The Metabolic Link - podcast cover

The Metabolic Link

Dr. Dominic D'Agostino PhD, Dr. Angela Poff PhD, and Victoria Fieldthemetaboliclink.buzzsprout.com
Welcome to The Metabolic Link, a medical and science podcast that explores the common thread of metabolism in health and disease. Join Dr. Dominic D'Agostino PhD, Dr. Angela Poff PhD, and Victoria Field as they dive into the latest research on metabolic health and therapy alongside some of the world’s leading experts. They'll also discuss how this science is being applied in the real world. This is where science meets society.
Last refreshed:
Download Metacast podcast app
Podcasts are better in Metacast mobile app
Don't just listen to podcasts. Learn from them with transcripts, summaries, and chapters for every episode. Skim, search, and bookmark insights. Learn more

Episodes

Journal Club: The Rise of Fatty Liver Disease and its Metabolic Roots | Ep.66

Become a member of The Metabolic Initiative to access exclusive ad-free episodes, 100s of videos on metabolic health, and earn CMEs: https://membership.metabolicinitiative.com In today's journal club episode, co-hosts of The Metabolic Link , Dr. Angela Poff and Dr. Dominic D'Agostino, unpack the startling rise of non-alcoholic fatty liver disease (NAFLD)—a silent epidemic affecting millions worldwide. Tune in as they break down groundbreaking new research revealing how NAFLD isn't just impacting...

Apr 23, 202559 minEp. 66

The Metabolic Impact of GLP-1s on Obesity | Spencer Nadolsky, DO | Ep.65

Join us for a FREE Live Q&A with Dr. Spencer Nadolsky on April 22nd at 9am PT / 12pm ET! Your first seven days are free, and as a member of The Metabolic Initiative, you’ll gain access to exclusive, ad-free episodes, hundreds of expert-led videos on metabolic health and therapy, CME opportunities, and more here! In this episode of The Metabolic Link, Dr. Dominic D’Agostino sits down with Dr. Spencer Nadolsky—board-certified obesity and lipid specialist, former NCAA heavyweight wrestler, and ...

Apr 11, 20251 hrEp. 65

Reversing Heart Disease Through Metabolic Health | Philip Ovadia, MD | Ep.64

Join us for a Live Q&A with Dr. Ovadia on March 31st at 12 PM PT / 3 PM ET! Your first seven days are free, and as a member of The Metabolic Initiative, you’ll gain access to exclusive, ad-free episodes, hundreds of videos on metabolic health (including Dr. Ovadia’s presentation, Fanning the Flames: Inflammation, Insulin Resistance, and Heart Disease), CME opportunities, and more. Register here! Dr. Philip Ovadia is a cardiac surgeon on a mission to change how we think about heart disease. A...

Mar 25, 20251 hr 7 minEp. 64

The Mitochondrial Link to Mental Illness | Ana Andreazza, PhD | The Metabolic Link Ep.63

Mitochondria do more than power our cells—they may hold the key to understanding and treating mental illness. In this episode of The Metabolic Link, Dr. Dominic D’Agostino sits down with Dr. Ana Andreazza, a leading expert in mitochondrial health at the University of Toronto. Dr. Andreazza has pioneered research linking mitochondrial dysfunction to psychiatric disorders like bipolar disorder, utilizing groundbreaking 3D brain organoid models to study neurotransmission. She also leads research on...

Mar 11, 20251 hr 5 minEp. 63

Optimizing Metabolic Health | MHS Panel Discussion | The Metabolic Link Ep. 62

Become a member of The Metabolic Initiative to access exclusive ad-free episodes, 100s of videos on metabolic health, and earn CMEs here . What’s the best way to optimize metabolic health? In this powerhouse episode of The Metabolic Link, we bring together leading experts including Dr. Ben Bikman, Dr. Richard Johnson, Dr. Jonathan Jun, Dr. Nick Norwitz, and Dave Feldman from our Optimizing Metabolic Health Symposium filmed at Metabolic Health Summit 2024 and hosted by Dr. Dominic D'Agostino. In ...

