Matt, Chris, and Jen discuss a case series on California’s Extreme Risk Protection Law, the gang discuss why it’s so difficult to talk about science on controversial topics, and Chris gets serious about classical music. Journal club article: Extreme risk protection law study
Oct 22, 2019•1 hr 1 min•Ep 58•Transcript available on Metacast Matt, Chris, and Jen discuss a study on the relationship between sugary drinks and cancer, the gang discuss how to improve nutritional epidemiology, and Jen gets us all up to speed about avocados. Journal club article: Sugary drinks and cancer
Oct 08, 2019•59 min•Ep 57•Transcript available on Metacast Matt, Chris, and Don discuss a study on a new treatment for sickle cell disease, the gang discuss some advances in registered reports, and Matt figures out which celebrity he should publish a paper with. Journal club article: Sickle cell treatment study
Sep 10, 2019•56 min•Ep 56•Transcript available on Metacast Matt, Chris, and Don discuss a study on whether commonly used contraception increases HIV risk, the gang discuss how to improve the communication of science, and Don finally does standup comedy. Journal club article: Contraception and HIV study
Aug 27, 2019•58 min•Ep 55•Transcript available on Metacast Matt, Chris, and Don discuss the relationship between ability to smell and mortality, the gang discuss the role that journals have to play in combating false medical claims, and Matt explains his concerns about the future of sandwiches. Journal club article: Olfaction and mortality study
Aug 13, 2019•54 min•Ep 54•Transcript available on Metacast Matt, Chris, and Don determine whether you really need to walk 10,000 steps per day, the gang discuss a paper that had two discussion sections which came to two different conclusions, and Don enlightens us on whether couples look alike. Journal club article: 10,000 steps study
Jul 30, 2019•56 min•Ep 53•Transcript available on Metacast Matt, Chris, and Don have been traveling recently so for this episode we bring you another collection of the best of Amazing and Amusing. Enjoy!
Jul 16, 2019•53 min•Ep 52•Transcript available on Metacast Matt, Chris, and Don look at the impact of medical scribes on doctor productivity, the gang discuss a journal that only publishes unsurprising results, and Don grosses us out with facts about viruses. Journal club article: Medical scribes study
Jul 02, 2019•52 min•Ep 51•Transcript available on Metacast Matt, Chris, and Don look at a study of the risk of HIV transmission when a person is successfully taking HIV treatment (spoiler: the risk is 0), the gang discuss what a “risk factor” is, and Matt channels his inner Harry Potter. Journal club article: HIV transmission study
Jun 18, 2019•56 min•Ep 50•Transcript available on Metacast As we are nearing our 50th episode we wanted to take a look back at one of our favorites. Enjoy this rebroadcast of the poop pill episode. Journal club article: Fecal transplant study
Jun 04, 2019•54 min•Ep 49•Transcript available on Metacast Matt, Chris, and Don look at how living on the wrong side of a time zone affects your health, the gang discuss when it might be ok to conduct a trial without patient consent, and Matt wines. Journal club article: Time zone study
May 21, 2019•54 min•Ep 48•Transcript available on Metacast Matt, Chris, and Don look at a study of the impact of cannabis use on psychosis, the gang discuss something called ethics dumping, and Chris goes on a rant about naked mole rats. Journal club article: Cannabis study
May 07, 2019•55 min•Ep 47•Transcript available on Metacast Matt, Chris, and Don look at a new treatment for postpartum depression, the gang discuss some statistical pitfalls in personalized medicine, and Chris schools us all on cat behavior. Journal club article: Brexanolone study
Apr 23, 2019•57 min•Ep 46•Transcript available on Metacast Matt, Chris, and Don look at a study of whether complementary medicines during cancer treatment impact survival, the gang discuss when it is ok to self-plagiarize, and Don has some breaking news about cheese. Journal club article: Complementary medicine and cancer study
Apr 09, 2019•51 min•Ep 45•Transcript available on Metacast Matt, Chris, and Don look at yet another study that found no link between the measles mumps rubella vaccine and autism, the gang discuss whether email is making us stupid (stupider?), and Matt has some news about beer. Journal club article: MMR and autism study
Mar 26, 2019•55 min•Ep 44•Transcript available on Metacast Matt, Chris, and Don look at a study among the Amish to look for causes of asthma, the gang discuss an update to Plan S, and Chris notices an interesting pattern around STI transmission. Journal club article: Asthma among the Amish study
