In the new EU-UK deal, the UK is to be an associate member of the latest EU research funding round, known as Horizon Europe. Costing around £2bn to take part, what can UK scientists now do and what has changed? UKRI CEO Otteline Leyser and the Wellcome Trust EU specialist Beth Thompson discuss ways in which UK researchers are breathing a sigh of relief. Of all the ways the UK can now diverge from the EU, DEFRA is currently holding an open consultation on whether to tweak the current GMO regulati...
Jan 14, 2021•33 min•Transcript available on Metacast After the decision by the UK government last week to change the spacing between dosings of vaccine from the recommended 3 weeks to 12 weeks, immunologists around the world have been discussing with some urgency the wisdom of such a move. The FDA and the WHO are deeply sceptical, and the manufacturers have distanced themselves to some extent, by cautioning not to deviate from the regime tested in last year's phase III trials. The thinking behind the move is to get more people injected with a sing...
Jan 07, 2021•39 min•Transcript available on Metacast As a new decade ticks over, Dr Adam Rutherford, Professor Alice Roberts and Professor Brian Cox look back on a decade of science that has transformed perceptions of our medicine, our history and our universe. From advances in genetics that have brought personalized medicine to reality, and revealed the ghosts of ancestral human species never before identified, to quantum computing lessons that hint at the nature of existence and causation throughout the universe, it has been an interesting time....
Dec 31, 2020•39 min•Transcript available on Metacast Nobody could have failed to notice the one story dominating the science news this year - but what about the discoveries that have been overshadowed in 2020? This week, Dr Adam Rutherford eschews all mentions of the pandemic as he invites dinosaur researcher Dr Susie Maidment, climate scientist Dr Tamsin Edwards and astrophysicist Dr Emma Chapman to share their science highlights of the year. We journey to the moon and beyond to discuss the many missions that have been blasting and grabbing bits ...
Dec 24, 2020•32 min•Transcript available on Metacast Dr Alex Lathbridge with your peek at the week in science. This week in the House of Commons Matt Hancock announced a new variant in the Covid virus, discovered to be spreading through the south east of the UK. As Professor Jonathan Ball of the University of Nottingham describes, there have been many slight mutations and changes to the DNA in the virus since it first emerged, and most are of no added danger. But it is important that new ones - and new combinations of them - are tracked through co...
Dec 17, 2020•33 min•Transcript available on Metacast Dr Alex Lathbridge brings you the week in science. As the first COVID vaccines are delivered this week hastening the first glimmers of a return to normal life, is it too soon to be thinking about other future threats to humanity? James Arbuthnot, chair of a House of Lords select committee tasked to look at risk planning, and fellow committee member Martin Rees discuss their meeting this week and the assessment of the scientists invited to share their interpretations of future threats like AI, so...
Dec 10, 2020•37 min•Transcript available on Metacast Has one of the biggest problems in biology been solved by AI? Dr Alex Lathbridge brings you the week in science. This week google's Deep Mind team presented results of their latest efforts at cracking the 50 year old problem of Protein Folding. AlphaFold has built on previous success at predicting the 3D structures of biological proteins from just knowing the sequence of amino acids of which it is made. It is a computational problem that thousands of researchers around the world have been trying...
Dec 03, 2020•37 min•Transcript available on Metacast Last weekend a joint European-US satellite blasted into space to begin its mission - monitoring the oceans back here on earth. Sentinel 6 Michael Freilich is one of a long line of satellites and has a striking design – appearing like a bright gold farmyard barn with a big pitched roof. Anand Jagatia speaks to Dr Ralph Cordey at Airbus Space and Defence about the latest design iteration and the technology on-board. Oceanographer Professor Penny Holiday from the National Oceanography Centre explai...
Nov 26, 2020•30 min•Transcript available on Metacast Earlier this month, the government rolled out a pilot in Liverpool for ‘Operation Moonshot’, their proposal to spend £100 billion pounds to regularly test the entire UK population for SARS CoV 2. Anand Jagatia speaks to screening expert Dr Angela Raffle and medical test evaluator Professor Jon Deeks from the University of Birmingham. They share their concerns about the scheme and the benefits it may bring. A year ago, BBC Inside Science helped launch the Big Compost Experiment, a citizen science...
Nov 19, 2020•31 min•Transcript available on Metacast Scientists this week announced hopeful results in two of the big COVID-19 vaccination trials. Trudie Lang, Professor of Global Health at the Nuffield Department of Medicine, Oxford, describes some of the methodology used, what the efficacy statistic means, and how the novel approach of inserting mRNA rather than deactivated virus parts, is so exciting. Prof Charles Cockell has been investigating how bacteria might be grown in space on lumps of asteroid to extract precious minerals, and as Kim Mc...
Nov 12, 2020•36 min•Transcript available on Metacast We know that children can catch the SarsCov2 virus, even though adverse side effects are incredibly rare. But what isn't clear is how likely they are to transmit the virus? If you’re a parent, are you in danger of catching the virus, maybe brought home from school by your child? A large study, using the anonymised health experiences of around 12 million adults registered with GPs in England, has just been published that explores that question. Dr Laurie Tomlinson, of London School of Hygiene and...
Nov 05, 2020•31 min•Transcript available on Metacast Marnie Chesterton presents an update on the week's science. Behind your eyes, above your mouth but below the brain, two 3cm saliva glands have been hiding since anatomy began. So reports a new study by Matthijs Valstar and Wouter Vogel of The Netherlands Cancer Institute. They describe to Marnie how they found these hitherto unnoticed glands, and importantly how knowledge of these will help people treated for head and neck cancers to get on with their lives in the future. It may be that radiothe...
Oct 29, 2020•34 min•Transcript available on Metacast If you contracted COVID will you then be protected from further infections and illness from SARS-CoV-2 in the future? We’re starting to hear about cases of people being infected by the novel coronavirus for a second time. A handful of these cases have been published in peer reviewed journals. Nottingham University’s Professor of Virology Jonathan Ball discusses how big the problem of reinfection might be. Is it likely to be a common event which could hamper efforts to bring the pandemic under co...
Oct 22, 2020•34 min•Transcript available on Metacast From the very start of the COVID pandemic, test and trace has been the mantra. But here in the UK it was started, then abandoned as the number of cases rose too high to manage. It’s now been reintroduced and we’re all being encouraged to download the ‘NHS COVID-19’ phone app which can detect whether you’ve been near an infected person using Bluetooth technology. How have other countries around the world been managing to find, test, trace, isolate and support (FTTIS) their COVID patients? And wha...
Oct 15, 2020•40 min•Transcript available on Metacast Claudia Hammond looks at the neuroscience behind our sense of touch. Why does a gentle touch from a loved one make us feel good? This is a question that neuroscientists have been exploring since the late 1990's, following the discovery of a special class of nerve fibres in the skin. There seems to be a neurological system dedicated to sensing and processing the gentle stroking you might receive from a parent or lover or friend, or that a monkey might receive from another grooming it. Claudia tal...
Oct 08, 2020•34 min•Transcript available on Metacast There are few images as awe-inspiring as those of the deep cosmos. Photos of the stars, galaxies, constellations and cosmic nebulae are difficult to improve on, but a new book might have done just that, by making them stereoscopic. David Eicher, Editor-in-Chief of Astronomy Magazine teamed up with astro-photographer J. P. Metsavainio, all engineered by astrophysicist and stereoscope enthusiast Dr Brian May, and they’ve created the first ever book on nebulae in 3-D, It’s called ‘Cosmic Clouds 3-D...
Oct 01, 2020•37 min•Transcript available on Metacast The Royal Society’s Insight Investment Science Book Prize’s shortlist has just been announced. Over the next few weeks, Marnie and Adam will be chatting to the six authors in line for the prestigious prize. They’ll be getting a guided tour of ‘The Body – a Guide for Occupants’ with Bill Bryson; Discussing ‘Life According to Physics’ with Jim Al Khalili; Explaining Humans: Discovering ‘What Science Can Teach Us about Life, Love and Relationships’ with Camilla Pang; Linda Scott will be exploring ‘...
Sep 24, 2020•35 min•Transcript available on Metacast As it starts to get colder and we crank up the central heating in our homes, what will the effect be on the SARs-CoV-2 virus? As a respiratory virus like the common cold and influenza, will the coronavirus have a distinct season and will the incidence of COVID get worse in the winter? A pre-print study of over 7000 hospitalised patients across Europe and China during the early days of the pandemic plotted severity of the disease with outside temperature. In European countries as we came out of w...
Sep 17, 2020•31 min•Transcript available on Metacast Vaccination has eradicated smallpox, a disease that decimated populations through the 20th century. Polio is almost gone too, and measles is no longer the pervasive childhood threat it once was. It’s clear that vaccination is our best tool to halt the threat of SARS CoV 2, and allow the return to a less restricted way of life. But it takes time to develop and test vaccines although the technologies used to create them have moved on significantly over the last few decades. Professor Jonathan Ball...
Sep 10, 2020•29 min•Transcript available on Metacast Skulls give researchers a great deal of insight into how an animal might have evolved, and skulls can be sensibly compared between species and groups of animals. The 10,000 species of bird around the world are what’s left of an even more diverse group, the dinosaurs. But research on their skulls has revealed that despite the birds’ exceptional diversity, they evolve far more slowly than their dinosaur relatives ever did. This is one of the findings of a huge skull mapping project at the Natural ...
