This episode is another retina-focused EyeNovation episode featuring Prof. Robyn Guymer who presented an in-depth discussion on the SIRE sign, assessment of visual function in Geographic atrophy and also current GA trials and treatments. YouTube link: https://youtu.be/p-R4_OsuGKE
This episode is a reproduction of the second retina-focused EyeNovation webinar series and a result of a special collaboration between Canadian Retina Society and Canadian Ophthalmological Society. Dr. Angie Fong from the University of Hong Kong gives a fantastic overview of pachychoroid spectrum of conditions with a focus on central serous chorioretinopathy and polypoidal choroidal vasculopathy. She gives an in-depth review of pathogenesis, recent clinical trials, and emerging management strate...
Dr. Wu discusses prospective cognitive outcomes of children who had treatment for Retinopathy of Prematurity. The analysis suggests that cognitive outcomes were similar for children who had either laser or anti-VEGF injections for ROP treatment. Dr. Wu will be one of the invited guest speakers at the Canadian Retina Society meeting in Vancouver, BC from April 25-April 27, 2025. You can register for this meeting at: https://crsscr.ca/meeting Discussed article: Wu PL, Shih CP, Huang YS, Chen HC, H...
This episode is a recording of the retina-focused EyeNovation webinar episode which was a collaboration between Canadian Ophthalmological Society and the Canadian Retina Society. Dr. Chakravarthy will provide a background to the double layer sign, its definition and how it is detected. Data to support the presentation will be from the EDNA trial . This study possesses an imaging dataset that was captured longitudinally in over 500 high risk eyes and obtained robust rates of progression to neovas...
In this episode, Dr. Muni discusses two of his recent publications on repair of retinal detachment. In the first article, he discusses long-term reattachment rates of patients that were studied in the PIVOT trial, showing that both groups of patients who underwent either pneumatic retinopexy or vitrectomy had excellent long-term attachment rates. In the second article, he discusses Suprachoroidal Viscopexy, which is a novel in-office method of repairing retinal attachment, using viscoelastic age...
Dr. Cindy Chen describes her group’s work on a retrospective review of association of systemic methotrexate therapy and a lower rate of proliferative vitreoretinopathy (PVR) after retinal detachment repair in large cohort of 2674 eligible patients.
Professor Maher Saleh discusses his group’s findings for the use of perfluorocarbon in the treatment of macula-off retinal detachment. The study results suggest that perfluorocarbon liquid use during vitrectomy for macula-Off Retinal detachment has no impact on Macular folds and Metamorphopsia. Discussed article: Wurtz M, Dormegny L, Muller C, Bourcier T, Ballonzoli L, Gaucher D, Saleh M. PERFLUOROCARBON LIQUID USE DURING VITRECTOMY FOR MACULA-OFF RETINAL DETACHMENT HAS NO IMPACT ON MACULAR FOLD...
Dr. Marc Spirn from Wills Eye Hospital discusses the results of a retrospective study of performing lattice degeneration on a series of patients who had lattice degeneration with high risk features. The discussed article: Kazan AS, Mahmoudzadeh R, Salabati M, Sharpe J, Fineman MS, Hsu J, Yonekawa Y, Spirn MJ. Indications and Outcomes of Laser Retinopexy in Eyes With High-Risk Lattice Degeneration. J Vitreoretin Dis. 2024 Apr 25;8(4):381-387. doi: 10.1177/24741264241248253. PMID: 39148566; PMCID:...
Dr. Witkin from the American Society of Retina Specialists talks about our current knowledge of the incidence of retinal vasculitis following intravitreal injection of Pegcetacoplan for treatment of geographic atrophy. Discussed article: Witkin AJ, Jaffe GJ, Srivastava SK, Davis JL, Kim JE. Retinal Vasculitis After Intravitreal Pegcetacoplan: Report From the ASRS Research and Safety in Therapeutics (ReST) Committee. J Vitreoretin Dis. 2023 Dec 21;8(1):9-20. doi: 10.1177/24741264231220224. Erratu...
