Join The Lancet Neurology’s In Conversation With… as editors Elena Becker-Barroso and Laura Hart welcome Henry Brodaty and Alice Powell from the University of New South Wales (Sydney, Australia) to discuss cognitive resilience and ageing. This episode teases apart cognitive resilience, cognitive reserve, brain maintenance, and brain reserve; explores how social determinants, life-course factors, and vascular health shape resilience; and delves into robust measures, biomarkers, and how pathologie...
Apr 17, 2026•23 min•Ep. 2
In this episode, Laura Hart and Elena Becker-Barroso speak with Niklas Mattsson-Carlgren (Lund University) about the use of blood biomarkers in the diagnosis and stratification of Alzheimer's disease. They discuss two particular plasma biomarkers—p-tau217 and eMTBR-tau243—including what they measure and how a proposed practical two-step approach that uses p-tau217 as an initial screen in a neurology clinic, and then eMTBR-tau243 for those who test positive, could support diagnostic decisions. Cl...
Mar 18, 2026•16 min
In this episode, Senior Editor Morgane Boillot speaks with Professor Cristina Tassorelli (University of Pavia, Italy) about recent advances in migraine prevention. Together with colleagues, Tassorelli has authored a Review in the journal examining the major developments in migraine-specific pharmacological treatments over the past decade, with a particular focus on therapies targeting the CGRP pathway. In this conversation, they explore what these advances mean for people living with migraine an...
Feb 18, 2026•24 min
Our Editor-in-Chief, Elena Becker-Barroso, speaks with Inga Zerr (DZNE, Göttingen, Germany) and Simon Mead (UCL London, UK) about the latest advances in prion diseases. In collaboration with other experts, Zerr and Mead have authored a Series in the journal that covers the genetic factors behind these diseases, and new diagnostic and prognostic biomarkers. Click here to read the full articles: https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(25)00451-X/fulltext https://www.thelanc...
Jan 21, 2026•30 min
Host Morgane Boillot chats with Dr Julia Greenland about a clinical trial of azathioprine in early Parkinson's disease. Click here to read the full article: https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(25)00386-2/fulltext Medical imaging and theranostics are revolutionising how we diagnose, treat, and understand disease. To meet this moment, The Lancet group is happy to announce the launch of, The Lancet Medical Imaging and Theranostics. You can visit https://www.thelancet.com...
Dec 19, 2025•15 min
In this episode, host Antonia Eisenkoeck, speaks with Ian McKeith, Emeritus Professor of Old Age Psychiatry at Newcastle University, UK. They delve into the history of dementia with Lewy bodies research, highlighting key milestones and breakthroughs. Discover insights into the current state of the field and what the future holds for understanding and treating this condition. Click here to read the full articles of this series: https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(25)00...
Nov 12, 2025•17 min
In this episode, host Laura Hart chats with Ask Nordestgaard (Brigham and Women's Hospital, Boston, USA) about the long-term risk of stroke in healthy women, the role of inflammation and lipoproteins, and how early biomarker screening could transform stroke prevention strategies. Click here to read the full article . Medical imaging and theranostics are revolutionising how we diagnose, treat, and understand disease. To meet this moment, The Lancet group is happy to announce the launch of, The La...
Oct 15, 2025•12 min
Morgane Boillot chats with Professor Shiv Saidha (Johns Hopkins University, USA) about recent developments in diagnosing multiple sclerosis, and specifically on the use of paraclinical tests of the optic nerve in this context. Read the full article: https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(25)00270-4/fulltext?dgcid=buzzsprout_icw_podcast_September_25_laneur Medical imaging and theranostics are revolutionising how we diagnose, treat, and understand disease. To meet this mom...
Sep 17, 2025•30 min
People with Down syndrome face a high risk of developing Alzheimer’s disease, which is the leading cause of death in this population over the age of 35. In this episode, Morgane Boillot (Senior Editor) is joined by Professor Michael Rafii to explore the intersection of Down syndrome and Alzheimer’s disease. They discuss the latest research into disease pathology, biomarkers, and clinical trials, and examine the key challenges and future opportunities in understanding and treating Alzheimer’s dis...
Aug 13, 2025•23 min
In this episode, host Laura Hart chats with Professor Amit Bar-Or (University of Pennsylvania) about the potential of the BTK inhibitor fenebrutinib in treating relapsing multiple sclerosis, highlighting future challenges in MS research. Read the full article: https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(25)00174-7/fulltext?dgcid=buzzsprout_icw_podcast_July_25_laneur Medical imaging and theranostics are revolutionising how we diagnose, treat, and understand disease. To meet th...