Sep 03, 2020•28 min•Transcript available on Metacast Over the next couple of weeks almost all children in the UK will be back to school. But the pandemic hasn’t ended, and we are far from having a complete understanding of how this virus works, including how it is transmitted and how it affects younger people. Pretty much everyone is in agreement that kids need to be back at school, as the costs of not being physically in classrooms are great - for the education of kids, for their mental health, and for the finances of parents needing to work. But...
Aug 27, 2020•32 min•Transcript available on Metacast Red clay bricks are among the most ubiquitous building materials worldwide. Julio D'Arcy, a chemist at Washington University in St. Louis, Missouri, describes to Adam Rutherford how he and his team have turned ordinary house bricks into energy storage units that can power home electronic devices – thanks to the red iron oxide (rust) pigment and a conductive plastic nano-material infused into the bricks These new ‘smart bricks’ can be charged to hold electricity a bit like a battery. As the pande...
Aug 20, 2020•28 min•Transcript available on Metacast COVID19 is a chilling reminder of how pathogens from animals can jump into humans. But it’s not the first time. SARS, Ebola, West Nile virus and bubonic plague are all serious infectious diseases that sat in a host species before crossing to us. But what causes this to happen? Individual case studies suggest that we are partly to blame in the way we use the land, either through urbanisation or agriculture. But how widespread is this, and do our global patterns of land use systematically put us a...
Aug 13, 2020•28 min•Transcript available on Metacast Adam reveals new research which overturns received wisdom about how sperm swim. More than three centuries after Antonie van Leeuwenhoek peered down his early microscope to observe human sperm or ‘animalcules’ swimming with a ‘snakelike movement, like eels in water’, high-tech observations now reveal that this was, in fact, an optical illusion. Hermes Gadelha from Bristol University used 3D microscopy, a high-speed camera and mathematics, to reconstruct the true movement of the sperm tail. Much t...
Aug 06, 2020•28 min•Transcript available on Metacast The Science Museum Group looks after over 7.3 million items. As with most museums, the objects you see on display when you visit are only the tip of the iceberg of the entire collection. Up until now, many of the remaining 300,000 objects have been stored in Blythe House in London. But now the collection is being moved to a purpose-built warehouse in Wiltshire. The move is a perfect opportunity for curators to see what’s there, re-catalogue long hidden gems and to conserve and care for their tre...
Jul 30, 2020•32 min•Transcript available on Metacast A pre-print is a way for scientists to get their work out quickly for other scientists to comment on and debate. But pre-prints are not peer reviewed; they have not undergone the scrutiny of reviewers and journal editors. They're generally seen as a good thing, but are just a step on the way for science to be verified and published. But it's important to note that the science can be wrong or sloppy in pre-prints, so they have never really been part of the process by which science is disseminated...
Jul 23, 2020•32 min•Transcript available on Metacast Science is all about self-reflection. Scientists constantly check themselves, share their work, and check each other’s data. But how robust is the science upon which civilisation is built, the science which has mapped genomes, cured diseases, split atoms and sent people to the moon? Adam talks to Stuart Ritchie, a psychologist from Kings College London, about his new book Science Fictions which explores everything from biases and human fallibility, to outright fraud. He also talks to microbiolog...
Jul 16, 2020•28 min•Transcript available on Metacast Is the UK losing its way when it comes to satellite navigation? There's GPS from the US, but other countries and regions, including Russia, China, India and Japan, either have, or are building, satellite navigation systems of their own. The EU has Galileo, but with Brexit, Britain is no longer involved. The Government has announced that it’s just acquired a satellite technology company called OneWeb. It’s primary role is enhanced broadband, but there’s talk of adding in a navigation function to ...
Jul 09, 2020•34 min•Transcript available on Metacast As we’re beginning to understand more about SARS-CoV-2, the virus that causes COVID-19, we’re hopefully starting to get some clues on how to deal with the next viral pandemics, and even look at ways of stopping them from happening. To do this, we have to go back to where the virus jumped from its animal host into humans. Like this current coronavirus, many of the pandemic viruses (SARS, MERS HIV, Ebola…to name a few) are zoonotic diseases. They start in wild animals and evolve to jump to humans ...
Jul 02, 2020•28 min•Transcript available on Metacast Adam Rutherford is back to celebrate the 20th anniversary of one of the most ambitious and revolutionary scientific endeavours of all time - the Human Genome Project. Its scope and scale was breath-taking, set up to read every one of the 3 billion nucleotides, or letters of genetic information, contained within the DNA in every cell of the human body. It took seven years, hundreds of scientists, cost almost $3 billion and, amazingly, came in under budget and on time. Adam reflects back on that m...
Jun 25, 2020•32 min•Transcript available on Metacast 