A panel of guests optometrists share their feedback about communication issues between optometry and the speciality of retina. Guests panelists: Dr. George Papadakis, Dr. Brian Feinstein, Dr. Lena Moiseiykina and Dr. Nagar Sohbati.
Dr. Arthur sit describes his surprising research results on the effect of scleral buckle on ocular fluid dynamics. The discussed article: Lyons LJ, Kazemi A, Bakri SJ, Barkmeier AJ, Iezzi R, Olsen TW, Hodge DO, Sit AJ. The Effect of Scleral Buckle Surgery on Tonographic Outflow Facility, Positional Intraocular Pressure, and Ocular Biomechanics. Ophthalmol Glaucoma. 2024 Jan-Feb;7(1):1-7. doi: 10.1016/j.ogla.2023.07.007. Epub 2023 Jul 22. PMID: 37482122.
Dr. Paul Micevych from the UC San Francisco discusses his group's work on systemic and individual risk factors leading to complicated diabetic retinopathy requiring vitrectomy. Discussed article: Micevych PS, Taha AM, Poddar A, Stewart JM. Individual and Systems-Based Risk Factors for Diabetic Vitrectomy in an Urban Safety-Net Hospital. Ophthalmol Retina. 2023 Dec;7(12):1027-1034. doi: 10.1016/j.oret.2023.05.014. Epub 2023 May 24. PMID: 37236319.
Dr. Nina Ahuja and Dr. Nupura Bakshi elaborate on the concept of Equity, Diversity and Inclusion in medicine and discuss their recent publication about the EDI landscape in the Canadian ophthalmology post-secondary programs. The discussed article: Lee EY, Farrokhyar F, Bakshi N, Levin LA, Ahuja N. Equity, diversity, and inclusion landscape in Canadian postgraduate medical education for ophthalmology. Can J Ophthalmol. 2024 Feb;59(1):31-39. doi: 10.1016/j.jcjo.2022.08.015. Epub 2022 Sep 24. PMID:...
Dr. Sarraf talks about his group's work on the correlation of PED size and variablity and the visual improvement during the treatment of neovascular AMD as analyzed using data from HAWK and HARRIER studies. Referenced article: Sarraf D, Khanani AM, Sadda SR, Chang A, Wong DT, Kempf AS, Saffar I, Tang S, Tadayoni R. PIGMENT EPITHELIAL DETACHMENT THICKNESS AND VARIABILITY AFFECTS VISUAL OUTCOMES IN PATIENTS WITH NEOVASCULAR AGE-RELATED MACULAR DEGENERATION. Retina. 2024 Jan 1;44(1):10-19. doi: 10....
Dr. Jong Park discusses surgical mananement of full-thickness macular holes associated with macular telangiectasia. Referenced article: Park JG, Adrean SD, Begaj T, Capone A Jr, Charles S, Chen SN, Chou HD, Cohen MN, Corona ST, Faia LJ, Garg SJ, Garretson BR, Gregori NZ, Haller JA, Houghton OM, Hsu J, Jo J, Kaiser RS, Lai CC, Mahgoub MM, Mansoor M, Matoba R, Morizane Y, Nehemy MB, Raphaelian PV, Regillo CD, Ruby AJ, Runner MM, Sneed SR, Sohn EH, Spirn MJ, Vander JF, Wakabayashi T, Wolfe JD, Wyko...
Dr. Landon Rohowetz discusses his group's findings of a retrospective analysis of the characteristics of Retinal Detachment cases that were associated with Retinal Dialysis. Discussed article: Rohowetz LJ, Jabbehdari S, Smiddy WE, Berrocal AM, Townsend JH, Chang JS, Yannuzzi N, Sridhar J, Haddock LJ, Fortun JA, Flynn HW Jr; Retinal Dialysis Study Group. Retinal Detachment Associated with Retinal Dialysis: Clinical Features and Outcomes of Surgery in a 10-Year Study. Ophthalmol Retina. 2023 Oct;7...
