In the summer of 2003, Europe experienced its most intense heatwave on record - one that saw more than 70,000 people lose their lives. Experiencing the effects whilst on holiday in Tuscany, climate scientist Peter Stott was struck by the idea that just maybe, he could use a modelling system developed by his team at the UK’s Meteorological Office, to study extreme weather events such as this very heatwave mathematically; and figure out the extent to which human influences were increasing their pr...
Mar 11, 2025•26 min•Transcript available on Metacast Imagine a nanoparticle, less that a thousandth of the width of a human hair, that is so precise that it can carry a medicine to just where it’s needed in the body, improving the drug’s impact and reducing side effects. Ijeoma Uchegbu, Professor of Pharmaceutical Nanoscience at University College London, has spent her career with this goal in mind. She creates nanoparticles to carry medicines to regions of the body that are notoriously hard to reach, such as the back of the eye and the brain. Wit...
Mar 03, 2025•26 min•Transcript available on Metacast Darren Croft studies one of the ocean’s most charismatic and spectacular animals – the killer whale. Orca are probably best known for their predatory behaviour: ganging up to catch hapless seals or attack other whales. But for the last fifteen years, Darren Croft’s focus has been on a gentler aspect of killer whale existence: their family and reproductive lives . Killer whales live in multi-generational family groups. Each family is led by an old matriarch, often well into her 80s. The rest of t...
Feb 25, 2025•26 min•Transcript available on Metacast Bill Gates is one of the world's best-known billionaires - but after years at the corporate coalface building a software empire and a vast fortune, his priority now is giving that wealth away. And his ethos for doing it has been shaped by science. Famed for co-founding Microsoft, in recent decades Bill’s attention has turned to philanthropy via The Gates Foundation: one of the largest charities in the world. Since its inception in 2000, the organisation has helped tackle issues around health, ed...
Feb 17, 2025•26 min•Transcript available on Metacast A small, informal survey leads to shocking revelations about the US justice system, with its truths only uncovered decades later. Meanwhile, an ambitious portfolio manager discovers a perfect graph outlining eye-watering profits. But something does not seem right. Could the graph be accurate, or is it hiding a far more sinister truth? This story delves into the power of data, the hidden forces behind it, and the unexpected revelations that can change everything
Feb 10, 2025•26 min•Transcript available on Metacast At a conference in Mexico, one scientist’s outburst sparks a global quest to find a ‘golden spike’ - the boundary marking the shift into a new geological period dominated by humans, not volcanoes or asteroids. From plastics and concrete to nuclear fallout, the data they uncover reveals a planet profoundly altered. But can they convince their colleagues and the world of the extent of this transformation? Meanwhile, in a small Italian city nestled in the Apennine mountains, a series of low-level t...
Feb 03, 2025•26 min•Transcript available on Metacast A PhD student with a passion for whales stumbles upon a strange, eerie sound deep beneath the ocean waves, something that will soon rock her world. Meanwhile, a fisherman is stranded in the ocean late at night, completely alone. With time running out, can he be rescued before it is too late? From mysterious discoveries to life-or-death struggles, this story delves into the power of the ocean and the determination to survive.
Jan 27, 2025•26 min•Transcript available on Metacast Amid the desperation of war-starved Netherlands, a doctor defies conventional wisdom to save gravely ill children, uncovering a treatment that sparks both hope and controversy. Years later, in 1967, a young female researcher detects a strange, pulsing signal. Could it be mundane interference or evidence of alien life? From lifesaving breakthroughs to cosmic discoveries, this story celebrates the determination of pioneers who challenge convention and pursue truth against the odds.
Jan 20, 2025•26 min•Transcript available on Metacast A mathematician searching for love discovers that relationships aren’t always as simple as equations—are his calculations the issue, or is there something deeper at play? Meanwhile, at an engineering conference, a young researcher’s seemingly minor mistake uncovers a scandal of epic proportions. Can numbers find love or unveil problems? From personal dilemmas to professional revelations, this episode dives into the unexpected ways numbers can change lives.
Jan 13, 2025•26 min•Transcript available on Metacast In 2016, Niall McCann was left with a bruised spinal cord when he crashed his speed glider into the side of a mountain at 50mph. He shares his journey to recovery and some unexpected life lessons he has had to navigate, from soiling himself in inconvenient places and not being able to control his flatulence, to having to re-learn how to have sex again. We also hear from a Mountain Rescue medic on what looked like an “unsurvivable” situation and Niall’s surgeon on fixing his “exploded” spine....
