TWiV 703: Does dose matter?

On this episode, a discussion of why modifying the dose schedule of the mRNA vaccines in the US is not a good idea, evidence that lower Ct values on hospital admission is associated with higher mortality, and dose-dependent response to SARS-CoV-2 infection of ferrets.

Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Brianne Barker

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• BSL-3 Assistant Manager position
• Follow authorized vaccine dosing schedule (FDA)
• Mina suggests one vaccine dose (NY Times)
• UK decision document on vaccine dose (pdf)
• Ct linked to COVID-19 mortality (Open Forum Inf Dis)
• Dose-dependent infection of ferrets (Nat Comm)
• Letters read on TWiV 703
• Timestamps by Jolene. Thanks!

Brianne – Linsey Marr on masks Kathy – Striped Martian Sand Dunes and Rich – How Microwaving Grapes Makes Plasma Vincent – Musings of an anonymous, pissed off virologist

Laura – Auld Lang Syne follow-up

Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv