Timestamps: (0:00) Roy Lee's hack and Amazon's reaction (3:03) MicroStrategy's Bitcoin strategy(4:29) Market reactions to Trump's policies(6:33) Creating value in current market conditions(8:00) South by Southwest highlights (10:19) Coda. Empower your startup with Coda’s Team plan for free—get 6 months at https://www.Coda.io/twist (12:03) The $20,000 electric car concept(16:18) Electric unicycles as a startup category (19:12) Vanta. TWiST listeners automate your SOC2 and get $1,0...
Mar 11, 2025•1 hr 1 min•Transcript available on Metacast Today’s show: AI is evolving at lightning speed—smarter assistants, faster models, and now, the massive energy demands that come with it. In this episode, Alex dives into two cutting-edge companies from the TWIST 500 that are shaping AI’s future in very different ways. First, Alex interviews Zap Energy, where CEO Benj Conway explains how their breakthrough fusion power technology could provide unlimited, clean energy to fuel AI and beyond. Then, we talk to PolyAI, where CEO Nikola Mrkšić shares ...
Mar 07, 2025•49 min•Transcript available on Metacast This Week in Startups is brought to you by… Northwest Registered Agent. Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today! Lemon.io . Get 15% off your first 4 weeks of developer time at https://Lemon.io/twist Horatio. Visit https://www.hirehoratio.com/twist and get $2,000 off your initial set up. Today’s show: Jason and Alex cover CoreWeave’s filing for a $35 billion IPO af...
Mar 05, 2025•1 hr 9 min•Ep 2093•Transcript available on Metacast In this episode: Jason sits down with Harrison Chase, CEO of LangChain, to explore how AI-powered agents are transforming the way startups operate. They discuss the shift from traditional entry-level roles to AI-driven automation, the importance of human-in-the-loop systems, and the future of AI-powered assistants in business. Harrison shares insights on how companies like Replit, Klarna, and GitLab are leveraging AI agents to streamline operations, plus a look ahead at what's next for AI-dr...
Mar 04, 2025•20 min•Transcript available on Metacast Today’s show: Trump just floated the idea of a U.S. Crypto Reserve, suggesting a 10 bips transaction tax and naming unexpected altcoins like XRP, Solana, and Cardano. Jason and Alex break down what this means for crypto markets, regulation, and startups—plus the legal and political fallout. Is this a game-changer or just another pump-and-dump controversy? * Timestamps: (0:00) Alex and Jason kick of the show!(1:48) Trump's crypto policy and PR strategy(7:14) Analysis of Trump's proposed U...
Mar 04, 2025•59 min•Transcript available on Metacast Today’s show: Jason and Alex break down the latest head-scratching SEC ruling on meme coins—did they just legalize pump-and-dumps to protect Trump’s token? Plus, they dive into why venture debt can destroy startups, the rise of AI-driven companies, and how Tesla is gearing up to challenge Waymo in the self-driving car race. Then, Brandon Brown from GRIN joins the show to talk about scaling to 8-figure revenue, surviving brutal market corrections, and why he’s stepping down as CEO after a decade....
Mar 01, 2025•1 hr 15 min•Transcript available on Metacast Today’s show: Jason interviews Rahul Vohra, CEO and founder of Superhuman, and Vlad Tenev, CEO and co-founder of Robinhood. This is a packed episode featuring founder tips, fun stories about how Superhuman and Robinhood got their start and much more! Timestamps: (0:00) Episode teaser(2:13) Product market fit and founder journeys(3:25) Jason's investment in Superhuman and market positioning(5:14) AI's role and features in Superhuman(10:25) Lemon.io . Get 15% off your first 4 weeks of deve...
Feb 27, 2025•2 hr 39 min•Ep 2090•Transcript available on Metacast Today’s show: Jason and Lon break down the latest trends shaping AI training, the evolving job market, and the shifting landscape of social media. A tribute to Steve Jobs on what would have been his 70th birthday explores his lasting impact, Apple’s massive $500 billion AI investment, and the future of US manufacturing. The conversation dives into Outlier’s role in AI training data, its effects on journalism, and broader job market implications. Jason also shares insights on autonomous vehicles,...
