Welcome to "The Science Of" Podcast, where students from the Jackie Robinson Family YMCA sit down with top scientists, doctors, and other leaders in the world of science from the globally renowned UCSD and the UCSD Moores Cancer Center in La Jolla, CA.
In this episode, Riley James, Haydee Arancibia-Hardwick, and Margaux Stack-Babich sit down to discuss THE SCIENCE OF CANCER CELL SIGNALING with Dr. Matt Hangauer, the Principal Investigator of the Hangauer Lab at UC San Diego as well as an Assistant Professor with the UCSD Department of Dermatology. The Hangauer Lab explores the biology of cancer persister cells, a prevalent yet poorly understood subpopulation of cancer cells that reversibly enter into a quiescent, pro-survival cell state to survive drug treatments. By uncovering the molecular mechanisms of key events such as drug stress-induced mutagenesis, survival of CD8 T cell attack, and suppression of apoptosis, the Hangauer Lab seeks to identify novel therapeutic targets to prevent acquired resistance.
Enjoy this episode and get your PODucation on!!
TIME | DISCUSSION 02:48 | About Dr. Hangauer 04:12 | Rapid Fire Questions 10:35 | The destiny of his career choice 15:34 | Cancer cell signaling 18:00 | Disrupting cell signaling 25:04 | Persister cells 27:24 | What is it like running a lab? 30:45 | Futuristic questions 33:54 | AI Emperor for a day...what would he do? 35:25 | Advice to young science students
Enjoy this excellent conversation, the "Rapid Fire" questions, and insights on a topic which is top of mind around the world.
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"The Science Of" podcast series is brought to you by the UCSD Moores Cancer Center, SchoolCAST, a division of Cloudcast Media, and the Jackie Robinson Family YMCA.
Episode 17 | The Science Of Cancer Cell Signaling | Dr. Matt Hangauer, UCSD Dept. of Dermatology; Principal Investigator, Hangauer Lab | The Science Of podcast - Listen or read transcript on Metacast