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The Metabolic Link

Dr. Dominic D'Agostino PhD, Dr. Angela Poff PhD, and Victoria Fieldthemetaboliclink.buzzsprout.com
Welcome to The Metabolic Link, a medical and science podcast that explores the common thread of metabolism in health and disease. Join Dr. Dominic D'Agostino PhD, Dr. Angela Poff PhD, and Victoria Field as they dive into the latest research on metabolic health and therapy alongside some of the world’s leading experts. They'll also discuss how this science is being applied in the real world. This is where science meets society.
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Episodes

Ketogenic Diet’s Impact on Health and Performance with Jeff Volek, PhD | The Metabolic Link Ep. 36

This week’s episode of The Metabolic Link features an illuminating sit-down interview with Dr. Jeff Volek, a professor at The Ohio State University. With a PhD in Kinesiology specializing in exercise and nutrition science from Penn State University, Dr. Volek has performed cutting edge research on how humans adapt to diets restricted in carbohydrates with a dual focus on clinical and performance applications of nutritional ketosis. His scholarly work includes more than 300 peer-reviewed scientif...

Mar 04, 202423 minEp. 36

Fat: Why it Matters and What to Do About It with Ben Bikman, PhD | The Metabolic Link Ep. 35

This week's episode of The Metabolic Link features a full presentation from Metabolic Health Summit 2024. Dr. Ben Bikman, professor at Brigham Young University, dives deep into the intricacies of fat and its relationship to metabolic health. This is the full presentation he delivered at Metabolic Health Summit 2024 in Clearwater Beach, Florida. In it he shares his expertise on the link between body fat, insulin resistance, and chronic diseases such as obesity and diabetes. Throughout this talk, ...

Feb 26, 202444 minEp. 35

Change Your Diet, Change Your Mind: Ketogenic Therapy for Mental Health with Dr. Georgia Ede | The Metabolic Link Ep. 34

This week’s episode of The Metabolic Link features an illuminating sit-down interview with Dr. Georgia Ede, a Harvard-trained psychiatrist specializing in nutrition science and brain metabolism. With over 25 years of clinical experience, including 12 years as a college psychiatrist and nutrition consultant at Smith College and Harvard University Health Services, Dr. Ede was the first to offer students nutrition-based approaches as an alternative to psychiatric medications. She speaks internation...

Feb 14, 202418 minEp. 34

Recapping Metabolic Health Summit 2024 with Dr. Dominic D'Agostino, Dr. Angela Poff, and Victoria Field

In this episode of The Metabolic Link, Dr. Dominic D’Agostino, Dr. Angela Poff, and Victoria Field recap Metabolic Health Summit 2024, the world’s leading medical and scientific conference on metabolic health. Listen to this episode to get an inside look at the top scientific highlights and surprising moments from the perspective of the hosts who made it happen. Want to learn about all the cutting-edge research and scientific insights on metabolic health and therapy that you won’t find anywhere ...

Feb 06, 202426 minEp. 33

Understanding The Lean Mass Hyper Responder w/ Dr. Nick Norwitz and Dave Feldman | The Metabolic Link Ep. 32

We’ve just launched an extra and exciting episode of The Metabolic Link podcast! It features an eye-opening conversation between our host Dominic D’Agostino PhD, and guests Dave Feldman and Dr. Nick Norwitz, two researchers and MHS 2024 speakers spearheading investigations into the lean mass hyperresponder (LMHR) phenotype. Dave Feldman is a software engineer who became deeply interested in lipidology after seeing his cholesterol spike on a low-carb, high-fat diet. He has since performed self-ex...

Jan 12, 20241 hr 7 minEp. 32

Metabolic Consequences of Disrupted Sleep w/ Dr. Jonathan Jun | The Metabolic Link Ep. 31

This week’s episode of The Metabolic Link features an illuminating conversation between our host Dr. Dominic D’Agostino and Dr. Jonathan Jun, a pulmonary critical care and sleep medicine physician at Johns Hopkins. He is an expert in the diagnosis and treatment of sleep-disordered breathing, and in the care of critically ill patients in the Medical ICU. He is a member of the Sleep Fellowship Program Evaluation and Clinical Competency Committee and provides teaching to medical students and reside...

Jan 09, 202449 minEp. 31

How Allulose Aids Metabolism & Fructose Fuels Cancer | Journal Club | The Metabolic Link Ep. 30

In this episode, our co-hosts Dr. Dominic D’Agostino, Dr. Angela Poff, and Victoria Field discuss two recent scientific papers on the metabolic effects of allulose and how blocking fructose intake may help fight cancer. The first paper examines how allulose consumption influences metabolic factors like appetite, blood sugar, and insulin sensitivity through the release of key gut hormones and effects on carbohydrate digestion and metabolism. The second paper reviews multiple lines of evidence lin...

