This Week in Startups - podcast cover

This Week in Startups

Jason Calacanisthisweekinstartups.com
Jason Calacanis covers startups, tech, markets, media, and all the hottest topics in business and technology. He also interviews the world’s greatest founders, operators, investors, and innovators.

Episodes

Open-source vs. "ClosedAI," demoing new AI tools & more with Sunny Madra & Vinny Lingham | E1742

Sunny and Vinny are back to demo some new AI tools (14:08), discuss open-source vs. "ClosedAI" (38:45), and more! (0:00) Jason kicks off the show (1:31) Jason's trip to the UAE and Abu Dhabi's 30-year investment horizon (12:39) Miro - Sign up for a free account at https://miro.com/startups (14:08) Sunny demos ChatPDF and LLMs' future in the workforce (24:23) Lemon.io - Get 15% off your first 4 weeks of developer time at https://Lemon.io/twist (25:41) Google's new univer...

May 16, 20231 hr 8 min

Using AI to revolutionize video game development with Scenario CEO Emmanuel de Maistre | E1741

Emmanuel de Maistre joins Jason to demo Scenario’s AI-powered game asset generator (3:54) before breaking down future applications of Scenario’s technology. Then, Presh gives a presentation on how to build no-code apps (26:41). (0:00) Emmanuel de Maistre joins Jason (1:29) The cost of developing video games (3:54) Emmanuel demos Scenario (11:29) Vanta - Get $1000 off your SOC 2 at https://vanta.com/twist (12:45) Emmanuel demos Scenario continued, and the cost and use cases for this technology (2...

May 12, 202346 min

Building brands and community + influencer marketing that actually works with Dee Murthy | E1740

Dee Murthy joins Jason to discuss the origin of the Group Chat podcast before talking about his new startup, Ghost (1:44). They then delve into fostering a community, staying true to your brand, and more! (30:12) (0:00) Dee Murthy joins Jason (1:44) The Origin of Group Chat podcast (11:32) Embroker - Use code TWIST to get an extra 10% off insurance at https://Embroker.com/twist (13:06) The impact of the Group Chat podcast (18:49) The premise of Ghost (22:57) QuickNode - Get one month free by usi...

May 11, 20231 hr 1 min

Reid Hoffman on AI's "crescendo moment," regulation and real-world applications | E1739

Reid Hoffman joins Jason to discuss AI's current "crescendo moment," and its ability to amplify human capabilities (1:50). Then, they discuss AI regulation, real-world use cases, and much more! (25:55) (0:00) Reid Hoffman joins Jason (1:50) AI’s “crescendo moment,” (12:48) Release - Get your first month free at https://release.com/twist (14:20) AI's ability to amplify human capability (24:21) Microsoft for Startups Founders Hub - Apply in 5 minutes for six figures in discounts ...

May 10, 20231 hr 2 min

Box CEO Aaron Levie breaks down Box AI and generative AI’s impact on business | E1738

Aaron Levie joins Jason to discuss the launch of Box AI (19:13), AI as a platform shift, its potential effects on employment dynamics (25:53), and much more! (00:00) Aaron Levie joins Jason (4:12) Thoughts on the impact and pace of AI (6:54) Aaron's "Aha!" moment (10:02) Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://Squarespace.com/TWIST (11:33) Getting consent to use data from customers (13:50) Creating an AI model for ear...

May 09, 20231 hr

GPT-4 web browsing, plugin demos, AI layoffs + more with Sunny Madra & Vinny Lingham | E1737

Vinny and Sunny join Jason for another AI roundtable to demo ChatGPT’s web browsing capabilities (1:44), discuss AI’s effect on productivity and the workforce (13:53), demo Opus Clip and ChatGPT’s Zillow plugin (33:44), and more! (0:00) Vinny and Sunny join Jason (1:44) GPT-4 web browsing demo (9:10) Inside.com ’s AI strategy (12:22) LinkedIn Marketing - Get a $100 LinkedIn ad credit at https://linkedin.com/thisweekinstartups (13:53) AI’s effect on productivity and the workforce (23:36) Hyperice...

May 09, 202354 min

Mining asteroids with AstroForge CEO Matthew Gialich | E1736

AstroForge CEO Matthew Gialich joins Jason to discuss his startup’s lofty goal of mining Platinum Group Metals from asteroids (1:11). They discuss the recent launch of their Brokkr-1 space vehicle, the company’s road map to gather PGMs successfully from space, and SpaceX’s impact on the space industry (5:42). Then, Founder University’s Kelly Schricker gives a presentation on how to set up a fundraising process for your startup (31:51). (0:00) AstroForge’s Matthew Gialich joins Jason (1:11) The p...

May 05, 202346 min

Airbnb CEO Brian Chesky on early rejection, customer focus & AI’s future in hospitality | E1735

Airbnb CEO and Co-Founder Brian Chesky joins Jason to tell the story of Airbnb’s early startup struggles (1:29) and discuss how the company has restructured operations to heighten focus on the product and its customers (16:05). They dive into addressing customer complaints, hyper-focused marketing, the AI opportunity for Airbnb, and much more (40:26). (0:00) Airbnb’s Brain Chesky joins Jason (1:29) Brian’s experience with early rejection (14:48) Lemon.io - Get 15% off your first 4 weeks of devel...

May 04, 20231 hr 9 min

Uber earnings + using AI to revolutionize clinical trials w/ Unlearn.AI’s Charles Fisher | E1734

First up, Jason breaks down Uber’s huge Q1 results! (1:21) Then, Unlearn.AI CEO Charles Fisher joins to discuss the advancements his company is making in fast-tracking clinical trials (9:49), how machine learning is used in drug development (16:24), Unlearn’s business model (35:24), and more! (0:00) Jason kicks off the show (1:21) Uber’s Q1 earnings (8:31) QuickNode - Get one month free by using code TWIST at https://go.quicknode.com/twist (9:49) The foundation of Unlearn.AI (12:42) Unlearn.AI’s...

May 03, 202351 min

BuzzFeed vs Gawker, AI’s impact on the future of media, and more with Semafor’s Ben Smith | E1733

Jason is joined by Semafor Co-Founder and EIC Ben Smith to dive into his new book and explore the current state of media. They break down BuzzFeed vs Gawker, why media unions might not work (29:35), the future of journalism (36:54), and much more! (0:00) Jason kicks off the show (1:55) Semafor's Ben Smith joins Jason (4:27) Ben's career in media (6:19) The previous era of publishing (9:13) The significance of BuzzFeed and Gawker (13:49) LinkedIn Jobs - Post your first job for free at htt...

May 02, 20231 hr

Demoing the most innovative new ChatGPT features with Sunny Madra and Vinny Lingham | E1732

Sunny and Vinny are back to break down ChatGPT's latest innovation: the Code Interpreter. They demonstrate its capabilities with two separate datasets on EVs in America and US Bank Failures (10:58) before discussing how platforms like ChatGPT will revolutionize organizational efficiency (31:19). (0:00) Jason kicks off the show (2:06) ChatGPT's new code interpreter (9:24) OpenPhone - Start your free trial and get 20% off at https://openphone.com/twist (10:58) ChatGPT's Code Interprete...

May 01, 20231 hr 12 min

Big Tech earnings breakdown w/TechCrunch's Alex Wilhelm | E1731

TechCrunch's Alex Wilhelm joins Jason to break down the big tech's Q1 earning reports (0:53). They discuss Google's culture of entitlement, Microsoft's AI momentum, Meta's year of efficiency, how Amazon may be in for a few quarters of pain, and Snap's double-digit drop (21:11). (0:00) Nick kicks off the show (0:53) TechCrunch's Alex Wilhelm joins Jason (1:23) Reflecting on SVB contagion (3:48) First Republic Bank and BuzzFeed's stock (6:16) Uber's profits (8:2...

Apr 28, 20231 hr 16 min

Billy McFarland on Fyre Fest fraud, failure, hacking, & the long road back | E1730

Billy McFarland joins Jason to discuss the lessons he has learned from his Fyre Fest fraud, before discussing the festival’s origin story and what led him to winding up in jail (1:36). This leads to an all-encompassing conversation about Billy’s early days as an entrepreneur, his experience in prison, and if he is a changed man (13:46). (0:00) Jason kicks off the show (1:36) Reflecting on Fyre Festival (6:57) The origin of Billy’s charisma & communication (11:31) Billy’s first experience wit...

Apr 27, 20231 hr 4 min

AI’s Future: Opportunity, Regulation & Limits with Vinny Lingham & Sunny Madra | E1729

Vinny and Sunny join Jason to discuss the three phases of AI adoption and the emergence of new business models (1:55), which leads to a conversation about Grimes open-sourcing her AI-generated vocals before debating whether the government should regulate AI (24:57). They wrap with a conversation about AI’s technical constraints, OpenAI’s transparency issues, and the future of startups (39:31). (0:00) Show start (1:04) Vinny and Sunny join Jason (1:55) The three phases of AI adoption (11:15) Cach...

Apr 26, 20231 hr 14 min

Spotify earnings, Grimes takes AI-based music approach + Cafe X CEO Henry Hu | E1728

Jason starts the show by breaking down Spotify’s latest earnings report before discussing pop star Grimes taking to Twitter to announce a new business model for her AI-generated music (1:44). Then, Cafe X CEO Henry Hu joins Jason to discuss their latest equity crowdfund and being resilient, surviving a downturn, and more (18:22). (0:00) Jason kicks off the show (1:44) Spotify Earnings (8:25) Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://...

