TWiV 860: Evading a Toll on the road to RNA vaccines
Jan 30, 2022•1 hr 49 min•Ep. 860
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Episode description
TWiV reviews a seminal paper showing that chemically modified bases in RNAs suppress recognition by Toll-like receptors, a finding that that was essential for the development of COVID-19 mRNA vaccines.
Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Kathy Spindler
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Links for this episode- Vaccine Town Hall (ASV)
- Columbia University BSL-3 Manager position
- RNA modifications suppress innate recognition (Immunity)
- Critical contribution of pseudouridine (Front Cell Dev Biol)
- Rich Condit reminisces (YouTube)
- Letters read on TWiV 860
- Timestamps by Jolene. Thanks!
Dickson - NASA Research Launches a New Generation of Indoor Farming
Kathy -How Pfizer scientists transformed an old drug lead into a COVID-19 antiviral
Rich - Fermi paradox
Vincent - Racism not Race by Joe Graves
Jay – Restoration of Ave Maria
John – Pandemic humor
Intro music is by Ronald Jenkees
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