TWiV 1104: Clinical update with Dr. Daniel Griffin
Episode description
In his weekly clinical update, Dr. Griffin reviews recent statistics on the circulation of measles before addressing results of Pfizer's phase 3 RSV vaccine clinical trial for adults under 60, RSV, influenza and SARS-CoV-2 circulation, differences between rural and urban communities dealing with SARS-CoV-2 infections, the latest statistics on influenza and COVID-19 circulation, restates the guidelines for spring administration of COVID vaccines boosters, discusses the emergency use application of a pre-exposure prophylactic. revised guidelines for how to treat respiratory viral infection guidelines by the CDC, continues to dispel the myth of viral rebound, revised guidelines SARS-CoV-2 treatment and how to treat respiratory viral infections, when to use steroids and the benefits of convalescent plasma, what do when healthcare workers succumb to SARS-CoV-2 infection, how long COVID affects the brain and associates with an increase in allergic incidents as well as if post SARS-CoV-2 infected patients are unable to exercise or have functional limitations. For more information about this body of work, listen to TWiV 1088.
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Links for this episode- Measles tracking (CDC)
- Measles just this year (MMWR)
- ABRYSVO phase 3 results (Pfizer)
- RSV surveillance (CDC)
- Influenza/flu surveillance (CDC)
- Provisional deaths due to COVID-19 (CDC)
- COVID-19 national trend (CDC)
- COVID-19 wastewater testing (biobot)
- Variant tracker (CDC)
- Rural-urban differences in COVID-19 mortality and hospitalizations (OFID)
- Spring COVID-19 booster recommendations (CIDRAP)
- Older adult spring booster available (CDC)
- Advisory committee for immunization practices spring 2024 COVID-19 boosters (CDC)
- EUA for pemgarda (FDA)
- CDC Quarantine guidelines (CDC)
- NIH COVID-19 treatment guidelines (NIH)
- Nirmatrelvir for vaccinated or unvaccinated COVID-19 patients (NEJM)
- Assessment for clinical usefulness (NEJM)
- Molnupiravir safety and efficacy (JMV)
- Convalescent plasma recommendation for immunocompromised (IDSociety)
- Updated respiratory virus guidances (CDC)
- What do when your heathcare provider is infected with SARS-CoV-2 (CDC)
- Managing healthcare staffing shortages (CDC)
- Steroids,dexamethasone at the right time (OFID)
- Anticoagulation guidelines (hematology.org)
- Long COVID evidence based review TWiV shout out (TWiV 1088)
- Brian and cognitive changes in long COVID patients (BRAIN)
- Allergic disease incidents after COVID-19 (Nat Comm)
- Can post COVID patients exercise or do they have functional limitations (JAMA Network Open)
- Contribute to our ASTMH fundraiser at PWB 37:06
- Letters read on TWiV 1102 37:56
- Dr. Griffin's COVID treatment summary (pdf)
- Timestamps by Jolene. Thanks!
Intro music is by Ronald Jenkees
Send your questions for Dr. Griffin to daniel@microbe.tv