Dr. Jabs and Dr. Acharya discuss the results of the MERIT trial that investigated relative efficacy of intrvitreal injections of Dexamethasone implant vs ranibizumab vs methotrexate for the treatment of macular oedema associated with uveitis. Discussed article: Multicenter Uveitis Steroid Treatment Trial (MUST) Research Group, Writing Committee:; Acharya NR, Vitale AT, Sugar EA, Holbrook JT, Burke AE, Thorne JE, Altaweel MM, Kempen JH, Jabs DA. Intravitreal Therapy for Uveitic Macular Edema-Rani...
Prof. Gemmy Cheung from the National University of Singapore and Singapore National Eye Center discusses her research results on progression of Geographic Atrophy on Asian vs non-Asian Eyes. References Article: Teo KYC, Fujimoto S, Sadda SR, Kokame G, Gomi F, Kim JE, Cheng MFS, Corradetti G, Amornpetchsathaporn A, Chainakul M, Lee WK, Lai TYY, Ruamviboonsuk P, Cheung CMG. Geographic Atrophy Phenotypes in Subjects of Different Ethnicity: Asia-Pacific Ocular Imaging Society Work Group Report 3. Op...
Dr. Regillo describes the results of the phase 3 prospective study of Ranibizumab Port Delivery System (PDS) for the treatment of neovascular AMD. Reference Article: Regillo C, Berger B, Brooks L, Clark WL, Mittra R, Wykoff CC, Callaway NF, DeGraaf S, Ding HT, Fung AE, Gune S, Le Pogam S, Smith R, Willis JR, Barteselli G. Archway Phase 3 Trial of the Port Delivery System with Ranibizumab for Neovascular Age-Related Macular Degeneration 2-Year Results. Ophthalmology. 2023 Jul;130(7):735-747. doi:...
Dr. Smiddy presents a cost analysis of the step therapy for treatment of diabetic macular edema based on DRCR protocol AC results. Discussed article: Patel NA, Al-Khersan H, Yannuzzi NA, Lin J, Smiddy WE. Aflibercept Monotherapy versus Bevacizumab-First for Diabetic Macular Edema: A Cost Analysis Based on Diabetic Retinopathy Clinical Research Network Protocol AC Results. Ophthalmol Retina. 2023 May;7(5):413-419. doi: 10.1016/j.oret.2022.11.010. Epub 2022 Nov 22. PMID: 36423893....
Dr. Jason Hsu from Wills Eye Hospital returns to The Retina Channel to discuss his groups' retrospective study of eyes with advanced retinal detachement (PVR grade C or worse) that underwent retinectomy without lensectomy. Their study showed that 75% of these eyes at 3 months (and 68% at 6 months) had single surgery anatomic success. The study is suggestive that lensectomy and even peripheral vitreous base sheving may not be necessary when doing retinectomy for advanced RD cases. Full reference ...
Dr. Jay Duker speaks about the results of the DAVIO trial which was a phase 1 trial investigating an intravitreal implant (EYP-1901) containg vorolanib (a VEGF and receptor blocker) in a bioerodible Durasert implant for the treatment of wet AMD.
Dr. Noemi Lois from Queens University in Belfast, UK discusses results of the DIAMONDS study, which was a prospective trial that looked into the effectiveness, safety, and cost-effectiveness of subthreshold micropulse laser (SML), compared with standard laser (SL), for diabetic macular edema (DME) with central retinal thickness (CRT) < 400 um. Referenced article: Lois N, Campbell C, Waugh N, Azuara-Blanco A, Maredza M, Mistry H, McAuley D, Acharya N, Aslam TM, Bailey C, Chong V, Downey L, Ele...
