Episode description

We are running out of ammunition against certain infections, as bacteria increasingly evade the antibiotics we’ve relied on for nearly a century. Could bacteriophages – viruses that hunt and kill bacteria – be part of the solution?

In 2019, CrowdScience travelled to Georgia where bacteriophages, also known as phages, have been used for nearly a hundred years to treat illnesses ranging from a sore throat to cholera. Here we met the scientists who have kept rare phages safe for decades, and are constantly on the look-out for new ones. Phages are fussy eaters: a specific phage will happily chew on one bacteria but ignore another, so hunting down the right one for each infection is vital.

Since then, we’ve lived through a pandemic, the medical landscape has been transformed, and interest in bacteriophages as a treatment option is growing throughout the world. We turn to microbiologist Professor Martha Clokie for updates, including the answer to listener Garry’s question: could phages help in the fight against Covid-19?

Contributors: Prof Martha Clokie, University of Leicester Dr Naomi Hoyle, Eliava Phage Therapy Center Prof Nina Chanishvili, Eliava Institute Dr Eka Jaiani, Eliava Institute

Presented by Marnie Chesterton Produced by Cathy Edwards and Louisa Field for the BBC World Service

[Photo:Bacteriophages infecting bacteria, illustration. Credit: Getty Images]