In his weekly clinical update, Dr. Griffin delves highly pathogenic H5N1 biology including its circulation in New York City, being able to infect cells within mammary glands and why testing is not supported before reviewing the recent statistics on SARS-CoV-2 infection, how vaccination reduced deaths and hospitalizations associated with COVID-19 and how to take off PPE to reduce virus transmission, discussing the guidelines for spring administration of COVID vaccines boosters, the emergency use ...
May 25, 2024•47 min•Ep. 1116
TWiV reviews results of a phase 3 trial of a self-amplifying mRNA COVID-19 vaccine, and the finding that baseline innate and T cell populations are correlates of protection against symptomatic influenza virus infection independent of serology. Hosts: Dickson Despommier , Alan Dove and Brianne Barker Subscribe (free): Apple Podcasts , Google Podcasts , RSS , email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Michelson Prizes: Next Generatio...
May 19, 2024•1 hr 40 min•Ep. 1115
In his weekly clinical update, Dr. Griffin delves into discussing drinking “raw” milk possessing H5N1 influenza virus, if the virus can reproduce in the human gut, and the meaning of finding viral RNA in wastewater samples before reviewing the recent statistics on SARS-CoV-2 infection, the guidelines for spring administration of COVID vaccines boosters, withdrawal of AstraZeneca’s SARS-CoV-2 vaccine from the European market, discusses the emergency use application of a pre-exposure prophylactic,...
May 18, 2024•48 min•Ep. 1114
Richard Webby joins TWiV to review the history of avian H5N1 influenza virus, the recent change in epidemiological patterns, infection of dairy cattle in the US, and the risk of an outbreak in humans. Hosts: Vincent Racaniello , Alan Dove, and Brianne Barker Guest: Richard Webby Subscribe (free): Apple Podcasts , Google Podcasts , RSS , email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Webby research laboratory H5N1 virus in dairy cattle ...
May 12, 2024•1 hr 21 min•Ep. 1113
In his weekly clinical update, Dr. Griffin deep dives into infections of dairy cattle with high pathogenic influenza H5N1, how long virus has been circulating and if known anti-influenza antivirals can reduce secondary attack rates, before reviewing the recent statistics on SARS-CoV-2 infection, the guidelines for spring administration of COVID vaccines boosters, whether COVID booster takes associates with long COVID prevalence, discusses the emergency use application of a pre-exposure prophylac...
May 11, 2024•47 min•Ep. 1112
TWiV reviews viruses in the news: Chinese scientist who released the SARS-CoV-2 genome sequence sleeps in the street, a case of measles in Haifa, spread of waterborne infectious diseases in Gaza, interstate spread of avian influenza A(H5N1) in dairy cattle, and an orangutan heals himself with medicinal plants, followed by identification of a cell receptor for parechoviruses, and blockade of necroptosis prevents lung injury in severe influenza. Hosts: Vincent Racaniello , Dickson Despommier , and...
May 05, 2024•1 hr 40 min•Ep. 1111
In his weekly clinical update, Dr. Griffin begins with discussing if the antibiotic neomycin is really a pan-antiviral countermeasure, then reviews the recent statistics on SARS-CoV-2 infection before deep diving into if shedding and the rapid antigen test results correlate, the guidelines for spring administration of COVID vaccines boosters, whether COVID booster associates with the long COVID prevalence, discusses the emergency use application of a pre-exposure prophylactic, revised guidelines...
May 04, 2024•52 min•Ep. 1110
TWiV reviews avian H5N1 influenza virus in the US, measles at highest levels in England, positive selection underlies repeated knockout of ORF8 in SARS-CoV-2 evolution, and cross-species spill-over potential of the H9N2 bat influenza A virus. Hosts: Vincent Racaniello , Dickson Despommier , and Alan Dove Subscribe (free): Apple Podcasts , Google Podcasts , RSS , email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Become a member of ASV ( as...
Apr 28, 2024•1 hr 39 min•Ep. 1109
In his weekly clinical update, Dr. Griffin reviews recent statistics on the circulation of measles, and H51 influenza infection of birds, poultry and cows before and SARS-CoV-2 circulation, before discussing if the original monovalent SARS-CoV-2 vaccine was effective in children and adolescents, how to use words to properly describe respiratory pathogens the guidelines for spring administration of COVID vaccines boosters, discusses the emergency use application of a pre-exposure prophylactic, re...
Apr 27, 2024•43 min•Ep. 1108
It has been a long time since TWiV has released an all listener email episode, and if you have been waiting for one, then this episode is for you! (and everyone else of course). Hosts: Vincent Racaniello , Alan Dove , and Brianne Barker Subscribe (free): Apple Podcasts , Google Podcasts , RSS , email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Become a member of ASV ( asv.org ) The New City by Dickson Despommier ( blog post ) Internationa...
Apr 21, 2024•1 hr 52 min•Ep. 1107
In his weekly clinical update, Dr. Griffin reviews recent statistics on the circulation of measles, potential risk factors for severe disease following influenza infection before and SARS-CoV-2 circulation, before discussing if SARS-CoV-2 infection impacts sperm fertility, the guidelines for spring administration of COVID vaccines boosters, discusses the emergency use application of a pre-exposure prophylactic. revised guidelines for how to treat respiratory viral infection guidelines by the CDC...