Dec 19, 202354 minEp. 30

Optimizing Metabolic Health After Cancer Diagnosis w/ Chad Vanags | The Metabolic Link Ep. 29

This week’s episode of The Metabolic Link features an illuminating conversation between our host Dr. Dom D’Agostino and Chad Vanags, a successful entrepreneur who is navigating a stage 4 cancer diagnosis with courage and purpose. After being diagnosed with stage 4 lung cancer in 2022 at just 39 years old, Chad has been documenting his journey to becoming “metabolically, physically, and mentally elite” to continue pursuing his life's vision. In this wide-ranging discussion, we cover: 💪 Chad's ba...

Dec 05, 20231 hr 12 minEp. 29

Keys To Making The Ketogenic Diet Work In The Real World w/ Franziska Spritzler | The Metabolic Link Ep. 28

This week’s episode of The Metabolic Link features an illuminating conversation between our host Dominic D'Agostino, PhD, and Franziska Spritzler, RD, CDE. Franziska is a registered dietitian and certified diabetes educator who specializes in low-carb and ketogenic diets. She has been following a low-carb approach for over a decade. In this episode, we cover: 💡 The essential tools Franziska uses when helping clients adhere to low-carb diets 💡 Managing and interpreting changes in blood work on ...

Nov 22, 202356 minEp. 28

Mood + Mindfulness | Journal Club | The Metabolic Link Ep. 27

In this episode, our co-hosts Victoria Field, Dr. Dominic D'Agostino, and Dr. Angela Poff discuss two recent scientific papers on the potential metabolic connections to psychiatric disorders and mindfulness-based interventions. The first paper is a systematic review on the efficacy of low-carb and ketogenic diets for treating mood and anxiety disorders. They discuss the importance in defining what constitutes a low-carb or ketogenic diet in research studies. Our hosts also discuss the limited da...

Nov 06, 20231 hr 5 minEp. 27

The Six Pillars of Health | Dr. Kyle Gillett | The Metabolic Link Ep. 26

This week’s episode of The Metabolic Link features an illuminating conversation between our host Dr. Dominic D'Agostino and Dr. Kyle Gillett, a board-certified physician in family and obesity medicine who provides holistic care to his patients. He earned his medical degree at the University of Kansas School of Medicine, practices at the Gillett Health Clinic in Olathe, Kansas, and is the host of The Gillett Health Podcast. His practice focuses on preventive, integrative, and precision medicine a...

Oct 24, 20231 hr 26 minEp. 26

Evidence-Based Prenatal Nutrition | Lily Nichols | Metabolic Link Ep. 25

This week's episode of The Metabolic Link features an eye-opening discussion between Metabolic Health Summit organizer Victoria Field and prenatal nutrition expert Lily Nichols , RDN, CDE. Lily is the author of two bestselling books - Real Food for Pregnancy and Real Food for Gestational Diabetes. Her work focuses on evidence-based, critical analysis of conventional pregnancy nutrition recommendations. In this episode, we cover: Evaluating macronutrient needs in pregnancy, including research sug...

Oct 10, 20231 hr 2 minEp. 25

The Emerging Field of Metabolic Psychiatry | Dr. Shebani Sethi | Metabolic Link Ep. 24

In this week’s episode of The Metabolic Link, double board certified psychiatrist and obesity medicine physician, Dr. Shebani Sethi, takes us on a deep dive into the emerging field of metabolic psychiatry. Dr. Shebani Sethi is a psychiatrist and obesity medicine physician at Stanford University School of Medicine. She is the founding director of the Stanford Metabolic Psychiatry Clinic, where she researches dietary and pharmacological interventions to improve metabolic health and mental illness....

Sep 28, 20238 minEp. 24

Metabolic Interventions For Cognitive Resilience in Aging | Abbi Hernandez, PhD | The Metabolic Link Ep. 23

This week’s episode of The Metabolic Link features an illuminating conversation between our host Dominic D’Agostino, PhD, and Dr. Abbi Hernandez, an assistant professor at the University of Alabama at Birmingham. Dr. Hernandez received her PhD from the University of Florida, where she studied age and diet related changes in neurological function and cognitive health. Her research has focused on investigating the potential of ketogenic diets and time-restricted feeding for preventing age-related ...

Sep 13, 202355 minEp. 23

The Metabolic Underpinnings of Bipolar Disorder | Iain Campbell, PhD & Matt Baszucki | The Metabolic Link Ep. 22

In this week’s episode, host Victoria Field speaks with Matt Baszucki and Dr. Iain Campbell about their lived experiences with bipolar disorder and the therapeutic effects of the ketogenic diet, potential root causes of the mental illness, and their mission to spread awareness and education around ketogenic dietary therapy as a treatment for bipolar disorder. Iain Campbell, PhD, is the Baszucki Research Fellow in Metabolic Psychiatry at the University of Edinburgh. He has a PhD in Global Health ...