Jan 06, 2025•26 min•Transcript available on Metacast Perhaps you couldn't drift off, or maybe you woke in the middle of the night and then couldn't nod off again. In this edition of Inside Health we're talking all about insomnia. It’s an issue that may affect many of us at some point in our lives – but for some it goes beyond a short period of not being able to sleep and becomes something more serious. James is joined by a trio of experts ready to answer to them: Dr Allie Hare, president of the British Sleep Society and consultant physician in sle...
Dec 31, 2024•28 min•Transcript available on Metacast Dr Chris van Tulleken shares stories from the making of his chart-topping podcast, Fed. In conversation with Leyla Kazim, at Hay Festival 2024. In Fed, Dr Chris van Tulleken, investigated the entangled web of forces that shape what ends up on our plates. And he focused his investigation around one foodstuff in particular. The most widely eaten meat on our planet, a staple of nearly every diet and a global food production phenomenon: the humble chicken, Chris dug into the history of our relations...
Dec 23, 2024•28 min•Transcript available on Metacast From the Hay Festival, James and a panel of experts explain what we can all do to help ourselves age well. We discover what’s going on in our bodies when we age, the difference between biological and chronological age, as well as getting the audience moving for a physical test. James is joined by gerontologist Sarah Harper from the University of Oxford, biomedical scientist Georgina Ellison-Hughes from King’s College London, and doctor Norman Lazarus to understand how exercise, diet, and mental ...
Dec 16, 2024•26 min•Transcript available on Metacast Throbbing head, nausea, dizziness, disturbed vision – just some of the disabling symptoms that can strike during a migraine attack. This neurological condition is far more common than you might think, affecting more people than diabetes, epilepsy and asthma combined. While medications, to help relieve the symptoms of migraine, have been around for some time, they haven’t worked for everyone. And what happens in the brain during a migraine attack was, until recently, poorly understood. Peter Goad...
Dec 09, 2024•26 min•Transcript available on Metacast Kip Thorne is an emeritus professor of theoretical physics at Caltech, the California Institute of Technology, and someone who has had a huge impact on our understanding of Einsteinian gravity. Over the course of his career Kip has broken new ground in the study of black holes, and been an integral parts of the team that recorded gravitational waves for the very first time – earning him a share in the 2017 Nobel Prize for Physics. He went on to promote physics in films: developing the original i...
Dec 02, 2024•26 min•Transcript available on Metacast It's summer - no really - and although the weather might have been mixed, the sporting line-up has been undeniably scorching - from the back-and-forth of Wimbledon, to the nail-biting Euros, to the current pageantry of the Summer Olympics. Next month the 2024 Paralympic Games get underway in Paris, involving the world’s very best para athletes; and Professor Vicky Tolfrey is at the forefront of the science that makes their sporting dreams a reality. Vicky is the Director of the Peter Harrison Ce...
Nov 25, 2024•26 min•Transcript available on Metacast The engineering industry, like many other STEM sectors, has a problem with diversity: one that Dawn Bonfield believes we can and must fix, if we're to get a handle on much more pressing planetary problems... Dawn is a materials engineer by background, who held roles at Citroën in France and British Aerospace in the UK. But, after having her third child, she made the difficult decision to leave the industry - as she thought at the time, for good. However a short spell working in post-natal servic...
Nov 18, 2024•26 min•Transcript available on Metacast In recent decades, we have taken huge steps forward in treating formerly fatal viruses - with pharmacological breakthroughs revolutionising treatment for conditions such as HIV, hepatitis and herpes. Raymond Schinazi has played a big role in that revolution. Ray was born in Egypt, where his mother’s brush with a potentially deadly illness during his childhood inspired a fascination with medicine. His childhood was scattered; after his family were forced to leave their homeland and travelled to I...
Nov 11, 2024•26 min•Transcript available on Metacast From anorexia nervosa to binge-eating, eating disorders are potentially fatal conditions that are traditionally very difficult to diagnose and treat - not least because those affected often don’t recognise that there’s anything wrong. But also because of the diverse factors that can influence and encourage them. Janet Treasure is a Professor of Psychiatry at King’s College, London - where she's focused on understanding the drivers behind these disorders, to help develop more effective treatments...
Nov 04, 2024•26 min•Transcript available on Metacast Marfan syndrome is a genetic disorder that makes renders the body’s connective tissues incredibly fragile; this can weaken the heart, leading to potentially fatal aneurysms. What’s more, anyone with the condition has a 50/50 chance of passing it on to their children. Dr Anne Child is a clinical geneticist who’s dedicated her professional life to finding answers and solutions for people affected by Marfan’s. Born in Canada, she met her British future-husband while working in Montreal in a case sh...