Feb 25, 2025•1 hr 8 min•Transcript available on Metacast This Week in Startups is brought to you by… Squarespace. Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWIST LinkedIn Jobs. Post your first job for free at https://www.linkedin.com/twist AdQuick. Visit https://adquick.com/twist and mention TWIST to get $1000 off your first campaign. Today’s show: Jason interviews Bryon Hargis, CEO of Castelion, about the United State’s hypersonic technology gap with China, how we’re catching up and...
Feb 22, 2025•56 min•Ep 2088•Transcript available on Metacast This Week in Startups is brought to you by… Gusto. Get three months free when you run your first payroll at http://gusto.com/twist *Gusto pricing shown in ad is based on pricing prior to March 2025 Lemon.io . Get 15% off your first 4 weeks of developer time at https://Lemon.io/twist Atlassian. Head to https://www.atlassian.com/software/startups to see if you qualify for 50 free seats for 12 months. Today’s show: Jason and Lon Harris cover Nikola’s Chapter 11 and how founders can avoid the same m...
Feb 20, 2025•1 hr 7 min•Ep 2087•Transcript available on Metacast In today's episode: Jason and Alex break down one of the craziest crypto stories yet—a $100M meme coin meltdown, insider trading, and Argentina’s president caught in the middle. Coffeezilla joins the show to explain how meme coins are rigged, why Dave Portnoy got a $5M refund while everyone else got wrecked, and what really went down with the Libra token. Plus, we debate if crypto can be fixed or if the grift is too far gone. Timestamps: (0:00) Jason and Alex kick off the show.(2:17) Libra f...
Feb 19, 2025•1 hr 10 min•Transcript available on Metacast Today’s show: IPO shakeups, big AI moves, and essential founder hacks—this episode covers it all. Jason breaks down Robinhood’s 6X stock surge and his strategy for $HOOD, plus the latest on tech IPOs as Turo pulls out and SailPoint surges. We dive into AI’s open-source battle, with X.ai chasing a $10B raise and DeepSeek challenging Hugging Face. And for founders, Jason shares the startup golden rule you should break for success—plus, a brand-new startup idea he’s willing to fund right now. * Tim...
Feb 15, 2025•1 hr 20 min•Transcript available on Metacast This Week in Startups is brought to you by… Vanta. Get $1000 off your SOC 2 at https://www.vanta.com/twist Northwest Registered Agent. Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit northwestregisteredagent.com/twist today! LinkedIn Ads. Get a $100 LinkedIn ad credit at http://www.linkedin.com/thisweekinstartups Today’s show: Jason and Alex cover…TBD Timestamps: (0:00) Episode Teaser(1:16) Welcome Alex Wilhelm & Sam Le...
Feb 12, 2025•1 hr 5 min•Ep 2084•Transcript available on Metacast Today on This Week in Startups: Lon Harris is back, and we’re diving into all things Super Bowl—especially the tech takeover in this year’s commercials. We break down the biggest ad moments, from Squarespace to Uber Eats, Instacart, and even Harrison Ford’s Jeep spot. Plus, we dig into Google Trends after the ChatGPT ad, the unexpected appeal of The Banshees of Inisherin , and Matthew McConaughey’s latest move with Salesforce. That’s not all—France is making bold AI moves, OpenAI is getting into...
Feb 11, 2025•1 hr 5 min•Transcript available on Metacast This Week in Startups is brought to you by… Squarespace. Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWIST Atlassian. Head to https://www.atlassian.com/software/startups to see if you qualify for 50 free seats for 12 months. AdQuick. Visit https://adquick.com/twist and mention TWIST to get $1000 off your first campaign. Today’s show: Jason and Alex discuss the carried interest tax loophole being in Trump’s crosshairs, a great int...
Feb 08, 2025•1 hr 3 min•Ep 2082•Transcript available on Metacast This Week in Startups is brought to you by… Gusto. Get three months free when you run your first payroll at http://gusto.com/twist *Gusto pricing shown in ad is based on pricing prior to March 2025 Oracle. TWiST listeners can try OCI and save up to 50% on your cloud bill at https://www.oracle.com/twist Horatio. Visit https://www.hirehoratio.com/twist and get $2,000 off your initial set up. Today’s show: Jason and Alex cover Palantir’s surge (is it all hype?), Temo and Shein and the de ...
