Loneliness is a public health crisis affecting people of all ages.This week on Possible, Reid and Aria sit down with someone using AI to bridge generational gaps and combat the loneliness epidemic. Dana Griffin is co-founder and CEO of Eldera, a global platform using AI to foster intergenerational connections. Raised by her grandparents and mentored by older adults throughout her life, Dana is on a mission to help people see aging as an asset. Dana shares how Eldera uses AI to safely and meaning...
Mar 12, 2025•57 min•Ep 9•Transcript available on Metacast Reid reacts to the news of HP acquiring Humane Ai Pin and weighs in on the future of wearable tech, quantum, and copyright law. Plus, AI whiz Parth Patil (formerly Clubhouse’s first data scientist) joins the show to discuss why he’s excited about OpenAI’s Deep Research tool, “vibe coding,” and coding copilots. For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/
Mar 05, 2025•27 min•Ep 8•Transcript available on Metacast How does the rise of AI impact our sense of what’s true? How can humans maintain a degree of individual privacy and unlock the benefits of AI while mitigating potential harms? In this episode, Reid and Aria sit down with data privacy pioneer Latanya Sweeney, Professor of Government and Technology at Harvard; former Chief Technology Officer at the U.S. Federal Trade Commission; and founder of Harvard’s Public Interest Tech Lab and Data Privacy Lab. They discuss the future of privacy protection, t...
Feb 26, 2025•57 min•Ep 7•Transcript available on Metacast Following last week’s chat with former diplomat and author Anja Manuel, Reid talks about the potential benefits of an FDA for AI, the current status of the global race for artificial intelligence, and predicting what’s to come from American AI companies. For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/
Feb 19, 2025•13 min•Ep 6•Transcript available on Metacast Love, dating, and AI — what could go wrong? Or right? In this Valentine’s Day special, Rana el Kaliouby and a series of expert guests explore how AI is reshaping romance. First, Will Wu, Chief Technology Officer at Match Group, gives us a peek at how AI is already at work in apps like Tinder and Hinge, helping users choose their best profile pictures and refining match recommendations. Next, the team at Gottman Inc. shares how AI is being used to improve relationships. Their AI-powered tools ana...
Feb 14, 2025•50 min•Transcript available on Metacast What role can AI play in international diplomacy and national security? In this episode, Reid and Aria sit down with Anja Manuel, a former diplomat, author, and one of the leading voices in AI and foreign policy. She has the unique ability to bridge the gaps between technology, policy and diplomacy. They discuss international AI governance, China, potential threats of bio-terrorism, and the strategic decisions that the US and its allies must make to navigate this complex landscape of innovation ...
Feb 12, 2025•1 hr 1 min•Ep 5•Transcript available on Metacast This week, we're bringing you the introduction of Reid’s new book, Superagency: What Could Possibly Go Right with Our AI Future, which he co-wrote with last week’s Possible guest, Greg Beato. The Superagency audiobook is narrated by voice actor Scott Wallace and converted with Respeecher to Reid’s AI voice. Plus, hear what happens when Reid and Aria load Superagency’s introduction into Google’s NotebookLM and turn the final minutes of the episode over to two AI co-hosts. For more info on the pod...
Feb 05, 2025•30 min•Ep 4•Transcript available on Metacast In an age of increasingly ubiquitous AI, how do we maintain control of our lives and successfully plot our own destinies? In this episode, Reid is in the hotseat alongside writer Greg Beato, discussing this and more in the context of their new book, Superagency. Greg is a seasoned journalist whose work has appeared in the New York Times, Wired, The Washington Post, Reason, Spin, and Slate, to name a few. He and Reid delve into what could possibly go right with our AI future; the cognitive indust...
Jan 29, 2025•58 min•Ep 3•Transcript available on Metacast What new kinds of jobs will AI bring that we never could have imagined before? In this special two-part episode, Reid and Aria explore this question and more with Sierra co-founder and OpenAI chairperson Bret Taylor. Part one features audio from Bret's onstage interview at the 2024 Masters of Scale Summit, where he shared his insights on the voice revolution in AI, the technology’s latest role as a phone customer service agent, and the groundbreaking business opportunities still waiting to be ex...
