Moving from fossil fuels to renewable energy will require huge amounts of copper, lithium, and other metals. Kurt House is the co-founder and CEO of KoBold Metals. The company recently made a huge copper discovery in Zambia, and is looking for other metals in other places. Kurt's problem is this: How do you use AI – machine learning, data science – to find the metals we'll need for the energy transition? See omnystudio.com/listener for privacy information....
Sep 12, 2024•41 min•Season 1Ep. 110
Dalial Freitak and Annette Kleiser are the co-founders of Dalan Animal Health, a company that has brought to market the first vaccine for insects. Their problem is this: How do you turn a discovery about insect immune systems into a vaccine that can protect the bees we need to grow everything from almonds to blueberries? See omnystudio.com/listener for privacy information.
Sep 05, 2024•35 min•Season 1Ep. 109
Sean Hunt is the co-founder and CTO of Solugen, a company that sells around $100 million a year of industrial chemicals. Sean's problem is this: How do you make the chemicals that go into everything around us -- our food, our clothes, our cars -- without using fossil fuels? See omnystudio.com/listener for privacy information.
Aug 29, 2024•39 min•Season 1Ep. 108
Refrigeration is an underrated technology. It completely transformed what billions of people eat every day. Today’s guest, Nicola Twilley, tells the story of refrigeration in her new book, Frostbite: How Refrigeration Changed Our Food, Our Planet, and Ourselves. Topics under discussion include: Why brewers were key drivers of refrigeration technology; the extraordinary technology inside a bag of lettuce; and why the technological frontier in food preservation may mean that we don't need to keep ...
Aug 08, 2024•44 min•Season 1Ep. 107
As generative AI tools improve, it is becoming easier to digitally manipulate content and harder to tell when it has been tampered with. Today we are talking to someone on the front lines of this battle. Ali Shahriyari is the co-founder and CTO of Reality Defender. Ali's problem is this: How do you build a set of models to distinguish between reality and AI-generated deepfakes? See omnystudio.com/listener for privacy information.
Aug 01, 2024•39 min•Season 1Ep. 106
Aluminum is the most abundant metal in the Earth’s crust. It’s cheap, ubiquitous, and surprisingly energy dense. Peter Godart is the co-founder and CEO of Found Energy. Peter's problem is this: How can you use aluminum as a source of clean, renewable energy? See omnystudio.com/listener for privacy information.
Jul 25, 2024•37 min•Season 1Ep. 105
Sarah Rudd is the co-founder and CEO of the soccer analytics company src | ftbl (It’s pronounced “Source Football.”) Sarah’s problem is this: How do you model a sport as fluid and complex as soccer and translate the analytical insights from the model into meaningful changes on the pitch? This is the third and final episode of our series about people who are working at the frontiers of technology to help elite athletes perform better. See omnystudio.com/listener for privacy information....
Jul 18, 2024•41 min•Season 1Ep. 104
Jimmy Buffi is the CEO and co-founder of Reboot Motion, which uses biomechanics to help athletes in Major League Baseball and the NBA. Jimmy's problem is this: How do you turn data about how professional athletes move into knowledge that helps them perform better? This is the second episode of our series about people who are working at the frontiers of technology to help elite athletes perform better. Music: Let's Have Some Fruit (The Fruit Song) by J Buffi See omnystudio.com/listener for privac...
Jul 11, 2024•42 min•Season 1Ep. 103
On the next few episodes of What's Your Problem, Jacob Goldstein is talking with people working at the frontiers of technology to help elite athletes perform better. Today’s guest is Silvia Blemker, a professor of biomedical engineering at the University of Virginia and the co-founder of Springbok Analytics. Silvia's problem is this: How do you combine MRI scans and artificial intelligence to generate new insights that can help both elite athletes and people suffering from diseases that affect t...
Jul 04, 2024•41 min•Season 1Ep. 102
Laura Niklason is the co-founder and CEO of Humacyte. Laura's problem is this: How can you use human cells to create blood vessels that surgeons can pull out of a bag and implant into patients? Although still awaiting FDA approval in the U.S., Humacyte's vessels have already been used to treat wounded soldiers in Ukraine. See omnystudio.com/listener for privacy information.