Apr 20, 2024•44 min•Ep. 1106
TWiV reviews influenza H5N1 in North American cows and in birds throughout New York City, polio health emergency extended, ChatGPT to control vaccine hesitancy, increasing viral hepatitis worldwide, dengue public health alert in Puerto Rico, cherry trees drowning in Washington DC, death of iron lung Paul, origin and dispersal history of hepatitis B virus in Eastern Eurasia, and antibody-independent protection against heterologous SARS-CoV-2 challenge. Hosts: Vincent Racaniello , Alan Dove , Rich...
Apr 14, 2024•1 hr 58 min•Ep. 1105
In his weekly clinical update, Dr. Griffin reviews recent statistics on the circulation of measles before addressing results of Pfizer’s phase 3 RSV vaccine clinical trial for adults under 60, RSV, influenza and SARS-CoV-2 circulation, differences between rural and urban communities dealing with SARS-CoV-2 infections, the latest statistics on influenza and COVID-19 circulation, restates the guidelines for spring administration of COVID vaccines boosters, discusses the emergency use application o...
Apr 13, 2024•47 min•Ep. 1104
Vincent travels to the University of Texas in Austin to speak with speak with Jason McLellan about his career and his research on the SARS-CoV-2 spike protein, including the effect of adding two proline residues, its effect on other viral spike glycoproteins, and general approaches to vaccine design. Hosts: Vincent Racaniello and Rich Condit Guest: Jason McLellan Subscribe (free): Apple Podcasts , Google Podcasts , RSS , email Become a patron of TWiV! Links for this episode MicrobeTV Discord Ser...
Apr 07, 2024•1 hr 5 min•Ep. 1103
In his weekly clinical update, Dr. Griffin reviews recent statistics on the circulation of measles and influenza before addressing Vincent’s comment on measles inclusion in the clinical respiratory PCR panel, the latest statistics on influenza and COVID-19 circulation, if inflammatory cytokines and anti-viral antibody function synergistically, if administration of peptide agonists of the glucagon-like or sodium-glucose pump can reduce disease severity, restates the guidelines for spring administ...
Apr 06, 2024•50 min•Ep. 1102
Paul Offit joins TWiV to discuss his latest book, “Tell Me When It’s Over”, an insider’s guide to deciphering COVID myths and navigating our post-pandemic world. Hosts: Vincent Racaniello , Dickson Despommier , and Brianne Barker Guest: Paul Offit Subscribe (free): Apple Podcasts , Google Podcasts , RSS , email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Become a member of ASV ( asv.org ) The New City by Dickson Despommier Tell Me When It...
Mar 31, 2024•1 hr 50 min•Ep. 1101
In his weekly clinical update, Dr. Griffin reviews recent statistics on the circulation of measles influenza and SARS-CoV-2, before discussing the development of new monoclonal antibody therapy, if vaccines and antivial drugs can used effectively together. revised guidelines for how to treat respiratory viral infection guidelines by the CDC, continues to dispel the myth of viral rebound including that after administration of the “oral remdesivir”, revised guidelines SARS-CoV-2 treatment and how ...
Mar 30, 2024•44 min•Ep. 1100
Vincent travels to the University of Heidelberg to speak with Volker Lohmann about his career and the research of his laboratory on hepatitis C virus, hepatitis A virus, and norovirus. Host: Vincent Racaniello Guests: Volker Lohmann Subscribe (free): Apple Podcasts , Google Podcasts , RSS , email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Become a member of ASV ( asv.org ) The New City by Dickson Despommier HCV human challenge studies (L...
Mar 24, 2024•1 hr 13 min•Ep. 1099
In his weekly clinical update, Dr. Griffin deep dives into recent domestic and global measles and mpox outbreaks, before reviewing recent statistics on the circulation of respiratory syncytial virus, influenza and SARS-CoV-2, discussing revised guidelines for how to treat respiratory viral infection guidelines by the CDC, revised guidelines SARS-CoV-2 treatment and how to treat respiratory viral infections, continues to dispel the myth of viral rebound, when to use steroids and the benefits of c...
Mar 23, 2024•49 min•Ep. 1098
Vincent travels to the fifth Giant Virus Meeting in Tegernsee, Germany and speaks with Sheree Yau and Victoria Queiroz about their research on picoeukaryotes (tiny algal cells) and their viruses, pithoviruses, and an educational kit for virology classes. Host: Vincent Racaniello Guests: Sheree Yau and Victoria Queiroz Subscribe (free): Apple Podcasts , Google Podcasts , RSS , email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Become a memb...
Mar 17, 2024•57 min•Ep. 1097
In his weekly clinical update, Dr. Griffin highlights measles outbreaks throughout the continental US, reviews recent statistics on the circulation of respiratory syncytial virus, influenza and SARS-CoV-2 before discussing if vaccination protected children from the development of long COVID or cardiovascular diseases associated with virus infection, revised guidelines SARS-CoV-2 treatment and how to treat respiratory viral infections, continues to dispel the myth of viral rebound, when to use st...
Mar 16, 2024•41 min•Ep. 1096
TWiV reviews heterosexual transmission of clade I Mpox virus, continued circulation of oropouche virus in South America, herpesviruses in South American fur seals and sea lions, sex-specific differences in physiological responses to SARS-CoV-2 infection, underdetected dispersal and extensive local transmission drove the 2022 mpox epidemic, and a humanized mouse model for adenovirus-associated virus gene therapy. Hosts: Vincent Racaniello , Dickson Despommier , Alan Dove , Rich Condit , and Angel...
Mar 10, 2024•1 hr 46 min•Ep. 1095
In his weekly clinical update, Dr. Griffin reviews recent statistics on the circulation of respiratory syncytial virus, influenza and SARS-CoV-2 before discussing revised guidelines for how to treat respiratory viral infection guidelines by the CDC, effectiveness of the new SARS-CoV-2 vaccines and the combination of vaccination and antiviral therapy against the development of disease, continues to dispel the myth of viral rebound, how to pay for paxlovid, the lack of evidence supporting ivermect...
Mar 09, 2024•53 min•Ep. 1094
TWiV discusses effectiveness of this season’s flu vaccine, efficacy of Pfizer RSV vaccine, nOPV2 in the US, dengue in Peru, measles in Michigan and Indiana, how coordinated inflammatory responses dictate control of Marburg virus by reservoir bats, and tRNA acquisition in phages driven by degradation of host translational machinery. Hosts: Vincent Racaniello , Rich Condit , Kathy Spindler , Brianne Barker, and Jolene Ramsey Subscribe (free): Apple Podcasts , Google Podcasts , RSS , email Become a...
Mar 03, 2024•1 hr 56 min•Ep. 1093
In his weekly clinical update, Dr. Griffin reviews recent statistics on the circulation of respiratory syncytial virus, influenza and SARS-CoV-2 before discussing new vaccine guidelines released by the advisory committee on immunization practices, and reviews the CDC guidelines for quarantine/ isolation following SARS-CoV-2 infection, continues to dispel the myth of viral rebound, how to pay for paxlovid, when to use steroids and the benefits of convalescent plasma, the role of IFN-g in long COV...
Mar 02, 2024•56 min•Ep. 1092
TWiV reviews resurgence of Lassa fever in West Africa, at least 3 paralytic cases of cVDPV2 in Zimbabwe, CWD from eating prion-laden plants, measles in New Orleans and Broward County Florida, failure of Florida Surgeon General to support vaccination, a measles variant in Switzerland, SARS-CoV-2 persistent infections, leaky blood-brain-barrier for long COVID brain fog, West Nile virus transmitted among mosquitoes by the excreta, and viroid-like colonists of human microbiomes. Hosts: Vincent Racan...
Feb 25, 2024•1 hr 49 min•Ep. 1091
In his weekly clinical update, Dr. Griffin reviews recent statistics on the circulation of respiratory syncytial virus before discussing uptake of the RSV vaccine Abrysvo or the monoclonal anti-RSV antibody nirsevimab to prevent severe disease following RSV infection in infants 8 months or younger before going over this week’s influenza virus and SARS-CoV-2 virus statistics, including all circulating variants in the US, examines if self-testing is more accurate than clinician administered Binax ...
Feb 24, 2024•36 min•Ep. 1090
TWiV reviews a fatal Alaskapox case, MERS in Kenya, diagnostic tests for Nipah and Lassa diseases, HPV vaccination rates in the US, cases of measles in Arizona and Minnesota, hepatitis C virus-derived RNA circles in infected cells, and prevention of respiratory virus transmission by resident memory CD8+ T cells. Hosts: Vincent Racaniello , Dickson Despommier , Alan Dove , and Brianne Barker Subscribe (free): Apple Podcasts , Google Podcasts , RSS , email Become a patron of TWiV! Links for this e...
Feb 18, 2024•1 hr 50 min•Ep. 1089
In his weekly clinical update, Dr. Griffin discusses the use of monoclonal antibody therapy to prevent RSV hospitalization of infants and use of GSK’s RSV vaccine Arexy to prevent severe disease following RSV infection in adults between 50-59 years before he reviews recent statistics on the circulation of respiratory syncytial virus, influenza virus and SARS-CoV-2 virus, including all circulating variants in the US, discusses if how the influenza vaccine is manufactured can reprogram the antibod...
Feb 17, 2024•59 min•Ep. 1088
TWiV reviews rhinovirus complications in infants, a new influenza antiviral drug, Oropouche fever in Brazil, measles in Maryland and Ohio, effect of eliminating non-medical vaccine exemptions in NY, foot-and-mouth disease in Europe, severe primary and secondary dengue infections, and therapeutic mitigation of measles-like immune amnesia and exacerbated disease after prior respiratory virus infections. Hosts: Vincent Racaniello , Dickson Despommier , Rich Condit , and Angela Mingarelli Subscribe ...
Feb 11, 2024•1 hr 52 min•Ep. 1087
