Harvey CEO Winston Weinberg explains why success in legal AI requires more than just model capabilities—it demands deep process expertise that doesn’t exist online. He shares how Harvey balances rapid product development with earning trust from law firms through hyper-personalized demos and deep industry expertise. The discussion covers Harvey’s approach to product development—expanding specialized capabilities then collapsing them into unified workflows—and why focusing on complex work like int...
Mar 11, 2025•54 min•Transcript available on Metacast OpenEvidence is transforming how doctors access medical knowledge at the point of care, from the biggest medical establishments to small practices serving rural communities. Founder Daniel Nadler explains his team’s insight that training smaller, specialized AI models on peer-reviewed literature outperforms large general models for medical applications. He discusses how making the platform freely available to all physicians led to widespread organic adoption and strategic partnerships with publi...
Mar 04, 2025•1 hr 5 min•Transcript available on Metacast OpenAI’s Isa Fulford and Josh Tobin discuss how the company’s newest agent, Deep Research, represents a breakthrough in AI research capabilities by training models end-to-end rather than using hand-coded operational graphs. The product leads explain how high-quality training data and the o3 model’s reasoning abilities enable adaptable research strategies, and why OpenAI thinks Deep Research will capture a meaningful percentage of knowledge work. Key product decisions that build transparency and ...
Feb 25, 2025•33 min•Transcript available on Metacast Palo Alto Networks’s CEO Nikesh Arora dispels DeepSeek hype by detailing all of the guardrails enterprises need to have in place to give AI agents “arms and legs.” No matter the model, deploying applications for precision-use cases means superimposing better controls. Arora emphasizes that the real challenge isn’t just blocking threats but matching the accelerated pace of AI-powered attacks, requiring a fundamental shift from prevention-focused to real-time detection and response systems. CISOs ...
Feb 18, 2025•1 hr•Ep 30•Transcript available on Metacast MongoDB product leader Sahir Azam explains how vector databases have evolved from semantic search to become the essential memory and state layer for AI applications. He describes his view of how AI is transforming software development generally, and how combining vectors, graphs and traditional data structures enables high-quality retrieval needed for mission-critical enterprise AI use cases. Drawing from MongoDB's successful cloud transformation, Azam shares his vision for democratizing AI deve...
Feb 13, 2025•44 min•Transcript available on Metacast Stef Corazza leads generative AI development at Roblox after previously building Adobe’s 3D and AR platforms. His technical expertise, combined with Roblox’s unique relationship with its users, has led to the infusion of AI into its creation tools. Roblox has assembled the world’s largest multimodal dataset. Stef previews the Roblox Assistant and the company’s new 3D foundation model, while emphasizing the importance of maintaining positive experiences and civility on the platform. Mentioned in ...
Feb 04, 2025•55 min•Transcript available on Metacast Ioannis Antonoglou, founding engineer at DeepMind and co-founder of ReflectionAI, has seen the triumphs of reinforcement learning firsthand. From AlphaGo to AlphaZero and MuZero, Ioannis has built the most powerful agents in the world. Ioannis breaks down key moments in AlphaGo's game against Lee Sodol (Moves 37 and 78), the importance of self-play and the impact of scale, reliability, planning and in-context learning as core factors that will unlock the next level of progress in AI. Hosted by: ...
Jan 28, 2025•52 min•Transcript available on Metacast Hema Raghavan is co-founder of Kumo, a company that makes graph neural networks accessible to enterprises by connecting to their relational data stored in Snowflake and Databricks. Hema talks about how running GNNs on GPUs has led to breakthroughs in performance as well as the query language Kumo developed to help companies predict future data points. Although approachable for non-technical users, the product provides full control for data scientists who use Kumo to automate time-consuming featu...
Jan 21, 2025•52 min•Transcript available on Metacast Berkeley professor Ion Stoica, co-founder of Databricks and Anyscale, transformed the open source projects Spark and Ray into successful AI infrastructure companies. He talks about what mattered most for Databricks' success -- the focus on making Spark win and making Databricks the best place to run Spark. He highlights the importance of striking key partnerships -- the Microsoft partnership in particular that accelerated Databricks' growth and contributed to Spark's dominance among data scienti...
Jan 14, 2025•1 hr•Transcript available on Metacast Oege de Moor, the creator of GitHub Copilot, discusses how XBOW’s AI offensive security system matches and even outperforms top human penetration testers, completing security assessments in minutes instead of days. The team’s speed and focus is transforming the niche market of pen testing with an always-on service-as-a-software platform. Oege describes how he is building a large and sustainable business while also creating a product that will “protect all the software in the free world.” XBOW sh...
