This Week in Virology - podcast cover

This Week in Virology

Vincent Racaniellowww.microbe.tv
TWiV is a weekly netcast about viruses - the kind that make you sick. Brought to you by four university professors and a science writer.
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Episodes

TWiV 1240: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin with Vincent Racaniello chat about the recent Salmonella typhimurim outbreak, the ousting of another CBER director, confirmation of a new CDC director and results of a recent pool about vaccine safety and trust before Dr. Griffin deep dives into recent statistics on RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, a new anti-influenza antibody that can be combined with neuraminidase inhibitors, whether or not the NB.1.8.1 should...

Aug 02, 202548 minEp. 1240

TWiV 1239: Aluminum and antibodies

TWiV explains a cohort study of over one million Danish children which shows no evidence supporting an increased risk for autoimmune, atopic or allergic, or neurodevelopmental disorders associated with early childhood exposure to vaccines with aluminum-base adjuvants, and a study of antibodies induced by mRNA-1273 and NVX-CoV2373 COVID-19 vaccines which show that polyclonal antibodies against a single site on the spike N-terminal domain show immunodominance, high diversity, and limited cross-rea...

Jul 27, 20251 hr 51 minEp. 1239

TWiV 1238: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin with Vincent Racaniello chat about how flies and milk-snatching might contribute to influenza virus H5N1 among dairy cattle, the recent pertussis oubreak and measles epidemic before Dr. Griffin discusses monoclonal antibody therapy can enrich for RSV variants before deep diving into recent statistics on RSV, influenza and SARS-CoV-2 infections the Wasterwater Scan dashboard, whether or not the NB.1.8.1 should be included in the fall 2025 vaccines, the e...

Jul 26, 202545 minEp. 1238

TWiV 1237: Hepatitis C and persistence with Charlie Rice

From the 2025 annual meeting of the American Society for Virology, Charlie Rice, 2020 Nobel Laureate in Physiology or Medicine, talks with Vincent and Kathy about his career and the scientific difficulties he and his laboratory encountered in their attempts to achieve replication of hepatitis C virus in cells in culture. Hosts: Vincent Racaniello and Kathy Spindler Guest: Charlie Rice Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Support science e...

Jul 20, 20251 hr 6 minEp. 1237

TWiV 1236: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin with Vincent Racaniello have a morning chat about the measles epidemic and H5N1 in cows before Dr. Griffin discusses how vaccination associates with reduced dementia risk before deep diving into recent statistics on measles epidemic, RSV, influenza and SARS-CoV-2 infections the Wasterwater Scan dashboard, a potential new influenza antiviral drug, whether or not the NB.1.8.1 variant should be included in the fall 2025 vaccines, immunization recommendatio...

Jul 19, 202549 minEp. 1236

TWiV 1235: Two sexy to eradicate

David Barton, Brian Kemp, and Olve Peersen join TWiV to discuss RNA recombination among enteroviruses and its role in foiling poliovirus eradication. Hosts: Vincent Racaniello , Alan Dove , and Rich Condit Guests: David Barton , Brian Kempf , and Olve Peersen Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Enterovirus C recombination groups (J Virol) Poliovirus polymerase L420 facilitates RNA recombination (J V...

Jul 13, 20251 hr 36 minEp. 1235

TWiV 1234: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin with Vincent Racaniello note that history is being rewritten for justification of changes in COVID vaccine guidelines including myocarditis incidence and the Great Barrington Declaration ignoring presentations at the April 2025 ACIP, the response by the medical community to these changed guidelines, before Dr. Griffin discusses how vaccination associates with reduced dementia risk before deep diving into recent statistics on measles epidemic, RSV, influ...

Jul 12, 202555 minEp. 1234

TWiV 1233: Long COVID and big bats

TWiV covers FDA Director overriding scientists on COVID shots, NIH funded science must now be free to read instantly, Trump cuts subscriptions to Springer Nature journals, UK and Gates make up for US money withdrawn from GAVI, US defunding USAID could lead to 14 million deaths by 2030, then reviews research on how host IL1 genetics regulates Epstein-Barr virus reactivation and long COVID, and enhanced antiviral capacity of bat innate immunity. Hosts: Vincent Racaniello , Alan Dove , and Rich Con...

Jul 06, 20251 hr 51 minEp. 1233

TWiV 1232: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin with Vincent Racaniello are shocked at how vaccine safety is undercut by misrepresenting thimerosal safety, its removal from vaccines, and how CBER director Vinay Prasad overruled his advisors for the administration of COVID vaccines to pregnant people knowingly compromising their health, before Dr. Griffin reviews recent statistics on measles epidemic, RSV, influenza and SARS-CoV-2 infections the Wasterwater Scan dashboard, whether or not the NB.1.8.1 ...

Jul 05, 202557 minEp. 1232

TWiV 1231: What is a virus?