Aug 29, 20231 hr 11 minEp. 22

Warburg Effect in Sporadic Alzheimer's & Ketogenic Therapy for MS Patients | Journal Club | The Metabolic Link Ep. 21

In this episode, our co-hosts Victoria Field, Dominic D’Agostino, PhD, and Angela Poff, PhD, discuss two recent scientific studies that focus on the potential metabolic connections to neurodegenerative diseases. Study 1: Warburg-like metabolic transformation underlies neuronal degeneration in sporadic Alzheimer’s disease The study delves into the molecular changes causing a neuron's transition from healthy to degenerative, as seen in sporadic Alzheimer's, which is the most prevalent form of Alzh...

Aug 16, 20231 hr 20 minEp. 21

Dr. Jeff Volek, PhD, RD | Ketogenic Diet and Human Performance | The Metabolic Link Ep.20

This week’s episode of The Metabolic Link features an in-depth conversation between our host Dominic D’Agostino, PhD, and Jeff Volek, PhD, RD, on a wide range of topics as well as questions submitted by our Twitter followers! Dr. Volek is a registered dietitian and professor in the Department of Human Sciences at The Ohio State University. For the last 25 years, he has performed translational research on how humans adapt to ketogenic diets with a dual focus on clinical and performance applicatio...

Jul 31, 20231 hr 15 minEp. 20

Ketogenic Therapy for Epilepsy | Kelly Faltersack MS, RDN, LDN, CD | The Metabolic Link Ep.19

On this week’s episode of The Metabolic Link, our host and MHS Co-organizer Victoria Field interviewed Kelly Faltersack, a registered dietitian nutritionist, who specializes in treating patients with ketogenic diet therapy as an effective treatment for epilepsy and other neurological disorders. Kelly Faltersack MS, RDN, LDN, CD is a registered dietitian nutritionist at UW Health in Madison, Wisconsin. Kelly has over 10 years of experience as a registered dietitian nutritionist, and five years of...

Jul 19, 202346 minEp. 19

Satchin Panda, PhD | Circadian Rhythm and Metabolic Health | The Metabolic Link Ep.18

This week’s episode of The Metabolic Link features an enlightening conversation between our host Dr. Dominic D’Agostino and Dr. Satchin Panda, PhD on the fascinating connection between time-restricted eating , circadian rhythm , and metabolic health . A leading expert in the field of circadian rhythm research, Dr. Panda is a professor at the Salk Institute for Biological Studies and a founding executive member of the Center for Circadian Biology at the University of California. Have you been hea...

Jul 05, 202328 minEp. 18

Ketogenic Therapy for Mental Illness | Nicole Laurent, LMHC | The Metabolic Link Ep.17

This week’s episode of The Metabolic Link features an interview with Nicole Laurent, a Licensed Mental Health Counselor who helps her clients use ketogenic dietary therapy as a treatment for mental illness and neurological issues. Nicole was one of seven pioneers of Metabolic Psychiatry recognized by the Baszucki Brain Research Fund and the Milken Institute with the Metabolic Mind Award in 2022. What is Metabolic Psychiatry? Metabolic psychiatry is an emerging field that focuses on targeting and...

Jun 20, 20231 hr 12 minEp. 17

The Impact of Hyperglycemia in Stroke and Aerobic Exercise in Alzheimer’s | The Metabolic Link Ep.16

In this Journal Club episode, The Metabolic Link Hosts Dr. Dominic D’Agostino, Dr. Angela Poff, and Victoria Field review recent research uncovering the potential impact of high blood glucose on stroke outcomes and the positive influence of exercise on Alzheimer’s disease. An ischemic stroke happens when a blood vessel in the brain is occluded. This prevents oxygen and nutrients from reaching a region of the brain, ultimately causing some of that tissue to die. A hemorrhagic stroke occurs when a...

Jun 06, 202348 minEp. 16

The Metabolic Management of Migraines | Elena Gross, PhD | The Metabolic Link Ep. 15

It’s said that more than one billion individuals around the world suffer from migraines each year. A migraine isn’t your average headache. It’s often completely debilitating and may include sensitivity to light and sound, vomiting, severe pain, and other symptoms that can wreak havoc on quality of life. Despite being one of the most common neurological disorders on the planet with a high prevalence in (particularly female) young adults, many of those troubled by migraines do not receive effectiv...