Feb 27, 202537 minEp. 62

Targeting Cancer Metabolism: The Future of Oncology | Dr. Tomás Duraj | The Metabolic Link Ep. 61

What if we could target cancer at its metabolic core? In this episode of The Metabolic Link, Dr. Dominic D’Agostino is joined by Dr. Tomás Duraj, a physician and cancer metabolism researcher working alongside Dr. Thomas Seyfried. Dr. Duraj is the lead author of a groundbreaking review on ketogenic metabolic therapy for glioblastoma, bringing together leading experts to explore how metabolic strategies could reshape cancer treatment. In this deep-dive conversation, they discuss the bioenergetics ...

Feb 11, 20251 hr 32 minEp. 62

A Ketogenic Approach to Type 1 Diabetes | Dr. Ian Lake | The Metabolic Link Ep.60

Become a member of The Metabolic Initiative to access exclusive ad-free episodes, 100s of videos on metabolic health, and earn CMEs: https://membership.metabolicinitiative.com Can a ketogenic diet revolutionize the management of type 1 diabetes? In this episode of The Metabolic Link, Dr. Ian Lake, a UK-based physician and type 1 diabetes advocate, shares his personal and professional journey in using low-carb and ketogenic diets to improve metabolic control. Diagnosed with type 1 diabetes at 36,...

Jan 29, 20251 hr 7 minEp. 61

Chad Vanags | Patient Perspective: Why I Don’t Trust You & How We Can Fix It | The Metabolic Link Ep.59

Become a member of The Metabolic Initiative to access exclusive ad-free episodes, watch 100s of videos on metabolic health, and earn CMEs here . In this powerful and unfiltered episode of The Metabolic Link, we're sharing a full presentation by Chad Vanags, a former SaaS executive and entrepreneur who has turned his stage 4 lung cancer diagnosis into a mission to reshape the way we think about healing. Recorded live at Metabolic Health Summit in January of 2024, Chad shares his journey of becomi...

Jan 14, 202542 minEp. 59

Journal Club: The Ketogenic Diet Reshapes Cancer Metabolism & the Gut Microbiome | Ep.58

Become a member of The Metabolic Initiative to access exclusive ad-free episodes and earn CMEs here . In this journal club episode, host Victoria Field is joined by Dr. Angela Poff and Dr. Dominic D’Agostino to dive into two groundbreaking studies shaping our understanding of metabolism and its role in health and disease. The team explores the nuances of a recent randomized controlled trial on ketogenic diets, free sugar restriction, and their effects on glucose tolerance, lipid metabolism, and ...

Dec 31, 20241 hr 11 minEp. 58

Thriving Beyond Schizophrenia: A Story of Healing with Metabolic Therapy | Lauren Kennedy West | Ep.57

Join our free Live Q&A with Lauren on December 18th and become a member of The Metabolic Initiative to access exclusive ad-free episodes and earn CMEs. Register here ! In this episode of The Metabolic Link, host Victoria Field sits down with Lauren Kennedy West, a passionate mental health advocate and social worker who was diagnosed with schizoaffective disorder in 2016. Lauren reveals her extraordinary journey of using metabolic therapy to not only manage but reverse debilitating symptoms, ...

Dec 16, 20241 hr 3 minEp. 57

The Science of Allulose | MHS Panel Discussion | The Metabolic Link Ep.56

Become a member of The Metabolic Initiative to access exclusive ad-free episodes and earn CMEs: https://membership.metabolicinitiative.com In this special episode of The Metabolic Link , we’re sharing an exclusive panel discussion from Metabolic Health Summit 2024, where leading experts dive into the science and real-world applications of allulose, a natural low-calorie sweetener with potential metabolic health benefits. Featuring insights from Dr. Richard Johnson, Dr. Jeff Volek, Dr. Ben Bikman...

Dec 10, 202459 minEp. 56

Fasting Mimicking Diet cycles, longevity and age-related diseases | Valter Longo, PhD | The Metabolic Link Ep.55

Become a member of The Metabolic Initiative to access exclusive ad-free episodes and earn CMEs. Your first 7 days are free! PLUS use code blackfriday at checkout to receive 50% off your first 3 months (through November 29th): https://membership.metabolicinitiative.com In this episode of The Metabolic Link filmed at Metabolic Health Summit 2024, Dr. Valter Longo shares his latest research on the fasting mimicking diet (FMD) and its powerful impact on aging, metabolic diseases, and cancer treatmen...

Nov 26, 20241 hr 15 minEp. 55

The Clinical Impact of Ketogenic Therapy in Epilepsy & Mental Illness | Beth Zupec-Kania, RDN, CD | The Metabolic Link Ep.54

Become a member of The Metabolic Initiative to access exclusive ad-free episodes and earn CMEs. Your first 7 days are free! PLUS use code blackfriday at checkout to receive 50% off your first 3 months (through November 29th): https://membership.metabolicinitiative.com In this episode of the Metabolic Link podcast, we are joined by Beth Zupec-Kania, an experienced dietitian and nutritionist with over 30 years in the field of ketogenic metabolic therapy. Beth has played a pivotal role in the devel...

Nov 19, 20241 hrEp. 54

Testing the Lipid Energy Model: Oreos vs Statins | Nick Norwitz, PhD | The Metabolic Link Ep. 53

Become a member of The Metabolic Initiative to access exclusive ad-free episodes and earn CMEs: https://membership.metabolicinitiative.com In this episode, we're sharing a presentation from Metabolic Health Summit 2024 that dives into a groundbreaking experiment titled "Oreo vs. Statin," by researcher-educator Nick Norwitz, PhD. What started as a personal journey with metabolic health turned into a captivating exploration of the lipid energy model and lean mass hyper responders. Dr. Norwitz shar...

Nov 07, 202424 minEp. 53

FoodFight USA: The Battle Against Ultra-Processed Foods | Todd Wagner | The Metabolic Link Ep.52

Did you know that nearly 60% of the average American's diet is made up of ultra-processed foods? This staggering statistic highlights a growing public health crisis linked to rising obesity rates and chronic diseases, not only in adults but our children too. In this week’s episode of The Metabolic Link, we dive into a critical conversation with Todd Wagner, a passionate advocate for food safety and health reform. As the founder of FoodFight USA, Todd is dedicated to cleaning up America’s tainted...

Oct 22, 20241 hr 18 minEp. 52

Journal Club: Metabolic Overdrive in Bipolar Disorder | The Metabolic Link Ep.51

Become a member of The Metabolic Initiative to access exclusive ad-free episodes and earn CMEs here . In this journal club episode of The Metabolic Link, we explore the cutting-edge "Metabolic Overdrive Hypothesis" with Dr. Dominic D'Agostino, Dr. Angela Poff, and Victoria Field, diving into the brain’s energy dysregulation in bipolar disorder. The featured paper, "The Metabolic Overdrive Hypothesis: Hyperglycolysis and Glutaminolysis in Bipolar Mania", by authors Dr. Iain Campbell and Dr. Harry...

Oct 08, 202459 minEp. 51

C15: The Essential Fatty Acid Transforming Metabolic Health & Aging | Dr. Stephanie Venn-Watson | Ep.50

In our 50th episode of The Metabolic Link podcast, host Dr. Dominic D’Agostino dives deep into the fascinating world of metabolic health through an unexpected lens — bottlenose dolphins. Dr. Stephanie Venn-Watson, a veterinary epidemiologist and public health scientist, joins the show to share her groundbreaking research with the U.S. Navy’s Marine Mammal Program, where dolphins helped reveal the essential role of C15:0. C15:0 is an odd-chain saturated fatty acid that has 3-times more cellular b...

Sep 24, 20241 hr 7 minEp. 50

Jeff Volek, PhD, RD | Exploring the Keto-Adapted Phenotype: Focus on Muscle | The Metabolic Link Ep.49

Become a member of The Metabolic Initiative to access exclusive ad-free episodes and earn CMEs: https://membership.metabolicinitiative.com In this episode of The Metabolic Link, recorded at Metabolic Health Summit 2024, we share Dr. Jeff Volek's full presentation where he takes a deep dive into the "Keto-Adapted Phenotype" with a focus on muscle. Dr. Volek, a leading expert in low-carbohydrate and ketogenic diets, shares groundbreaking research on how ketones impact muscle function and performan...

Sep 10, 202451 minEp. 49

Nick Norwitz, PhD | The Future of Medicine & Metabolic Health | The Metabolic Link Ep.48

Join Dr. Norwitz for a Live Q&A on September 10th at 12pm PT/3pm ET on The Metabolic Initiative platform! Visit this link to register, and also watch his presentation Cookies & Cholesterol Controversy inside the platform (first 7-days are free): https://membership.metabolicinitiative.com/norwitz In this episode, Dr. Nick Norwitz returns to The Metabolic Link podcast to explore the future of personalized medicine and the evolution of metabolic health research with host, Dr. Dominic D’Agos...

Aug 27, 20241 hr 20 minEp. 48

Dr. Chris Palmer | Brain Energy: The Metabolic Theory of Mental Illness | The Metabolic Link Ep. 47

Become a member of The Metabolic Initiative to access a robust bank of cutting edge metabolic health content, private ad-free podcast episodes, and earn CMEs here ! More than a billion people around the world suffer from mental and neurological disorders, and the numbers are escalating rapidly. Current treatments often fail to provide relief, resulting in many patients struggling with persistent symptoms and resistance to available therapies. In this episode, we’re sharing a full presentation by...

Aug 13, 20241 hr 5 minEp. 47

Infections, Inflammation, and Alzheimer's Disease with Mary Newport, MD | The Metabolic Link Ep.46

Become a member of The Metabolic Initiative to access exclusive ad-free episodes and earn CMEs here ! In this enlightening episode of The Metabolic Link, Dr. Dominic D'Agostino sits down with Dr. Mary Newport to delve into the world of Alzheimer's disease, discussing her pioneering work with ketogenic metabolic therapy. Dr. Newport shares her personal and inspiring journey with her husband, Steve, whose battle with early-onset Alzheimer's led her to discover the life-changing effects of MCT and ...

Jul 30, 20242 hr 7 minEp. 46

Metabolic Therapy for Serious Mental Illness | Dr. Deanna Kelly, Pharm.D., BCPP | The Metabolic Link Ep.45

Become a member of The Metabolic Initiative for ad-free episodes and CMEs In this episode of The Metabolic Link, host Victoria Field interviews Dr. Deanna Kelly, a distinguished professor of psychiatry at the University of Maryland School of Medicine. Dr. Kelly is pioneering nutritional interventions to treat serious mental illness and led a groundbreaking trial on the ketogenic diet for schizophrenia, the only inpatient study of its kind in the U.S. Unfortunately, this privately funded trial wa...

Jul 16, 202458 minEp. 45

Dr. Robert Lustig | Obesogens: The Hidden Driver of Obesity | The Metabolic Link Ep. 44

Become a member of The Metabolic Initiative to access exclusive episodes and earn CMEs: https://membership.metabolicinitiative.com In this episode of the Metabolic Link Podcast, host Dr. Dom D'Agostino sits down with Dr. Robert Lustig to discuss groundbreaking research unifying different models of obesity. They dive deep into the flaws of the traditional energy balance and carbohydrate-insulin models and introduce a compelling integrative theory encompassing the impact of obesogens, redox biolog...

Jul 02, 202457 minEp. 44

Take Control of Your Metabolic Health with Dr. Casey Means | The Metabolic Link Ep. 43

Become a member of The Metabolic Initiative to access exclusive episodes and earn CMEs: https://membership.metabolicinitiative.com In this interview, host Victoria Field sits down with Dr. Casey Means, a Stanford-trained physician, entrepreneur, and New York Times bestselling author of the new book Good Energy. Dr. Means shares her inspiring journey from being a head and neck surgeon to leaving traditional medicine and becoming a leading voice in the metabolic health field. They take a deep dive...

