Episode description

Covid- 19 cases seem to be multiplying daily and there is now a growing body of scientific evidence both on its spread and the effectiveness of measures to try and control it. We look at what’s working, what’s not and why.

And we look to the potential for coronavirus drug treatments, why despite the hype there really isn’t anything round the corner.

Australia’s recent fire season was intense; a new study looks back over 500 years of the weather pattern partly responsible, the Indian Ocean Dipole. The findings show the most extreme years occurred recently – under the influence of man-made climate change.

And we look at life deep below the sea floor, microbes which multiply slowly over centuries and eat their neighbours.

Since the outbreak of a new strain of coronavirus late last year, health workers and governments have been rushing to limit transmission by deploying containment tactics and anti-contamination campaigns. But, as the virus spreads around the world, what are scientists doing to help our bodies fight off or resist this new infectious disease?

Viruses that cause human disease can be notoriously tricky to tackle. They don’t respond to antibiotics, can spread rapidly between human hosts, and even evolve improved ways of working as they multiply. Presenter Marnie Chesterton heads to the University of Oxford’s Nuffield Department of Medicine to meet the researchers who are urgently searching for solutions. Professor Tao Dong is Director of Chinese Academy of Medical Sciences Oxford Institute, collaborating with colleagues on the ground in China to see how Chinese patients’ immune systems are responding to the virus, which could inform vaccine design. Professor Sarah Gilbert leads the Jenner Institute’s influenza vaccine and emerging pathogens programme. She’s been developing a vaccine against another strain of coronavirus that caused the Middle East Respiratory Syndrome (MERS) outbreak, and is using the same technology to generate a new vaccine against the 2019 coronavirus. And, whilst that’s being developed, there is a possibility that some existing antiviral drugs may even help infected patients – Professor Peter Horby is working with colleagues in China on clinical trials to see what might work. CrowdScience goes into the laboratories using cutting edge science to combat coronavirus.

(Image: Coronavirus test. Credit: iStock / Getty Images Plus)