Jun 27, 2024•42 min•Season 1Ep. 101
As demand for clean energy grows, engineers around the U.S. are working on a new generation of nuclear reactors. These designs reflect how nuclear energy could fit into the power grid – and our lives – in new ways. Yasir Arafat is the Chief Technology Officer at Aalo Atomics. Yasir’s problem is this: How do you mass produce nuclear reactors that are safe, scalable, and cheap? See omnystudio.com/listener for privacy information.
Jun 20, 2024•46 min•Season 1Ep. 100
This week on Risky Business, Nate and Maria discuss whether Supreme Court Justice Sonia Sotomayor should retire, the perils of sports betting among professional athletes, and what the return of Roaring Kitty means for traditional market analysis. Further Reading: “Sonia Sotomayor Should Retire Now” from The Atlantic “Should Sonia Sotomayor Retire?” from Slate “MLB bans Padres’ Tucupita Marcano permanently for betting on baseball” from the NYT “Lifetime bans and careers in tatters – recent sports...
Jun 13, 2024•44 min
Tim Harford is joined by Jacob Goldstein to answer your questions. Does winning the lottery make you unhappy? Is Bitcoin bad for the economy? When does correlation imply causation? And what will Tim and Jacob do when the robot overlords come for their jobs? Enjoy this episode from Cautionary Tales, another Pushkin podcast. See omnystudio.com/listener for privacy information.
Jun 06, 2024•40 min•Season 1Ep. 99
Palm oil is a cheap and remarkably versatile vegetable oil. It’s in a ton of products, from food to cosmetics, detergent, and chewing gum. But producing so much palm oil is really bad for the planet. Shara Ticku is the co-founder and CEO of C16 Biosciences. Shara's problem is this: Can you get yeast to make an oil that is just as useful as palm oil – without clearing land to grow palm trees? See omnystudio.com/listener for privacy information....
May 30, 2024•45 min•Season 1Ep. 98
Last year, the FDA approved a treatment for sickle cell disease using a revolutionary new gene editing technology called CRISPR. Rachel Haurwitz conducted pioneering research on CRISPR as a graduate student. Now she’s the co-founder and CEO of Caribou Biosciences. Rachel's problem is this: How can you improve CRISPR and use it to engineer human immune cells to fight cancer? See omnystudio.com/listener for privacy information.
May 23, 2024•35 min•Season 1Ep. 97
Robert Langer has co-founded dozens of companies, holds over a thousand patents, and is a pioneering figure in drug delivery and tissue engineering. Robert has solved a lot of problems, and is working on many more with his lab at MIT. But there is one big problem that has stuck with Robert his whole career: How do you get discoveries out of the lab and into the world? See omnystudio.com/listener for privacy information.
May 16, 2024•29 min•Season 1Ep. 96
Mateo Jaramillo is the co-founder and CEO of Form Energy. Mateo’s problem is this: How do you build batteries that can provide affordable backup power to the grid for days at a time? As it turns out, the basic technology was developed – and then mostly ignored – over 50 years ago. See omnystudio.com/listener for privacy information.
May 09, 2024•36 min•Season 1Ep. 95
This March, doctors successfully transplanted a pig kidney into a person for the first time in history. Mike Curtis is the CEO of eGenesis, the company that raised the pig whose kidney was used for the procedure. Mike's problem is this: How do you genetically engineer pigs to provide organs – kidneys, hearts, livers – for people? See omnystudio.com/listener for privacy information.
May 02, 2024•36 min•Season 1Ep. 94
Imagine picking up your phone and ordering something from Walmart. Fifteen minutes later, a drone hovers over your yard, lowers your order down to you, and zips away. Adam Woodworth wants this to be so boring you don't even notice. He’s the CEO of Wing, a drone delivery company. His problem is this: How do you turn a flashy idea like a delivery drone into something as ubiquitous as a shopping cart? See omnystudio.com/listener for privacy information....
Apr 25, 2024•38 min•Season 1Ep. 93
Psychedelics are going mainstream. The FDA has approved ketamine for certain patients with depression, and may soon approve MDMA for post-traumatic stress disorder (PTSD). But a fundamental question remains unclear: How do psychedelics work? Gul Dolen is a professor of psychology and neuroscience at UC Berkeley. In a series of experiments, Gul has found evidence of a common mechanism that a wide range of psychedelics use to affect the brain. If Gul is correct, these drugs may be useful not only ...
