Hosts: Vincent Racaniello , Michael Schmidt , Elio Schaechter and Michele Swanson . The TWiM team is amazed by the ocelloid, and an evolutionary battle for iron between mammalian transferrin and bacterial transferrin-binding protein. Subscribe to TWiM (free) on iTunes , Stitcher , RSS , or by email. You can also listen on your mobile device with the Microbeworld app . Links for this episode A unicellular camera-type eye structure (PLoS One) Escape from iron piracy (Science) Iron in infection and...
May 08, 2015•1 hr 6 min
Hosts: Vincent Racaniello , Michael Schmidt , Elio Schaechter and Michele Swanson . The TWiM team discusses evidence that serotonin synthesis is regulated by spore-forming members of the gut microbiota. Subscribe to TWiM (free) on iTunes , via RSS feed , by email or listen on your mobile device with the Microbeworld app . Links for this episode When antibiotic resistance in vitro falls short (STC) Gut microbiota control serotonin in mice (Cell) Serotonin biosynthesis (Wikipedia) Microbial endocr...
Apr 24, 2015•58 min
Hosts: Vincent Racaniello , Michael Schmidt , Elio Schaechter and Michele Swanson . The TWiMers discuss how aroma helps disperse yeast cells on insect vectors, and evidence that MRSA is transmitted within households. Subscribe to TWiM (free) on iTunes , via RSS feed , by email or listen on your mobile device with the Microbeworld app . Links for this episode Aroma promotes yeast dispersal on flies (Cell Rep) MRSA is transmitted within households (mBio) FAQ: The threat of MRSA (AAM) Image credit ...
Apr 01, 2015•1 hr 15 min
Hosts: Vincent Racaniello , Michael Schmidt , Elio Schaechter and Jo Handelsman . The TWiM team celebrates 100 episodes with a Talmudic question, and discussion of how a single mutation alters bacterial host tropism. Subscribe to TWiM (free) on iTunes , via RSS feed , by email or listen on your mobile device with the Microbeworld app . Links for this episode A single mutation alters bacterial tropism (Nat Gen) Talmudic question #104 (Small Things Considered) Principles of Microbial Diversity (AS...
Mar 18, 2015•51 min
Hosts: Vincent Racaniello Guests: Maria Julia Marinissen , Edward H. You , and David R. Howell Vincent meets up with Maria, Edward, and David at the ASM Biodefense and Emerging Infections Research meeting to talk about alternative careers for scientists. Subscribe to TWiM (free) on iTunes , via RSS feed , by email or listen on your mobile device with the Microbeworld app . A video version of this episode is available at microbeworld.org/twim Links for this episode: ASM Biodefense meeting FBI Bio...
Mar 04, 2015•1 hr 2 min
The TWiM crew ponders the question of how a bacterium finds its middle when dividing, then divulge the transfer of interbacterial antagonism genes to eukaryotes, where they may function in innate defense. Links for this episode: Size independent symmetric division (Nat Commun) How does a bacterium find its middle ? (Nat Struct Biol) Genes transferred from bacteria augment eukaryotic defenses (Cell) Antibacterial gene transfer (eLife) Letters read on TWiM #98 on TWiM 98 Visit microbeworld.org/twi...
Feb 19, 2015•59 min
The TWiM team reveal how bacteria in a shipworm’s gills help digest wood in the gut, and an approach that identifies a new antibiotic from the soil. Links for this episode: Gill bacteria enable a novel digestive strategy (PNAS) Killing bacteria without resistance (Nature) An irresistable newcomer (Nature) Peptidoglycan synthesis animation 10 x 20 initiative (IDSA) Longitude Prize Visit microbeworld.org/twim for more....
Feb 04, 2015•1 hr 14 min
Hosts: Vincent Racaniello . Special guest: Rob Knight Vincent meets up with Rob Knight to talk about the technology that has fueled his drive to sequence the Earth and its inhabitants. Check out the Microbeworld app . Links for this episode Microbes en masse (Nature) Obesity alters gut microbial ecology (PNAS) Sharing microbiome with dogs (eLife) Earth microbiome project (BMC Biology) Stability of gut micobiota (Science) Gut microbes and the brain (J Neurosci) Send your microbiology questions an...
Jan 21, 2015•55 min
Hosts: Vincent Racaniello . Special guest: Stanley Maloy Vincent meets up with Stan Maloy on the campus of San Diego State University to talk about his career in microbiology and his work as Dean of Science. Subscribe to TWiM (free) on iTunes , via RSS feed , by email or listen on your mobile device with the Microbeworld app . Links for this episode: Maloy lab Salmonella.org Microbial genetics course page Typhoid Mary Send your microbiology questions and comments (email or mp3 file) to twim@twiv...
Jan 09, 2015•1 hr 6 min
Vincent, Elio, and Michael discuss a symbiosis between a nitrogen-fixing cyanobacteria and a single-celled eukaryotic alga. Links for this episode: Unicellular cyanobacterium and alga symbiosis (Science) Diversity of nitrogen-fixing cyanobacterium and its host (Environ Micro) Talmudic Question #4 ( answer ) Talmudic Question #2 Coccolithophore (Wikipedia) Visit microbeworld.org/twim to view the complete shownotes and entire back catalog....
Dec 25, 2014•1 hr 7 min
Vincent, Elio, and Michael reveal that a soil-dwelling nematode can recognize and respond to a bacterial quorum sensing molecule through a sensory neuron.