Jul 16, 2025•9 min
Sarah Passey is joined by Dr Marte-Helene Bjørk (Haukeland University Hospital, Norway) to discuss the latest evidence and practical guidance on managing reproductive risks in people with epilepsy, including medication safety, pregnancy planning, and global challenges in care. Read the full article: https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(25)00130-9/fulltext?dgcid=buzzsprout_icw_podcast_June_25_laneur Medical imaging and theranostics are revolutionising how we diagnose, t...
Jun 17, 2025•21 min
Assistant Editor Sam Griffiths is joined by Professor Geoff Manley (UCSF, CA, USA) to discuss his new NIH-NINDS classification of acute TBI, the limitations of traditional classifications, how the new framework was developed, and what it means for the future of TBI research and patient care. Read the full article: https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(25)00154-1/fulltext?dgcid=buzzsprout_icw_podcast_May_25_laneur Medical imaging and theranostics are revolutionising how ...
May 20, 2025•26 min
Increasing numbers of people are surviving stroke but with motor impairments that can contribute substantially to long-term disability. Transcranial direct current stimulation has shown promise in reducing motor impairment when combined with rehabilitation therapy. Sarah Passey talks to Wayne Feng (Duke University School of Medicine, Durham, NC, USA) about his latest trial, TRANSPORT2, which assesses transcranial direct current stimulation in combination with modified constraint-induced movement...
Apr 16, 2025•20 min
In this podcast, linked to the April 2025 issue of The Lancet Neurology , Laura Hart (Deputy Editor) chats to Marialuisa Gandolfi (University of Verona in Italy) about advances in the classification and management of pain in Parkinson’s disease. Medical imaging and theranostics are revolutionising how we diagnose, treat, and understand disease. To meet this moment, The Lancet group is happy to announce the launch of, The Lancet Medical Imaging and Theranostics. You can visit https://www.thelance...
Mar 19, 2025•13 min
Sarah Passey ( The Lancet Neurology ) is joined by Michael Tymianski (University Health Network, Toronto, Canada) to discuss an Article in the March issue reporting a meta-analysis looking at neuroprotection in stroke and what can be learnt for future research. Read the full article: https://www.thelancet.com/journals/laneur/article/PiiS1474-4422(24)00515-5/fulltext?dgcid=buzzsprout_icw_podcast_generic_laneur Medical imaging and theranostics are revolutionising how we diagnose, treat, and unders...
Feb 19, 2025•26 min
In this podcast, linked to the February 2025 issue of The Lancet Neurology , Elena Becker-Barroso (Editor-in-Chief) chats to Elizabeth Finger (Western University, London, ON, Canada) about the FOXY trial of oxytocin for apathy in people with frontotemporal dementia. Read the full article: https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(24)00456-3/fulltext?dgcid=buzzsprout_icw_podcast_generic_laneur Medical imaging and theranostics are revolutionising how we diagnose, treat, and u...
Jan 22, 2025•19 min
The Lancet Neurology Editors take a look back at advances in neurology in 2024, as highlighted by experts in a series of Round-ups published in the January issue. Medical imaging and theranostics are revolutionising how we diagnose, treat, and understand disease. To meet this moment, The Lancet group is happy to announce the launch of, The Lancet Medical Imaging and Theranostics. You can visit https://www.thelancet.com/medical-imaging-theranostics to learn more. Continue this conversation on soc...
Dec 18, 2024•18 min
Florian Krismer (Innsbruck Medical University) and Elizabeth Coon (Mayo Clinic) join Sarah Passey ( The Lancet Neurology ) to discuss their Review paper on multiple system atrophy, which is published in the December issue of The Lancet Neurology . Medical imaging and theranostics are revolutionising how we diagnose, treat, and understand disease. To meet this moment, The Lancet group is happy to announce the launch of, The Lancet Medical Imaging and Theranostics. You can visit https://www.thelan...
Nov 20, 2024•18 min
Professor Suvankar Pal (University of Edinburgh) joins Sarah Passey (Senior Editor at The Lancet Neurology ) to discuss the first findings from the MND-SMART trial of treatments for motor neuron disease. The Article is published in the November issue of The Lancet Neurology . Medical imaging and theranostics are revolutionising how we diagnose, treat, and understand disease. To meet this moment, The Lancet group is happy to announce the launch of, The Lancet Medical Imaging and Theranostics. You...
Oct 16, 2024•19 min
Prof Jorge Correale and Dr Lilyana Amezcua talk to The Lancet Neurology about their Personal View papers, published in the October 2024 issue, on the differential diagnosis of multiple sclerosis in regions outside North America and Western Europe and in people from minority ethnic or racial backgrounds in North America, northern Europe, and Australasia. Read the full article: https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(24)00256-4/fulltext?dgcid=buzzsprout_icw_podcast_generic_...
