Episode description

Pharmaceutical breakthroughs such as antibiotics and vaccines rank among some of the greatest advancements in human history. Yet exorbitant prices for life-saving drugs, safety recalls affecting tens of millions of Americans, and soaring rates of addiction and overdose on prescription opioids have caused many to lose faith in drug companies. Now, Americans are demanding a national reckoning with a monolithic industry. Pharma introduces brilliant scientists, incorruptible government regulators, and brave whistleblowers facing off against company executives often blinded by greed. A business that profits from treating ills can create far deadlier problems than it cures. Addictive products are part of the industry’s DNA, from the days when corner drugstores sold morphine, heroin, and cocaine, to the past two decades of dangerously overprescribed opioids. Pharma also uncovers the real story of the Sacklers, the family that became one of America’s wealthiest from the success of OxyContin, their blockbuster narcotic painkiller at the center of the opioid crisis. Pharma reveals how and why American drug companies have put earnings ahead of patients. Shermer and Posner also discuss:

• how Big Pharma companies conspire to hack the FDA regulations,
• parsing responsibility for the Opioid crisis between manufacturers, distributors, doctors, and patients,
• the physiology of addiction and dependency,
• how Arthur Sackler went from liberal do-gooder to greedy capitalist,
• the polio vaccine and patenting the sun,
• how valium and anti-depressants were marketed to men and women differently,
• how the AIDS cocktail was developed,
• how Viagra® was discovered,
• why patents and intellectual property rights do not lead to more innovation,
• the prospects for a COVID-19 vaccine,
• the current state of the opioid crisis and how to stem it.

Gerald Posner is an award-winning journalist who has written twelve books, including the Pulitzer Prize finalist Case Closed: Lee Harvey Oswald and the Assassination of JFK and multiple national bestsellers. His 2015 book, God’s Bankers, a two-hundred-year history of the finances of the Vatican, was an acclaimed New York Timesbestseller. Posner has written for many national magazines and papers, including The New York Times, The New Yorker, Newsweek, and Time, and he has been a regular contributor to NBC, the History Channel, CNN, CBS, MSNBC, and FOX News. He lives in Miami Beach with his wife, author Trisha Posner.

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