Apr 18, 2024•32 min•Season 1Ep. 92
Kai Marshland is the co-founder and chief product officer at WindBorne Systems. Kai's problem is this: How do you build weather balloons that can stay in the air for months at a time, and pair the data gathered by the balloons with AI to make weather forecasts that are way better than anything we have today? See omnystudio.com/listener for privacy information.
Apr 11, 2024•35 min•Season 1Ep. 91
Jonathan Hurst is a professor at Oregon State University, and co-founder and chief robot officer at Agility Robotics. Jonathan's problem is this: How do you design a robot that can walk and do useful tasks that companies will pay for? The solution begins with trying to understand how birds walk. See omnystudio.com/listener for privacy information.
Apr 04, 2024•39 min•Season 1Ep. 90
What does sickness sound like? Sometimes it’s obvious, like a cough, sniffle, or stuffy nose. But some conditions cause subtle changes that only a trained ear – or AI – can detect. Dr. Yael Bensoussan is a professor of otolaryngology and the director of the Health Voice Center at the University of South Florida. Her problem is this: How do you build a giant, public database of thousands of voice recordings, and use it to train AI tools that can hear when people are getting sick? See omnystudio.c...
Mar 14, 2024•36 min•Season 1Ep. 89
Cement is, almost literally, everywhere. It is extraordinarily useful, which is why humanity makes 4 billion metric tons of it every year. But cement is also extremely carbon intensive to produce. Leah Ellis is the co-founder and CEO of Sublime Systems. Her problem is this: How can you make cement, at scale, without emitting carbon dioxide? See omnystudio.com/listener for privacy information.
Mar 07, 2024•33 min•Season 1Ep. 88
Sam D'Amico is the founder and CEO of Impulse Labs, a company that makes induction stoves, with a clever twist. Sam’s problem is this: How do you build an electric cooktop that works just as well as gas, and can be installed without having to rewire the house? The solution that Sam found could eventually help transform not only kitchens, but the way homes draw power from the electrical grid. See omnystudio.com/listener for privacy information....
Feb 29, 2024•35 min•Season 1Ep. 87
Tim Ellis is the co-founder and CEO of Relativity Space, a company with a unique approach to manufacturing rockets. Tim’s problem is this: How can you use 3D printing to make rockets more efficiently? Eventually, Tim wants to send a rocket – and printer – to Mars to build the first Martian industrial base. See omnystudio.com/listener for privacy information.
Feb 22, 2024•36 min•Season 1Ep. 86
Every year in the U.S., tens of thousands of hospital patients die of preventable causes. For many of these patients, warning signs are subtle and easy for doctors to miss. Suchi Saria is the founder and CEO of Bayesian Health, and a professor at Johns Hopkins where she runs a lab focused on machine learning and healthcare. Suchi’s problem is this: How can you use AI to detect when hospital patients are at risk of potentially deadly complications – and how can you get doctors to listen? See omny...
Feb 15, 2024•40 min•Season 1Ep. 85
Gia Schneider is the co-founder and CEO of Natel Energy, a company that is trying to transform the way hydroelectric power works. Gia’s problem is this: how do you draw hydropower from rivers without damaging the ecosystem? As it turns out, we have a lot to learn from nature’s furriest engineers – beavers. See omnystudio.com/listener for privacy information.
Feb 08, 2024•26 min•Season 1Ep. 84
Peter Chen is the co-founder and CEO of Covariant. Peter’s problem is this: How do you take the AI breakthroughs of the past decade or so, and make them work in robots? Peter was one of the first employees at OpenAI, the maker of ChatGPT. On the show, he talks about how AI has evolved, and why it's so difficult to teach a robot to fold a towel. See omnystudio.com/listener for privacy information.
Feb 01, 2024•35 min•Season 1Ep. 83
Fei-Fei Li is a Stanford computer scientist and the former chief scientist of artificial intelligence/machine learning at Google Cloud. When Li entered the field of AI in the 2000s, researchers were making slow progress, optimizing algorithms to incrementally improve outcomes. Li saw that the problem wasn’t the algorithm, but the size of the datasets being used. So she built a massive database of images called ImageNet. It was a huge breakthrough, and helped lead the emergence of modern AI. See ...
Jan 25, 2024•29 min•Season 1Ep. 82
