The Retina Channel Podcast - podcast cover

The Retina Channel Podcast

Keyvan Koushan, MD, FRCSCwww.theretinachannel.com
A journal club to review recent journal articles in the field of retina. The target audience are retina specialists and other healthcare professionals who want to stay up-to-date with the latest publications in the field of retina.
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Episodes

E57-PAMM and the Ischemic Cascade- Dr. David Sarraf

Dr. David Sarraf from UCLA discusses Paracentral Acute Middle Maculopathy (PAMM) and its the ischemic implications. Discussed article: Wang D, Au A, Duker JS, Sarraf D. PAMM and the ischemic cascade associated with radiation retinopathy. Am J Ophthalmol Case Rep. 2020 Sep 8;20:100918. doi: 10.1016/j.ajoc.2020.100918. PMID: 32984654; PMCID: PMC7495006.

Jan 17, 202214 min

E56-C5 Inhibitor Avacincaptad Pegol for Geographic Atrophy- Dr. Kourous Rezaei

Dr. Kourous Rezaei reviews the results of the GATHER1 trial on complement C5 inhibition for slowing down progression of geography atrophy in dry AMD. References article: Jaffe GJ, Westby K, Csaky KG, Monés J, Pearlman JA, Patel SS, Joondeph BC, Randolph J, Masonson H, Rezaei KA. C5 Inhibitor Avacincaptad Pegol for Geographic Atrophy Due to Age-Related Macular Degeneration: A Randomized Pivotal Phase 2/3 Trial. Ophthalmology. 2021 Apr;128(4):576-586. doi: 10.1016/j.ophtha.2020.08.027. Epub 2020 S...

Dec 24, 202130 min

E55-Minimized Eye Movement and Laser for RD Repair- Dr. Gregg Kokame

Dr. Kokame from the University of Hawaii reports a novel method of repairing certain types of retinal detachment using minimized eye movement followed by laser retinopexy. Referenced article: Kokame GT, Yee S, Omizo JN, Villanueva L, Liu J. Laser Treatment after Minimized Eye Movement for Repair of Retinal Detachment. Ophthalmol Retina. 2021 Sep;5(9):939-941. doi: 10.1016/j.oret.2021.01.014. Epub 2021 Jan 30. PMID: 33529816.

Nov 16, 202116 min

E54-Macular Hydrodissection, Scleral Needling and Preop Gas- Dr. Efrem Mandelcorn

Dr. Efrem Mandelcorn from the University of Toronto talks about 3 different surgical techniques that he's published in 3 different articles: 1. Macular hydodissection for challenging macular holes: Felfeli T, Mandelcorn ED. MACULAR HOLE HYDRODISSECTION: Surgical Technique for the Treatment of Persistent, Chronic, and Large Macular Holes. Retina. 2019 Apr;39(4):743-752. doi: 10.1097/IAE.0000000000002013. PMID: 29303907. 2. Scleral needling for closure of sclerotomies: Felfeli T, Altomare F, Mande...

Nov 02, 202144 min

E53-Optogenetic Vision Recovery for Retinitis Pigmentosa-Drs. Sahel and Roska

Professors Sahel and Roska describe partial visual recovery of a patient with advanced RP using optogenetic technology. Discussed article: Sahel JA, Boulanger-Scemama E, Pagot C, Arleo A, Galluppi F, Martel JN, Esposti SD, Delaux A, de Saint Aubert JB, de Montleau C, Gutman E, Audo I, Duebel J, Picaud S, Dalkara D, Blouin L, Taiel M, Roska B. Partial recovery of visual function in a blind patient after optogenetic therapy. Nat Med. 2021 Jul;27(7):1223-1229. doi: 10.1038/s41591-021-01351-4. Epub ...

Oct 05, 202130 min

E52-Complications of Acute PVD- Dr. Michael Seider

Dr. Seider elaborates on his group's large retrospective study on rates and risk factors for complicated acute posterior vitreous detachment. Full reference to the discussed article: Seider MI, Conell C, Melles RB. Complications of Acute Posterior Vitreous Detachment. Ophthalmology. 2021 Jul 27:S0161-6420(21)00552-2. doi: 10.1016/j.ophtha.2021.07.020. Epub ahead of print. PMID: 34324945.

Sep 20, 202140 min

E51-COVID-19 and anti-septics, Ocular Tissue Detection, & Ontario Surgical Backlog-Dr. Tina Felfeli

Dr. Tina Felfeli discusses 3 articles around COVID-19 and ophthalmology: (1) Effect of various concretions and exposure times of common ophthalmology anti-septics on COVID-19 infected cell lines. (2) Effect of the pandemic on the backlog of elective ophthalmic surgical cases in the province of Ontario, Canada (3) Detection of the COVID-19 virus in different ocular tissues of a patient that tested positive for COVID-19. Referenced articles: Felfeli T, Kasloff SB, Krishnan J, El-Defrawy SR, Mazzul...