Oct 28, 2024•26 min•Transcript available on Metacast Many of us have heard of seismology, the study of earthquakes; but what about asteroseismology, focusing on vibrations in stars? Conny Aerts is a professor of Astrophysics at the University of Leuven in Belgium - and a champion of this information-rich field of celestial research. Her work has broken new ground in helping to improve our understanding of stars and their structures. Conny describes herself as always being “something of an outlier” and she had to fight to follow her dream of workin...
Oct 21, 2024•26 min•Transcript available on Metacast When does a crowd of people become unsafe? How well will the football team Aston Villa do next season? When is it cost-effective to replace a kitchen? The answers may seem arbitrary but, to Nira Chamberlain, they lie in mathematics. You can use maths to model virtually anything.
Oct 14, 2024•26 min•Transcript available on Metacast A top secret little-known mission that changed the outcome of World War II. Not Alan Turing's Enigma code-breaking mission but a daring foray, conducted behind enemy lines on the shores of Normandy. Harrison Lewis and wetland scientist Christian Dunn re-enact one of the most remarkable feats of the Second World War and discover the intricate details of the daring but forgotten science that underpinned D-Day.
Oct 07, 2024•26 min•Transcript available on Metacast Take a trip around the supermarket and you'll see shelves of products claiming to be 'high in protein'. Scroll through your social media and you'll find beautiful, sculpted people offering recipes and ideas for packing more protein into your diet. Science presenters Dr Julia Ravey and Dr Ella Hubber have noticed this too. They wanted to unpick the protein puzzle to find out what it does in our bodies and how much we really need. Can this macronutrient really help us lose weight, get fit and be h...
Sep 30, 2024•26 min•Transcript available on Metacast What is the universe made of? Where does space dust come from? And how exactly might one go about putting on a one-man-show about Sir Isaac Newton? These are all questions that Mike Edmunds, emeritus professor of astrophysics at Cardiff University and president of the Royal Astronomical Society (RAS), has tackled during his distinguished career. And although physics is his first love, Mike is fascinated by an array of scientific disciplines - with achievements ranging from interpreting the sprea...
Sep 23, 2024•26 min•Transcript available on Metacast With 86 billion nerve cells joined together in a network of 100 trillion connections, the human brain is the most complex system in the known universe. Dr Hannah Critchlow is an internationally acclaimed neuroscientist who has spent her career demystifying and explaining the brain to audiences around the world. Through her writing, broadcasting and lectures to audiences – whether in schools, festivals or online – she has become one of the public faces of neuroscience. She tells Prof Jim Al-Khali...
Sep 16, 2024•26 min•Transcript available on Metacast The reputation of the nuclear industry has had highs and lows during the career of Dr Fiona Rayment, the President of the Nuclear Institute. But nowadays the role of nuclear science and engineering has become more widely accepted in the quest for carbon net zero. Growing up in Hamilton, Scotland during a time of energy insecurity, Fiona was determined to understand more about why her school lacked the energy to heat up all of the classrooms or why there were power cuts causing her to have to do ...
Sep 09, 2024•26 min•Transcript available on Metacast Dr Sheila Willis is a forensic scientist who was Director General of Forensic Science Ireland for many years. She has spent her life using science to help solve cases, working on crime scenes and then analysing material in the lab, and presenting scientific evidence in court. It’s a complicated business. Forensic science relies on powerful technology, such as DNA analysis, but it cannot be that alone - it’s also about human judgement, logical reasoning and asking the right questions. It is these...
Sep 02, 2024•28 min•Transcript available on Metacast Professor Charles Godfray, Director of the the Oxford Martin School tells Jim Al-Kahlili about the intricate world of population dynamics, and how a healthy obsession with parasitic wasps might help us solve some of humanity's biggest problems, from the fight against Malaria to sustainably feeding a global community of 9 billion people.
Aug 26, 2024•28 min•Transcript available on Metacast Sir Jonathan Van-Tam, or ‘JVT’ as he's arguably better known, first came to widespread public attention in his role as Deputy Chief Medical Officer during the Covid-19 pandemic. But even before that, Jonathan had built an impressive career based on a long-held fascination with respiratory illness and infectious diseases. He’s worked across the public and private sectors, contributing significantly to improving our understanding of influenza and treatments to address such viruses. It’s hard to be...
Aug 19, 2024•28 min•Transcript available on Metacast 
