Dr. Ken Milne: What is the evidence for evidence-based medicine?

Episode description

Dr. Ken Milne has been working clinically as an emergency physician for 27 years and is an Associate Professor in the Department of Medicine (Division of Emergency Medicine) and Department of Family Medicine. Dr. Milne is passionate about skepticism and critical thinking. He is the creator of the knowledge translation project, The Skeptics’ Guide to Emergency Medicine (TheSGEM). He teachesa evidence-based medicine, clinical epidemiology, critical appraisal and biostatistics at Western University in London, Ontario, and serves as a senior editor of Academic Emergency Medicine. He has no funding from the pharmaceutical or biomedical device industry.  

 Citations 

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  ·      Every-Palmer S, Howick J. How evidence-based medicine is failing due to biased trials and selective publication. J Eval Clin Pract. 2014 Dec;20(6):908-14. doi: 10.1111/jep.12147. Epub 2014 May 12. PMID: 24819404.  

·      Ioannidis JP. Evidence-based medicine has been hijacked: a report to David Sackett. J Clin Epidemiol. 2016 May;73:82-6. doi: 10.1016/j.jclinepi.2016.02.012. Epub 2016 Mar 2. PMID: 26934549.

 ·      Guyatt G. Dave Sackett and the ethos of the EBM community. J Clin Epidemiol. 2016 May;73:75-81. doi: 10.1016/j.jclinepi.2016.02.008. Epub 2016 Mar 2. PMID: 26934550.  

·      Murad MH, Asi N, Alsawas M, Alahdab F. New evidence pyramid. Evid Based Med. 2016 Aug;21(4):125-7. doi: 10.1136/ebmed-2016-110401. Epub 2016 Jun 23. PMID: 27339128; PMCID: PMC4975798.

 ·      Smith GC, Pell JP. Parachute use to prevent death and major trauma related to gravitational challenge: systematic review of randomised controlled trials. BMJ. 2003 Dec 20;327(7429):1459-61. doi: 10.1136/bmj.327.7429.1459. PMID: 14684649; PMCID: PMC300808.

 ·      Hayes MJ, Kaestner V, Mailankody S, Prasad V. Most medical practices are not parachutes: a citation analysis of practices felt by biomedical authors to be analogous to parachutes. CMAJ Open. 2018 Jan 15;6(1):E31-E38. doi: 10.9778/cmajo.20170088. PMID: 29343497; PMCID: PMC5878948.

  ·      Yeh RW, Valsdottir LR, Yeh MW, Shen C, Kramer DB, Strom JB, Secemsky EA, Healy JL, Domeier RM, Kazi DS, Nallamothu BK; PARACHUTE Investigators. Parachute use to prevent death and major trauma when jumping from aircraft: randomized controlled trial. BMJ. 2018 Dec 13;363:k5094. doi: 10.1136/bmj.k5094. Erratum in: BMJ. 2018 Dec 18;363:k5343. PMID: 30545967; PMCID: PMC6298200.