TWiV 751: Sputnik spat and furin in ferrets

This Week in Virology

May 06, 2021•1 hr 34 min•Ep. 751

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Episode description

TWiV examines the claim by Brazil's ANVISA that the Sputnik vaccine contains replication-competent adenovirus, and a role for the furin cleavage site in SARS-CoV-2 spike for efficient reproduction in the respiratory tract, evasion of antiviral IFITM proteins, and transmission in ferrets.

Hosts: Vincent Racaniello, Rich Condit, and Kathy Spindler

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Links for this episode

ASV vaccine town halls
Brazil rejects Gamaleya vaccine (Sci Transl Med)
Russian vaccine behavior (Sci Transl Med)
Is Gamaleya vaccine safe? (Science)
Furin cleavage site in replication and transmission (Nat Micro)
Furin site loss attenuates pathogenesis (Nature)
Timestamps by Jolene. Thanks!

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Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv

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