Dec 11, 2014•57 min
Vincent, Elio, Michael and Michele discuss the possible eradication of wild poliovirus type 3, and how microsporidian parasites prevent locust swarming behavior.
Nov 27, 2014•1 hr 8 min
Vincent, Elio, and Michele review a study of the viruses and bacteria in commensal rats in New York City. Visit microbeworld.org/twim for complete show notes. Thanks for listening!
Nov 14, 2014•59 min
Vincent meets up with Laurene and David at the Annual Meeting of the Southern California Branch of the American Society for Microbiology, where they discuss how the Los Angeles County Department of Health is preparing for an outbreak of Ebola virus infection, and Cepheid’s game-changing, modular PCR system for the diagnosis of infectious diseases.
Oct 29, 2014•1 hr 2 min
Vincent, Michele, and Michael discuss how a gene from bacteria protects a tick from plant cyanide poisoning, and enhanced transmission of Streptococcus pneumoniae by influenza virus co-infection in mice.
Oct 15, 2014•1 hr 13 min
Michele speaks with members of the Department of Bacteriology at the University of Wisconsin - Madison, on the occasion of its designation as a Milestones in Microbiology site, where they discuss how the department has advanced the science and teaching of microbiology.
Oct 01, 2014•50 min
Vincent, Elio, and Michael explore the fossilization of archaeal lipids, and highlight the recent ICAAC in Washington, D.C.
Sep 17, 2014•1 hr 14 min
Hosts: Vincent Racaniello , Michael Schmidt , Elio Schaechter and Michele Swanson . Vincent, Elio, Michael, and Michele consider whether our eating behavior is manipulated by gastrointestinal microbiota, and an aphid gene of bacterial origin whose gene product encodes a protein that is transported to an obligate endosymbiont. Subscribe to TWiM (free) on iTunes , via RSS feed , by email or listen on your mobile device with the Microbeworld app . Links for this episode National Biosafety Stewardsh...
Sep 03, 2014•1 hr 12 min
Vincent, Elio, Michael, and Michele discuss the diel transcriptional rythmns of bacterioplankton communities in the ocean, and extensively drug resistant Pseudomonas in Ohio.
Aug 21, 2014•1 hr 18 min
In Melbourne, Australia Vincent speaks with David, Melanie, and Adam about their work on group A Streptococcus, Helicobacter pylori, and infections of Koalas with Chlamydia.
Aug 11, 2014•1 hr 9 min
Vincent, Michael, Elio and Michele review a new fluorogenic diagnostic test for tuberculosis bacteria, and the role of a metalloprotease in helping a fungus invade the central nervous system.
Jul 24, 2014•1 hr 19 min
Hosts: Vincent Racaniello , Michael Schmidt , Elio Schaechter and Michele Swanson . Vincent, Michael, Elio and Michele discuss how an endosymbiont betrays its aphid host to alert plant defenses, and a new immunosuppressive cell that allows infection of neonates. Subscribe to TWiM (free) on iTunes , via RSS feed , by email or listen on your mobile device with the Microbeworld app . Links for this episode Endosymbiont protein betrays aphid (PNAS) Plant immune system (Nature) Plant defenses against...
Jul 10, 2014•1 hr 12 min
Vincent, Michael, and Michele discuss how iron might disperse bacterial biofilms in carotid arterial plaques, and controlling Salmonella by modulating host iron homeostasis.
Jun 28, 2014•1 hr 11 min
Hosts: Vincent Racaniello , Elio Schaechter , and Michele Swanson . Vincent, Elio, and Michele discuss how to synthesize a designer yeast chromosome, and deciphering the genetic changes path that allowed Yersinia pestis to be transmitted by fleas. Links for this episode: Total synthesis of a yeast chromosome (Science) Evolution of Y. pestis to flea-borne transmission (Cell Host Micr) Proventricular valve (Wikipedia) Image : flea with Y. pestis proventricular mass Letters read on TWiM 80 Send you...
Jun 11, 2014•54 min
Vincent, Michael, and Michele review highlights of the 2014 General Meeting of the American Society for Microbiology in Boston, MA.
May 29, 2014•1 hr 12 min
Vincent, Elio, and Michael consider a fungal pathogen of insects that acquired a gene from its host that facilitates infection, and presence of gram-negative nosocomial pathogens on community surfaces near hospitals in Brooklyn.
May 15, 2014•1 hr 4 min
Vincent, Elio, Michael, and Michelle review how a pathogen promotes plant attractiveness to insect vectors, and activation of sensory neurons that modulate pain and inflammation by bacterial infection.
May 01, 2014•1 hr 8 min
Vincent, Elio, Michael, and Michelle discuss the use of bacteria to build a genetic sensor for heavy metals, and how host sugars help enteric pathogens to expand after antibiotic treatment.
Apr 11, 2014•1 hr 7 min
Vincent, Elio, Michael, and Michelle discuss a symbiosis between a bacterium and fungus that increases the virulence of oral biofilms, and the assembly of amyloid fibers, which are needed for biofilm formation.
Mar 27, 2014•1 hr 22 min
Vincent, Elio, and Michael discuss a huge 30,000 year old virus recovered from Siberia, and nested symbiosis facilitated by horizontal gene transfer from bacteria to insect.
Mar 12, 2014•1 hr 10 min
