TWiM #100: Omnis cellula e cellula
Episode description
Hosts: Vincent Racaniello, Michael Schmidt, Elio Schaechter and Jo Handelsman.
The TWiM team celebrates 100 episodes with a Talmudic question, and discussion of how a single mutation alters bacterial host tropism.
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Links for this episode- A single mutation alters bacterial tropism (Nat Gen)
- Talmudic question #104 (Small Things Considered)
- Principles of Microbial Diversity (ASM Press)
- Journal of Microbiology & Biology Education
- Letters read on TWiM 100
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Image: Yellow colonies of S. aureus on a blood agar plate, note regions of clearing around colonies caused by lysis of red cells in the agar By: HansN. on wikimedia. From the study (Nat Gen) "...only a single naturally occurring nucleotide mutation was required and sufficient to convert a human-specific S. aureus strain into one that could infect rabbits."