Sep 18, 2024•20 min
Dr Alex Iranzo joins The Lancet Neurology to discuss his recent Review on the association between sleep disorders and Parkinson's disease. The Review is published in the August issue of The Lancet Neurology . Read the full article: https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(24)00170-4?dgcid=buzzsprout_icw_podcast_generic_laneur Medical imaging and theranostics are revolutionising how we diagnose, treat, and understand disease. To meet this moment, The Lancet group is happy t...
Aug 14, 2024•18 min
Dr Adrian Owen joins Sarah Passey to chat about a his Personal View, published in the August 2024 issue of The Lancet Neurology , about detecting awareness after an acute brain injury. Medical imaging and theranostics are revolutionising how we diagnose, treat, and understand disease. To meet this moment, The Lancet group is happy to announce the launch of, The Lancet Medical Imaging and Theranostics. You can visit https://www.thelancet.com/medical-imaging-theranostics to learn more. Continue th...
Jul 17, 2024•18 min
Dr Glenn Nielsen joins Lauren Southwell to discuss the Physio4FMD trial of specialist physiotherapy for people with functional motor disorder in England and Scotland. This Article is published in the July issue of The Lancet Neurology . Medical imaging and theranostics are revolutionising how we diagnose, treat, and understand disease. To meet this moment, The Lancet group is happy to announce the launch of, The Lancet Medical Imaging and Theranostics. You can visit https://www.thelancet.com/med...
Jun 12, 2024•16 min
Sanjay Sisodiya joins The Lancet Neurology to discuss the potential effects of climate change on brain health. The Personal View is published in the June issue of The Lancet Neurology . Medical imaging and theranostics are revolutionising how we diagnose, treat, and understand disease. To meet this moment, The Lancet group is happy to announce the launch of, The Lancet Medical Imaging and Theranostics. You can visit https://www.thelancet.com/medical-imaging-theranostics to learn more. Continue t...
May 15, 2024•22 min
Jacqueline French and Jacob Pellinen join Senior Editor Sarah Passey to discuss recent progress made in the diagnosis of epilepsy and challenges that remain. Their Review on this topic is published in the May issue of The Lancet Neurology . Read the full article: https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(24)00079-6/fulltext?dgcid=buzzsprout_icw_podcast_generic_laneur Medical imaging and theranostics are revolutionising how we diagnose, treat, and understand disease. To meet...
Apr 15, 2024•24 min
Jaimie Steinmetz and Theo Vos from the Institute for Health Metrics and Evaluation, and Katrin Seeher and Tarun Dua from WHO, join Heather Brown and Lauren Southwell to discuss new data on the global, regional, and national burden of disorders affecting the nervous system. The Article is published in the April issue of The Lancet Neurology . Medical imaging and theranostics are revolutionising how we diagnose, treat, and understand disease. To meet this moment, The Lancet group is happy to annou...
Mar 14, 2024•26 min
Giovanni Frisoni joins The Lancet Neurology to discuss new European intersocietal recommendations for the biomarker-based diagnosis of neurocognitive disorders. The Personal View is published in the March issue of The Lancet Neurology. Read the full article: https://www.thelancet.com/journals/laneur/article/S1474-4422(23)00447-7/fulltext?dgcid=buzzsprout_icw_podcast_generic_laneur Medical imaging and theranostics are revolutionising how we diagnose, treat, and understand disease. To meet this mo...
Feb 14, 2024•13 min
Marianne Chapleau and Gil Rabinovici join Senior Editor Sarah Passey to discuss their research on posterior cortical atrophy. The Article is published in the February issue of The Lancet Neurology . Read the full article: https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(23)00414-3/fulltext?dgcid=buzzsprout_icw_podcast_generic_laneur Medical imaging and theranostics are revolutionising how we diagnose, treat, and understand disease. To meet this moment, The Lancet group is happy to...
Jan 22, 2024•23 min
Cecilia Åkerlund and David Nelson join The Lancet Neurology to discuss their research on clinical variables that might distinguish how the disease process progresses in people with traumatic brain injury. The Article is published in the January issue of The Lancet Neurology. Read the full article: https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(23)00358-7/fulltext?dgcid=buzzsprout_icw_podcast_generic_laneur Medical imaging and theranostics are revolutionising how we diagnose, tre...
Dec 13, 2023•19 min
Rustam Al-Shahi Salman joins Senior Editor Sarah Passey to discuss the COCROACH meta-analysis findings, published in the December issue of The Lancet Neurology , of the effects of oral anticoagulation in people with atrial fibrillation after spontaneous intracranial haemorrhage. Read the full article: https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(23)00315-0/fulltext?dgcid=buzzsprout_icw_podcast_generic_laneur Medical imaging and theranostics are revolutionising how we diagnose,...
Nov 15, 2023•25 min
