Send us a text Is cultivated meat the food of tomorrow or just a passing trend? In this episode, we dive deep with Steven Lang, an expert in the field of cultivated meat. Steven sheds light on the intricate process of creating meat in the lab, the challenges faced, and the potential future of this innovative industry. Key Takeaways: Precision in Analytics: Discover how cutting-edge sensory analytics are crucial for developing cultivated meat that mimics traditional meat's texture and taste....
May 23, 2024•15 min•Transcript available on Metacast Send us a text How can you create an environment suitable for shear-stress-sensitive cells that results in higher cell concentrations and superior quality? Essentially, bionic bioreactors revolutionize this process, changing the game rules with their ability to facilitate bubble-free gas exchange. Join us in this episode as we unravel the groundbreaking innovations in bioreactor technology with our guest, Patrick Bongartz, CEO of BioThrust and the visionary mind behind stress-free cell cultivati...
May 21, 2024•23 min•Transcript available on Metacast Send us a text How can you create an environment suitable for shear-stress-sensitive cells that results in higher cell concentrations and superior quality? Essentially, bionic bioreactors revolutionize this process, changing the game rules with their ability to facilitate bubble-free gas exchange. Join us in this episode as we unravel the groundbreaking innovations in bioreactor technology with our guest, Patrick Bongartz, CEO of BioThrust and the visionary mind behind stress-free cell cultivati...
May 16, 2024•19 min•Ep 54•Transcript available on Metacast Send us a text How can you provide stress-free cultivation conditions to achieve higher cell concentrations and quality? In a nutshell, bionic bioreactors and thus change bubble-free gas exchange change the game. Join us as we delve into the future of biotech with our guest, Patrick Bongartz, CEO of BioThrust and an expert in innovative bioreactor design. Key Highlights: Unveil the groundbreaking "artificial lung," a marvel of engineering that decouples mixing and gas transfer, enablin...
May 14, 2024•18 min•Transcript available on Metacast Send us a text Does the process of commercializing cell and gene therapies seem complex and unclear to you? Dive deep into the groundbreaking world of cell and gene therapies with our guest, Wajiha Ali, a strategy expert who believes in bridging the gap between research and commercialization with data, as we unravel the complexities of bringing life-saving therapies to patients. From cutting-edge technologies to innovative collaboration models, we explore the future landscape of these transforma...
May 09, 2024•26 min•Transcript available on Metacast Send us a text Are you finding the path to commercializing cell and gene therapies complex and uncertain? Join us as we explore this intricate landscape with our guest, Wajiha Ali. As a strategy expert who believes in bridging the gap between research and commericalization with data who she will guide us through the challenges, victories, and vital strategies for successfully bringing these cutting-edge therapies to market. Key Highlights: Discover the amplified complexity of cell and gene thera...
May 07, 2024•19 min•Transcript available on Metacast Send us a text In the second part of "Decode Bioprocess Success: The Art of Stakeholder Management," we delve deeper into the strategies for effective stakeholder management in bioprocess development. Through a step-by-step approach, we explore how to identify, classify, and engage with stakeholders to ensure project success. Key highlights: Learn how to create a stakeholder management plan tailored to the unique needs and interests of each stakeholder group. Discover the power interes...
May 02, 2024•11 min•Ep 50•Transcript available on Metacast Send us a text In this episode, we embark on a journey to uncover the essential strategies for navigating stakeholder relationships in bioprocess CMC development projects. We delve into the critical role of stakeholders in bioprocess development and how their engagement can determine the success or failure of a project. Drawing from real-life experiences and insights, we explore the importance of understanding stakeholder needs, interests, and power dynamics. Discover why stakeholder management ...
Apr 30, 2024•17 min•Transcript available on Metacast Send us a text Unlock the secrets to cost-efficient antibody therapeutics with Brian Kelley, Senior Vice President of Process Development at VIR Biotechnology. In this illuminating episode, industry expert Brian Kelley shares invaluable insights into driving down manufacturing costs while maintaining quality and accessibility. From optimizing batch sizes to maximizing titers, discover practical strategies to streamline the process economics of antibody development. Key Takeaways: Scale Matters: ...
Apr 25, 2024•19 min•Transcript available on Metacast Send us a text Join us in this enlightening episode as we explore process economics with industry expert Brian Kelley. He is the Senior Vice President of Process Development at VIR Biotechnology. Unraveling the mysteries of cost management in antibody therapeutics, Brian sheds light on the intricate challenges faced by biotech scientists and engineers. Key Highlights: Discover the nuanced interplay between technical and cultural obstacles in process development. Navigate the labyrinth of cost dr...
