TWiV 1289: Building a better hepatitis B trap

This Week in Virology

Jan 18, 2026•1 hr 42 min•Ep. 1289

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Episode description

TWiV explains how the dengue virus protein NS1 alters Aedes aegypti midgut permeability and favors virus dissemination, and achieving a complete hepatitis B virus cure in chronic hepatitis B virus-infected humanized mice by using a capsid assembly modulator.

Hosts: Vincent Racaniello, Alan Dove, and Angela Mingarelli

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Links for this episode

Support science education at MicrobeTV
ASV 2026
Positions in Rosenfeld Lab (email)
Dengue virus NS1 alters mosquito midgut permeability (mBio)
HBV cure with a capsid assembly modulator (Cell Host Microbe)
Letters read on TWiV 1289
Timestamps by Jolene Ramsey. Thanks!

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Intro music is by Ronald Jenkees

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