TWiV discusses Sen. Cassidy calling for ACIP meeting delay, RFK Jr. abandons GAVI, millions of children at risk as global vaccination rates fall, RFK Jr. grilled by Congress, autism rates have increased 60-fold due to changed definitions, deep mutational scanning of rabies virus glyoprotein, and and proton gradient and incomplete TCA cycle in a giant virus. Hosts: Vincent Racaniello , Rich Condit , Brianne Barker , and Angela Mingarelli Subscribe (free): Apple Podcasts , RSS , email Become a pat...

Jun 29, 20251 hr 55 minEp. 1231

TWiV 1230: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin with Vincent Racaniello are alarmed at how RFK is breaking his promise of not altering vaccine policies, and nonexistent data and studies are used by members of the ACIP to make changes to immunization practices in the absence of a CDC director, justification for not honoring the US commitment to GAVI and global public policies including support of routine childhood immunizations, placing millions of children at risk for the return of vaccine preventabl...

Jun 28, 202549 minEp. 1230

TWiV 1229: Virology throughout Europe

Rich travels to Dubrovnik for the European Congress of Virology 2025 and Vincent joins via Zoom to speak with Stéphane Blanc, Vanda Juranić Lisnić, and Elisabeth Puchhammer-Stöckl about their work on plant viruses, cytomegalovirus, and Epstein-Barr virus. Hosts: Vincent Racaniello and Rich Condit Guests: Stéphane Blanc , Vanda Juranić Lisnić , and Elisabeth Puchhammer-Stöckl Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Support science education a...

Jun 22, 20251 hr 23 minEp. 1229

TWiV 1228: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin and Vincent Racaniello discuss in shock how RFK is breaking his promise of not altering vaccine policies by appointing new members of the ACIP, next ACIP meeting on guidelines for the COVID and RSV vaccines, circulation of "human insect viruses" including West Nile virus, and an outbreak of mpox on a cruise ship, and the ongoing measles outbreak before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections the Wasterwater Scan...

Jun 21, 202545 minEp. 1228

TWiV Special: Long COVID and ME/CFS with David Tuller

David Tuller returns to TWiV to discuss RFK Jr. and the trashing of American public health, rituximab and ME/CFS, The Sick Times, the Cochrane Mess, a Norwegian Long Covid trial, effort preference and more. Host: Vincent Racaniello Guest: David Tuller Subscribe (free): Apple Podcasts , Google Podcasts , RSS , email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server David Tuller writes at virology blog CFS, a long tangled tale (virology blog) The Sick Times Norwegian Long CO...

Jun 17, 20251 hr 2 min

TWiV 1227: How can antibody forget a pandemic?

TWiV reviews the administrations dismantling of the committee that studies pandemic potential, firing of CDC vaccine advisory committee and replacing them with unqualified anti-vaxxers, zoonotic and sustained Mpox spread in Nigeria and Cameroon, and breadth of influenza A antibody cross-reactivity. Hosts: Vincent Racaniello , Alan Dove , and Brianne Barker Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV 2:39 NI...

Jun 15, 20251 hr 50 minEp. 1227

TWiV 1226: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin with Vincent Racaniello in horror examine dismantling of public infrastructure for establishing vaccine guidelines, the creation of a autism taskforce by someone disciplined for practicing medicine without a license, the ongoing pertussis, bird flu and measles outbreaks, before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections the Wasterwater Scan dashboard, the effective of oseltamivir vs supportive care when one is hosp...

Jun 14, 202530 minEp. 1226

TWiV 1225: Poultry flu and SARS-CoV-2

TWiV reviews the administration's call for fools gold-standard science, NIH may publish in-house, avian influenza viruses in birds in China, and Omicron pathogenicity and immune responses. Hosts: Vincent Racaniello , Alan Dove , Rich Condit , and Kathy Spindler Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Fool's Gold Standard Science (Nature) NIH may publish in-house (Stat News) Diversity of H9N2 in China (N...

Jun 08, 20251 hr 57 minEp. 1225

TWiV 1224: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin with Vincent Racaniello in dismay examine the MAHA-Make America Health Again-report and its inclusion of fictious studies or "Creative literature degree Medical Science writing", RFK Jr contradicted by the CDC for COVID-19 vaccine recommendations for children, reduction in MMR vaccine coverage, the ongoing bird flu and measles outbreaks, how the General Accounting Office instructed HHS to fix deficiencies in infectious disease testing before the next pa...

Jun 07, 202556 minEp. 1224

TWiV 1223: Someone is guano be sick

TWiV reviews RFK Jr."s MAGA report with non-existent literature citations, a new fungus that could further devastate North American bats, surveillance of avian influenza viruses through bird guano in remote regions, and the receptor for HKU5 coronaviruses is ACE2 from Pipistrellus abramus bats. Hosts: Vincent Racaniello , Kathy Spindler , and Brianne Barker Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Bad ci...

Jun 01, 20251 hr 51 minEp. 1123

TWiV 1222: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin with Vincent Racaniello discusses vaccination trends, the changes COVID-19 vaccine recommendations for children and pregnant women, easing of vaccination exemptions in Texas, the ongoing measles outbreak globally before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections the Wasterwater Scan dashboard, whether or not the NB.1.8.1 should be included in the fall 2025 vaccines and concern as confirmed diagnosis of COVID-19 ris...

