TWiV 756: Precluding problematic polio prophylaxis

TWiV returns to the 2012 brouhaha over transmission experiments with avian H5N1 influenza virus, re-examines the claim of SARS-CoV-2 RNA integration into human DNA, and reviews the engineering and testing of a genetically stable version of the attenuated type 2 Sabin poliovirus vaccine.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Amy Rosenfeld

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• ASV vaccine town halls 3:16
• First smallpox vaccine day
• Revised masking and distancing (CDC)
• Science vs Spin (Sandman)
• Artifactual SARS-CoV-2 integration (PNAS)
• SARS-CoV-2 integration is artifactual (J Virol)
• Engineering new OPV2 (Cell Host Micr)
• Safety and immunogenicity of nOPV2 (Lancet)
• Poliopolis (Lancet)
• Letters read on TWiV 756
• Timestamps by Jolene. Thanks!

Dickson – Five Deeps Amy – Premonition by Michael Lewis Alan – The Secret Life of Groceries by Benjamin Lorr Rich – The Way Ferrofluid Floats Above a Superconductor Is Unreal Vincent – Threading the NEIDL

Iradis – SN15 Launch and Landing Blue Pilgrim – Howland Garden Tools

Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv