TWiV reviews the appearance of poliovirus in Europe, mystery disease in DRC, global burden of Chikungunya, viruses of parasitic nematodes that induce antibody responses in vertebrate hosts, and picobirnaviruses, do they infect eukaryotes or prokaryotes? Hosts: Vincent Racaniello , Alan Dove , and Jolene Ramsey Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode ASV 2025 Write your senators about RFK Jr Support science education at MicrobeTV Poliovirus i...
Dec 15, 2024•2 hr•Ep. 1175
In his weekly clinical update, Dr. Griffin deep dives into whether the mysterious respiratory illness in the Congo is malaria, and in conjunction with your host Vincent Racaniello discusses the failure of the poliovirus eradication campaign with virus circulation detected throughout Europe and how we should focus on disease control not virus circulation, then returns to discussing avian influenza in raw milk and the early stoppage of the mpox antiviral Tecovirimat before reviewing the recent sta...
Dec 14, 2024•49 min•Ep. 1174
TWiV reviews nominees to head NIH, FDA, and CDC, cervical cancer decline following HPV vaccination, local dengue in Texas, human isolate of H5N1 virus is transmissible and virulent in animal models, and shared mechanisms of immune evasion among animal and bacterial viruses. Hosts: Vincent Racaniello , Alan Dove , Rich Condit , Kathy Spindler , Brianne Barker , and Jolene Ramsey Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Bhattacharya nominated t...
Dec 08, 2024•2 hr•Ep. 1173
In his weekly clinical update, Dr. Griffin summarizes influenza and RSV circulation in the US, the benefit of administering oseltamivir early and if influenza vaccination reduces secondary household infections, before reviewing the recent statistics on SARS-CoV-2 infection, the WasterwaterScan dashboard, how 1st or 2nd trimester SARS-CoV-2 infections may shorten newborn telomeres, what are B1 cells, if IgG4 responses are critical for protection elicited by mRNA vaccines, if there is a difference...
Dec 07, 2024•38 min•Ep. 1172
TWiV reviews susceptibility to vaccine-preventable infections in asylum seekers, the economic power of vaccines, French university tries to bury its investigation of a faculty member’s ethical lapses, transmission dynamics of SARS-CoV-2 in New Zealand before and after COVID-19, and a germ line encoded antibody that recognizes a broad array of enveloped viruses. Hosts: Vincent Racaniello , Alan Dove , Rich Condit , and Brianne Barker Subscribe (free): Apple Podcasts , RSS , email Become a patron ...
Dec 01, 2024•1 hr 41 min•Ep. 1171
In his weekly clinical update, Dr. Griffin dives into H5N1/influenza and RSV circulation in the US, whether or not H5N1 is “adapting” for human-human transmission, why drinking raw milk may NOT be the best idea despite RFK Jr endorsement, before reviewing the recent statistics on SARS-CoV-2 infection, the WasterwaterScan dashboard, how if I encounter no one I can infect no one, the efficacy of COVID-19 boosters, how vaccines are the ‘seat belt’ of public health, the results of two PLACEBO contro...
Nov 30, 2024•54 min•Ep. 1170
TWiV travels to Brisbane, Australia for the Options XII for the control of influenza conference, and meets up with Stephanie Gras and Jenna Guthmiller to talk about their careers and their research. Hosts: Vincent Racaniello , Kathy Spindler , and Steph Langel Guests: Stephanie Gras and Jenna Guthmiller Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode Goldilocks zone of influenza immunity (J Inf Dis) Broadly neutralizing HA antibodies (Nature) T cell...
Nov 24, 2024•54 min•Ep. 1169
In his weekly clinical update, Dr. Griffin briefly discusses the E.coli outbreak associated with onions from McDonald’s before deep diving into the announcement of Robert F Kennedy Jr. nomination for Secretary of Human and Health Services with highlights from MicrobeTV ’s own Vincent Racaniello and Paul Offit ( Beyond the Noise ), the global measles outbreak, underutilization of influenza antivirals for children and teens, the $350 million 2025 order for mpox vaccination, before reviewing the re...