Dec 10, 2024•52 min•Transcript available on Metacast When ChatGPT ushered in a new paradigm of AI in everyday use, many companies attempted to adapt to the new paradigm by rushing to add chat interfaces to their products. Eric has a different take—he doesn’t think chatbots are the right form factor for everything. He thinks “zero-touch” automation that works invisibly in the background can be more valuable in many cases. He cites self-driving cars as an analogy—or in this case, “self-driving money.” Ramp is a new kind of finance management company...
Dec 03, 2024•39 min•Transcript available on Metacast Founded in early 2023 after spending years at Stripe and OpenAI, Gabriel Hubert and Stanislas Polu started Dust with the view that one model will not rule them all, and that multi-model integration will be key to getting the most value out of AI assistants. In this episode we’ll hear why they believe the proprietary data you have in silos will be key to unlocking the full power of AI, get their perspective on the evolving model landscape, and how AI can augment rather than replace human capabili...
Nov 26, 2024•1 hr 3 min•Transcript available on Metacast Clay is leveraging AI to help go-to-market teams unleash creativity and be more effective in their work, powering custom workflows for everything from targeted outreach to personalized landing pages. It’s one of the fastest growing AI-native applications, with over 4,500 customers and 100,000 users. Founder and CEO Kareem Amin describes Clay’s technology, and its approach to balancing imagination and automation in order to help its customers achieve new levels of go-to-market success. Hosted by:...
Nov 19, 2024•52 min•Transcript available on Metacast Can GenAI allow us to connect our imagination to what we see on our screens? Decart’s Dean Leitersdorf believes it can. In this episode, Dean Leitersdorf breaks down how Decart is pushing the boundaries of compute in order to create AI-generated consumer experiences, from fully playable video games to immersive worlds. From achieving real-time video inference on existing hardware to building a fully vertically integrated stack, Dean explains why solving fundamental limitations rather than specif...
Nov 13, 2024•47 min•Transcript available on Metacast Years before co-founding Glean, Arvind was an early Google employee who helped design the search algorithm. Today, Glean is building search and work assistants inside the enterprise, which is arguably an even harder problem. One of the reasons enterprise search is so difficult is that each individual at the company has different permissions and access to different documents and information, meaning that every search needs to be fully personalized. Solving this difficult ingestion and ranking pro...
Oct 29, 2024•45 min•Transcript available on Metacast In recent years there’s been an influx of theoretical physicists into the leading AI labs. Do they have unique capabilities suited to studying large models or is it just herd behavior? To find out, we talked to our former AI Fellow (and now OpenAI researcher) Dan Roberts. Roberts, co-author of The Principles of Deep Learning Theory, is at the forefront of research that applies the tools of theoretical physics to another type of large complex system, deep neural networks. Dan believes that DLLs, ...
Oct 22, 2024•42 min•Transcript available on Metacast NotebookLM from Google Labs has become the breakout viral AI product of the year. The feature that catapulted it to viral fame is Audio Overview, which generates eerily realistic two-host podcast audio from any input you upload—written doc, audio or video file, or even a PDF. But to describe NotebookLM as a “podcast generator” is to vastly undersell it. The real magic of the product is in offering multi-modal dimensions to explore your own content in new ways—with context that’s surprisingly add...
Oct 15, 2024•32 min•Transcript available on Metacast All of us as consumers have felt the magic of ChatGPT—but also the occasional errors and hallucinations that make off-the-shelf language models problematic for business use cases with no tolerance for errors. Case in point: A model deployed to help create a summary for this episode stated that Sridhar Ramaswamy previously led PyTorch at Meta. He did not. He spent years running Google’s ads business and now serves as CEO of Snowflake, which he describes as the data cloud for the AI era. Ramaswamy...
Oct 08, 2024•59 min•Transcript available on Metacast Combining LLMs with AlphaGo-style deep reinforcement learning has been a holy grail for many leading AI labs, and with o1 (aka Strawberry) we are seeing the most general merging of the two modes to date. o1 is admittedly better at math than essay writing, but it has already achieved SOTA on a number of math, coding and reasoning benchmarks. Deep RL legend and now OpenAI researcher Noam Brown and teammates Ilge Akkaya and Hunter Lightman discuss the ah-ha moments on the way to the release of o1, ...
Oct 02, 2024•45 min•Transcript available on Metacast Adding code to LLM training data is a known method of improving a model’s reasoning skills. But wouldn’t math, the basis of all reasoning, be even better? Up until recently, there just wasn’t enough usable data that describes mathematics to make this feasible. A few years ago, Vlad Tenev (also founder of Robinhood) and Tudor Achim noticed the rise of the community around an esoteric programming language called Lean that was gaining traction among mathematicians. The combination of that and the p...
