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Episode description
#133 – Manolis Kellis: Biology of Disease
Lex Fridman Podcast
Oct 25, 2020
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3 hr 40 min
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Transcript available on
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Episode description
Manolis Kellis is a computational biologist at MIT. Please support this podcast by checking out our sponsors: - SEMrush:
https://www.semrush.com/partner/lex/
to get a free month of Guru - Pessimists Archive:
https://pessimists.co/
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and use code LEX to get $200 off - BetterHelp:
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to get 10% off EPISODE LINKS: Manolis Website:
http://web.mit.edu/manoli/
Manolis Twitter:
https://twitter.com/manoliskellis
Manolis YouTube:
https://www.youtube.com/channel/UCkKlJ5LHrE3C7fgbnPA5DGA
Manolis Wikipedia:
https://en.wikipedia.org/wiki/Manolis_Kellis
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OUTLINE: Here's the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time. 00:00 - Introduction 08:05 - Molecular basis for human disease 32:04 - Deadliest diseases 37:47 - Genetic component of diseases 46:38 - Genetic understanding of disease 1:02:25 - Unified theory of human disease 1:08:26 - Genome circuitry 1:33:29 - CRISPR 1:45:06 - Mitochondria 1:53:10 - Future of biology research 2:22:46 - The genetic circuitry of disease