Nov 23, 2024•1 hr 3 min•Ep. 1168
TWiV reveals a novel H5N1 reassortant virus in Cambodia, circulating vaccine derived poliovirus type 2 in more countries, circulation in the blood of humans of infectious parvovirus B19 coated with active proteases, and B cell receptor dependent enhancement of dengue virus infection. Hosts: Vincent Racaniello , Dickson Despommier , Kathy Spindler , and Brianne Barker Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV ...
Nov 17, 2024•1 hr 43 min•Ep. 1167
In his weekly clinical update, Dr. Griffin apprises us about the first case of highly pathogenic influenza in Canda, children dying of influenza infection and novel genetic reassortments of the virus, the Marburg virus outbreak in Rwanda, number of mpox infections, before reviewing the recent statistics on SARS-CoV-2 infection, the WasterwaterScan dashboard, how scientific mistrust has affected COVID-19 vaccine administration, resolution of the FDA hold on Novovax’s combination influenza and COV...
Nov 16, 2024•46 min•Ep. 1166
TWiV notes the passing of virologist Diane Griffin, first H5N1 influenza virus in US pigs, Innate immune control of influenza virus interspecies adaptation via IFITM3, and antiviral trained innate immunity in alveolar macrophages after SARS-CoV-2 infection reduces secondary influenza A virus disease. Hosts: Vincent Racaniello , Alan Dove , Rich Condit , Kathy Spindler , and Brianne Barker Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode MicrobeTV Dis...
Nov 10, 2024•1 hr 45 min•Ep. 116
In his weekly clinical update, Dr. Griffin informs us about the World Health Organization research and development plan to combat endemic pathogens including hepatitis C virus, RSV and dengue virus, another case of mpox in Britian, the Marburg virus outbreak in Rwanda, before reviewing the recent statistics on SARS-CoV-2 infection, the WasterwaterScan dashboard, if there is a benefit to additional COVID vaccinations after the initial series, ISDA guideline for using anti-SARS-CoV-2 monoclonal an...
Nov 09, 2024•41 min•Ep. 1164
From the 2024 International Hepatitis B virus meeting in Chicago, TWiV speaks with Mala Maini and John Tavis about their careers, the replication and transmission of HBV, and the HBV Foundation. Hosts: Vincent Racaniello and Rich Condit Guests: Mala Maini and John Tavis Subscribe (free): Apple Podcasts , RSS , email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server Immunobiology and pathogenesis of hepatitis B virus infection (Nat Rev Immunol) HBV Foundation https://www.he...
Nov 03, 2024•57 min•Ep. 1163
In his weekly clinical update, Dr. Griffin informs us about “walking pneumonia”, the phase of the polio supplemental immunization campaign in Gaza, mpox circulation, the Marburg virus outbreak in Rwanda, the beginning of influenza season, before reviewing the recent statistics on SARS-CoV-2 infection, the WasterwaterScan dashboard, contrasting public health concerns between the US and the UK, if mRNA boosters affect mucosal immunity against SARS-CoV-2 infection, where to find PEMGARDA, a reminde...
Nov 02, 2024•48 min•Ep. 1162
TWiV reviews continuing expansion of poliovirus type 2, removal of influenza B/Yamagata from the vaccine, Nobel Prize for miRNAs, protective immune response with a adenovirus-associated virus vector expressing a computationally designed hemagglutinin, and viral gene drive during herpes simplex 1 infection in mice. Hosts: Vincent Racaniello , Alan Dove , Rich Condit , Kathy Spindler , and Brianne Barker Subscribe (free): Apple Podcasts , Google Podcasts , RSS , email Become a patron of TWiV! Link...