Jul 19, 202143 min

E50-Vision Recovery Velocity, Momentum and Acceleration-Dr. David Almeida

Dr. Almeida presents a mathematical model based on Newtonian mechanics to discuss vision recovery of different anti-VEGF medications. The discussed article: Almeida DRP, Ruzicki J, Xu K, Chin EK. Vision Recovery Velocity, Momentum and Acceleration: Advanced Vitreoretinal Analytics as Measure of Treatment Efficacy for Neovascular Age-Related Macular Degeneration. Clin Ophthalmol. 2021 Jan 18;15:189-194. doi: 10.2147/OPTH.S288621. PMID: 33500611; PMCID: PMC7822233.

Jun 14, 202133 min

E49-SCREENROP Study. Refining ROP Screening Guidelines- Dr. Kourosh Sabri

Dr. Sabri discusses his group's analysis of various screening criteria to detect visually significant Retinopathy of Prematurity while minimizing unnecessary retinal exams. Discussed article: Sabri K, Shivananda S, Farrokhyar F, Selvitella A, Easterbrook B Kin B, Seidlitz W, Lee SK; Canadian Neonatal Network and the Canadian Association of Pediatric Ophthalmology and Strabismus. Refining evidence-based retinopathy of prematurity screening guidelines: The SCREENROP study. Paediatr Child Health. 2...

May 28, 202147 min

E48-DRCR Protocol W 2-year Results: Prophylactic anti-VEGF for Mod-Severe NPDR

Dr. Raj Maturi from the DRCR Retina Network discusses effect of early anti-VEGF injections in moderate-severe NPDR to prevent vision-threatening complications of diabetic retinopathy. This is the 2-year results of a 4-year study. Discussed article: Maturi RK, Glassman AR, Josic K, Antoszyk AN, Blodi BA, Jampol LM, Marcus DM, Martin DF, Melia M, Salehi-Had H, Stockdale CR, Punjabi OS, Sun JK; DRCR Retina Network. Effect of Intravitreous Anti-Vascular Endothelial Growth Factor vs Sham Treatment fo...

Apr 20, 202132 min

E47-Nondamaging Retinal Laser for Mac Tel Type II- Dr. Daniel Lavinsky

Dr. Daniel Lavinsky describes the results of a small randomized controlled clinical trial investigating functional and anatomical outcomes of using nondamaging retinal laser for the treatment of macular telangiectasia type II. The discussed article: Lavinsky D, Silva MOD, Chaves AE, Schneider WFM, Lavinsky F, Palanker D. FUNCTIONAL AND STRUCTURAL EFFECTS OF NONDAMAGING RETINAL LASER THERAPY FOR MACULAR TELANGIECTASIA TYPE 2: A Randomized Sham-Controlled Clinical Trial. Retina. 2021 Mar 1;41(3):4...

Mar 13, 202142 min

E46- DRCR Protocol AB. Anti-VEGF vs PPV for PDR w Vit Heme-Dr. Andrew Antoszyk

Dr. Antoszyk from the DRCR Retina Network discusses Protocol AB, which compared anti-VEGF injections vs immediate pars plana vitrectomy for the treatment of vitreous hemorrhage due to proliferative diabetic retinopathy. The discussed article: Antoszyk AN, Glassman AR, Beaulieu WT, Jampol LM, Jhaveri CD, Punjabi OS, Salehi-Had H, Wells JA 3rd, Maguire MG, Stockdale CR, Martin DF, Sun JK; DRCR Retina Network. Effect of Intravitreous Aflibercept vs Vitrectomy With Panretinal Photocoagulation on Vis...

Feb 13, 202122 min

E45- Stress in Medicine- Book Club with Dr. Nina Ahuja

Dr. Nina Ahuja (@docsleadership) discusses her newly published booked titled "Stress in Medicine, Lessons Learned Through my Years as a Surgeon, from Med School to Residency, and Beyond". In an intimate account of her journey through her medical career, Dr. Ahuja discusses some of hardships and difficulties that she has gone through with the goal of bringing more transparency to the medical education and breaking the culture of silence. The book is available through Amazon and Apple Books....