Jan 22, 2025•1 hr 7 min•Ep 2•Transcript available on Metacast How can we use AI to amplify human potential and build a better future? And what exactly does “AGI” even mean? To kick off Possible’s fourth season, Reid and Aria sit down with world-renowned computer scientist Fei-Fei Li, whose work in artificial intelligence over the past several decades has earned her the nickname “the godmother of AI.” An entrepreneur and professor, Fei-Fei shares her journey from creating ImageNet, a massive dataset of labeled images that revolutionized computer vision, to ...
Jan 15, 2025•44 min•Ep 1•Transcript available on Metacast Pioneers of AI is your weekly guide to the AI frontier. Each week, host Dr. Rana el Kaliouby (AI scientist, investor, author, co-founder of Affectiva) is joined by the leading creators, critics, and thinkers behind mind-blowing technology and asks the important questions about how artificial intelligence is changing the way we live. In this episode: Creating and sharing art is a uniquely human experience. With the rise of AI, creative processes are shifting, but Taryn Southern doesn’t think that...
Dec 25, 2024•37 min•Transcript available on Metacast What does it take to create something the world has never seen before? In this final episode of Artful Intelligence, Reid Hoffman and Chris McLeod explore what it takes to spark a creative revolution with filmmaker Paul Trillo. Using OpenAI’s groundbreaking AI video generator, Sora, Paul directed the world’s first fully AI-generated music video. After gaining early access to Sora, Paul faced a massive creative challenge: How could he use an AI tool known for surreal, dream-like visuals to craft ...
Dec 18, 2024•57 min•Transcript available on Metacast How can you shape the future with AI to create the world you want to live in? Reid Hoffman and Chris McLeod explore this question with Elise Swopes, a trailblazing visual artist and educator blending AI with photography. Currently an evangelist for Adobe, Elise has been a creative force since the early days of Instagram, crafting surreal visuals for brands such as Adidas, McDonald’s, Casamigos, and Sony. But her journey hasn’t been without challenges. From online harassment to personal struggles...
Dec 11, 2024•49 min•Transcript available on Metacast What if you could create the impossible with AI? In this debut episode of Artful Intelligence, Chris McLeod introduces us to Montreal-based filmmaker Malick Lombion, whose groundbreaking technique, Hyperlapse X AI, is redefining video art. Malick combines hyperlapse cinematography with cutting-edge AI tools like DALL-E to compress time, space, and reality into surreal and mesmerizing visuals. Malick pushed AI to its creative limits, proving that human ingenuity and machine learning can work in t...
Dec 04, 2024•52 min•Transcript available on Metacast Would the world be a better place if we all paused to enjoy a square of sustainably-sourced craft chocolate every day? In honor of the Thanksgiving season, Reid and Aria treat Possible listeners to a discussion about chocolate, flavor, and sustainability. Joining them is Spencer Hyman, whose company, Cocoa Runners, sells craft chocolates from sustainability-minded artisan makers around the world. He gets into the difference between flavor and taste, along with the future of personalized nutritio...
Nov 27, 2024•45 min•Ep 31•Transcript available on Metacast Following an inspiring conversation with JusticeText co-founder Devshi Mehrotra, Aria asks Reid about other opportunities for AI to support public infrastructure. Plus, Reid discusses the state of venture funding and OpenAI’s $6.6 billion round. For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/
Nov 20, 2024•13 min•Ep 30•Transcript available on Metacast America’s criminal justice system relies on public defenders to represent anyone without access to a private attorney. But public defenders are chronically under-resourced and overburdened with caseloads. Can technology help lessen that load and, in effect, make the criminal justice system more just? This week’s guest, Devshi Mehrotra, says yes. Devshi is co-founder and CEO of JusticeText, a startup developing AI software to help lawyers search and review case material more efficiently and enhan...
Nov 13, 2024•50 min•Ep 29•Transcript available on Metacast After last week’s wide-ranging discussion with Bill Gates, Aria asks Reid for his take on the work of this philanthropic luminary. Plus, Reid gives a three-part answer to the technology developments he thinks are going to have broad and beneficial applications across many fields. For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/
Nov 06, 2024•9 min•Ep 28•Transcript available on Metacast In this episode of Remarkable People, join host Guy Kawasaki for an illuminating conversation with Reid Hoffman, co-founder of LinkedIn and partner at Greylock. Together, they explore entrepreneurship, politics, and artificial intelligence, offering unique insights into blitzscaling, the future of democracy, and how games shaped his strategic thinking. Hoffman shares candid views on Silicon Valley dynamics, the impact of extreme wealth, and his optimistic vision for AI's role in society. Discove...