Mar 12, 2019•54 min•Ep 43•Transcript available on Metacast Matt, Chris, and Don look at a study that tested whether e-cigarettes are better than traditional approaches for helping people quit smoking, the gang discuss the value of “null” findings, and Matt has a message for cheaters. Journal club article: E-cigarettes study
Feb 26, 2019•49 min•Ep 42•Transcript available on Metacast Matt, Chris, and Don look at a study of a desensitization treatment for those with peanut allergy, the gang discuss whether artificial intelligence will replace us, and Matt learns how quickly he can put us all to sleep with a boring conference talk. Journal club article: Peanut allergy study
Feb 12, 2019•48 min•Ep 41•Transcript available on Metacast Matt, Chris, and Don look at a study that used an antibody to treat Alzheimer’s disease, the gang goes back to the well to talk about conflicts of interest, and Matt tells us the secret to good course evaluations! Journal club article: Alzheimer’s study
Jan 29, 2019•57 min•Ep 40•Transcript available on Metacast Matt, Chris, and Don look at a study using month of birth to explore whether attention deficit hyperactivity disorder is over-diagnosed, the gang discusses a study on how patients feel about having their clinical trial data shared, and Don enlightens us on which Legos taste best. Journal club article: ADHD and month of birth study
Jan 01, 2019•1 hr 2 min•Ep 38•Transcript available on Metacast Matt, Chris, and Don look at a study of the effects of eating organic foods on risk of cancer, the gang discusses the role of data safety and monitoring boards in clinical trials, and Matt gives his shortest amazing and amusing ever. Journal club article: Organic food and cancer study
Dec 18, 2018•1 hr 2 min•Ep 37•Transcript available on Metacast Matt, Chris, and Don look at a study of whether herpes virus is associated with dementia, the gang discusses a new database of retracted studies and what it tells us, and Don gives us the ICD10 codes we never knew we needed. Journal club article: HSV and dementia study
Dec 04, 2018•1 hr 1 min•Ep 36•Transcript available on Metacast Matt, Chris, and Don look at two studies on asthma medication dosing, the gang discusses whether ad hominem attacks on science are more effective than attacks on the science itself, and Matt finally figures out which host is more popular. Journal club articles: Asthma dosing study 1 Asthma dosing study 2
Nov 20, 2018•1 hr 6 min•Ep 35•Transcript available on Metacast Matt, Chris, and Don look at a massive cross-sectional study on the relationship between exercise and mental health, the gang discusses whether critiquing science gives fodder to those who wish to dismiss science, and Don finally solves all our manuscript issues. Journal club article: Exercise and mental health study
Nov 06, 2018•55 min•Ep 34•Transcript available on Metacast Matt, Chris, and Don look at a study that used a unique approach, analyzing observational data like a randomized trial, to look at the effect of a common NSAID on cardiovascular disease, the gang discusses a study attempting (and often failing) to reproduce results originally published in Nature and Science, and Chris, yet again, finds […]
Oct 23, 2018•58 min•Ep 33•Transcript available on Metacast Matt, Chris, and Don look at a trial that focuses on whether melatonin can help people with a sleep disorder, the gang discusses a provocative editorial that says nutritional epidemiology is deeply flawed, and Chris learns the dangers of ignoring Matt’s emails. Journal club article: Melatonin study
Oct 09, 2018•1 hr 1 min•Ep 32•Transcript available on Metacast Matt, Chris, and Don take on a study from China on the relationship between smog and cognitive function, the gang discusses a new policy by EU funders preventing their grantees from publishing in paywalled journals, and Chris insists he gets two Amazing and Amusings. Journal club article: Smog and cognitive function
Sep 25, 2018•54 min•Ep 31•Transcript available on Metacast It’s our one year anniversary! Chris and Don are away this week so rather than have Matt talk to himself, we thought we’d go back and revisit some of our favorite Amazing and Amusing segments from the past year. Thanks for listening and for a great year!
Sep 11, 2018•44 min•Ep 30•Transcript available on Metacast Matt, Chris, and Jen talk about a study of whether low-dose aspirin to prevent vascular events should be weight dependent, the gang revisits placebo effects and wonders if it is all just regression to the mean, and Jen focuses on the empathy of our dogs. Journal club article: Low dose aspirin study
Aug 28, 2018•1 hr 4 min•Ep 29•Transcript available on Metacast Jennifer Rider joins us in the studio as our first ever guest host. Matt, Chris, and Jen discuss a pragmatic trial of smoking cessation, the gang examines the pros and cons of surrogate endpoints, and Chris schools us all on horse dentistry. Journal club article: Smoking cessation trial
Aug 14, 2018•1 hr 6 min•Ep 28•Transcript available on Metacast