Jan 27, 202132 min

E44- Representation of Women in Vitreoretinal Meetings- Dr. Jay Sridhar

Dr. Sridhar (host of the Straight from the Cutter's Mouth podcast) discusses his recent article on the trends of women's representation in VR meetings in the US between 2015 and 2019. The discusses article: Sridhar J, Kuriyan AE, Yonekawa Y, Berrocal A, Khan MA, Chan RVP, Haller JA. Representation of Women in Vitreoretinal Meeting Faculty Roles from 2015 through 2019. Am J Ophthalmol. 2021 Jan;221:131-136. doi: 10.1016/j.ajo.2020.09.001. Epub 2020 Sep 9. PMID: 32918901; PMCID: PMC7736466....

Dec 24, 202025 min

E43- Retinal Findings in Hospitalized COVID-19 Patients- Dr. Leonardo Pereira

Dr. Pereira speaks about his group’s report on retinal findings in patients with severe COVID-19 infections who were admitted in the ICU. Discussed article: Pereira LA, Soares LCM, Nascimento PA, et al. Br J Ophthalmol Epub ahead of print: [please include Day Month Year]. doi:10.1136/bjophthalmol- 2020-317576

Dec 03, 202017 min

E42-Peripheral Exudative Hemorrhagic Chorioretinopathy- Dr. Federico Zicarelli

Dr. Zicarelli discusses his group's 10-yr retrospective analysis on the prognostic factors associated with Peripheral exudative hemorrhagic chorioretinpathy. Discussed article: Zicarelli F, Preziosa C, Staurenghi G, Pellegrini M. Peripheral exudative haemorrhagic chorioretinopathy: a widefield imaging study. Br J Ophthalmol. 2020 Sep 3:bjophthalmol-2020-317083. doi: 10.1136/bjophthalmol-2020-317083. PMID: 32883656

Nov 02, 202027 min

E41- Treatment of Secondary Macular Holes with Topical Therapy- Dr. John Niffenegger

Dr. Niffenegger discusses a case series of secondary macular hole treatment with topical therapy. Discussed article: Niffenegger JH, Fong DS, Wong KL, Modjtahedi BS. Treatment of Secondary Full-Thickness Macular Holes with Topical Therapy. Ophthalmol Retina. 2020 Jul;4(7):695-699. doi: 10.1016/j.oret.2020.01.014. Epub 2020 Jan 28. PMID: 32284268.

Oct 05, 202016 min

E40-Retinal Vasculitis and Intraocular Inflammation with Brolucizumab - Dr. Caroline Baumal

Dr. Baumal discusses features and outcomes of eyes with retinal vasculitis and intraocular inflammation after intravitreal injection of brolucizumab for treatment of neovascular age-related macular degeneration. Discussed article: Baumal CR, Spaide RF, Vajzovic L, et al. Retinal Vasculitis and Intraocular Inflammation after Intravitreal Injection of Brolucizumab [published online ahead of print, 2020 Apr 25]. Ophthalmology . 2020;S0161-6420(20)30371-7. doi:10.1016/j.ophtha.2020.04.017...

Sep 07, 202028 min

E39- Slit Lamp Shields and Face Masks for COVID-19. Dr. Victor Koh

Dr. Koh from Singapore National University Hospital discusses his team's simulation study on aerosol transmission through slit lamp shields and face masks. Discussed article: Chuan OS, Bin Razali MA, Shaffiee L, Xing YJ, Yin Fei TT, Chee LS, Koh V, Do slit lamp shields and face masks protect ophthalmologists amidst COVID-19?, Ophthalmology (2020), doi: https://doi.org/10.1016/j.ophtha.2020.06.031.

Aug 22, 202020 min

E38-Retinal Biomarkers of Alzheimer's Disease- Drs. Cecilia Lee and Rajendra Apte

Drs. Lee and Apte discuss their recent paper on our current understanding of using retinal imaging biomarkers to evaluate Alzheimer's disease. Discussed article: Lee CS, Apte RS, Retinal Biomarkers of Alzheimer’s Disease, American Journal of Ophthalmology (2020), doi: https://doi.org/10.1016/j.ajo.2020.04.040.

Jul 14, 202032 min

E37- Retinal Detachment Rates after Intravitreal Anti-VEGF Injections- Dr. Omesh Gupta

Dr. Gupta discusses findings of this large retrospective study on the risk and associations of rhegmatogenous retinal detachment after intravitreal anti-VEGF injections. Discussed article: Storey PP, Pancholy M, Wibbelsman TD, et al. Rhegmatogenous Retinal Detachment after Intravitreal Injection of Anti-Vascular Endothelial Growth Factor. Ophthalmology . 2019;126(10):1424‐1431. doi:10.1016/j.ophtha.2019.04.037

Jun 08, 202027 min

E36- COVID-19 and Preparedness among Ophthalmologists- International Panel Discussion. Drs. Dan Ting, Olivia Li and Steven Yeh

In a panel discussion with Dr. Koushan, Drs. Daniel Ting, Olivia Li and Steven Yeh discuss the preparedness of ophthalmologists in the COVID-19 crisis. The discussion is based on the most recent Ophthalmology editorial: Preparedness among Ophthalmologists: During and Beyond the COVID-19 Pandemic. Olivia Li, Ji-PengWong, Tien Y.Wong, Edmund Y.Mehta, JodLin, HaotianLin, XiaofengStrouthidis, Nicholas G.Park, Ki HoFung, Adrian T.McLeod, Stephen D.Busin, MassimoParke, David W.Holland, Gary N.Chodosh,...