Sep 24, 2024•40 min•Transcript available on Metacast AI researcher Jim Fan has had a charmed career. He was OpenAI’s first intern before he did his PhD at Stanford with “godmother of AI,” Fei-Fei Li. He graduated into a research scientist position at Nvidia and now leads its Embodied AI “GEAR” group. The lab’s current work spans foundation models for humanoid robots to agents for virtual worlds. Jim describes a three-pronged data strategy for robotics, combining internet-scale data, simulation data and real world robot data. He believes that in th...
Sep 17, 2024•49 min•Transcript available on Metacast There’s a new archetype in Silicon Valley, the AI researcher turned founder. Instead of tinkering in a garage they write papers that earn them the right to collaborate with cutting-edge labs until they break out and start their own. This is the story of wunderkind Eric Steinberger, the founder and CEO of Magic.dev. Eric came to programming through his obsession with AI and caught the attention of DeepMind researchers as a high school student. In 2022 he realized that AGI was closer than he had p...
Sep 10, 2024•51 min•Transcript available on Metacast On Training Data, we learn from innovators pushing forward the frontier of AI’s capabilities. Today we’re bringing you something different. It’s the story of a company currently implementing AI at scale in the enterprise, and how it was built from a bootstrapped idea in the pre-AI era to a 150 billion dollar market cap giant. It’s the Season 2 premiere of Sequoia’s other podcast, Crucible Moments, where we hear from the founders and leaders of some legendary companies about the crossroads and in...
Sep 03, 2024•43 min•Transcript available on Metacast Customer service is hands down the first killer app of generative AI for businesses. The reasons are simple: the costs of existing solutions are so high, the satisfaction so low and the margin for ROI so wide. But trusting your interactions with customers to hallucination-prone LLMs can be daunting. Enter Sierra. Co-founder Clay Bavor walks us through the sophisticated engineering challenges his team solved along the way to delivering AI agents for all aspects of the customer experience that are...
Aug 27, 2024•1 hr 13 min•Transcript available on Metacast After AlphaGo beat Lee Sedol, a young mechanical engineer at Google thought of another game reinforcement learning could win: energy optimization at data centers. Jim Gao convinced his bosses at the Google data center team to let him work with the DeepMind team to try. The initial pilot resulted in a 40% energy savings and led he and his co-founders to start Phaidra to turn this technology into a product. Jim discusses the challenges of AI readiness in industrial settings and how we have to buil...
Aug 20, 2024•51 min•Transcript available on Metacast In the first wave of the generative AI revolution, startups and enterprises built on top of the best closed-source models available, mostly from OpenAI. The AI customer journey moves from training to inference, and as these first products find PMF, many are hitting a wall on latency and cost. Fireworks Founder and CEO Lin Qiao led the PyTorch team at Meta that rebuilt the whole stack to meet the complex needs of the world’s largest B2C company. Meta moved PyTorch to its own non-profit foundation...
Aug 13, 2024•39 min•Transcript available on Metacast GithHub invented collaborative coding and in the process changed how open source projects, startups and eventually enterprises write code. GitHub Copilot is the first blockbuster product built on top of OpenAI’s GPT models. It now accounts for more than 40 percent of GitHub revenue growth for an annual revenue run rate of $2 billion. Copilot itself is already a larger business than all of GitHub was when Microsoft acquired it in 2018. We talk to CEO Thomas Dohmke about how a small team at GitHub...
Aug 06, 2024•1 hr 8 min•Transcript available on Metacast As head of Product Management for Generative AI at Meta, Joe Spisak leads the team behind Llama, which just released the new 3.1 405B model. We spoke with Joe just two days after the model’s release to ask what’s new, what it enables, and how Meta sees the role of open source in the AI ecosystem. Joe shares that where Llama 3.1 405B really focused is on pushing scale (it was trained on 15 trillion tokens using 16,000 GPUs) and he’s excited about the zero-shot tool use it will enable, as well as ...
Jul 30, 2024•42 min•Transcript available on Metacast In February, Sebastian Siemiatkowski boldly announced that Klarna’s new OpenAI-powered assistant handled two thirds of the Swedish fintech’s customer service chats in its first month. Not only were customer satisfaction metrics better, but by replacing 700 full-time contractors the bottom line impact is projected to be $40M. Since then, every company we talk to wants to know, “How do we get the Klarna customer support thing?” Co-founder and CEO Sebastian Siemiatkowski tells us how the Klarna tea...
Jul 23, 2024•52 min•Transcript available on Metacast LLMs are democratizing digital intelligence, but we’re all waiting for AI agents to take this to the next level by planning tasks and executing actions to actually transform the way we work and live our lives. Yet despite incredible hype around AI agents, we’re still far from that “tipping point” with best in class models today. As one measure: coding agents are now scoring in the high-teens % on the SWE-bench benchmark for resolving GitHub issues, which far exceeds the previous unassisted basel...
Jul 16, 2024•1 hr 7 min•Transcript available on Metacast 