Jun 18, 20241 hr 16 minEp. 43

Lily Nichols, RDN, CDE | Optimizing Pregnancy and Metabolic Health | The Metabolic Link Ep.42

Become a member of The Metabolic Initiative to access exclusive episodes and earn CMEs! Registered dietitian, Lily Nichols, RDN, CDE, is back on The Metabolic Link, this time in an intimate interview that dives into the critical links between metabolic health, perinatal nutrition, and long-term wellbeing. This episode dives deep into how nutrition during the childbearing years can affect not only mothers but their children throughout their lives. Lily, who is also a New York Times bestselling au...

Jun 04, 202422 minEp. 42

Mitochondrial Health and Urolithin A with Dr. Anurag Singh | The Metabolic Link Ep. 41

Become a member of The Metabolic Initiative to access exclusive episodes and earn CMEs! Join us in this enlightening episode as we dive deep into the emerging research behind Urolithin A and its impact on mitochondrial health with Dr. Anurag Singh, a leading expert in the field and the Chief Medical Officer of Timeline. The discussion spans various facets of Urolithin A, from its origin in pomegranates and other foods to its potential in improving mitochondrial health, muscle strength, and reduc...

May 21, 202453 minEp. 41

Dr. Nina Teicholz | Beyond the Diet Wars: A Deep Dive into Nutrition Science | The Metabolic Link Ep.40

Become a member of The Metabolic Initiative for exclusive episodes and earn CMEs! Dive into the core of nutrition science with Dr. Dominic D'Agostino and Dr. Nina Teicholz, and uncover the remarkable benefits of saturated fats, unravel the complexities of LDL cholesterol, and dig into the heated debate surrounding food addiction and ethical meat consumption. Dr. Teicholz sheds light on the misunderstood facets of dietary fats, debunking prevalent myths about cholesterol, highlighting potential d...

May 07, 20241 hr 8 minEp. 40

A Biological Switch that Drives Obesity, Diabetes, and Dementia with Richard Johnson, MD | The Metabolic Link Ep. 39

Become a member of The Metabolic Initiative for exclusive episodes and to earn CMEs In this episode, recorded at Metabolic Health Summit 2024, Dr. Richard Johnson dives into the groundbreaking research that has uncovered the central role of fructose in driving the epidemics of obesity, diabetes, and a wide range of other metabolic diseases. Dr. Johnson presents compelling evidence that fructose, a seemingly innocuous sugar, is in fact a key trigger for activating a powerful biological survival s...

Apr 23, 202455 minEp. 39

Journal Club: Exploring Immune Response to Diet: Vegan vs Ketogenic Ep. 38

In this episode of The Metabolic Link, Victoria Field, Dr. Dominic D'Agostino, and Dr. Angela Poff dive into a fascinating new paper that compares the metabolic and immune impacts of ketogenic and vegan diets in humans. The study, titled “Differential Peripheral Immune Signatures Elicited by Vegan Versus Ketogenic Diets in Humans” takes a deep dive into the multi-omic effects of these two very different dietary approaches. The researchers found that just two weeks on a ketogenic diet significant...

Apr 09, 202451 minEp. 38

BioMolecular Athlete: Advanced Tools For Enhanced Human Performance with Andy Galpin, PhD | The Metabolic Link Ep. 37

The following Metabolic Link episode was originally filmed at Metabolic Health Summit 2024 and we're excited to share it with you today in its entirety! In this presentation, Dr. Andy Galpin, a human performance scientist, shares his insights on utilizing scientific principles, specifically the 'Biomolecular Athlete' concept, to achieve athletic excellence. He emphasizes the importance of individualized strategies that consider sleep, diet, stress, respiratory rates, and blood chemistry. The dis...

Mar 26, 20241 hr 29 minEp. 37
Hosted on Buzzsprout
For the best experience, listen in Metacast app for iOS or Android