Nov 05, 2024•34 min•Transcript available on Metacast Ahead of the U.S. presidential election, we’re bringing you a bonus episode from Reid's Masters of Scale podcast. A few weeks ago, Reid sat down with former President Bill Clinton at the Masters of Scale Summit to talk about the current state of American democracy, polarization, and what’s at stake in this election. Their full, unedited stage conversation is presented in this episode. To hear more conversations like these from Reid Hoffman, subscribe to Masters of Scale wherever you get your pod...
Nov 04, 2024•36 min•Transcript available on Metacast How many lives will be saved with the help of AI over the next decade? Reid and Aria sat down with Bill Gates to discuss his main areas of focus: climate change, energy, global health, and education—and how AI will help transform each of them. Taking a bird’s-eye view of society’s challenges, it’s easy to give in to pessimism. But as one of the most influential people in the world, Bill Gates has a unique perspective on how far humanity has come and what our potential—and timelines—for meaningfu...
Oct 30, 2024•1 hr 11 min•Ep 27•Transcript available on Metacast What does productive collaboration between big tech developers and the rest of the world actually look like? This week, Reid gets into the value of competition, iterative development, learning mindsets, and red teaming in tech and business—in the United States and globally. For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/
Oct 23, 2024•14 min•Ep 26•Transcript available on Metacast How can people in all corners of the world participate in the AI revolution and unlock benefits in their own lives? James Manyika, Senior Vice President of Research, Technology & Society at Google, joins the show to discuss global access to AI and the impact on capitalism, the economy, science, and the workforce. He speaks to Google’s latest AI developments, including tools to warn people about natural disasters like floods and wildfires, along with the virtual research assistant NotebookLM. Rea...
Oct 16, 2024•47 min•Ep 25•Transcript available on Metacast Reid unpacks the decision to appoint Sean White as the leader of Inflection and outlines what makes him uniquely poised to take on this exciting challenge. Plus, Aria asks Reid about the future landscape of LLMs. For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/
Oct 09, 2024•12 min•Ep 24•Transcript available on Metacast How will an empathetic AI interact with humans? What if we used AI not just for its IQ, but its EQ? How do we build the trust to enable it to take agency on our behalf? This week, Reid and Aria sit down with an expert and friend, Sean White to start answering those questions. Sean White is currently the CEO of Inflection AI and is working on expanding the relationship of what AI can do for humans. Sean takes a humanist approach to new technology, and is interested in AI that can go beyond intell...
Oct 02, 2024•42 min•Ep 23•Transcript available on Metacast With Election Day fast approaching, Reid tackles some big questions: Is Silicon Valley leaning increasingly red? How can—and should—the government modernize voting? Is there a place for AI agents in politics? And which party is really best for business right now? For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/
Sep 25, 2024•17 min•Ep 22•Transcript available on Metacast What’s driving some of the greatest political divisions and threats to democracy ahead of the 2024 U.S. presidential election? This week, Reid and Aria attempt to unpack this with someone who specializes in listening to American voters and translating those insights, at scale: Republican political strategist and The Bulwark co-founder/publisher Sarah Longwell. Sarah, who also hosts The Focus Group Podcast, joins the show to talk about her experience listening to everyday voters through focus gro...
Sep 18, 2024•1 hr 12 min•Ep 21•Transcript available on Metacast Reid reflects on his early exposure to AI as an undergraduate at Stanford and on navigating the space between academia and industry. Plus, he and Aria discuss human outcomes of technology—and how human-centered technologists such as Fei-Fei Li, Mustafa Suleyman, and Kevin Scott have helped him keep those outcomes top of mind. For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/
Sep 11, 2024•11 min•Ep 20•Transcript available on Metacast How can scientists leverage AI and machine learning to more effectively research, develop, and deliver new drugs? This week, Reid and Aria talk drug development with renowned computer scientist and executive Dr. Daphne Koller, whose company, insitro, uses machine learning to improve the quality and speed of drug discovery. She addresses several ways AI and ML are already being used to redefine diseases and create better therapeutic interventions. Plus, she shares her experience transitioning fro...
Sep 04, 2024•1 hr 1 min•Ep 19•Transcript available on Metacast This week, Reid veers toward science fiction, tackling big questions including: Is a single mentally-linked network in our future? Can and should humans create other sentient beings? Select mentions: David Brin
Aug 28, 2024•10 min•Ep 18•Transcript available on Metacast