Oct 27, 2024•1 hr 50 min•Ep. 1161
In his weekly clinical update, Dr. Griffin informs us about mpox circulation, the Marburg virus outbreak in Rwanda, new recommendations for the RSV and pneumococcal vaccines by the CDC, the beginning of influenza season, before reviewing the recent statistics on SARS-CoV-2 infection, the WasterwaterScan dashboard, contrasting public health concerns between the US and the UK, what the risk of SARS-CoV-2 transmission is when indoors, the difference between NVX-CoV2327 and BNT162b2 for adolescents,...
Oct 26, 2024•41 min•Ep. 1160
Vincent travels to the Karolinska Institute in Stockholm to meet up with Niklas Björkström and Joakim Dillner to review their research on the endometrial immune system, and the plan to eliminate cervical cancer in Sweden. Host: Vincent Racaniello Guests: Niklas Björkström and Joakim Dillner Subscribe (free): Apple Podcasts , Google Podcasts , RSS , email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server Endometrial immune system variation (Sci Immunol) Immune defense in th...
Oct 20, 2024•1 hr 26 min•Ep. 1159
In his weekly clinical update, Dr. Griffin informs us about mpox circulation and new vaccine approval, the Marburg virus outbreak in Rwanda, and the largest outbreak of whooping cough in a decade before reviewing the recent statistics on SARS-CoV-2 infection, the WasterwaterScan dashboard, immunity among those over 65th following the 3rd dose of the COVID-19 mRNA vaccine, where to find PEMGARDA, a reminder of how and when to use steroids to treat COVID-19, how well the SARS-CoV-2 rapid antigen t...
Oct 19, 2024•45 min•Ep. 1158
TWiV reviews Marburg virus outbreak in Rwanda, cryo-EM based discovery of a parvovirus causing black wasting disease in farmed beetles, and a mosaic nanoparticle experimental vaccine that elicits cross-reactive sarbecovirus responses in pre-vaccinated animals. Hosts: Vincent Racaniello , Alan Dove , and Brianne Barker Subscribe (free): Apple Podcasts , Google Podcasts , RSS , email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server Marburg virus disease , Rwanda (WHO) Suspe...
Oct 13, 2024•1 hr 33 min•Ep. 1157
In his weekly clinical update, Dr. Griffin updates us about polio SIA campaign in Gaza, the durability of protection following administration of GSK’s recombinant antigen RSV vaccine, mpox in an Ugandan jail, the Marburg virus outbreak in Rwanda, before reviewing the recent statistics on SARS-CoV-2 infection, the WasterwaterScan dashboard, immunogenicity, reactogenicity and safety of different COVID-19 vaccine platforms, disease severity in those not previously vaccinated with those vaccinated b...
Oct 12, 2024•36 min•Ep. 1156
TWiV reviews mask effectiveness against respiratory infections, EEE death in NY State, viruses with zoonotic potential in farmed fur animals, and genetic tracing of market wild life and viruses at the Huanan Seafood Market, the epicenter of the COVID-19 pandemic. Hosts: Vincent Racaniello , Alan Dove , and Rich Condit Subscribe (free): Apple Podcasts , Google Podcasts , RSS , email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server Review confirms mask effectiveness ( origi...
Oct 06, 2024•1 hr 35 min•Ep. 1155
In his weekly clinical update, Dr. Griffin discusses the Marburg virus outbreak in Rwanda, the lack of immune durability following pertussis vaccination, recommendations for maternal vaccination and antibody therapy to protect against infant RSV, vaccine security for Mpox, before reviewing the recent statistics on SARS-CoV-2 infection, the WasterwaterScan dashboard, how to put on and take off PPE to avoid contamination, where to find PEMGARDA, a reminder of how and when to use steroids to treat ...
Oct 05, 2024•39 min•Ep. 1154
From the Viruses of Microbes meeting in Cairns, Australia, TWiV speaks with Krystyna and Rob about their research on using bacteriophages to treat bacterial infections. Hosts: Vincent Racaniello and Jolene Ramsey Guests: Krystyna Dabrowska and Rob Lavigne Subscribe (free): Apple Podcasts , Google Podcasts , RSS , email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server Viruses of Microbes 2024 Immune responses to phages (Front Immunol) Engineering bacteriolytic enzymes (Fro...