May 31, 20251 hr 5 minEp. 1222

TWiV 1221: Nonsense mediated decay

TWiV reviews cuts in National Science Foundation budgets, cuts to Harvard University grants, judge blocks ban on Harvard enrolling international students, DOGE ordered cuts of NIH grants, endemic coronavirus infection induces Fc receptor binding antibodies to SARS-CoV-2, and inherited IFNAR1 deficiency causing adverse reactions to measles and yellow fever infectious vaccines. Hosts: Vincent Racaniello , Alan Dove , and Angela Mingarelli Subscribe (free): Apple Podcasts , RSS , email Become a pat...

May 25, 20251 hr 59 minEp. 1221

TWiV 1220: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin with Vincent Racaniello debate the changes in FDA vaccine approval policy especially how it is applied to COVID-19 vaccines and restricts vaccine availability/usage and Novavax's vaccine, mpox on surfaces and in the air, "bird flu", the ongoing measles outbreak globally before Dr. Griffin reviews recent statistics on RSV, benefits of vaccination for infants, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, the high number of childhoo...

May 24, 202554 minEp. 1220

TWiV 1219: Koalas sweep horse shift

TWiV reviews pause in the use of Chikungunya vaccine, HHS to stop recommending COVID shots for pregnant women and children, molecular basis for shifted receptor recognition by an encephalitic alphavirus, and evolution of koala retrovirus transcriptional silencing in wild koalas. Hosts: Vincent Racaniello , and Rich Condit Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Pause in use of Ixchiq (FDA) Change in COV...

May 18, 20251 hr 55 minEp. 1219

TWiV 1218: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin with Vincent Racaniello wail about the attack on science within the US, cancellation of CDC's committee on infectious diseases, mpox in Sierra Leone, "bird flu" in cats, the ongoing measles outbreak globally, before Dr. Griffin reviews recent statistics on RSV, benefits of vaccination for infants, influenza and SARS-CoV-2 infections the WasterwaterScan dashboard, the high number of childhood deaths during this "flu" season, the May 22 VRBPAC COVID-19 va...

May 17, 20251 hr 2 min

TWiV 1217: Alternative vax and pandemic origins

TWiV reviews new CBER chief at FDA, ending of Gates Foundation in 2045, gain of function executive order, origins of bat viruses ancestral to SARS-CoV and SARS-CoV-2, and single dose Sudan virus replicon vaccine protects guinea pigs from disease. Hosts: Vincent Racaniello , Alan Dove , and Rich Condit Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Prasad replaces Marks at FDA (US News) Gates Foundation ends 20...

May 11, 20251 hr 53 minEp. 1217

TWiV 1216: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin with Vincent Racaniello bemoan the attack on science within the US, salt water controls for vaccines, return to 1938 technology for flu vaccines, mRNA vaccines as "bioweapons", rise in pertussis, benefits of the shingles vaccine and reduced dementia occurrence, and growing measles outbreak globally before Dr. Griffin reviews recent statistics on RSV, influenza and SARS-CoV-2 infections, the WasterwaterScan dashboard, the May 22 VRBPAC COVID-19 vaccine, ...

May 10, 202550 minEp. 1216

TWiV Special: A shot of HepB with Thomas Tu

From the 2024 International Hepatitis B virus meeting in Chicago IL, Rich Condit speaks with Thomas Tu about his experiences as a both a HepB scientist and patient. Host: Rich Condit Guest: Thomas Tu Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Hepatitis B Foundation Tu Laboratory Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.t...

May 06, 202525 min

TWiV 1215: What's the worst that could happen?

TWiV reviews universal vaccine initiative at NIAID, shut down of the Integrated Research Facility at Ft. Detrick, modeling the reemergence of infectious diseases as vaccination rates drop, and bacterial outer membrane vesicles bound to bacteriophages modulate neutrophil responses to bacterial infection. Hosts: Vincent Racaniello , Alan Dove , and Jolene Ramsey Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV ASV...

May 04, 20252 hr 2 minEp. 1215

TWiV 1214: Clinical update with Dr. Daniel Griffin

In his weekly clinical update, Dr. Griffin with Vincent Racaniello bewail the attack on science within the US and withdrawal from the global health communities, association between the shingles vaccine and reduced dementia occurrence, ending of Uganda's ebola outbreak, undermining effective responses to human bird flu infections, growing measles outbreak in the US and dire predictions of the return of vaccine preventable diseases including polio if vaccination rates continue to decline, before D...

May 03, 202549 minEp. 1214

TWiV Special: A shot of HepB with Chari Cohen

From the 2024 International Hepatitis B virus meeting in Chicago IL, Rich Condit speaks with Chari Cohen about her work as President of the Hepatitis B Foundation. Host: Rich Condit Guest: Chari Cohen Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV Hepatitis B Foundation Timestamps by Jolene Ramsey. Thanks! Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in ...

Apr 29, 202523 min
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