May 23, 202355 minEp. 15

Kwadwo Kyeremanteng, MD | An ICU Perspective on Metabolic Health | The Metabolic Link Ep.14

On this episode of The Metabolic Link, we’re sitting down with Dr. Kwadwo Kyeremanteng to discuss his experience as a critical care physician during 2020, the importance of metabolic health in fighting viral infections, and how improving global metabolic health will make us more resilient against future illnesses. Dr. Kyeremanteng is an ICU doctor and intensivist at The Ottawa Hospital who seeks to increase the efficiency of medical care with cost-effectiveness, dignity, and justice in mind whil...

May 09, 202311 minEp. 14

Light Exposure, Sleep Quality, & Cardiometabolic Function | Journal Club | The Metabolic Link Ep.13

You won’t be surprised to hear that a night of poor sleep can affect how good you feel the next day. But did you know that disruptions in sleep quality, especially when they occur chronically, can have a major negative impact on your cognitive function, mood, and overall metabolic health? On this week’s Journal Club episode of The Metabolic Link, co-hosts Dr. Dominic D’Agostino, Dr. Angela Poff, and Victoria Field dive into two research publications exploring how meal timing in shift workers aff...

Apr 25, 202339 minEp. 13

Tommy Wood, MD, PhD | Optimizing Human Health & Cognition | The Metabolic Link Ep.12

On this week’s episode of The Metabolic Link, host Dr. Dominic D’Agostino is sitting down with neuroscientist, Tommy Wood, MD, PhD, to discuss optimizing human health and cognitive function. In this interview, Dom explores a wide variety of fascinating topics with Dr. Wood. They uncover why cognitive demand may be important in preventing devastating neurological disorders like dementia, the importance of monitoring cardiovascular risk biomarkers including insulin, ApoB, homocysteine, and the pot...

Apr 11, 20231 hr 55 minEp. 12

Jaime Seeman, MD | Women’s Metabolic Health Through the Life Stages | The Metabolic Link Ep.11

On this week’s episode of The Metabolic Link, we’re sitting down with OBGYN and Ketogenic Metabolic Therapy Expert, Jaime Seeman, MD, to discuss the importance of metabolic health through a woman's life stages. In this interview, we explore how and why a woman might want to optimize their metabolic health in their fertile years, into menopause, and beyond. We also uncover the specific issues women can face along the way, the potential of metabolic therapy in improving hormone function, the uniqu...

Apr 04, 202315 minEp. 11

Ketosis in Models of Muscle Atrophy | Journal Club | The Metabolic Link Ep.10

On this week’s Journal Club episode of The Metabolic Link, co-hosts Dr. Dominic D’Agostino, Dr. Angela Poff, and Victoria Field discuss two seemingly conflicting research studies exploring the effects of ketosis on muscle health in models of atrophy. Atrophy refers to the wasting of a body tissue or organ that occurs due to the degeneration of cells. Atrophy of vital tissues such as the skeletal muscle occurs in numerous pathological catabolic conditions, such as in cancer cachexia, motor neuron...

Mar 28, 202342 minEp. 10

Ben Bikman, PhD | Reversing Insulin Resistance | The Metabolic Link Ep.9

On this week’s episode of The Metabolic Link, Dr. Dominic D’Agostino is sitting down with world-renowned metabolic scientist, Ben Bikman, PhD, to explore the ins and outs of insulin resistance, Type 2 Diabetes Mellitus (T2DM), and ways to manage, and even reverse, both. In this discussion, Dr. Bikman makes a case for why testing fasting insulin should be a part of the diagnostic and treatment equation when addressing T2DM, the difference between pathological and physiological insulin resistance,...

Mar 21, 20231 hr 13 minEp. 9

Metabolic Therapy for Parkinson’s & Mental Illness | Journal Club | The Metabolic Link Ep.8

In this Journal Club episode, The Metabolic Link Hosts Dr. Dominic D’Agostino, Dr. Angela Poff, and Victoria Field review recent research exploring the use of ketogenic metabolic therapy in Parkinson’s Disease and Mental Illness. The first study discussed investigates the effects of a ketogenic diet applied prior to versus after the onset of Parkinson’s disease in an animal model. Parkinson’s disease is a highly prevalent disease, with over 6 million people worldwide who suffer from it. We under...

Mar 14, 20231 hrEp. 8

L.J. Amaral, M.S., R.D., CSO | Implementing Metabolic Therapy for Cancer | The Metabolic Link Ep.7

On this week’s episode of The Metabolic Link, we’re sitting down with Oncology Dietitian, L.J. Amaral for a fascinating conversation that explores implementing metabolic therapy, such as the ketogenic diet, within oncology. In this episode, we dive into why she started using metabolic therapy for cancer, how she implements it with patients at Cedars-Sinai, and the kind of results she’s seen in using it. We also cover some of the most difficult obstacles in starting a ketogenic diet in the face o...

Mar 07, 202343 minEp. 7
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