Sep 29, 2024•55 min•Ep. 1153
In his weekly clinical update, Dr. Griffin deep dives into the durability of the antibody response following mpox vaccination, vaccine security, global mpox circulation, the origins of SARS-CoV-2, including a list TWiV episodes and combatting scientific misinformation, before reviewing the recent statistics on SARS-CoV-2 infection, the WasterwaterScan dashboard, where to find PEMGARDA, a reminder of how and when to use steroids to treat COVID-19, what do when healthcare workers succumb to SARS-C...
Sep 28, 2024•58 min•Ep. 1152
TWiV reviews polio vaccination campaign in Gaza, viruses with zoonotic potential in farmed fur animals, low HPV vaccination in North Texas associated with high rates of cervical cancer, a large flavivirus genome that does not encode error correction machinery, and antiphage defense through inhibition of virion assembly. Hosts: Vincent Racaniello , Dickson Despommier, Alan Dove , and Jolene Ramsey Subscribe (free): Apple Podcasts , Google Podcasts , RSS , email Become a patron of TWiV! Links for ...
Sep 22, 2024•1 hr 44 min•Ep. 1151
In his weekly clinical update, Dr. Griffin dives into West Nile virus in New Jersey, poliovirus vaccination campaign in Gaza and Afghanistan, California dengue virus infections, children dying from flu, mpox vaccination procurement and antiviral usage, flu circulation in US, before reviewing the recent statistics on SARS-CoV-2 infection, finding a new wasterwater dashboard, if the monovalent XBB.1.5 COVID-19 vaccine is effective against circulating SARS-CoV-2 isolates, the need for nasal mucosal...
Sep 21, 2024•48 min•Ep. 1150
From the annual meeting of the American Society for Virology, Kathy and Brianne speak with Mary Estes about her career and the research of her laboratory on viruses that infect the gastrointestinal tract, including rotavirus and norovirus. Hosts: Kathy Spindler and Brianne Barker Guest: Mary Estes Subscribe (free): Apple Podcasts , Google Podcasts , RSS , email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server Diarrhea induced by rotavirus NSP4 (Science) Minimal infective ...
Sep 15, 2024•1 hr 5 min•Ep. 1149
In his weekly clinical update, Dr. Griffin dives into “pandemic potential” viruses isolated from farmed fur animals, how the mRNA and pox vectored vaccines against mpox spar against each other, how telehealth does managing mpox, and if prophylactic use of the anti-RSV monoclonal for infants is cost-effective before reviewing the recent statistics on SARS-CoV-2 infection, if viral load correlates to one vaccination status, where to find PEMGARDA, does administration of molnupiravir reduce symptom...
Sep 14, 2024•45 min•Ep. 1148
TWiV reviews multi-country outbreak of Mpox, first face covering ban in Nassau County NY, case of polio in India, more in US accept vaccine misinformation, other wartime diseases in Gaza besides polio, a new scientist run virus genome database, Mpox epidemiology and vaccine effectiveness in England, and metabolic immaturity and breastmilk bile acid metabolites determine heightened newborn vulnerability to norovirus diarrhea. Hosts: Vincent Racaniello , Rich Condit , and Brianne Barker Subscribe ...
Sep 08, 2024•1 hr 46 min•Ep. 1147
In his weekly clinical update, Dr. Griffin discusses seasonal influenza vaccine recommendations from the CDC, polio vaccine campaign securing mpox vaccine for Africa, and donating to reduce food insecurity in mpox affected areas before reviewing the recent statistics on SARS-CoV-2 infection, where to find PEMGARDA, when to use convalescent plasma, a reminder of how and when to use steroids to treat COVID-19, what do when healthcare workers succumb to SARS-CoV-2 infection, if vaccination against ...
Sep 07, 2024•38 min•Ep. 1146