Feb 06, 2025•58 min•Ep 2081•Transcript available on Metacast OpenAI dropped Deep Research —hilariously, the exact same name as Google’s existing tool. Jason and Alex dive into the AI arms race, break down Lovable.dev’s insane growth to $10M ARR in weeks, and test whether AI can really replace software engineers. Plus, they analyze Trump’s latest tariff chaos and what it means for startups, global trade, and the economy. * Timestamps: (0:00) Jason and Alex kick off the show. (1:09) Jason’s talk and case study at Stanford (2:38) Managing the chaotic news cy...
Feb 04, 2025•1 hr 7 min•Transcript available on Metacast Today’s show: The AI revolution is about to hit your household—Jason and Alex break down how general-purpose robots, AI-powered chicken coops, and voice clones are redefining daily life and work. They dig into OpenAI’s sky-high valuation, the surprising rise of DeepSeek’s R1 model, and why the AI cost curve is dropping at an insane pace. Plus, the latest on AI hardware, antitrust battles, and why the “No Buy 2025” trend could change how we think about consumer tech. * Timestamps: (0:00) Jason an...
Feb 01, 2025•1 hr 13 min•Transcript available on Metacast This Week in Startups is brought to you by… Vanta. Get $1000 off your SOC 2 at https://www.vanta.com/twist Northwest Registered Agent. For just $39 plus state fees, Northwest will handle your complete business identity. Visit https://northwestregisteredagent.com/twist today. Scalable Path. Get 20% off your first month at https://www.scalablepath.com/twist Today’s show: Jason and Alex cover Jason’s unique sauna experience, leading them to discuss the value of niche communities and supporting sm...
Jan 29, 2025•1 hr 3 min•Transcript available on Metacast Today’s show: A $6M open-source AI model from China, DeepSeek, sends shockwaves through Wall Street, wiping billions off NVIDIA’s market cap and forcing a rethink on AI infrastructure spending. We explore the 25% surge in startup shutdowns, the lessons from leaner teams, and why some companies just couldn’t make the runway. Plus, SailPoint returns to the public markets saddled with $1.6B in debt—what does this say about private equity’s “buy, fix, and flip” strategy? Don’t miss this deep dive in...
Jan 27, 2025•1 hr•Transcript available on Metacast This Week in Startups is brought to you by… Fitbod. Get 25% off your Fitbod subscription or try out the app for FREE when you sign up: fitbod.me/TWIST Squarespace. TWiST listeners: use code TWIST to save 10% off your first purchase of a website or domain: https://www.Squarespace.com/TWIST Horatio. Visit https://www.hirehoratio.com/twist and get $2,000 off your initial set up. Today’s show: Jason and Alex cover Twilio’s team size compression, DeepSeek’s scary good AI for only $6M and the GameOn f...
Jan 24, 2025•58 min•Transcript available on Metacast This Week in Startups is brought to you by… Gusto. Get three months free when you run your first payroll at http://gusto.com/twist *Gusto pricing shown in ad is based on pricing prior to March 2025 Netsuite. Download the CFO's Guide to AI and Machine Learning for free at https://www.netsuite.com/twist Atlassian. Head to Atlassian.com/Startups/TWiST to see if you qualify for 50 free seats for 12 months. Today’s show: Alex covers The Stargate Project, other hot news items, and two great interv...
Jan 23, 2025•59 min•Transcript available on Metacast Today’s show: Jason and Alex explore America's fascination with billionaires and self-made figures, touching on recent events in Washington, DC, and the tech industry's political influence. They discuss Gen X's rising political power, tech CEOs' prominence at inaugurations, and critique Democrats' tech policies. The conversation covers economic factors in elections, like inflation and abortion rights, COVID's origins, immigration policy, and foreign policy. AI regulation ...