Dr. Xuejing Chen discusses her group's retrospective analysis of the incidence and risk factors of delayed retinal breaks following a symptomatic posterior vitreous detachment. Discussed article: Jindachomthong KK, Cabral H, Subramanian ML, Ness S, Siegel NH, Chhablani J, Hsu SX, Chen X. Incidence and risk factors for delayed retinal tears following an acute, symptomatic posterior vitreous detachment. Ophthalmol Retina. 2022 Oct 25:S2468-6530(22)00514-0. doi: 10.1016/j.oret.2022.10.012. Epub ahe...
Dr. Jhavery discusses results of DRCR Retina Protocol AC study which compared DME response to anti-VEGF injections in patients who received Aflibercept monotherapy vs those who started with Bevacizumab first and then switched to Aflibercept if needed. Discussed article: Jhaveri CD, Glassman AR, Ferris FL 3rd, Liu D, Maguire MG, Allen JB, Baker CW, Browning D, Cunningham MA, Friedman SM, Jampol LM, Marcus DM, Martin DF, Preston CM, Stockdale CR, Sun JK; DRCR Retina Network. Aflibercept Monotherap...
Dr. J. Fernando Arevalo discusses results of an international multicenter study that compared surgical success rates of vitrectomy vs vitrectomy + scleral buckle to repair retinal detachments due to giant retinal tears. The study collected 200 patients data over a 12 year period. Referenced article: Ong SS, Ahmed I, Gonzales A, Al-Fakhri AS, Al-Subaie HF, Al-Qhatani FS, Alsulaiman SM, Mura M, Maia M, Kondo Kuroiwa DA, Maia NT, Berrocal MH, Wu L, Zas M, Francos JP, Cubero-Parra JM, Arsiwala LT, H...
Dr. Finn discusses her groups' case series on temporal associattion CRVO and HRVO in young healthy patients after COVID-19 infection. Discussed article: Ashkenazy N, Patel NA, Sridhar J, Yannuzzi NA, Belin PJ, Kaplan R, Kothari N, Benitez Bajandas GA, Kohly RP, Roizenblatt R, Pinhas A, Mundae R, Rosen RB, Ryan EH Jr, Chiang A, Chang LK, Khurana RN, Finn AP. Hemi- and Central Retinal Vein Occlusion Associated with COVID-19 Infection in Young Patients without Known Risk Factors. Ophthalmol Retina....
Dr. Birger Lindtjørn from Norway discusses his team's prospective trial on comparison of SF6 vs air tamponade in vitrectomy for closure of small-medium macular holes. Discussed article: Lindtjørn B, Krohn J, Haugstad M, Stene-Johansen I, Austeng D, Basit S, Fossen K, Varhaug P, Kvaløy JT, Forsaa VA. Air versus Sulfur Hexafluoride Gas Tamponade for Small and Medium-Sized Macular Holes: A Randomized Noninferiority Trial. Ophthalmol Retina. 2022 Apr 7:S2468-6530(22)00179-8. doi: 10.1016/j.oret.2022...
Prof. Guymer from Melbourne Univeristy discusses finding of a prospective study on absence of association between retinal pseudodrusen and advanced AMD. Discussed article: Wu Z, Kumar H, Hodgson LAB, Guymer RH. Reticular Pseudodrusen on the Risk of Progression in Intermediate Age-Related Macular Degeneration. Am J Ophthalmol. 2022 Mar 11:S0002-9394(22)00101-5. doi: 10.1016/j.ajo.2022.03.007. Epub ahead of print. PMID: 35288077.
Dr. Ballios discusses his group's findings on novel mutations in the RCBTB1 gene that can cuase late-onset non-syndromic retinal dystrophies mimicking macular degeneration. Full article: Catomeris AJ, Ballios BG, Sangermano R, Wagner NE, Comander JI, Pierce EA, Place EM, Bujakowska KM, Huckfeldt RM. Novel RCBTB1 variants causing later-onset non-syndromic retinal dystrophy with macular chorioretinal atrophy. Ophthalmic Genet. 2022 Jan 20:1-8. doi: 10.1080/13816810.2021.2023196. Epub ahead of prin...