Apr 25, 202355 min

Building generative AI for pitch decks with Tome CEO Keith Peiris | E1727

Tome CEO Keith Peiris joins Jason to demo Tome’s AI-powered text-to-presentation platform (10:25). They discuss concerns about the pace of AI and the prevalence of 10x engineers (35:55), before Velocity Growth’s Jen Bryan breaks down how to get started with paid ads (47:19). (0:00) Jason kicks off the show (2:013) Tome CEO Keith Peiris joins Jason (5:27) Creating a pitch deck with Tome (8:48) Microsoft for Startups Founders Hub - Apply in 5 minutes for six figures in discounts at http://aka.ms/t...

Apr 24, 20231 hr

SpaceX's Starship launch, Tiger Global's 20% markdown + Ask Jason! | E1726

Jason recaps SpaceX's Starship rocket launch (2:06) and discusses BuzzFeed's 15% RIF and Fox News settling its Dominion Voting Systems lawsuit (9:11). He also covers Reddit's announcement to charge large AI companies for data and Tiger Global's $12.7B fund markdown (19:40). The show ends with another edition of Ask Jason (34:41). (0:00) Jason kicks off the show (2:06) Recapping Jason's experience at Space X's Starship launch (7:52) Pilot - Get 20% off the first 6 months a...

Apr 21, 202347 min

Startup pitch competition: Jason invests $25K | E1725

Jason hosts another pitch competition featuring two startups from our Founder University program! Apply for Founder University: https://course.founder.university⁠ (0:00) Jason kicks off the show (3:35) Jason and Presh describe who Founder University is for (8:35) Vanta - Get $1000 off your SOC 2 at ⁠https://vanta.com/twist (9:52) Alexandra Bellensweig pitches HumHum (22:15) Presh's thoughts on HumHum (26:47) CacheFly - Get 10 terabytes free by signing up at https://twist.cachefly.com (28:13)...

Apr 20, 20231 hr 2 min

Building the future of VFX and video editing with Runway CEO Cristóbal Valenzuela | E1724

Runway CEO Cristóbal Valenzuela joins Jason to discuss their suite of generative AI video editing tools (3:03), Runway's AI Film Festival and the rapid evolution of filmmaking (22:21), Runway's ability to lower the barrier to entry for aspiring filmmakers (36:05), and more! (0:00) Jason kicks off the show (3:03) What is Runway? (6:39) Runway's text-to-video demo (11:08) Clumio - Start a free backup, or sign up for a demo at https://clumio.com/twist (12:08) Latent Diffusion paper (16:...

Apr 19, 20231 hr 2 min

Google’s search engine “panic,” AI-generated hits, Coinbase considers leaving US market | E1723

Rachel is back to help Jason break down the news! First, they cover Google reportedly “panicking” over Samsung potentially switching to Bing as its device-default search engine, how Google can beat OpenAI/Microsoft,” and Project Magi” (1:43). Then, they discuss some recent AI-generated viral hits and what it means for the future of the music industry (21:48) before wrapping up on the possibility that Brian Armstrong may relocate Coinbase outside of the US (49:25). (0:00) Jason and Rachel tee up ...

Apr 18, 202358 min

Uizard’s Tony Beltramelli on text-to-UI & PMF + building a Notion CRM w/ Kelly Schricker | E1722

Uizard CEO Tony Beltramelli joins Jason to demo Uizard’s AI-powered UI designer (6:01) and discusses how he iterated on Uizard’s product-market fit and the competition it faces (21:20). Then, Kelly Schricker from Founder University breaks down how to choose a CRM and how to build one yourself in Notion (42:54)! (0:00) Jason kicks off the show (2:21) CEO of Uizard, Tony Beltramelli, joins Jason (6:01) Tony demos Uizard’s text-to-UI platform (13:52) Lemon.io - Get 15% off your first 4 weeks of dev...

Apr 17, 20231 hr 5 min

Hyfe’s Joe Brew on using AI to quantify coughs + Presh on generating content with ChatGPT | E1721

Hyfe CEO Joe Brew joins Jason to discuss quantifying cough to prevent the spread of disease. They break down how Hyfe’s technology works (2:48), how his company diagnoses diseases via audio and qualifying health data (14:47), before Presh joins to demonstrate how to easily create business content for your startup with ChatGPT (40:16). (0:00) Jason kicks off the show (2:48) How does Hyfe work? (9:03) Notion - Sign up for FREE at https://notion.com/jason (10:32) Acoustic AI and its potential (14:5...