Apr 23, 2024•17 min•Transcript available on Metacast Send us a text Dive into the future of food with our latest episode, "From Lab to Table: The Science Behind Cultivated Meat." With our guest, Petra Hanga, a Lecturer in Biochemical Engineering at University College London and Chief Scientific Officer of Quest Meat Ltd., we unravel the secrets behind this groundbreaking technology. Key highlights: 1. Discover how stem cells revolutionize the production of cultivated meat, providing a scalable solution for creating muscle, fat, and conne...
Apr 18, 2024•26 min•Transcript available on Metacast Send us a text Dive into the fascinating world of cultivated meat with our guest, Petra Hanga, Lecturer in Biochemical Engineering – Cellular Agriculture at University College London and the Chief Scientific Officer of Quest Meat Ltd. In this episode, Petra sheds light on the intricacies of developing cultivated meat and reveals the key hurdles biotech scientists face. Highlights: Learn how scientists tackle the complexity of replicating animal meat, ensuring a truly authentic taste and texture ...
Apr 16, 2024•14 min•Transcript available on Metacast Send us a text Does uncovering the secrets of glycan engineering feel like navigating a maze of molecular complexity? In this captivating continuation of our exploration into the world of glycan engineering, we delve deeper into groundbreaking innovations and the crucial role of analytics in ensuring consistent quality. Henning von Horsten, Professor of Industrial Bioengineering at HTW Berlin (University of Applied Sciences in Berlin), shares the fascinating story behind a groundbreaking technol...
Apr 11, 2024•18 min•Transcript available on Metacast Send us a text Does unlocking the secrets of glycan engineering seem like navigating a labyrinth of molecular complexity? In this episode, we delve into the pivotal role of glycans as critical quality attributes (CQAs) in biotherapeutics. Henning von Horsten, Professor of Industrial Bioengineering at HTW Berlin (University of Applied Sciences in Berlin), sheds light on the art and science of glycan engineering and analysis. Key highlights: Discover various methods scientists are utilizing to imp...
Apr 09, 2024•23 min•Ep 43•Transcript available on Metacast Send us a text Hey, fellow scientists! Do you find yourself buried under an avalanche of tasks, unsure which one truly matters? If you're tired of the chaos and want to reclaim control of your time and energy, stick around. Today, we're unlocking the secrets of Essentialism, tailor-made for busy biotech scientists like you. We discuss the importance of focusing on the vital few tasks that contribute significantly to your goals, celebrating small wins, and protecting your time. We also ...
Apr 04, 2024•13 min•Transcript available on Metacast Send us a text Hey, fellow scientists! Do you find yourself buried under an avalanche of tasks, unsure which one truly matters? If you're tired of the chaos and want to reclaim control of your time and energy, stick around. Today, we're unlocking the secrets of Essentialism, tailor-made for busy biotech scientists like you. We discuss the importance of focusing on the vital few tasks that contribute significantly to your goals, celebrating small wins, and protecting your time. We also ...
Apr 02, 2024•15 min•Ep 41•Transcript available on Metacast Send us a text Explore the intricate world of perfusion and its sustainability challenges in the part 2 of this episode. Dive into the operational side of managing vast quantities of media production and storage, and discover smart strategies to address these challenges. Jochen Sieck, Director of Cell Culture Media and Process Development at Merck Life Science, discusses the distinction between facility designs for batch and perfusion bioreactors, shedding light on the need for extensive tank fa...
Mar 28, 2024•15 min•Transcript available on Metacast Send us a text Explore perfusion processes and sustainability with our guest, Jochen Sieck, Director of Cell Culture Media and Process Development at Merck Life Science. Learn about the evolution of perfusion methodologies, its historical roots in addressing product stability, and its recent return to continuous and integrated manufacturing. Jochen discusses the economic and strategic reasons behind perfusion's resurgence, emphasizing the need for flexible, smaller-scale facilities. Key Lea...
Mar 26, 2024•24 min•Transcript available on Metacast Send us a text In part 2 of this insightful episode, we embark on a journey into the intricate world of biotech purification processes. Our guest, Wei Zhang, DSP Group Head at A*STAR Bioprocessing Technology Institute, delves into three key modalities, shedding light on the challenges and advancements in virus, RNA, and traditional vaccine purification. You will learn: Learn how to master the purification of viruses Get an overview of the advancements in RNA purification techniques: the evolutio...
Mar 21, 2024•17 min•Transcript available on Metacast Send us a text In this episode, Wei Zhang, DSP Group Head at A*STAR Bioprocessing Technology Institute, delves into the complexities of purification. Wei’s team pioneers bioprocessing processes for diverse biotherapeutics. You will gain valuable insights into the intricate challenges and innovative solutions in bioprocessing purification. You will learn: Master scale-up challenges Understand how you can ensure product stability Get an overview of the advancements in purification techniques The c...