Apr 20, 202057 min

E35- COVID-19 Mortality and Public Mask Usage- Dr. Christopher Leffler

Dr. Leffler discusses his team's analysis of the country-wide mortality from COVID-19 pandemic and its correlation with mask usage by the public. Full reference: Leffler CT, Ing E, McKeown CA, Pratt D, Grzybowski A. Final Country-wide Mortality from the Novel Coronavirus (COVID-19) Pandemic and Notes Regarding Mask Usage by the Public. April 4, 2020. Available from: researchgate.net.

Apr 06, 202028 min

E34- Progression of glaucoma after anti-VEGF injections in susceptible eyes- Dr. Eugene Shildkrot

Dr. Shildkrot discusses progression of glaucomatous changes in 28 eyes that were receiving anti-VEGF injections. Discussed article: Effects of Intravitreal Anti-VEGF Therapy on Glaucoma-like Progression in Susceptible Eyes, Du, Jeanette MD; Patrie, James T ; Prum, Bruce E.; Netland, Peter A.; Shildkrot, Yevgeniy (Eugene) MD, Journal of Glaucoma: December 2019 - Volume 28 - Issue 12 - p 1035-1040 doi: 10.1097/IJG.0000000000001382

Mar 29, 202023 min

LEAVO Trial - Comparison of Anti-VEGF drugs for Macular Edema Secondary to CRVO- Dr. Philip Hykin.

Dr. Philip Hykin discusses the LEAVO trial which was a large prospective trial comparing the efficacy of three main anti-VEGF intravitreal injections (bevacizumab, ranibizumab and aflibercept) for treating macular edema secondary to Central Retinal Vein Occlusion. The discussed article: Clinical Effectiveness of Intravitreal Therapy With Ranibizumab vs Aflibercept vs Bevacizumab for Macular Edema Secondary to Central Retinal Vein Occlusion: A Randomized Clinical Trial. Hykin P, Prevost AT, Vasco...

Feb 27, 202026 min

E32-Change in Management after Vitreous Culture in Endophthalmitis after Intravitreal Injections-Dr. James Vander

Dr. Vander from Wills Eye Hospital discusses the effect of vitreous tap on the management of 60 cases of endophthalmitis post intravitreal anti-VEGF injections. The discussed article: Changes in Management Based on Vitreous Culture in Endophthalmitis After Intravitreal Anti-vascular Endothelial Growth Factor Injection. Patel SN, Storey PP, Pancholy M, Obeid A, Wibbelsman TD, Levin H, Hsu J, Garg SJ, Dunn JP, Vander JF. Am J Ophthalmol. 2019 Nov;207:224-231. doi: 10.1016/j.ajo.2019.06.008. Epub 2...

Jan 28, 202022 min

E31- FLUID Study - Dr. Robyn Guymer

Dr. Guymer discusses the results of the FLUID study which investigated whether some residual sub retinal fluid can be tolerated in neovascular macular degeneration. Full reference: Tolerating Subretinal Fluid in Neovascular Age-Related Macular Degeneration Treated with Ranibizumab Using a Treat-and-Extend Regimen. Guymer, Robyn H.Chang, Andrew et al. Ophthalmology, Volume 126, Issue 5, 723 - 734

Dec 10, 201917 min

E29-Anti-VEGF Levels in Breast Milk after Intravitreal Injections-Drs. Muni and Juncal

Drs. Muni and Juncal discuss their case series on the level of anti-VEGF drugs and VEGF-A levels on lactating mothers who had received intravitreal anti-VEGF injections. Reference for the article: Ranibizumab and Aflibercept Levels in Breast Milk after Intravitreal Injection; Verena R. Juncal,Quratulain Paracha,Motaz Bamakrid, ,Carolina L.M. Francisconi, Julia Farah, Amin Kherani ,Rajeev H. Muni; Ophthalmology, published on line Sep.11, 2019 https://doi.org/10.1016/j.ophtha.2019.08.022...

Sep 14, 201922 min
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