Apr 14, 202357 min

The rise of AutoGPTs and AI anxieties with Sunny Madra and Vinny Lingham | E1720

Vinny and Sunny join Jason to discuss AI’s blistering pace and compare its development to other product launches (2:47). They also break down the anxiety artists and developers feel from AI automation (14:47), the rise of AutoGPTs, Twitter’s reported LLM project, and more (37:01). (0:00) Jason kicks off the show (2:47) The blistering pace of AI (9:44) Developer builds Flappy Bird in 1-hour (11:24) Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at ht...

Apr 13, 20231 hr 22 min

Copy.ai CEO Paul Yacoubian on keeping up with GPT’s rapid evolution & AI’s potential impact | E1719

Copy.ai Founder Paul Yacoubian joins Jason to break down the evolution and progress that OpenAI has made with its GPT LLMs (2:38) before discussing the radical shifts that AI will cause across most industries (20:46). They end the show with a demo of Copy.ai and the legal issues surrounding training datasets (48:54). (0:00) Jason kicks off the show (2:38) The evolution of GPT-2 to GPT-3 (8:16) Mercury - Apply in minutes and get up to $5M in FDIC insurance at https://mercury.com (9:45) How GPT su...

Apr 12, 20231 hr 12 min

Stanford & Google’s Westworld-like AI experiment, BloombergGPT, SF CRE collapse | E1718

Jason breaks down an AI experiment conducted by Google and Stanford researchers, where they created a simulated Sims-like video game with characters driven by AI (2:27). Then, he discusses Bloomberg announcing its own financially-focused LLM and what it means for analysts (21:58). He wraps with two quick hits about San Francisco’s dire commercial real estate situation and the collapse of an instant delivery startup (37:51). (0:00) Jason kicks off the show (2:27) Stanford and Google paper "G...

Apr 11, 202352 min

PrayingForExits on the state of VC, ZIRP fraudsters, revolutionary product launches & more | E1717

The man behind the anonymous accounts “prayingforexits” on Instagram and “@mrexits” on Twitter joins Jason for a jam-packed episode. Topics covered: what founders can learn from Logan Roy (2:29), what recent ZIRP fraudsters have in common (21:39), where GPT-4 ranks in terms of revolutionary product launches (31:28), AI’s impact moving forward, the state of VC (1:02:29), and so much more! (0:00) Jason kicks off the show (2:29) Succession, Logan Roy’s mentality & winning (9:22) Purpose-driven ...

Apr 11, 20231 hr 26 min

YC demo day valuation tensions, how VCs can find gems, Substack's performance & more | E1716

Jason breaks down the valuation tension surrounding YC demo days (2:36), how to get better prices on YC-equivalent startups (8:59), Garry Tan's response to complaints (15:18), and more! Then, Jason reacts to a law firm's leaked expectations list that went viral (29:29) before wrapping with some thoughts about Substack (41:59). (0:00) Jason tees up Friday's topics! (2:36) Understanding the valuation tension of YC's demo day; why some investors resent YC (8:59) Jason's three wa...

Apr 07, 202347 min

Satya Patel on the state of VC, flexible investing frameworks & converting to evergreen | E1715

Satya Patel joins Jason to discuss the economics of being a self-funded GP and the structure of their fund (6:51). Then, they have an all-encompassing discussion about the challenges of running Google today, the state of VC, and much more (15:44). Before wrapping, they discuss their investing frameworks and when and when they will not break them (43:29). (0:00) Nick kicks off the show (1:21) Satya's early days a Google (6:51) The economics of being a solo GP (9:29) Mercury - Apply in minutes...

Apr 06, 20231 hr 28 min

Startup pitch competition: Jason invests $25K | E1714

Jason hosts another pitch competition featuring three startups from our Founder University program! Apply for Founder University: https://course.founder.university (0:00) Nick kicks off the show (1:07) Introducing Founder University (7:14) Pitch 01: Xinyue Ma of Sticker (11:56) Vanta - Get $1000 off your SOC 2 at https://vanta.com/twist (13:00) Jason’s feedback for Sticker (15:07) Pitch 02: Joseph Homsy of Outmost (17:11) Jason’s feedback for Outmost (23:14) LinkedIn Jobs - Post your first job f...

Apr 05, 202359 min

Saudi Arabia discloses LP positions & SEC charges Frank founder with fraud | E1713

First up, Jason touches on Saudi Arabia’s Public Investment Fund disclosing which VC firms it has made LP investments in (2:48), which leads to him pondering the human rights issues and if founders care where their money comes from (18:52). Jason caps off the show by breaking down the SEC’s charges against Frank founder Charlie Javice for allegedly closing a $175M acquisition based on over 4M fake user accounts (30:18). (0:00) Jason kicks off today’s show (2:48) Saudi Arabia discloses LP positio...

Apr 04, 202347 min
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