Jan 21, 2025•1 hr 12 min•Transcript available on Metacast Today’s show: Alex sits down with two CEOs from companies freshly added to the TWIST500. We get a masterclass from Bob van Luijt of Weaviate, on vector databases helping AI and LLMs do what they do. An then Philip Johnston from Lumen Orbit explains his vision of building data centers in space! * Timestamps: (0:00) Alex kicks off the show. (0:58) Supreme Court ruling on TikTok and key market numbers (3:49) Interview introduction with Weaviate and Lumen Orbit CEOs (4:06) Deep dive into vector data...
Jan 17, 2025•1 hr 3 min•Transcript available on Metacast This Week in Startups is brought to you by… PrizePicks. TWiST listeners, download the app today and use code TWIST to get $50 instantly after you play your first $5 lineup! Go to: https://prizepicks.onelink.me/LME0/TWIST PrizePicks - Run your game. Coda. TWiST listeners get 6 months at https://www.Coda.io/twist Fitbod. Get 25% off your Fitbod subscription or try out the app for FREE when you sign up: fitbod.me/TWIST Today’s show: Jason and Alex interview Aarush Selvan, lead PM at Google Gemini D...
Jan 16, 2025•1 hr 8 min•Ep 2072•Transcript available on Metacast Today’s show: Alex covers Mark Zuckerberg’s Joe Rogan interview, OpenAI’s economic pitch and the pending IPO of India’s Groww. Our guests include two companies freshly added to the TWIST500: James Cadwallader from Profound and Martin Rehak from Resistant AI. * Timestamps: (0:00) Alex kicks off the show! (2:51) A look at key moments from this week’s Mark Zuckerberg interview on Rogan. (8:08) James Cadwallader, Co-Founder and CEO of Profound join Alex. (10:05) Northwest Registered Agent. For just ...
Jan 14, 2025•1 hr 7 min•Transcript available on Metacast This Week in Startups is brought to you by… Northwest Registered Agent. For just $39 plus state fees, Northwest will handle your complete business identity. Visit https://www.northwestregisteredagent.com/twist t today. Atlassian. Head to https://www.atlassian.com/Startups/TWiST to see if you qualify for 50 free seats for 12 months. LinkedIn Ads. To redeem a $100 LinkedIn ad credit and launch your first campaign, go to http://www.linkedin.com/thisweekinstartups Today’s show: Jason and Alex cove...
Jan 10, 2025•56 min•Transcript available on Metacast This Week in Startups is brought to you by… Gusto. Get three months free when you run your first payroll at http://gusto.com/twist *Gusto pricing shown in ad is based on pricing prior to March 2025 Oracle. TWiST listeners can try OCI and save up to 50% on your cloud bill at https://www.oracle.com/twist Squarespace. TWiST listeners: use code TWIST to save 10% off your first purchase of a website or domain: https://www.Squarespace.com/TWIST Today’s show: Jason and Alex discuss Meta’s modera...
Jan 08, 2025•1 hr 8 min•Ep 2069•Transcript available on Metacast This Week in Startups is brought to you by… PrizePicks. TWiST listeners, download the app today and use code TWIST to get $50 instantly after you play your first $5 lineup! Go to: https://prizepicks.onelink.me/LME0/TWIST PrizePicks - Run your game. Lemon.io . TWiST listeners get 15% off your first 4 weeks of developer time at https://Lemon.io/twist Vanta. TWiST listeners automate your SOC2 and get $1,000 off at http://www.vanta.com/twist Today’s show: Jason and Alex cover Sam Altman’s fusion pro...
Jan 06, 2025•1 hr 9 min•Transcript available on Metacast This Week in Startups is brought to you by… Paddle. Wherever you want to take your business, go there with Paddle. Go to paddle.com/twist to get started with your exclusive listener fee-free period. Fitbod. Get 25% off your Fitbod subscription or try out the app for FREE when you sign up now at fitbod. me/TWIST . LinkedIn Ads. Get a $100 LinkedIn ad credit: http://www.linkedin.com/thisweekinstartups Todays show: Jason and Alex discuss the over saturation of venture capital, how to fix the high-s...
Jan 04, 2025•1 hr 8 min•Transcript available on Metacast 