Mar 19, 2024•20 min•Transcript available on Metacast Send us a text Welcome back to the second part of our insightful interview with Joel Eichmann, Managing Director of Green Elephant Biotech. In this episode, we delve deeper into the technical aspects of adherent cell expansion systems, explore sustainable biotech practices, and discuss key considerations for cost-efficient and environmentally friendly bioprocessing. Key Insights: How to adopt a strategic approach to adherent cell culture development Delve into the intricacies of scaling up adher...
Mar 14, 2024•18 min•Transcript available on Metacast Send us a text Get ready for a deep dive into the world of bioprocess development as Joel Eichmann, Managing Director of Green Elephant Biotech, shares his expertise on smart strategies for adherent cell culture . Join us as we unravel the intricacies of adherent cell culture and discover the innovative strategies shaping the future of bioprocess development. You’ll get: Acquire a comprehensive understanding of the key challenges in developing an adherent cell culture process. Gain a fresh persp...
Mar 12, 2024•19 min•Transcript available on Metacast Send us a text Uncover the secrets of successful innovators, including Steve Jobs, Elon Musk, and Thomas Edison, in this enlightening episode of our podcast. We dive deep into the habits that set these trailblazers apart and fuel their innovative spirit. Key learnings include: The power of curiosity and how it leads to groundbreaking ideas and improvements. The importance of connecting the dots to gain new insights and see invisible relationships. The role of risk-taking in pushing boundaries an...
Mar 07, 2024•11 min•Ep 34•Transcript available on Metacast Send us a text Uncover the secrets of successful innovators, including Steve Jobs, Elon Musk, and Thomas Edison, in this enlightening episode of our podcast. We dive deep into the habits that set these trailblazers apart and fuel their innovative spirit. Key learnings include: The power of curiosity and how it leads to groundbreaking ideas and improvements. The importance of connecting the dots to gain new insights and see invisible relationships. The role of risk-taking in pushing boundaries an...
Mar 05, 2024•11 min•Transcript available on Metacast Send us a text Discover the hurdles and breakthroughs in glycoengineering, including the high costs of activated sugars. Thomas Rexer, CTO of eversyn, a spin-off of the Max Planck Institute Magdeburg, unveils eversyn's multi-step biocatalysis process, designed to significantly drive down costs and make in vitro glycoengineering more accessible on a large scale. Key Insights: Uncover the power of multistep biocatalysis in driving down costs and making in vitro glycoengineering more accessibl...
Feb 29, 2024•17 min•Ep 32•Transcript available on Metacast Send us a text Get ready for a crash course in glycoengineering as Thomas Rexer, CTO of eversyn, a spin-off of the Max Planck Institute Magdeburg, breaks down the significance of modifying glycans in biopharmaceuticals. Explore the science behind glycoengineering and its potential to enhance the properties of therapeutic proteins. Key Insights: Unlock new frontiers in glycoengineering Explore the potential of glycoengineering to revolutionize biopharmaceuticals Ensure seamless integration of gly...
Feb 27, 2024•18 min•Transcript available on Metacast Send us a text In our insightful second part of the conversation, we broaden our perspective to delve into the various modalities within the biotech industry, highlighting the unique and shared aspects of process development and scale-up. Neil Templeton, the Director of Upstream Process Development at Solid Biosciences, passionately articulates his commitment towards making gene therapy more accessible. He does this by outlining strategic solutions to reduce the costs of development and manufact...
Feb 22, 2024•15 min•Transcript available on Metacast Send us a text In this enlightening episode, we're joined by Neil Templeton, Director in Upstream Process Development at Solid Biosciences, who pulls back the curtain on the intricate world of bioprocess development and manufacturing. Neil delves into the shifting paradigms of the industry, sharing his expert insights on overcoming the unique challenges that surface when transitioning from R&D to GMP production. This episode is packed full of invaluable knowledge that's crucial for...
Feb 20, 2024•23 min•Transcript available on Metacast Send us a text Tackling bioprocess development and scale-up can be complex. While the science might be challenging, project management within biotech doesn't have to be. In this engaging episode, we'll guide you on how to streamline your CMC development, demystifying the complexities of project planning and execution. Here's what you'll gain: Discover the secret to 'Successful Planning,' - a strategy to ensure your projects are well-organised, resource-smart, and ti...
Feb 15, 2024•13 min•Transcript available on Metacast Send us a text Bioprocess development and scale-up are complex. Science may give you headaches, but biotech project management should not. In this riveting episode, you'll learn how to simplify your CMC development, guiding you through the maze of project planning and execution. Key Takeaways: Uncover how to "Plan for Success," ensuring your projects are well-structured, resource-efficient, and delivered on time. Learn the importance of "Evaluating the Scalability Potential,&...
Feb 13, 2024•16 min•Ep 27•Transcript available on Metacast 
