Laboratories' augmented MayoComplete Solid Tumor Panel better profiles tumor genetics. Defining tumor pathogenesis can guide targeted cancer therapy. (00:31) Can you tell us a little about yourself and your background — Beth? (01:24) Stephanie, what about you? (01:42) Dr. Jenkins, a little bit about yourself and your background, please? (02:25) Could you provide a brief overview of the new Mayo...
May 21, 2024•14 min•Ep. 304
Rapidly progressive dementia covers many conditions, including Creutzfeldt-Jacob disease (CJD). Gregory (Gregg) Day, M.D., explains how Mayo Clinic Laboratories' new evaluations help identify the cause of rapidly progressive dementia, to guide prognosis and treatment decisions. Show notes Speaker 3: (00:32) Can you provide a little background about your role here at Mayo Clinic and experience with this disease state? Speaker 3: (01:21) Can you give us an understanding of rapidly progressive deme...
May 14, 2024•24 min•Ep. 302
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by Eric Hsi, M.D., chair of the Department of Laboratory Medicine and Pathology at Mayo Clinic. Their discussion includes: Dr. Hsi’s experience in the field of pathology and what he is looking forward to working on as the new chair of the Department of Laboratory Medicine and Pathology (DLMP) at Mayo Clinic. Some common challenges facing laboratory professio...
May 09, 2024•12 min•Ep. 301
Paul Jannetto, Ph.D., explains the advantages that Mayo Clinic Laboratories' oral fluid drug screening offers over typical urine tests. Oral samples are easier to collect and harder to adulterate. (00:32) Can you tell us a little bit about yourself and your background? (01:46) Can you please provide an overview of laboratory testing for substance use disorders and specifically Mayo Clinic's new oral fluid controlled substance monitoring option? (03:47) Which patients should have this testing and...
May 07, 2024•8 min•Ep. 300
